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The map label for this gene is msrB [H]

Identifier: 86610059

GI number: 86610059

Start: 2720921

End: 2721424

Strand: Direct

Name: msrB [H]

Synonym: CYB_2628

Alternate gene names: 86610059

Gene position: 2720921-2721424 (Clockwise)

Preceding gene: 86610051

Following gene: 86610060

Centisome position: 89.31

GC content: 59.33

Gene sequence:

>504_bases
ATGAACCTCATCATGCGACGACGCGAGCTGTTGACCTCGGCGGTGGCCGGGTTGATTACAGCACCCCTCAGCTTAGCAGG
AGAGCAAAGAGCAATGGCCCAACAGACTTATCCCTTCACCAAAACCGACGCCGAGTGGCGGCAACTGCTCACCGAAGAGC
AATACTATGTGCTGCGCCAAGAGGGCACTGAGCCCCCCTTCCGCAACGCTTACTACGACAACAAGGCCCCAGGTATCTAT
GTCTGTGCCGGCTGTGGTCAGGAGCTGTTTTCCTCGGCGGCCAAGTACGACAGTGGCACCGGTTGGCCCAGCTTTTGGGA
GCCGATTGCTCCCCATGTGATCGGTACCAAGACGGACTGGAAATTGTTTGTGCCCCGCACAGAAGTCCACTGCTCCAACT
GCGGCGGGCATTTGGGGCACGTGTTTCGGGATGGCCCCCCGCCCACGGGCTTGCGCTACTGCATCAATTCTGCTGCCCTC
AAGTTCATCCCAGCCACCGCCTAG

Upstream 100 bases:

>100_bases
GGGTAACCTGCTTGCAGGTCTCAACCCACAGGTGGCGGACAAAGGCGGATGGATCCCCCTAGTAGGGATGGCCTCCCCGC
CACTTACACAGCGACAACAG

Downstream 100 bases:

>100_bases
AAATCCTCTTGGCTCCAGCTAAAACTGAGCCGCCTGTCTGGGTGAGCCTATGTCGGACTACACGTTCCTGGATGCTGCTT
CGATTCTGCTGCGGGAGGGC

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNLIMRRRELLTSAVAGLITAPLSLAGEQRAMAQQTYPFTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIY
VCAGCGQELFSSAAKYDSGTGWPSFWEPIAPHVIGTKTDWKLFVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAAL
KFIPATA

Sequences:

>Translated_167_residues
MNLIMRRRELLTSAVAGLITAPLSLAGEQRAMAQQTYPFTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIY
VCAGCGQELFSSAAKYDSGTGWPSFWEPIAPHVIGTKTDWKLFVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAAL
KFIPATA
>Mature_167_residues
MNLIMRRRELLTSAVAGLITAPLSLAGEQRAMAQQTYPFTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIY
VCAGCGQELFSSAAKYDSGTGWPSFWEPIAPHVIGTKTDWKLFVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAAL
KFIPATA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=123, Percent_Identity=52.0325203252033, Blast_Score=136, Evalue=7e-33,
Organism=Homo sapiens, GI301336162, Length=123, Percent_Identity=52.0325203252033, Blast_Score=136, Evalue=7e-33,
Organism=Homo sapiens, GI73089054, Length=123, Percent_Identity=52.0325203252033, Blast_Score=136, Evalue=7e-33,
Organism=Homo sapiens, GI37620216, Length=123, Percent_Identity=52.0325203252033, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI117606353, Length=144, Percent_Identity=50, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI7706511, Length=98, Percent_Identity=41.8367346938776, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788077, Length=118, Percent_Identity=50.8474576271186, Blast_Score=130, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=120, Percent_Identity=46.6666666666667, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=42.8571428571429, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=157, Percent_Identity=36.3057324840764, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221378664, Length=135, Percent_Identity=42.962962962963, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24645799, Length=148, Percent_Identity=42.5675675675676, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI221378662, Length=142, Percent_Identity=41.5492957746479, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45553335, Length=140, Percent_Identity=43.5714285714286, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356369, Length=140, Percent_Identity=43.5714285714286, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645801, Length=157, Percent_Identity=40.1273885350318, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24645804, Length=151, Percent_Identity=41.0596026490066, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18572; Mature: 18572

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIMRRRELLTSAVAGLITAPLSLAGEQRAMAQQTYPFTKTDAEWRQLLTEEQYYVLRQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEC
EGTEPPFRNAYYDNKAPGIYVCAGCGQELFSSAAKYDSGTGWPSFWEPIAPHVIGTKTDW
CCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHCCCEECCCCCC
KLFVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAALKFIPATA
EEECCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNLIMRRRELLTSAVAGLITAPLSLAGEQRAMAQQTYPFTKTDAEWRQLLTEEQYYVLRQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEC
EGTEPPFRNAYYDNKAPGIYVCAGCGQELFSSAAKYDSGTGWPSFWEPIAPHVIGTKTDW
CCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHCCCEECCCCCC
KLFVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAALKFIPATA
EEECCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]