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The map label for this gene is nrdR

Identifier: 86609406

GI number: 86609406

Start: 2045913

End: 2046455

Strand: Direct

Name: nrdR

Synonym: CYB_1950

Alternate gene names: 86609406

Gene position: 2045913-2046455 (Clockwise)

Preceding gene: 86609405

Following gene: 86609407

Centisome position: 67.15

GC content: 54.7

Gene sequence:

>543_bases
ATGAAATGTCCCCGCTGCAGCAAACAAGAAATCCGAGTTTTGGAATCTCGTTCGGCAGAAGGTGGCCAGAGTGTGCGGCG
GCGGCGAGAATGCATGTCCTGTGGCTACCGCTTCACCACCTATGAGCGCATCGAGTTCATGCCCATCATGGTCATTAAAC
GGGATGGATCCCGCGAAAGTTTCAACCGCAACAAGATCCTGCAAGGGGTGATGCGTGCCTGCCAAAAAACCCCCGTCACC
GTCAGACAGATGGAAGAGCTGGTCAATGAGATCGAAGAAAAACTGCAATTGGAAGATGCCCAAGAGGTAACCAGCCTGCG
CATCGGCGAGATGGTGCTGGAGCGCCTGCAACACCTAAGCGAGGTGGCCTACGTGCGCTTTGCCTCCGTTTATCGCCAGT
TTCAGGGTATAAAAGACTTTGTCAATGAGCTGGAACAGTTGGAACCACCTCTGCGACGGGATCTGGAGCGGCTGCTGCAG
GACTCCTCTGCCTCAGATTCCGAATCTTCAGGCTCCCCGGACTTGGTGGGAGAGTATTCGTGA

Upstream 100 bases:

>100_bases
TCCATCTCATTTGCAATCTGTCTAAGCACCAGAAGATTAAGCATCCGGTAAAATTGAGGCACCCTCCTACCCACCTGTCG
CTTTGTAAGGACTGCAAGCC

Downstream 100 bases:

>100_bases
CGTGGGAACGACAGCGCAAGCCGGCCCTCCCTGGAAGCAGCGGGGAAATGGCGCTTGTGGGCGGGAAAAATTGCTGTGAA
GAGATCGCCCATTCCAAAGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKCPRCSKQEIRVLESRSAEGGQSVRRRRECMSCGYRFTTYERIEFMPIMVIKRDGSRESFNRNKILQGVMRACQKTPVT
VRQMEELVNEIEEKLQLEDAQEVTSLRIGEMVLERLQHLSEVAYVRFASVYRQFQGIKDFVNELEQLEPPLRRDLERLLQ
DSSASDSESSGSPDLVGEYS

Sequences:

>Translated_180_residues
MKCPRCSKQEIRVLESRSAEGGQSVRRRRECMSCGYRFTTYERIEFMPIMVIKRDGSRESFNRNKILQGVMRACQKTPVT
VRQMEELVNEIEEKLQLEDAQEVTSLRIGEMVLERLQHLSEVAYVRFASVYRQFQGIKDFVNELEQLEPPLRRDLERLLQ
DSSASDSESSGSPDLVGEYS
>Mature_180_residues
MKCPRCSKQEIRVLESRSAEGGQSVRRRRECMSCGYRFTTYERIEFMPIMVIKRDGSRESFNRNKILQGVMRACQKTPVT
VRQMEELVNEIEEKLQLEDAQEVTSLRIGEMVLERLQHLSEVAYVRFASVYRQFQGIKDFVNELEQLEPPLRRDLERLLQ
DSSASDSESSGSPDLVGEYS

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=43.9189189189189, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_SYNJB (Q2JK90)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_478168.1
- STRING:   Q2JK90
- GeneID:   3900173
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1950
- TIGR:   CYB_1950
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q2JK90
- ProtClustDB:   PRK00464
- BioCyc:   SSP321332:CYB_1950-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 20934; Mature: 20934

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPRCSKQEIRVLESRSAEGGQSVRRRRECMSCGYRFTTYERIEFMPIMVIKRDGSRES
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCH
FNRNKILQGVMRACQKTPVTVRQMEELVNEIEEKLQLEDAQEVTSLRIGEMVLERLQHLS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFQGIKDFVNELEQLEPPLRRDLERLLQDSSASDSESSGSPDLVGEYS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKCPRCSKQEIRVLESRSAEGGQSVRRRRECMSCGYRFTTYERIEFMPIMVIKRDGSRES
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCH
FNRNKILQGVMRACQKTPVTVRQMEELVNEIEEKLQLEDAQEVTSLRIGEMVLERLQHLS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFQGIKDFVNELEQLEPPLRRDLERLLQDSSASDSESSGSPDLVGEYS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA