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The map label for this gene is csd [H]

Identifier: 86609446

GI number: 86609446

Start: 2103447

End: 2104724

Strand: Reverse

Name: csd [H]

Synonym: CYB_1997

Alternate gene names: 86609446

Gene position: 2104724-2103447 (Counterclockwise)

Preceding gene: 86609450

Following gene: 86609445

Centisome position: 69.08

GC content: 57.59

Gene sequence:

>1278_bases
ATGGCGGTATCCCCCCTTTCTTCTCTCAAGCTTGACCATTCTTTCGATCTGGCTGCCCAGGTGCGGTCAGATTTTCCGAT
TTTGCAGCGCCAGGTCAACGGCCACCCGCTAATCTACTTTGACAATGCCGCCACTTCTCAAAAGCCACTGGCGGTTATGC
AGGCGATGGATCATTACTATCGACACTGCAACGCCAACGTGCATCGTGGGGTGCATACGCTGAGCAACGAAGCCACAGAT
GCCTATGAGGGGGCGCGGGAAAAGATCGCTCGGTTTGTGAACGCGCCTTCTCCTCAGGAGATCATCTACACCCGCAATGC
CAGCGAAGCCATCAATCTGGTGGCCTATAGTTGGGGCTTGAGCCATCTGGAGCGGGGGGATGAGATCGTCCTCTCGGTGA
TGGAGCACCACAGCAACCTGATCCCGTGGCAATGGGTGGCCCAGAAGACGGGAGCCCACCTCAAGTTCATCCAGATCACG
CCAGAGGGAGAGTTGGATCTGGAGCACTACCAATCTTTGCTCAGCGACCGCACCCGCTTGGTGGCGGTAACCCAGGTCTC
CAACATGCTGGGATCCATCAACCCCGTTCAGGAGATGACTGAACTGGCCCATCGTTACGGAGCCAAGGTTTTGCTGGATG
CTTGCCAGAGTGTGCCCCACATGCCTGTGGATGTCCAGGCGCTGGATTGCGATTGGTTGGCCTTTTCGGGGCACAAGATG
TGTGGCCCAACGGGGATTGGCGTCCTCTACGGCAGGCGGGAGCTGCTGCGAGCGATGCCCCCTTTTTTGGGTGGGGGAGA
GATGATCGCCGATGTGTACTGGGATCACGCCACCTATGCGGATATCCCCCACAAATTTGAAGCCGGTACGCCGGCGATTG
CCCAGGCGGTGGGGTTAGGGGCAGCCGTAGATTACTTGAGCCAGATCGGTCTGGAGCGGGTTCATGCCCATGAACAAAGG
TTGATTACCCACCTGTTGGACGGGATCCAGCACATAGCGGGTATTACGGTTTATGGCCCCAAGGATCCGGCGCGACGGGC
AGGGCTGGTTAGCTTTTCGGTGGAGGCTGTCCATCCCCATGACCTGTCTACTTTGCTGGATGAGCAAGGCATTGCCGTTC
GAGCGGGGCACCACTGCACTCAACCCCTCCATCGCTATTTGGGAGTACAATCCACTGCCCGAGCCAGTGTTTACCTGTAC
AACACGTTGGCGGAGGTGGATCGCTTTTTAGACGTGTTGGCAGAAGCGGTGGAGTTCTTCGGCGCTGCCCTAAGCTAG

Upstream 100 bases:

>100_bases
AAGGGATCCCTGGCCGTTGCAACGGTTTGGGCGGATGGGTTTGCCGAAGGCTGGCCGGAAGCGATGTCATACTGAGGGAA
GCAGGCTTTTTGCGCAGACC

Downstream 100 bases:

>100_bases
GGATCCGGGATAGACCTCTGAAGAGATGAGGTAGACTCATGCCTTGGGATCTGGGGCGGTTCTGGAACACGCTCACCTAC
TATGAGGCCCTGCCTTTGGC

Product: SufS family cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MAVSPLSSLKLDHSFDLAAQVRSDFPILQRQVNGHPLIYFDNAATSQKPLAVMQAMDHYYRHCNANVHRGVHTLSNEATD
AYEGAREKIARFVNAPSPQEIIYTRNASEAINLVAYSWGLSHLERGDEIVLSVMEHHSNLIPWQWVAQKTGAHLKFIQIT
PEGELDLEHYQSLLSDRTRLVAVTQVSNMLGSINPVQEMTELAHRYGAKVLLDACQSVPHMPVDVQALDCDWLAFSGHKM
CGPTGIGVLYGRRELLRAMPPFLGGGEMIADVYWDHATYADIPHKFEAGTPAIAQAVGLGAAVDYLSQIGLERVHAHEQR
LITHLLDGIQHIAGITVYGPKDPARRAGLVSFSVEAVHPHDLSTLLDEQGIAVRAGHHCTQPLHRYLGVQSTARASVYLY
NTLAEVDRFLDVLAEAVEFFGAALS

Sequences:

>Translated_425_residues
MAVSPLSSLKLDHSFDLAAQVRSDFPILQRQVNGHPLIYFDNAATSQKPLAVMQAMDHYYRHCNANVHRGVHTLSNEATD
AYEGAREKIARFVNAPSPQEIIYTRNASEAINLVAYSWGLSHLERGDEIVLSVMEHHSNLIPWQWVAQKTGAHLKFIQIT
PEGELDLEHYQSLLSDRTRLVAVTQVSNMLGSINPVQEMTELAHRYGAKVLLDACQSVPHMPVDVQALDCDWLAFSGHKM
CGPTGIGVLYGRRELLRAMPPFLGGGEMIADVYWDHATYADIPHKFEAGTPAIAQAVGLGAAVDYLSQIGLERVHAHEQR
LITHLLDGIQHIAGITVYGPKDPARRAGLVSFSVEAVHPHDLSTLLDEQGIAVRAGHHCTQPLHRYLGVQSTARASVYLY
NTLAEVDRFLDVLAEAVEFFGAALS
>Mature_424_residues
AVSPLSSLKLDHSFDLAAQVRSDFPILQRQVNGHPLIYFDNAATSQKPLAVMQAMDHYYRHCNANVHRGVHTLSNEATDA
YEGAREKIARFVNAPSPQEIIYTRNASEAINLVAYSWGLSHLERGDEIVLSVMEHHSNLIPWQWVAQKTGAHLKFIQITP
EGELDLEHYQSLLSDRTRLVAVTQVSNMLGSINPVQEMTELAHRYGAKVLLDACQSVPHMPVDVQALDCDWLAFSGHKMC
GPTGIGVLYGRRELLRAMPPFLGGGEMIADVYWDHATYADIPHKFEAGTPAIAQAVGLGAAVDYLSQIGLERVHAHEQRL
ITHLLDGIQHIAGITVYGPKDPARRAGLVSFSVEAVHPHDLSTLLDEQGIAVRAGHHCTQPLHRYLGVQSTARASVYLYN
TLAEVDRFLDVLAEAVEFFGAALS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=384, Percent_Identity=26.3020833333333, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI156713448, Length=301, Percent_Identity=25.9136212624585, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=47.8908188585608, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1789175, Length=402, Percent_Identity=41.2935323383085, Blast_Score=313, Evalue=9e-87,
Organism=Escherichia coli, GI48994898, Length=402, Percent_Identity=26.865671641791, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=349, Percent_Identity=26.647564469914, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193211090, Length=389, Percent_Identity=25.706940874036, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319831, Length=395, Percent_Identity=27.3417721518987, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20129463, Length=414, Percent_Identity=27.7777777777778, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46894; Mature: 46763

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSPLSSLKLDHSFDLAAQVRSDFPILQRQVNGHPLIYFDNAATSQKPLAVMQAMDHYY
CCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHH
RHCNANVHRGVHTLSNEATDAYEGAREKIARFVNAPSPQEIIYTRNASEAINLVAYSWGL
HHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCH
SHLERGDEIVLSVMEHHSNLIPWQWVAQKTGAHLKFIQITPEGELDLEHYQSLLSDRTRL
HHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCHHE
VAVTQVSNMLGSINPVQEMTELAHRYGAKVLLDACQSVPHMPVDVQALDCDWLAFSGHKM
EHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCC
CGPTGIGVLYGRRELLRAMPPFLGGGEMIADVYWDHATYADIPHKFEAGTPAIAQAVGLG
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
AAVDYLSQIGLERVHAHEQRLITHLLDGIQHIAGITVYGPKDPARRAGLVSFSVEAVHPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCEEEEEEEEECCC
DLSTLLDEQGIAVRAGHHCTQPLHRYLGVQSTARASVYLYNTLAEVDRFLDVLAEAVEFF
HHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHH
GAALS
HHCCC
>Mature Secondary Structure 
AVSPLSSLKLDHSFDLAAQVRSDFPILQRQVNGHPLIYFDNAATSQKPLAVMQAMDHYY
CCCCCHHHCCCCCHHHHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHH
RHCNANVHRGVHTLSNEATDAYEGAREKIARFVNAPSPQEIIYTRNASEAINLVAYSWGL
HHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCH
SHLERGDEIVLSVMEHHSNLIPWQWVAQKTGAHLKFIQITPEGELDLEHYQSLLSDRTRL
HHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCHHE
VAVTQVSNMLGSINPVQEMTELAHRYGAKVLLDACQSVPHMPVDVQALDCDWLAFSGHKM
EHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCC
CGPTGIGVLYGRRELLRAMPPFLGGGEMIADVYWDHATYADIPHKFEAGTPAIAQAVGLG
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
AAVDYLSQIGLERVHAHEQRLITHLLDGIQHIAGITVYGPKDPARRAGLVSFSVEAVHPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCEEEEEEEEECCC
DLSTLLDEQGIAVRAGHHCTQPLHRYLGVQSTARASVYLYNTLAEVDRFLDVLAEAVEFF
HHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHH
GAALS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]