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The map label for this gene is ctaD [H]

Identifier: 86610124

GI number: 86610124

Start: 2786310

End: 2788016

Strand: Direct

Name: ctaD [H]

Synonym: CYB_2698

Alternate gene names: 86610124

Gene position: 2786310-2788016 (Clockwise)

Preceding gene: 86610123

Following gene: 86610125

Centisome position: 91.45

GC content: 56.88

Gene sequence:

>1707_bases
ATGACCCAGCTGCAAGACAGCCCAAGACTTGTTGCTGCACCGAAGGTTGAACTTGAACTTCCTGCTGAGCCTTGGTGGCG
CTTCTTTACCTTCTCCACCGATCACAAGGTCATCGGGATCCAGTACTTGGTGACCACCTTTTTCTTCTACTTGGTGGGAG
GGGCGCTGGCGACGGCAGTACGGGCAGAGCTGGCTACTCCAGAGGCCGACTTTCTCGGCTTTGAGCGGTACAACGGTGCC
TTTACCCTGCACGCCACGATCATGATCTTTTTGTGGATCGTGCCTGCTTTGGTGGGGGGCTTTGGCAACTACCTGGTACC
GCTGATGATCGGGGCGCGGGATATGGCCTTCCCCAAGCTGAATGCAGTGGCCTTTTGGCTGGTTCCGCCCACAGGGATCC
TGCTTTTGGCCAGCCTGTTCATAGAGGCTCCGGCTGCCGGCTGGACTTCCTACCCCCCCCTCAGCTTGATCAGCGGCAAG
GTGGGGGAAGAACTCTGGATCCTGAGCATTTTGTTGGCAGGAACCTCTTCCATCCTGGCGGCGGTTAACTTCATCACCAC
CATTCTGAAGATGCGCATGCCCGGCATGAAGATGGAAGACATGCCGCTGTTTTGCTGGGCCATGCTGGCAGCATCTATTC
TTACCCTCATTGCAACACCGGTTTTGGCTGGTGCGTTGATCTTGCTCAGCTTTGACCTGTTGGCGGGTACGGCCTTTTTC
AACCCCAGCGGCGGCGGGGATCCGGTGGTGTACCAGCACATGTTCTGGTTCTACTCCCACCCGGCGGTGTACATCATGAT
CTTGCCGGTCTTTGGCATGATCTCGGAGATTTTGCCGGTGCATGCCCGCAAGCCCATCTTTGCTTACAAAGCCATTGCCT
ATTCCAGCTTGGCCATCTGCTTTTTGGGGTTGATCGTCTGGGCGCACCACATGTTCACCAGCGGCACCCCTGACTGGATG
CGGGTGTTCTTCATGATCGCCACCATGGCCATTGCCGTTCCCACTGGGATCAAGGTGTTTAGCTGGCTGGCCACTTTGTG
GGGCGGCAAAATCCACTTCCGCTCGGCCATGCTGTTTGGCATGGGTTTTGTCTCGATGTTCGTGATCGGCGGCTTGAGCG
GGATTATCCTCGCCTCGGTGCCTCTGGATATCCACGTTCACGACACCTACTTTGTGGTGGCCCACCTACACTACGTGTTG
TTTGGCGGCAGCGTCTTTGGGATCTATGCCGGCATCTACCACTGGTTCCCCAAGATGACGGGGCGCATGTTGAATGAGTT
TTGGGGGCGGGTACATTTTGTGCTGACCTTCGTCGGCTTCAACATCTGCTTTCTGCCGATGCACAAGCTGGGCCTGATGG
GGATGCCCCGCCGGGTGGCCCAGTACGATCCCCAATTTGCCGACCTCAACTGGATCAGCTCGGTGGGGGCCTTTGTTCTG
GCCATTTCCACCCTGCCCTTTTTGGTTAACGCCATCTACTCCTGGGTGGCCGGGCCAAAAGCTGGGGATAATCCTTGGCA
GGCCCTGACACTGGAGTGGACAACTTCTTCTCCCCCGCCCCATCACAACTTTTATGGGGATCCCATTTTGCTGACCGGCC
CCTATGACTACGGTTTGCACAGCAAGGAGACGCTGGACTACTTTGCTGCTCAGTTGCAAACCTTGCGGGAGCTGGCGCTG
GCAGAAGCGGAGCCTACTTCTTCTTAG

Upstream 100 bases:

>100_bases
GATCCCTTCCTTCCGCAGGCTAGCTGGGATCCCTGACGCCCCTTTGGCCTGCGCTTGTGGGAACAACATTCTGCCAACGC
GATATAGGAGCTTTTGTGCA

Downstream 100 bases:

>100_bases
CAGGCCGGATGCCCGGTGGGCGGCTGATCCCCTGCTCACTGGGTATTCCAGTCTTGGCTGGGCTGCTTGTACAGCCTCAA
GAAGTCTCAGGAATTCAGGA

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTQLQDSPRLVAAPKVELELPAEPWWRFFTFSTDHKVIGIQYLVTTFFFYLVGGALATAVRAELATPEADFLGFERYNGA
FTLHATIMIFLWIVPALVGGFGNYLVPLMIGARDMAFPKLNAVAFWLVPPTGILLLASLFIEAPAAGWTSYPPLSLISGK
VGEELWILSILLAGTSSILAAVNFITTILKMRMPGMKMEDMPLFCWAMLAASILTLIATPVLAGALILLSFDLLAGTAFF
NPSGGGDPVVYQHMFWFYSHPAVYIMILPVFGMISEILPVHARKPIFAYKAIAYSSLAICFLGLIVWAHHMFTSGTPDWM
RVFFMIATMAIAVPTGIKVFSWLATLWGGKIHFRSAMLFGMGFVSMFVIGGLSGIILASVPLDIHVHDTYFVVAHLHYVL
FGGSVFGIYAGIYHWFPKMTGRMLNEFWGRVHFVLTFVGFNICFLPMHKLGLMGMPRRVAQYDPQFADLNWISSVGAFVL
AISTLPFLVNAIYSWVAGPKAGDNPWQALTLEWTTSSPPPHHNFYGDPILLTGPYDYGLHSKETLDYFAAQLQTLRELAL
AEAEPTSS

Sequences:

>Translated_568_residues
MTQLQDSPRLVAAPKVELELPAEPWWRFFTFSTDHKVIGIQYLVTTFFFYLVGGALATAVRAELATPEADFLGFERYNGA
FTLHATIMIFLWIVPALVGGFGNYLVPLMIGARDMAFPKLNAVAFWLVPPTGILLLASLFIEAPAAGWTSYPPLSLISGK
VGEELWILSILLAGTSSILAAVNFITTILKMRMPGMKMEDMPLFCWAMLAASILTLIATPVLAGALILLSFDLLAGTAFF
NPSGGGDPVVYQHMFWFYSHPAVYIMILPVFGMISEILPVHARKPIFAYKAIAYSSLAICFLGLIVWAHHMFTSGTPDWM
RVFFMIATMAIAVPTGIKVFSWLATLWGGKIHFRSAMLFGMGFVSMFVIGGLSGIILASVPLDIHVHDTYFVVAHLHYVL
FGGSVFGIYAGIYHWFPKMTGRMLNEFWGRVHFVLTFVGFNICFLPMHKLGLMGMPRRVAQYDPQFADLNWISSVGAFVL
AISTLPFLVNAIYSWVAGPKAGDNPWQALTLEWTTSSPPPHHNFYGDPILLTGPYDYGLHSKETLDYFAAQLQTLRELAL
AEAEPTSS
>Mature_567_residues
TQLQDSPRLVAAPKVELELPAEPWWRFFTFSTDHKVIGIQYLVTTFFFYLVGGALATAVRAELATPEADFLGFERYNGAF
TLHATIMIFLWIVPALVGGFGNYLVPLMIGARDMAFPKLNAVAFWLVPPTGILLLASLFIEAPAAGWTSYPPLSLISGKV
GEELWILSILLAGTSSILAAVNFITTILKMRMPGMKMEDMPLFCWAMLAASILTLIATPVLAGALILLSFDLLAGTAFFN
PSGGGDPVVYQHMFWFYSHPAVYIMILPVFGMISEILPVHARKPIFAYKAIAYSSLAICFLGLIVWAHHMFTSGTPDWMR
VFFMIATMAIAVPTGIKVFSWLATLWGGKIHFRSAMLFGMGFVSMFVIGGLSGIILASVPLDIHVHDTYFVVAHLHYVLF
GGSVFGIYAGIYHWFPKMTGRMLNEFWGRVHFVLTFVGFNICFLPMHKLGLMGMPRRVAQYDPQFADLNWISSVGAFVLA
ISTLPFLVNAIYSWVAGPKAGDNPWQALTLEWTTSSPPPHHNFYGDPILLTGPYDYGLHSKETLDYFAAQLQTLRELALA
EAEPTSS

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=502, Percent_Identity=47.609561752988, Blast_Score=411, Evalue=1e-115,
Organism=Escherichia coli, GI1786634, Length=509, Percent_Identity=42.8290766208251, Blast_Score=390, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6226519, Length=521, Percent_Identity=41.8426103646833, Blast_Score=406, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=44.3396226415094, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=40.650406504065, Blast_Score=176, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62833; Mature: 62702

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLQDSPRLVAAPKVELELPAEPWWRFFTFSTDHKVIGIQYLVTTFFFYLVGGALATAV
CCCCCCCCCEEECCCEEEECCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RAELATPEADFLGFERYNGAFTLHATIMIFLWIVPALVGGFGNYLVPLMIGARDMAFPKL
HHHHCCCCHHHCCHHHCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
NAVAFWLVPPTGILLLASLFIEAPAAGWTSYPPLSLISGKVGEELWILSILLAGTSSILA
CEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCHHHHHH
AVNFITTILKMRMPGMKMEDMPLFCWAMLAASILTLIATPVLAGALILLSFDLLAGTAFF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NPSGGGDPVVYQHMFWFYSHPAVYIMILPVFGMISEILPVHARKPIFAYKAIAYSSLAIC
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FLGLIVWAHHMFTSGTPDWMRVFFMIATMAIAVPTGIKVFSWLATLWGGKIHFRSAMLFG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
MGFVSMFVIGGLSGIILASVPLDIHVHDTYFVVAHLHYVLFGGSVFGIYAGIYHWFPKMT
HHHHHHHHHHCCHHHEEEECCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GRMLNEFWGRVHFVLTFVGFNICFLPMHKLGLMGMPRRVAQYDPQFADLNWISSVGAFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
AISTLPFLVNAIYSWVAGPKAGDNPWQALTLEWTTSSPPPHHNFYGDPILLTGPYDYGLH
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCC
SKETLDYFAAQLQTLRELALAEAEPTSS
CHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQLQDSPRLVAAPKVELELPAEPWWRFFTFSTDHKVIGIQYLVTTFFFYLVGGALATAV
CCCCCCCCEEECCCEEEECCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RAELATPEADFLGFERYNGAFTLHATIMIFLWIVPALVGGFGNYLVPLMIGARDMAFPKL
HHHHCCCCHHHCCHHHCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
NAVAFWLVPPTGILLLASLFIEAPAAGWTSYPPLSLISGKVGEELWILSILLAGTSSILA
CEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCHHHHHH
AVNFITTILKMRMPGMKMEDMPLFCWAMLAASILTLIATPVLAGALILLSFDLLAGTAFF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NPSGGGDPVVYQHMFWFYSHPAVYIMILPVFGMISEILPVHARKPIFAYKAIAYSSLAIC
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FLGLIVWAHHMFTSGTPDWMRVFFMIATMAIAVPTGIKVFSWLATLWGGKIHFRSAMLFG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
MGFVSMFVIGGLSGIILASVPLDIHVHDTYFVVAHLHYVLFGGSVFGIYAGIYHWFPKMT
HHHHHHHHHHCCHHHEEEECCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GRMLNEFWGRVHFVLTFVGFNICFLPMHKLGLMGMPRRVAQYDPQFADLNWISSVGAFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
AISTLPFLVNAIYSWVAGPKAGDNPWQALTLEWTTSSPPPHHNFYGDPILLTGPYDYGLH
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCC
SKETLDYFAAQLQTLRELALAEAEPTSS
CHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]