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The map label for this gene is wecB [C]

Identifier: 86609559

GI number: 86609559

Start: 2206276

End: 2207412

Strand: Reverse

Name: wecB [C]

Synonym: CYB_2112

Alternate gene names: 86609559

Gene position: 2207412-2206276 (Counterclockwise)

Preceding gene: 86609560

Following gene: 86609558

Centisome position: 72.45

GC content: 60.95

Gene sequence:

>1137_bases
ATGGCCTCTCTTCCCCTCGTTGCCGTGATCTTGGGCACACGGCCCGAAGCCATTAAGCTGGCCCCGGTGATCCAAGCTCT
GCGTGCCAGTCCCCATCTGCGCACCGAGCTGATCTTGACCGGACAACACCGGGAAATGGTGGATCAGGTGATGCGGCTAT
TCGGTCTGCAAGCGGATCGGGATCTGGCGATCATGCGCCCCCGCCAAAGCTTGACAGACATCACCGAAGCCACCTTGCGG
GGCCTGGAACTCTACTTTCAAGAGCAACATCCTCAACTGGTTTTGGTGCAGGGAGATACCACCACCGCCTTTGCGGCTGC
CTTGGCAGCTTTCTACCACCGCATCCCGGTTGGGCATGTGGAAGCCGGACTGCGCACCGATGATCTCTACAATCCTTTCC
CCGAAGAGGCCAATCGCCGCCTGATCTCCCAGTTGGCCAGCCTGCACTTTGCCCCTACCCCCCAAGCCGTTGACAACCTG
AAGCGAAGCCACGTGGTGGGATCCATCCATTGCACCGGCAACACTGTCATCGACGCCCTACTGCAGGTGGCCTCCCAAGG
GATCCCCTGCCCCATTCCCGGGCTGGACTGGCAGCGCTACCGTGTCCTGCTGGTTACCTTGCACCGACGCGAAAATTGGG
GGGATCCCCTAACCGCCATCGGCAAGGCTCTGCTGCAGATCTTGGCCGAGTTTCCCGATACCGCCCTTCTTTTGCCCCTC
CATCCCAACCCCTTGGTGCGGGATCCCCTGCAAGCCCTGTTGGGATCCCATGAGCGGGCTTTTCTCACTGAGCCTCTGGA
CTATCCCCTCTGGGTGAGCGCCATGCAGCGCTGTACCCTCATCCTCAGCGACTCCGGCGGCATTCAAGAAGAGGCCCCTG
CCCTGGGCAAACCGGTGCTGGTGCTGCGGCAGACCACCGAACGTCCTGAAGCGATTGCTGCCGGCACCGCCCGCCTGGTA
GGCACACACCCCGAAAAGATCCTGAAGGCAGCCCGAGAATTGCTCACAGACCCACAAGCCTATGCCCGCATGGCCCAAGC
CCAAAACCCCTTTGGCGATGGCACTGCCGCCCGGCAAATTCGCCACATCATCGAGCGGTGGTTTAACCCGCAAAGCCCTC
GAGAAGAACAAAGTTAA

Upstream 100 bases:

>100_bases
GCCTCTGTTTTGTTAGTGGTTTTTGTTAGTGGTTTGTTGGTGGCCTTGCTTCAATGAGCTGCGCTTCCCATCTCCTACAG
GTGCCGATGTCCTTGAGCTT

Downstream 100 bases:

>100_bases
GAATTAAAAGTTAAGAATTAAATAAGAATCAAAGATGTATAGGCCGTTACCGGGAAAACCGTTTCTTTACCTATTGCTCT
CAATAAGACAATTAATCTCA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MASLPLVAVILGTRPEAIKLAPVIQALRASPHLRTELILTGQHREMVDQVMRLFGLQADRDLAIMRPRQSLTDITEATLR
GLELYFQEQHPQLVLVQGDTTTAFAAALAAFYHRIPVGHVEAGLRTDDLYNPFPEEANRRLISQLASLHFAPTPQAVDNL
KRSHVVGSIHCTGNTVIDALLQVASQGIPCPIPGLDWQRYRVLLVTLHRRENWGDPLTAIGKALLQILAEFPDTALLLPL
HPNPLVRDPLQALLGSHERAFLTEPLDYPLWVSAMQRCTLILSDSGGIQEEAPALGKPVLVLRQTTERPEAIAAGTARLV
GTHPEKILKAARELLTDPQAYARMAQAQNPFGDGTAARQIRHIIERWFNPQSPREEQS

Sequences:

>Translated_378_residues
MASLPLVAVILGTRPEAIKLAPVIQALRASPHLRTELILTGQHREMVDQVMRLFGLQADRDLAIMRPRQSLTDITEATLR
GLELYFQEQHPQLVLVQGDTTTAFAAALAAFYHRIPVGHVEAGLRTDDLYNPFPEEANRRLISQLASLHFAPTPQAVDNL
KRSHVVGSIHCTGNTVIDALLQVASQGIPCPIPGLDWQRYRVLLVTLHRRENWGDPLTAIGKALLQILAEFPDTALLLPL
HPNPLVRDPLQALLGSHERAFLTEPLDYPLWVSAMQRCTLILSDSGGIQEEAPALGKPVLVLRQTTERPEAIAAGTARLV
GTHPEKILKAARELLTDPQAYARMAQAQNPFGDGTAARQIRHIIERWFNPQSPREEQS
>Mature_377_residues
ASLPLVAVILGTRPEAIKLAPVIQALRASPHLRTELILTGQHREMVDQVMRLFGLQADRDLAIMRPRQSLTDITEATLRG
LELYFQEQHPQLVLVQGDTTTAFAAALAAFYHRIPVGHVEAGLRTDDLYNPFPEEANRRLISQLASLHFAPTPQAVDNLK
RSHVVGSIHCTGNTVIDALLQVASQGIPCPIPGLDWQRYRVLLVTLHRRENWGDPLTAIGKALLQILAEFPDTALLLPLH
PNPLVRDPLQALLGSHERAFLTEPLDYPLWVSAMQRCTLILSDSGGIQEEAPALGKPVLVLRQTTERPEAIAAGTARLVG
THPEKILKAARELLTDPQAYARMAQAQNPFGDGTAARQIRHIIERWFNPQSPREEQS

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=364, Percent_Identity=50, Blast_Score=321, Evalue=4e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41844; Mature: 41713

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLPLVAVILGTRPEAIKLAPVIQALRASPHLRTELILTGQHREMVDQVMRLFGLQADR
CCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCC
DLAIMRPRQSLTDITEATLRGLELYFQEQHPQLVLVQGDTTTAFAAALAAFYHRIPVGHV
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHH
EAGLRTDDLYNPFPEEANRRLISQLASLHFAPTPQAVDNLKRSHVVGSIHCTGNTVIDAL
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEECCHHHHHHH
LQVASQGIPCPIPGLDWQRYRVLLVTLHRRENWGDPLTAIGKALLQILAEFPDTALLLPL
HHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
HPNPLVRDPLQALLGSHERAFLTEPLDYPLWVSAMQRCTLILSDSGGIQEEAPALGKPVL
CCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCEE
VLRQTTERPEAIAAGTARLVGTHPEKILKAARELLTDPQAYARMAQAQNPFGDGTAARQI
EEECCCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
RHIIERWFNPQSPREEQS
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ASLPLVAVILGTRPEAIKLAPVIQALRASPHLRTELILTGQHREMVDQVMRLFGLQADR
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCC
DLAIMRPRQSLTDITEATLRGLELYFQEQHPQLVLVQGDTTTAFAAALAAFYHRIPVGHV
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHH
EAGLRTDDLYNPFPEEANRRLISQLASLHFAPTPQAVDNLKRSHVVGSIHCTGNTVIDAL
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEECCHHHHHHH
LQVASQGIPCPIPGLDWQRYRVLLVTLHRRENWGDPLTAIGKALLQILAEFPDTALLLPL
HHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
HPNPLVRDPLQALLGSHERAFLTEPLDYPLWVSAMQRCTLILSDSGGIQEEAPALGKPVL
CCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCEE
VLRQTTERPEAIAAGTARLVGTHPEKILKAARELLTDPQAYARMAQAQNPFGDGTAARQI
EEECCCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
RHIIERWFNPQSPREEQS
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]