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The map label for this gene is fbp [H]

Identifier: 86609435

GI number: 86609435

Start: 2087652

End: 2088650

Strand: Reverse

Name: fbp [H]

Synonym: CYB_1986

Alternate gene names: 86609435

Gene position: 2088650-2087652 (Counterclockwise)

Preceding gene: 86609437

Following gene: 86609434

Centisome position: 68.55

GC content: 60.06

Gene sequence:

>999_bases
ATGTTGCGGGATGTGCTCACCCTCTCCCGTCATGTTTTACAGCAGTTTGGCAGTTTTACGGCAGAGGCCCAAGACTTCAG
CGCCCTGATGAACCGCATTGCCCTGGCCGGCAAGATGATCGCCCGGCGGCTGAGTCAGGCAGGACTGATCGAAGGGGCGC
TGGGGGTTACCGGCAGCCTCAATGTCCAAGGGGAAGAACAGCAACAGATGGATGACTATGCCAACCGGGCCTTCATTCGC
GCTTTGGAGCAAACGGGCCTGGTGTGTCGGCTGGTCTCGGAAGAGATGAAAACCCCGGCTCGCCTGCCGGAAAACTGCTC
CCTCAGCCGCCTGGCCCTGATGATCGATCCCCTGGATGGATCCTCCAACATTGACGCCAACCTCAGCGTCGGCTCTATCT
TCTCCGTCCTTCACCCTCTTGAGGATCGCCCGGAAGCGGACAACCAAGACCTGCTGCAACCGGGCCGTCGCCAACTGGCT
GCAGGATATATTCTCTACGGCCCCAGCACCCAATTGGTCTATTCCGTCGGCAAGGGGGTACACGGTTTTACGTTGGATCC
CAGCTTGGGGGAATTTATCCTCTCCCGCAGCGACATCCGCATTCCTGAACGCGGCTCCGTCTACAGCCTCAACGAGGGCT
ATTTTTGCCAGTGGAGCGAAGGGATCCAGAACTATGTCCGGTATGTTCACCGCCGCGATGGCTACATCTCCCGTTACAGC
GGCGCTCTGGTGGCGGATTTTCACCGCATTCTCCTGCAGGGCGGAGTTTACCTCTATCCCGGCACCCAGAAAAAACCGGA
GGGCAAGCTGCGCCTGATGTACGAGGCCAACCCCCTGGCTTTTCTGGCCGAGCAGGCGGGCGGGGCGGCCACCACTGGCA
CCGAGGCCATCCTAGACATCGTCCCCCAATCTCTCCACCAACGGGTGCCCCTTATCATCGGCAGCCGCGAGAACGTGGAA
GAAGTGCTGCGCTGCCTAGAGGGTTCTCTGGTGCCCTAG

Upstream 100 bases:

>100_bases
CGTGTTGGCGAAGCCTCGTATGGTTCTCAGCTCTCCTCTCCCCTCGCCTGCAGTGCCCAGCAGTGCCGACCGCGTTAGCG
GGACGGAGTCCTCACGGGAG

Downstream 100 bases:

>100_bases
GTTCTTCCCAATCCTTCTCTTTGAGCCAAGCTGGCCTATGGTAACCCTGGCAGAAAACCCCCTTCGCGTTGGTCTCAACC
AAGAACGCACCCCGGATCCC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLRDVLTLSRHVLQQFGSFTAEAQDFSALMNRIALAGKMIARRLSQAGLIEGALGVTGSLNVQGEEQQQMDDYANRAFIR
ALEQTGLVCRLVSEEMKTPARLPENCSLSRLALMIDPLDGSSNIDANLSVGSIFSVLHPLEDRPEADNQDLLQPGRRQLA
AGYILYGPSTQLVYSVGKGVHGFTLDPSLGEFILSRSDIRIPERGSVYSLNEGYFCQWSEGIQNYVRYVHRRDGYISRYS
GALVADFHRILLQGGVYLYPGTQKKPEGKLRLMYEANPLAFLAEQAGGAATTGTEAILDIVPQSLHQRVPLIIGSRENVE
EVLRCLEGSLVP

Sequences:

>Translated_332_residues
MLRDVLTLSRHVLQQFGSFTAEAQDFSALMNRIALAGKMIARRLSQAGLIEGALGVTGSLNVQGEEQQQMDDYANRAFIR
ALEQTGLVCRLVSEEMKTPARLPENCSLSRLALMIDPLDGSSNIDANLSVGSIFSVLHPLEDRPEADNQDLLQPGRRQLA
AGYILYGPSTQLVYSVGKGVHGFTLDPSLGEFILSRSDIRIPERGSVYSLNEGYFCQWSEGIQNYVRYVHRRDGYISRYS
GALVADFHRILLQGGVYLYPGTQKKPEGKLRLMYEANPLAFLAEQAGGAATTGTEAILDIVPQSLHQRVPLIIGSRENVE
EVLRCLEGSLVP
>Mature_332_residues
MLRDVLTLSRHVLQQFGSFTAEAQDFSALMNRIALAGKMIARRLSQAGLIEGALGVTGSLNVQGEEQQQMDDYANRAFIR
ALEQTGLVCRLVSEEMKTPARLPENCSLSRLALMIDPLDGSSNIDANLSVGSIFSVLHPLEDRPEADNQDLLQPGRRQLA
AGYILYGPSTQLVYSVGKGVHGFTLDPSLGEFILSRSDIRIPERGSVYSLNEGYFCQWSEGIQNYVRYVHRRDGYISRYS
GALVADFHRILLQGGVYLYPGTQKKPEGKLRLMYEANPLAFLAEQAGGAATTGTEAILDIVPQSLHQRVPLIIGSRENVE
EVLRCLEGSLVP

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=329, Percent_Identity=44.0729483282675, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI189083692, Length=328, Percent_Identity=42.6829268292683, Blast_Score=244, Evalue=7e-65,
Organism=Homo sapiens, GI16579888, Length=328, Percent_Identity=42.6829268292683, Blast_Score=244, Evalue=7e-65,
Organism=Escherichia coli, GI1790679, Length=324, Percent_Identity=46.2962962962963, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17508131, Length=327, Percent_Identity=45.565749235474, Blast_Score=284, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6323409, Length=327, Percent_Identity=39.1437308868502, Blast_Score=244, Evalue=1e-65,
Organism=Drosophila melanogaster, GI45550998, Length=329, Percent_Identity=42.8571428571429, Blast_Score=270, Evalue=7e-73,
Organism=Drosophila melanogaster, GI19921562, Length=329, Percent_Identity=42.8571428571429, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36557; Mature: 36557

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRDVLTLSRHVLQQFGSFTAEAQDFSALMNRIALAGKMIARRLSQAGLIEGALGVTGSL
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEE
NVQGEEQQQMDDYANRAFIRALEQTGLVCRLVSEEMKTPARLPENCSLSRLALMIDPLDG
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
SSNIDANLSVGSIFSVLHPLEDRPEADNQDLLQPGRRQLAAGYILYGPSTQLVYSVGKGV
CCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCC
HGFTLDPSLGEFILSRSDIRIPERGSVYSLNEGYFCQWSEGIQNYVRYVHRRDGYISRYS
CCEEECCHHHHHHHCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHCCCCHHHHC
GALVADFHRILLQGGVYLYPGTQKKPEGKLRLMYEANPLAFLAEQAGGAATTGTEAILDI
CHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCHHHHHHHH
VPQSLHQRVPLIIGSRENVEEVLRCLEGSLVP
HHHHHHCCCCEEECCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MLRDVLTLSRHVLQQFGSFTAEAQDFSALMNRIALAGKMIARRLSQAGLIEGALGVTGSL
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEE
NVQGEEQQQMDDYANRAFIRALEQTGLVCRLVSEEMKTPARLPENCSLSRLALMIDPLDG
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
SSNIDANLSVGSIFSVLHPLEDRPEADNQDLLQPGRRQLAAGYILYGPSTQLVYSVGKGV
CCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCC
HGFTLDPSLGEFILSRSDIRIPERGSVYSLNEGYFCQWSEGIQNYVRYVHRRDGYISRYS
CCEEECCHHHHHHHCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHCCCCHHHHC
GALVADFHRILLQGGVYLYPGTQKKPEGKLRLMYEANPLAFLAEQAGGAATTGTEAILDI
CHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCHHHHHHHH
VPQSLHQRVPLIIGSRENVEEVLRCLEGSLVP
HHHHHHCCCCEEECCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA