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The map label for this gene is sasA

Identifier: 86609351

GI number: 86609351

Start: 1981377

End: 1982510

Strand: Reverse

Name: sasA

Synonym: CYB_1895

Alternate gene names: 86609351

Gene position: 1982510-1981377 (Counterclockwise)

Preceding gene: 86609352

Following gene: 86609350

Centisome position: 65.07

GC content: 61.11

Gene sequence:

>1134_bases
ATGCAAACTTCGCCAGACCTCACCTCCGCTCGTTCTGTCATTCGCCTGCTGCTGTTCGCCAAGAGTCGAGCTGTTGTTGC
CGAGCTTGAGGAGCATCTGCGCCAGCACATCCAGGGGTTGCCCGGCCAATACCCTGCCCAACTGGAAGTGGTGCCGCTGG
AGGAGCACCCCTACCTGGCAGAGCATTACAAGCTGGTGGCCACTCCGGCTCTGGTCAAGGCTGAGCCCTTGCCCGCTCAA
GTTTTGGCGGGCGCAGACTTGGCGACGCAGTTGGAAGTGTGGTGGCCTCGTTGGCAAGGCCAAGCGGCTTTGGCCGCCCA
TCAAGAAGGAGCAGGACGGGATCCCGCCTCCCCTCCGACCACCGAGGCACTGTTGCAAATGTCGGAAGAGGTGTTTTTGC
TGCGGCAGGAGCGGGCCCAATTGCGGGAGCAGTTGGACTTCAAAGATCGCGTTCTGGCCATGCTGGTGCATGATTTGCGC
AGTCCCCTGACGGCCACGGCTCTGGCGGTCGAAACCCTGCAGCAGGGGCGCGAGGGATCCCTGGACAAAGCGCTAGAGCG
GCAGTTGTTCGACCATGCCCGCCAGCAACTGCGCAAGATGGACAGCATGATCACCGATATCCTGGAGTCGGCCCGTGGCG
CTGCCTCGGAGCTGAGGATTCGAGCCGTAGAAACCCAGTTGCCCGGCTTGTGTCAGGCGGTGATCGAGGAGCTATGGCCG
CGCATTCAAGGCAAGCGGCTGCAGTTTCAAGCGGATATTCCCGTGGATCTGCCCTCTGTTCACGTGGATCCCGACAAGAT
CCGCCAAGTTCTGTTCAACCTGCTGGACAACGCCATCAAGTACACCCCCGCCGGGGGATCCATCCGCCTCGATGTCCTCC
ATCGCACCAGCCAAAAGGTGCAGGTGACCGTCAGCGATACTGGCCCTGGGATCCCGGAAGCCGACCAAGAGAGCATCTTC
TCCGATTCCGTCCGTCTGTCCCGGGATCAACAGCAGGAGGGCTATGGCATCGGCCTTTCCCTCTGCCGACGGATCGTGCG
CGCTCACTACGGCCAGATTTGGGTGGAGTCTTCCTTGGGCAAAGGCAGCAGCTTTCATTTCACTTTGCCCGTGTATCGGC
TCTGCAAGCGCTAG

Upstream 100 bases:

>100_bases
ACGGCAATCCCGGCTGCTGAAACGCCAACCTTTGGCTTTAATGCTACGCAATGTGCTACGCACCGCTATCGCGAGCGCTA
ACGCGACTGGACTTTGGCCT

Downstream 100 bases:

>100_bases
CCGGGAGCTGGCTCCCCATGGGTGTGAGCCCCCTCAGAGAGAACAGATCTGACGGTTTTCCTGGACTTGGCAAAAGCGCT
CCGCGCCGCTTCCGCGACTA

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MQTSPDLTSARSVIRLLLFAKSRAVVAELEEHLRQHIQGLPGQYPAQLEVVPLEEHPYLAEHYKLVATPALVKAEPLPAQ
VLAGADLATQLEVWWPRWQGQAALAAHQEGAGRDPASPPTTEALLQMSEEVFLLRQERAQLREQLDFKDRVLAMLVHDLR
SPLTATALAVETLQQGREGSLDKALERQLFDHARQQLRKMDSMITDILESARGAASELRIRAVETQLPGLCQAVIEELWP
RIQGKRLQFQADIPVDLPSVHVDPDKIRQVLFNLLDNAIKYTPAGGSIRLDVLHRTSQKVQVTVSDTGPGIPEADQESIF
SDSVRLSRDQQQEGYGIGLSLCRRIVRAHYGQIWVESSLGKGSSFHFTLPVYRLCKR

Sequences:

>Translated_377_residues
MQTSPDLTSARSVIRLLLFAKSRAVVAELEEHLRQHIQGLPGQYPAQLEVVPLEEHPYLAEHYKLVATPALVKAEPLPAQ
VLAGADLATQLEVWWPRWQGQAALAAHQEGAGRDPASPPTTEALLQMSEEVFLLRQERAQLREQLDFKDRVLAMLVHDLR
SPLTATALAVETLQQGREGSLDKALERQLFDHARQQLRKMDSMITDILESARGAASELRIRAVETQLPGLCQAVIEELWP
RIQGKRLQFQADIPVDLPSVHVDPDKIRQVLFNLLDNAIKYTPAGGSIRLDVLHRTSQKVQVTVSDTGPGIPEADQESIF
SDSVRLSRDQQQEGYGIGLSLCRRIVRAHYGQIWVESSLGKGSSFHFTLPVYRLCKR
>Mature_377_residues
MQTSPDLTSARSVIRLLLFAKSRAVVAELEEHLRQHIQGLPGQYPAQLEVVPLEEHPYLAEHYKLVATPALVKAEPLPAQ
VLAGADLATQLEVWWPRWQGQAALAAHQEGAGRDPASPPTTEALLQMSEEVFLLRQERAQLREQLDFKDRVLAMLVHDLR
SPLTATALAVETLQQGREGSLDKALERQLFDHARQQLRKMDSMITDILESARGAASELRIRAVETQLPGLCQAVIEELWP
RIQGKRLQFQADIPVDLPSVHVDPDKIRQVLFNLLDNAIKYTPAGGSIRLDVLHRTSQKVQVTVSDTGPGIPEADQESIF
SDSVRLSRDQQQEGYGIGLSLCRRIVRAHYGQIWVESSLGKGSSFHFTLPVYRLCKR

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=31.4516129032258, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=30.2040816326531, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=281, Percent_Identity=28.1138790035587, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=25.6521739130435, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.25, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=25.0909090909091, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=27.1966527196653, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=30.5343511450382, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=230, Percent_Identity=30, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=26.8, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994928, Length=131, Percent_Identity=33.587786259542, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=127, Percent_Identity=34.6456692913386, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=24.2290748898678, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=91, Percent_Identity=39.5604395604396, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SASA_SYNJB (Q2JKD9)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_478113.1
- ProteinModelPortal:   Q2JKD9
- STRING:   Q2JKD9
- GeneID:   3900838
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1895
- TIGR:   CYB_1895
- eggNOG:   COG0642
- HOGENOM:   HBG284956
- OMA:   IYSEAPL
- PhylomeDB:   Q2JKD9
- ProtClustDB:   PRK09303
- BioCyc:   SSP321332:CYB_1895-MONOMER
- GO:   GO:0016020
- HAMAP:   MF_01837
- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.30.565.10
- Gene3D:   G3DSA:3.40.30.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim; SSF52833 Thiordxn-like_fd

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42161; Mature: 42161

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSPDLTSARSVIRLLLFAKSRAVVAELEEHLRQHIQGLPGQYPAQLEVVPLEEHPYLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHH
EHYKLVATPALVKAEPLPAQVLAGADLATQLEVWWPRWQGQAALAAHQEGAGRDPASPPT
HHHHHHCCCHHHCCCCCCHHHHCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCH
TEALLQMSEEVFLLRQERAQLREQLDFKDRVLAMLVHDLRSPLTATALAVETLQQGREGS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
LDKALERQLFDHARQQLRKMDSMITDILESARGAASELRIRAVETQLPGLCQAVIEELWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RIQGKRLQFQADIPVDLPSVHVDPDKIRQVLFNLLDNAIKYTPAGGSIRLDVLHRTSQKV
HCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCEE
QVTVSDTGPGIPEADQESIFSDSVRLSRDQQQEGYGIGLSLCRRIVRAHYGQIWVESSLG
EEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCC
KGSSFHFTLPVYRLCKR
CCCCEEEECHHHHHHCC
>Mature Secondary Structure
MQTSPDLTSARSVIRLLLFAKSRAVVAELEEHLRQHIQGLPGQYPAQLEVVPLEEHPYLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHH
EHYKLVATPALVKAEPLPAQVLAGADLATQLEVWWPRWQGQAALAAHQEGAGRDPASPPT
HHHHHHCCCHHHCCCCCCHHHHCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCH
TEALLQMSEEVFLLRQERAQLREQLDFKDRVLAMLVHDLRSPLTATALAVETLQQGREGS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
LDKALERQLFDHARQQLRKMDSMITDILESARGAASELRIRAVETQLPGLCQAVIEELWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RIQGKRLQFQADIPVDLPSVHVDPDKIRQVLFNLLDNAIKYTPAGGSIRLDVLHRTSQKV
HCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCEE
QVTVSDTGPGIPEADQESIFSDSVRLSRDQQQEGYGIGLSLCRRIVRAHYGQIWVESSLG
EEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCC
KGSSFHFTLPVYRLCKR
CCCCEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA