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The map label for this gene is ribD [H]

Identifier: 86609303

GI number: 86609303

Start: 1932557

End: 1933669

Strand: Direct

Name: ribD [H]

Synonym: CYB_1847

Alternate gene names: 86609303

Gene position: 1932557-1933669 (Clockwise)

Preceding gene: 86609302

Following gene: 86609304

Centisome position: 63.43

GC content: 63.79

Gene sequence:

>1113_bases
ATGATTTCGGATCAGCAGTGGATGGAACGGTGTCTATCCCTGGCCCGTTCCACACCTCAGCGTCCCTCTCCCAATCCGCG
GGTGAGTTGCGTGATCGTGCAGGGGGATCGGGTGGTGGGGGAAGGCGTTCATCCGGGGGCAGGGCAGCCCCATGCGGAGG
TGTTGGCTCTGCAACAGGCGGGATCCCTGGCCAGAGGGGCAACGCTCTACGTCAACCTGGAGCCCTGCAACCACTATGGG
CGCACTCCCCCTTGTACCGAGGCCATCCTAGCTGCCGGGATCCGGCGGGTGGTGGTGGGGATGCAGGATCCCAATCCCTT
GGTGGCCGGCAAAGGGATCCGACGCCTGCAGGAGGCGGGGATCGACGTGACGGTGGGAGTGCTGGAGCGGGAGTGCCAGG
AGCTGAACGAGGGGTTTGCCTTCGCCATTGTGCGGCAACAGTGTTTCGGCCTGCTGAAATACGCCATGACCCTGGATGGC
AAGAGCGCCGCCGCCACCGGCCACAGCCGCTGGATCAGCAACTCTCCGGCGCGGCAGTGGGTACACCAACAGCGGGCCTG
GCATGATGCCGTCATCGTTGGATCCCGAACCGTTTGGCAGGATAACCCGCGCCTCACCTGTCGCCTGGCGGAGTTGCAGG
GATCCCAGCCGTTGCGGGTGGTCCTCAGCCGTTCCCTGAACCTACCTCCCGTCGCCCATCTGTGGCAGGTGGAAGAAGCG
CCGACGTTGGTGATCACAGAAGCTGTGGCAACCCATCCTTTGTGGGGATCCCTGGCCAAGCAGGGGGTGGAGCTGCTGCA
TCTGCCCCAAGTAACCCCCTCGCGGGCGGCACAGGTGCTCTTTCAGCGGGGGTGTCTGAGTGCCCTCTGGGAATGCGGGG
GCACGCTGGCCTGGGCAGCCCTCAAAGATGGGGCGATCCAGAAAGTAGCCGCCTTCATCGCTCCCAAGATCCTAGGCGGA
GCCGCTGCGCCAACCCCGGTAGCAGGGGAGGGGATCCCTGATGTAAACCAGAGCTGGCAACTGGTGGAGCCCCGGCTGGA
GACCTTGGGGGATAACTGGTTGATCATCGGAAAGATCTCCTCTTCAGTTGGCCACAGTAGCCTACTAAAGTGA

Upstream 100 bases:

>100_bases
TGCAGGTGGCAGAGCTAGAATCCAAGGCAATTGCAGCTTTCAACCGCAAGTTGGCAGCCTTGTCACCGGCTTGAGCCGCT
CTGGAGCGGATGCCCATTTT

Downstream 100 bases:

>100_bases
CCAGCTTTCGATTGCCATACAGGGAGCTTCAGGTTTCTGAACGAACAGGCTGATATCTGTTCAATGTAAATGGATATACT
CATCAGAAAAACACAACATT

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MISDQQWMERCLSLARSTPQRPSPNPRVSCVIVQGDRVVGEGVHPGAGQPHAEVLALQQAGSLARGATLYVNLEPCNHYG
RTPPCTEAILAAGIRRVVVGMQDPNPLVAGKGIRRLQEAGIDVTVGVLERECQELNEGFAFAIVRQQCFGLLKYAMTLDG
KSAAATGHSRWISNSPARQWVHQQRAWHDAVIVGSRTVWQDNPRLTCRLAELQGSQPLRVVLSRSLNLPPVAHLWQVEEA
PTLVITEAVATHPLWGSLAKQGVELLHLPQVTPSRAAQVLFQRGCLSALWECGGTLAWAALKDGAIQKVAAFIAPKILGG
AAAPTPVAGEGIPDVNQSWQLVEPRLETLGDNWLIIGKISSSVGHSSLLK

Sequences:

>Translated_370_residues
MISDQQWMERCLSLARSTPQRPSPNPRVSCVIVQGDRVVGEGVHPGAGQPHAEVLALQQAGSLARGATLYVNLEPCNHYG
RTPPCTEAILAAGIRRVVVGMQDPNPLVAGKGIRRLQEAGIDVTVGVLERECQELNEGFAFAIVRQQCFGLLKYAMTLDG
KSAAATGHSRWISNSPARQWVHQQRAWHDAVIVGSRTVWQDNPRLTCRLAELQGSQPLRVVLSRSLNLPPVAHLWQVEEA
PTLVITEAVATHPLWGSLAKQGVELLHLPQVTPSRAAQVLFQRGCLSALWECGGTLAWAALKDGAIQKVAAFIAPKILGG
AAAPTPVAGEGIPDVNQSWQLVEPRLETLGDNWLIIGKISSSVGHSSLLK
>Mature_370_residues
MISDQQWMERCLSLARSTPQRPSPNPRVSCVIVQGDRVVGEGVHPGAGQPHAEVLALQQAGSLARGATLYVNLEPCNHYG
RTPPCTEAILAAGIRRVVVGMQDPNPLVAGKGIRRLQEAGIDVTVGVLERECQELNEGFAFAIVRQQCFGLLKYAMTLDG
KSAAATGHSRWISNSPARQWVHQQRAWHDAVIVGSRTVWQDNPRLTCRLAELQGSQPLRVVLSRSLNLPPVAHLWQVEEA
PTLVITEAVATHPLWGSLAKQGVELLHLPQVTPSRAAQVLFQRGCLSALWECGGTLAWAALKDGAIQKVAAFIAPKILGG
AAAPTPVAGEGIPDVNQSWQLVEPRLETLGDNWLIIGKISSSVGHSSLLK

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=336, Percent_Identity=40.1785714285714, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI145693172, Length=160, Percent_Identity=35, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39874; Mature: 39874

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISDQQWMERCLSLARSTPQRPSPNPRVSCVIVQGDRVVGEGVHPGAGQPHAEVLALQQA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHH
GSLARGATLYVNLEPCNHYGRTPPCTEAILAAGIRRVVVGMQDPNPLVAGKGIRRLQEAG
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHCC
IDVTVGVLERECQELNEGFAFAIVRQQCFGLLKYAMTLDGKSAAATGHSRWISNSPARQW
CCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHH
VHQQRAWHDAVIVGSRTVWQDNPRLTCRLAELQGSQPLRVVLSRSLNLPPVAHLWQVEEA
HHHHHHHHCEEEECCCEEECCCCCEEEEEECCCCCCHHHHHHHCCCCCCCHHHHHHHCCC
PTLVITEAVATHPLWGSLAKQGVELLHLPQVTPSRAAQVLFQRGCLSALWECGGTLAWAA
CEEEEEHHHHCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHH
LKDGAIQKVAAFIAPKILGGAAAPTPVAGEGIPDVNQSWQLVEPRLETLGDNWLIIGKIS
HCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHCCCCEEEEEECC
SSVGHSSLLK
CCCCHHHHCC
>Mature Secondary Structure
MISDQQWMERCLSLARSTPQRPSPNPRVSCVIVQGDRVVGEGVHPGAGQPHAEVLALQQA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHH
GSLARGATLYVNLEPCNHYGRTPPCTEAILAAGIRRVVVGMQDPNPLVAGKGIRRLQEAG
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHCC
IDVTVGVLERECQELNEGFAFAIVRQQCFGLLKYAMTLDGKSAAATGHSRWISNSPARQW
CCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHH
VHQQRAWHDAVIVGSRTVWQDNPRLTCRLAELQGSQPLRVVLSRSLNLPPVAHLWQVEEA
HHHHHHHHCEEEECCCEEECCCCCEEEEEECCCCCCHHHHHHHCCCCCCCHHHHHHHCCC
PTLVITEAVATHPLWGSLAKQGVELLHLPQVTPSRAAQVLFQRGCLSALWECGGTLAWAA
CEEEEEHHHHCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHH
LKDGAIQKVAAFIAPKILGGAAAPTPVAGEGIPDVNQSWQLVEPRLETLGDNWLIIGKIS
HCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHCCCCEEEEEECC
SSVGHSSLLK
CCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]