Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 86609575

GI number: 86609575

Start: 2222478

End: 2223875

Strand: Direct

Name: ygjG [C]

Synonym: CYB_2128

Alternate gene names: 86609575

Gene position: 2222478-2223875 (Clockwise)

Preceding gene: 86609574

Following gene: 86609577

Centisome position: 72.95

GC content: 59.08

Gene sequence:

>1398_bases
ATGCAAGAAACCCTGGAAAAAGCAGCCGTCGCCCTGCAAGCGGAGCTGAATCTGGAGCCTTTTTGGATGCCCTTTACGGC
CAATCGGCAATTTAAAGCCAACCCGCGCCTGTTGGTTGCCGCCCGAGACATGTATTACACCAGCCACGATGGACGCCAAA
TCCTAGATGGGACTGCCGGGCTGTGGTGTGTGAATGCCGGCCACTGCCGCCCCCCAATTGTGGAAGCGATCCAACAGCAG
GTGGCCCAACTGGACTACGCCCCAGCTTTTCAGATGGGCCATCCCAAAGCCTTTCTACTGGCGGAGCAGCTCATCCAGCT
CACCCCTGCCGGACTGGATCACGTTTTTTTCACCAACTCTGGCTCTGAGGCGGTGGATACGGCCCTGAAAATGGCCATCG
CCTACCATCGCTTACGCGGACAGGGATCCCGGCAGCGGCTGATTGGCCGAGAACGGGGCTACCACGGCGTTGGCTTTGGG
GGCATCTCGGTCGGGGGCATCTCCAACAACCGCAAGTTTTTCGGCAGCCTCATTCCCGGAGTGGATCACCTACCCCACAC
CCACAACCTGGAGCAAAACGCCTTTAGCCGCGGCCTGCCTCGCTGGGGATCCCACTTGGCAGAAGACTTGGAGCGGATCG
TCGCTCTCCACGATGCCAGCACGATTGCAGCGGTGATCGTAGAGCCGGTTGCCGGTTCAACGGGGGTGTTGCTGCCGCCG
GTGGGCTATTTGGAAAAGCTGCGGGCCATTTGCGACAAATACGGCATTCTGCTCATCTTCGATGAGGTGATCACCGGCTT
TGGGCGTCTGGGATCCCCTTTTGCGGCCAATTACTTTGGGGTGGTGCCGGATCTGATTTGCTGTGCCAAGGGCCTCACCA
ATGGCACCATCCCGATGGGCGCAGTGATCGTCAAGCAAGAGATCTACAGCGCCTTCATGGAGGCTGCTGGTTCCGCTGAT
GACCTGCACCGTCCAGGGGACAACAGCAGGACGCTGTCCTGGAGCCCCATCGAGTTTTTCCACGGCTACACCTACTCCGG
CCACCCAGTTGCCAGTGCCGCCGGCTTGGCTACCCTGAACCTGTATCGAGAAGAAGGCTTGTTCGAGCGGGCTGCCAACC
TCGCTCCCCTCTGGGAGGAGGCTCTCCATTCCCTACGGGGCTTGCCTCATGTCATCGATGTGCGCAACCTCGGCTTGGTG
GGGGCAATTGAATTGGAAGGGATCCCTGGCCGACCGACAGCGCGGGCTTTTGAAGCGTTTTTGCGCTGCTACGAGCGGGG
GGTATTGATTCGCACTACAGGTGATACCATTGCCCTTTCCCCGCCTTTGATCATCGAGGAAGCCCATATTGAACACCTGA
TCGCCACCCTGAAGCGAGTTCTTCAAGAGCTACCTTAG

Upstream 100 bases:

>100_bases
CGTTCCCGTTAGCAGGATGGAGCCCCTTTCAAAATTATCCAATATCCAGGGATTCCATCTTCGCCAGCTTGAAATCTCGT
CTACTGCCGGAGGGCCAGCC

Downstream 100 bases:

>100_bases
TCCTGAATCGACAAGAGAGACTGCCTGAGGGAGTTAGAAGCTTCTGGGGCTGGGCGTCGGCGAAGGACTGGGAGAGGGAC
TGGGTCTGGGCGAAGGGGAT

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQETLEKAAVALQAELNLEPFWMPFTANRQFKANPRLLVAARDMYYTSHDGRQILDGTAGLWCVNAGHCRPPIVEAIQQQ
VAQLDYAPAFQMGHPKAFLLAEQLIQLTPAGLDHVFFTNSGSEAVDTALKMAIAYHRLRGQGSRQRLIGRERGYHGVGFG
GISVGGISNNRKFFGSLIPGVDHLPHTHNLEQNAFSRGLPRWGSHLAEDLERIVALHDASTIAAVIVEPVAGSTGVLLPP
VGYLEKLRAICDKYGILLIFDEVITGFGRLGSPFAANYFGVVPDLICCAKGLTNGTIPMGAVIVKQEIYSAFMEAAGSAD
DLHRPGDNSRTLSWSPIEFFHGYTYSGHPVASAAGLATLNLYREEGLFERAANLAPLWEEALHSLRGLPHVIDVRNLGLV
GAIELEGIPGRPTARAFEAFLRCYERGVLIRTTGDTIALSPPLIIEEAHIEHLIATLKRVLQELP

Sequences:

>Translated_465_residues
MQETLEKAAVALQAELNLEPFWMPFTANRQFKANPRLLVAARDMYYTSHDGRQILDGTAGLWCVNAGHCRPPIVEAIQQQ
VAQLDYAPAFQMGHPKAFLLAEQLIQLTPAGLDHVFFTNSGSEAVDTALKMAIAYHRLRGQGSRQRLIGRERGYHGVGFG
GISVGGISNNRKFFGSLIPGVDHLPHTHNLEQNAFSRGLPRWGSHLAEDLERIVALHDASTIAAVIVEPVAGSTGVLLPP
VGYLEKLRAICDKYGILLIFDEVITGFGRLGSPFAANYFGVVPDLICCAKGLTNGTIPMGAVIVKQEIYSAFMEAAGSAD
DLHRPGDNSRTLSWSPIEFFHGYTYSGHPVASAAGLATLNLYREEGLFERAANLAPLWEEALHSLRGLPHVIDVRNLGLV
GAIELEGIPGRPTARAFEAFLRCYERGVLIRTTGDTIALSPPLIIEEAHIEHLIATLKRVLQELP
>Mature_465_residues
MQETLEKAAVALQAELNLEPFWMPFTANRQFKANPRLLVAARDMYYTSHDGRQILDGTAGLWCVNAGHCRPPIVEAIQQQ
VAQLDYAPAFQMGHPKAFLLAEQLIQLTPAGLDHVFFTNSGSEAVDTALKMAIAYHRLRGQGSRQRLIGRERGYHGVGFG
GISVGGISNNRKFFGSLIPGVDHLPHTHNLEQNAFSRGLPRWGSHLAEDLERIVALHDASTIAAVIVEPVAGSTGVLLPP
VGYLEKLRAICDKYGILLIFDEVITGFGRLGSPFAANYFGVVPDLICCAKGLTNGTIPMGAVIVKQEIYSAFMEAAGSAD
DLHRPGDNSRTLSWSPIEFFHGYTYSGHPVASAAGLATLNLYREEGLFERAANLAPLWEEALHSLRGLPHVIDVRNLGLV
GAIELEGIPGRPTARAFEAFLRCYERGVLIRTTGDTIALSPPLIIEEAHIEHLIATLKRVLQELP

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=434, Percent_Identity=29.2626728110599, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI37574042, Length=456, Percent_Identity=28.2894736842105, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442709, Length=416, Percent_Identity=28.3653846153846, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226442705, Length=452, Percent_Identity=27.6548672566372, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI284507298, Length=346, Percent_Identity=29.4797687861272, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI13994255, Length=455, Percent_Identity=25.9340659340659, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI24119277, Length=450, Percent_Identity=26.4444444444444, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI145693181, Length=417, Percent_Identity=32.1342925659472, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1786991, Length=451, Percent_Identity=31.7073170731707, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1789016, Length=430, Percent_Identity=29.0697674418605, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=29.3103448275862, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787560, Length=453, Percent_Identity=28.0353200883002, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788044, Length=408, Percent_Identity=27.9411764705882, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786349, Length=387, Percent_Identity=28.4237726098191, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=432, Percent_Identity=28.2407407407407, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=462, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=455, Percent_Identity=27.6923076923077, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=305, Percent_Identity=29.8360655737705, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=453, Percent_Identity=28.476821192053, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324386, Length=445, Percent_Identity=27.4157303370787, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=427, Percent_Identity=27.4004683840749, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21357415, Length=435, Percent_Identity=27.5862068965517, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI161085790, Length=459, Percent_Identity=28.322440087146, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574759, Length=460, Percent_Identity=28.2608695652174, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356575, Length=450, Percent_Identity=28.8888888888889, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 50703; Mature: 50703

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETLEKAAVALQAELNLEPFWMPFTANRQFKANPRLLVAARDMYYTSHDGRQILDGTAG
CHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCEEECCCCCCHHCCCCC
LWCVNAGHCRPPIVEAIQQQVAQLDYAPAFQMGHPKAFLLAEQLIQLTPAGLDHVFFTNS
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECC
GSEAVDTALKMAIAYHRLRGQGSRQRLIGRERGYHGVGFGGISVGGISNNRKFFGSLIPG
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHCCC
VDHLPHTHNLEQNAFSRGLPRWGSHLAEDLERIVALHDASTIAAVIVEPVAGSTGVLLPP
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHEEHHHEECCCCCCCEECCC
VGYLEKLRAICDKYGILLIFDEVITGFGRLGSPFAANYFGVVPDLICCAKGLTNGTIPMG
HHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
AVIVKQEIYSAFMEAAGSADDLHRPGDNSRTLSWSPIEFFHGYTYSGHPVASAAGLATLN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCHHHHHHHHHHH
LYREEGLFERAANLAPLWEEALHSLRGLPHVIDVRNLGLVGAIELEGIPGRPTARAFEAF
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHH
LRCYERGVLIRTTGDTIALSPPLIIEEAHIEHLIATLKRVLQELP
HHHHHCCEEEEECCCEEEECCCCEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQETLEKAAVALQAELNLEPFWMPFTANRQFKANPRLLVAARDMYYTSHDGRQILDGTAG
CHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCEEECCCCCCHHCCCCC
LWCVNAGHCRPPIVEAIQQQVAQLDYAPAFQMGHPKAFLLAEQLIQLTPAGLDHVFFTNS
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECC
GSEAVDTALKMAIAYHRLRGQGSRQRLIGRERGYHGVGFGGISVGGISNNRKFFGSLIPG
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHCCC
VDHLPHTHNLEQNAFSRGLPRWGSHLAEDLERIVALHDASTIAAVIVEPVAGSTGVLLPP
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHEEHHHEECCCCCCCEECCC
VGYLEKLRAICDKYGILLIFDEVITGFGRLGSPFAANYFGVVPDLICCAKGLTNGTIPMG
HHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
AVIVKQEIYSAFMEAAGSADDLHRPGDNSRTLSWSPIEFFHGYTYSGHPVASAAGLATLN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCHHHHHHHHHHH
LYREEGLFERAANLAPLWEEALHSLRGLPHVIDVRNLGLVGAIELEGIPGRPTARAFEAF
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHH
LRCYERGVLIRTTGDTIALSPPLIIEEAHIEHLIATLKRVLQELP
HHHHHCCEEEEECCCEEEECCCCEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]