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The map label for this gene is pbpG [H]

Identifier: 86747168

GI number: 86747168

Start: 40187

End: 42394

Strand: Direct

Name: pbpG [H]

Synonym: RPB_0041

Alternate gene names: 86747168

Gene position: 40187-42394 (Clockwise)

Preceding gene: 86747166

Following gene: 86747170

Centisome position: 0.75

GC content: 68.75

Gene sequence:

>2208_bases
ATGGCGGTGGGCAAGAAGAAAGCCGGCGAACGGCGGGAGCCGAAATTCGGCTTGGCCGACTCGCTGTCCGGCCTGCGCCT
CAACCCGCAGGACCGGATCAGCGTGGCCGACGACGACCGGCCGAAAAAGCCCAGAGCTGCCAAAGCGCAACCCGCCAGAT
CCTCGGGCGGCGGCGGGTCGCGCAAGCCGCGCGGAAAATCCCGCAGCAAAGGCGGACTGCGCCGCCTCGTCACCCGCACC
GTGTACTGGACCGCCGTCGCCGGCATCTGGGCGGTGCTGGCGGTGGTCGGGCTGATGGTCTGGGTCGGCGCGCATCTGCC
GCCGATCCAGTCGCTGGAAATTCCGAAGCGACCGCCGACCATTACCATCGTCGCCGCCGATGGCAGTCAGCTCGCGGTGC
GCGGCGAGATGGCCGGCACCAATGTGGCGCTGAAGGAATTGCCGCCTTATCTGCCGAAGGCTTTCATCGCCATCGAGGAC
CGGCGCTTCTATCAGCATTTCGGCGTCGATCCGATCGGCATCGGCCGCGCCGCGATCGCCAATGTGCTGCATCGCGGCGT
GTCGCAGGGCGGCTCGACGCTCACCCAGCAGCTCGCCAAGAACCTGTTCCTGACCCAGGACCGCACCCTGATGCGCAAGC
TGCAGGAGGTCGAACTGGCGCTGTGGCTGGAGCGCAAGCATTCCAAGGCGGAGATTCTCGAACTGTATCTCAACCGGGTG
TATTTCGGCTCCGGCGCCTACGGCATCGAGGCGGCGTCGCAGAAATATTTCGGCAAGTCGGCCAAGGACGTCACCCTGGT
CGAGGCGGCGATGCTCGCCGGCCTGGTCAAATCGCCGTCGCGGCTGGCGCCGAACCGCAATCCGGAGGGCGCCGAGAAGC
GCGCCCAGCTGGTGCTCGCCGCAATGGCCGACGCCGATTTCATCACCGACAAGCAGGCCCGCACCGCGATCGCCAACCCG
GTCTACACCGTCAAGCCGACCGGCGCCGGCACCATCAACTACGTCGCCGACTGGATCGGCGAGGTGCTCGACGACCTGGT
CGGACAGATCGATCAGTCGATCGTGGTGGAGACCTCGATCGATCCGAAGCTGCAGGCGGAAGCCGAAGCCGCGATCATCG
ACGAACTCGCCGCCAAGAGCGTCAAGTTCAAGGTCTCGCAAGGCGCGCTGGTGGCGATGACGCCGGACGGCGCGGTGCGG
GCGATGATCGGCGGCCGCAACTACGCCGAGAGCCAGTTCAACCGCGCCGTCACCGCCAAGCGGCAGCCGGGCTCGGCATT
CAAGCCGTTCGTGTATCTCACGGCGATCGAGGCCGGGCTGACGCCGGAGACGATCCGGCAGGACGCGCCGCTCGACGTCA
AGGGCTGGCGGCCGGAGAATTACACCCATGAGTACTTCGGCTCGGTGACGCTGACCCAGGCGCTGTCGATGTCGCTCAAC
ACCGTGGCGGTGCGGCTCGGGCTCGAGGTCGGGCCGAAGAACGTGGTGCGCACCGCGCACCGGCTCGGCATCGCCTCCAA
GCTCGAGGCCAACGCCTCGATCGCGCTCGGCACCTCGGAAGTGTCGGTGCTGGAGCTGGTCGGCGCCTATGCGCCTTTCG
CCAATGGCGGGCTGGCGGCGTCGCCGCATGTCGTCGACCGGATCCGCACCGCGAGCGGCAACAAGCTGCTGTATGCCCGG
CCGAACGATCCGCCGAACCGCGTCGTCGATGCCCGTGCGGTGGCGATGATGAACACCATGATGCGGGAGACGCTGCAGTC
CGGCACCGCGAAGAAGGCCGACGTTCCGGGCTGGACCGCCGCCGGCAAGACCGGCACCAGCCAGGATTTCCGCGACGCCT
GGTTCATCGGCTACACCGGGACGCTGGTCACCGGCGTCTGGCTCGGCAATGACGACAATTCGCCGACCCGGAAGGCGACC
GGCGGCGGCCTGCCGGTCGACGTCTGGACCCGCTTCATGCGCGAGGCGCTGAAAGGCACCGCGCCGCAGCCGCTACCCGG
CGGCGGCTGGAGCGGCGGCCCGCTGGTCGCAGGCAGCCCCTCCGCCGGCGGCACCATCGCGCAGGCCGGCCCGCGCGGCG
AAACCCAGATCGTCAACATCCCTGCGGCTTCCGGCGCCGCTCGCCCGCAGCCCGCCCGCGCCAATGTCCGCCCCGAAGCC
GACAGCGGCCTCGACGGCTGGCTGATGGACCGGCTGTTCGGGCGATAG

Upstream 100 bases:

>100_bases
CGACTTCGCCGGAACCTTGGAACCCGACCTTAACCATCGCTTTACCGGGCCTTAAACCCACTCCGTTACGGTCCCGCATC
GGTCGGCGTGGGCGTTGCGA

Downstream 100 bases:

>100_bases
CGTTCGCCCGCAATGAGGGCCGTGCTCGCATCGCCCCCACCCTCACCCTGATGTCGAGGATTGCGGCGGCGCTCTCTTTA
CCCTCCCCTGGAGGGGGAGG

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 735; Mature: 734

Protein sequence:

>735_residues
MAVGKKKAGERREPKFGLADSLSGLRLNPQDRISVADDDRPKKPRAAKAQPARSSGGGGSRKPRGKSRSKGGLRRLVTRT
VYWTAVAGIWAVLAVVGLMVWVGAHLPPIQSLEIPKRPPTITIVAADGSQLAVRGEMAGTNVALKELPPYLPKAFIAIED
RRFYQHFGVDPIGIGRAAIANVLHRGVSQGGSTLTQQLAKNLFLTQDRTLMRKLQEVELALWLERKHSKAEILELYLNRV
YFGSGAYGIEAASQKYFGKSAKDVTLVEAAMLAGLVKSPSRLAPNRNPEGAEKRAQLVLAAMADADFITDKQARTAIANP
VYTVKPTGAGTINYVADWIGEVLDDLVGQIDQSIVVETSIDPKLQAEAEAAIIDELAAKSVKFKVSQGALVAMTPDGAVR
AMIGGRNYAESQFNRAVTAKRQPGSAFKPFVYLTAIEAGLTPETIRQDAPLDVKGWRPENYTHEYFGSVTLTQALSMSLN
TVAVRLGLEVGPKNVVRTAHRLGIASKLEANASIALGTSEVSVLELVGAYAPFANGGLAASPHVVDRIRTASGNKLLYAR
PNDPPNRVVDARAVAMMNTMMRETLQSGTAKKADVPGWTAAGKTGTSQDFRDAWFIGYTGTLVTGVWLGNDDNSPTRKAT
GGGLPVDVWTRFMREALKGTAPQPLPGGGWSGGPLVAGSPSAGGTIAQAGPRGETQIVNIPAASGAARPQPARANVRPEA
DSGLDGWLMDRLFGR

Sequences:

>Translated_735_residues
MAVGKKKAGERREPKFGLADSLSGLRLNPQDRISVADDDRPKKPRAAKAQPARSSGGGGSRKPRGKSRSKGGLRRLVTRT
VYWTAVAGIWAVLAVVGLMVWVGAHLPPIQSLEIPKRPPTITIVAADGSQLAVRGEMAGTNVALKELPPYLPKAFIAIED
RRFYQHFGVDPIGIGRAAIANVLHRGVSQGGSTLTQQLAKNLFLTQDRTLMRKLQEVELALWLERKHSKAEILELYLNRV
YFGSGAYGIEAASQKYFGKSAKDVTLVEAAMLAGLVKSPSRLAPNRNPEGAEKRAQLVLAAMADADFITDKQARTAIANP
VYTVKPTGAGTINYVADWIGEVLDDLVGQIDQSIVVETSIDPKLQAEAEAAIIDELAAKSVKFKVSQGALVAMTPDGAVR
AMIGGRNYAESQFNRAVTAKRQPGSAFKPFVYLTAIEAGLTPETIRQDAPLDVKGWRPENYTHEYFGSVTLTQALSMSLN
TVAVRLGLEVGPKNVVRTAHRLGIASKLEANASIALGTSEVSVLELVGAYAPFANGGLAASPHVVDRIRTASGNKLLYAR
PNDPPNRVVDARAVAMMNTMMRETLQSGTAKKADVPGWTAAGKTGTSQDFRDAWFIGYTGTLVTGVWLGNDDNSPTRKAT
GGGLPVDVWTRFMREALKGTAPQPLPGGGWSGGPLVAGSPSAGGTIAQAGPRGETQIVNIPAASGAARPQPARANVRPEA
DSGLDGWLMDRLFGR
>Mature_734_residues
AVGKKKAGERREPKFGLADSLSGLRLNPQDRISVADDDRPKKPRAAKAQPARSSGGGGSRKPRGKSRSKGGLRRLVTRTV
YWTAVAGIWAVLAVVGLMVWVGAHLPPIQSLEIPKRPPTITIVAADGSQLAVRGEMAGTNVALKELPPYLPKAFIAIEDR
RFYQHFGVDPIGIGRAAIANVLHRGVSQGGSTLTQQLAKNLFLTQDRTLMRKLQEVELALWLERKHSKAEILELYLNRVY
FGSGAYGIEAASQKYFGKSAKDVTLVEAAMLAGLVKSPSRLAPNRNPEGAEKRAQLVLAAMADADFITDKQARTAIANPV
YTVKPTGAGTINYVADWIGEVLDDLVGQIDQSIVVETSIDPKLQAEAEAAIIDELAAKSVKFKVSQGALVAMTPDGAVRA
MIGGRNYAESQFNRAVTAKRQPGSAFKPFVYLTAIEAGLTPETIRQDAPLDVKGWRPENYTHEYFGSVTLTQALSMSLNT
VAVRLGLEVGPKNVVRTAHRLGIASKLEANASIALGTSEVSVLELVGAYAPFANGGLAASPHVVDRIRTASGNKLLYARP
NDPPNRVVDARAVAMMNTMMRETLQSGTAKKADVPGWTAAGKTGTSQDFRDAWFIGYTGTLVTGVWLGNDDNSPTRKATG
GGLPVDVWTRFMREALKGTAPQPLPGGGWSGGPLVAGSPSAGGTIAQAGPRGETQIVNIPAASGAARPQPARANVRPEAD
SGLDGWLMDRLFGR

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=547, Percent_Identity=33.0895795246801, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1788867, Length=580, Percent_Identity=31.3793103448276, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082258, Length=284, Percent_Identity=40.4929577464789, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI1789601, Length=155, Percent_Identity=40, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 78277; Mature: 78146

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGKKKAGERREPKFGLADSLSGLRLNPQDRISVADDDRPKKPRAAKAQPARSSGGGGS
CCCCCCCCCCCCCCCCCHHHCCCCCEECCHHCEEECCCCCCCCCCCCCCCCCCCCCCCCC
RKPRGKSRSKGGLRRLVTRTVYWTAVAGIWAVLAVVGLMVWVGAHLPPIQSLEIPKRPPT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
ITIVAADGSQLAVRGEMAGTNVALKELPPYLPKAFIAIEDRRFYQHFGVDPIGIGRAAIA
EEEEECCCCEEEEEECCCCCCEEHHHCCCCCCCEEEEEECHHHHHHCCCCCCCCCHHHHH
NVLHRGVSQGGSTLTQQLAKNLFLTQDRTLMRKLQEVELALWLERKHSKAEILELYLNRV
HHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YFGSGAYGIEAASQKYFGKSAKDVTLVEAAMLAGLVKSPSRLAPNRNPEGAEKRAQLVLA
EECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHH
AMADADFITDKQARTAIANPVYTVKPTGAGTINYVADWIGEVLDDLVGQIDQSIVVETSI
HHHCCHHHCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
DPKLQAEAEAAIIDELAAKSVKFKVSQGALVAMTPDGAVRAMIGGRNYAESQFNRAVTAK
CCCHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHCC
RQPGSAFKPFVYLTAIEAGLTPETIRQDAPLDVKGWRPENYTHEYFGSVTLTQALSMSLN
CCCCCCCCCEEEEEEHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHH
TVAVRLGLEVGPKNVVRTAHRLGIASKLEANASIALGTSEVSVLELVGAYAPFANGGLAA
EEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCC
SPHVVDRIRTASGNKLLYARPNDPPNRVVDARAVAMMNTMMRETLQSGTAKKADVPGWTA
CCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGKTGTSQDFRDAWFIGYTGTLVTGVWLGNDDNSPTRKATGGGLPVDVWTRFMREALKGT
CCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
APQPLPGGGWSGGPLVAGSPSAGGTIAQAGPRGETQIVNIPAASGAARPQPARANVRPEA
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
DSGLDGWLMDRLFGR
CCCCHHHHHHHHHCC
>Mature Secondary Structure 
AVGKKKAGERREPKFGLADSLSGLRLNPQDRISVADDDRPKKPRAAKAQPARSSGGGGS
CCCCCCCCCCCCCCCCHHHCCCCCEECCHHCEEECCCCCCCCCCCCCCCCCCCCCCCCC
RKPRGKSRSKGGLRRLVTRTVYWTAVAGIWAVLAVVGLMVWVGAHLPPIQSLEIPKRPPT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
ITIVAADGSQLAVRGEMAGTNVALKELPPYLPKAFIAIEDRRFYQHFGVDPIGIGRAAIA
EEEEECCCCEEEEEECCCCCCEEHHHCCCCCCCEEEEEECHHHHHHCCCCCCCCCHHHHH
NVLHRGVSQGGSTLTQQLAKNLFLTQDRTLMRKLQEVELALWLERKHSKAEILELYLNRV
HHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YFGSGAYGIEAASQKYFGKSAKDVTLVEAAMLAGLVKSPSRLAPNRNPEGAEKRAQLVLA
EECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHH
AMADADFITDKQARTAIANPVYTVKPTGAGTINYVADWIGEVLDDLVGQIDQSIVVETSI
HHHCCHHHCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
DPKLQAEAEAAIIDELAAKSVKFKVSQGALVAMTPDGAVRAMIGGRNYAESQFNRAVTAK
CCCHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHCC
RQPGSAFKPFVYLTAIEAGLTPETIRQDAPLDVKGWRPENYTHEYFGSVTLTQALSMSLN
CCCCCCCCCEEEEEEHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHH
TVAVRLGLEVGPKNVVRTAHRLGIASKLEANASIALGTSEVSVLELVGAYAPFANGGLAA
EEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCC
SPHVVDRIRTASGNKLLYARPNDPPNRVVDARAVAMMNTMMRETLQSGTAKKADVPGWTA
CCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGKTGTSQDFRDAWFIGYTGTLVTGVWLGNDDNSPTRKATGGGLPVDVWTRFMREALKGT
CCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
APQPLPGGGWSGGPLVAGSPSAGGTIAQAGPRGETQIVNIPAASGAARPQPARANVRPEA
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
DSGLDGWLMDRLFGR
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]