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The map label for this gene is argG [H]

Identifier: 86609210

GI number: 86609210

Start: 1835742

End: 1836944

Strand: Reverse

Name: argG [H]

Synonym: CYB_1752

Alternate gene names: 86609210

Gene position: 1836944-1835742 (Counterclockwise)

Preceding gene: 86609213

Following gene: 86609208

Centisome position: 60.29

GC content: 62.59

Gene sequence:

>1203_bases
ATGGGACGGGCAAAGAAGGTGGTATTGGCCTATTCAGGCGGGGTGGATACTTCCGTCTGCATTCCCTATCTCAAGCACGA
GTGGGGGGTGGAATCGGTGGTGGCCCTGGCAGTCGACTTGGGGCAGGGGGCGGAGCTGGAGGCCATTCAGGCCAAAGCCC
TTAGGGCGGGGGCAGAGCAATCTCTGGTGCGGGAGGCTGTCCAGGCCCTCATTACCGACTATGCCTTCCCGGCCATCCAG
GCCAACGCCCTCTACGAGCAGCGCTACCCCCTTTCCACGGCCCTGGCCCGACCCCTGATTGCCAAGCTGCTGGTGGAAGT
GGCGGAAGAGGTGGGCGCCGATGCGGTGGCCCACGGCTGCACCGGCAAAGGCAACGACCAGGTGCGCTTTGATCTGGCTA
TTGCTGCTTTAAATCCCCAGCTCAAAGTGTTGGCCCCTGCCCGCGAGTGGGGGATGACCCGCGAGGAGACCATTGCCTAT
GGGGAGCGCTACGGGATCCCCATGCCCGTGCAGAAGTCCAGCCCCTACAGCATCGACCTCAACATTTTGGGCCGCAGCGC
TGAAGCCGGCATCCTAGAAGATGCCGACCGGGAGCCGCCGGAGGAAGTGTATGCCCTCACCCGGCCTATTTCCCAGACAC
CCGACGAGCCCGCCTACGTGGAGATTGAGTTCGAGCAAGGGATCCCTGTCGGGCTGGATGGGCAGCGCCTTGGCCCCAAA
GCCCTCTTCGAGCAGCTCAACTCCTTAGCTGGCCTGCATGGGGTGGGCCGCATCGACATGATTGAAAACCGCCTGGTGGG
GATCAAGTCGCGGGAGATCTACGAGTGCCCTGCTCTAATGGTCTTGATCCAAGCCCACCGCGAGCTGGAAAGCCTCACCC
TCACCCGCGATGTCATCCATTACAAGTACGGCATCGAGACCACCTACAGCCAGTTGATCTACAACGGCCTTTGGTACTCG
CCGCTGCGGGAGGCTCTGGACGCCTTTATCCGCGCCACCCAGAAAAGCGTCACCGGTGTCGTGCGGATGCGGTTGCACAA
GGGCCAGGCAGTCTGTGTGGGTCGTCGCTCTCCCTACTCTCTTTACAACCCAGAGCTGGCCACCTACGGGGAAGGGGATC
AATTCGACCACCGCGCCGCCGAAGGCTTTATCTACATCTGGGGCCTGCCCACCCGTGTCTGGGCCCAGGTGCACCGGGGC
TAG

Upstream 100 bases:

>100_bases
CCCTTGAGAATAGCTGAGGAAACCGACATTGAGGCCAGCCAGGATCCCTGCCACAGGGCATAATGGGCTAGCAACTTTTT
AACGGCAACGGCGGGATCCC

Downstream 100 bases:

>100_bases
GCTGAAGTGGTGATCCCACTCTCATTCCATTGGATGGATCTCTGGACAACCTGTTGGAGTTACCCAAACGCGCCTCGGCG
GAGACAATGAGAGGGGCAGC

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVESVVALAVDLGQGAELEAIQAKALRAGAEQSLVREAVQALITDYAFPAIQ
ANALYEQRYPLSTALARPLIAKLLVEVAEEVGADAVAHGCTGKGNDQVRFDLAIAALNPQLKVLAPAREWGMTREETIAY
GERYGIPMPVQKSSPYSIDLNILGRSAEAGILEDADREPPEEVYALTRPISQTPDEPAYVEIEFEQGIPVGLDGQRLGPK
ALFEQLNSLAGLHGVGRIDMIENRLVGIKSREIYECPALMVLIQAHRELESLTLTRDVIHYKYGIETTYSQLIYNGLWYS
PLREALDAFIRATQKSVTGVVRMRLHKGQAVCVGRRSPYSLYNPELATYGEGDQFDHRAAEGFIYIWGLPTRVWAQVHRG

Sequences:

>Translated_400_residues
MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVESVVALAVDLGQGAELEAIQAKALRAGAEQSLVREAVQALITDYAFPAIQ
ANALYEQRYPLSTALARPLIAKLLVEVAEEVGADAVAHGCTGKGNDQVRFDLAIAALNPQLKVLAPAREWGMTREETIAY
GERYGIPMPVQKSSPYSIDLNILGRSAEAGILEDADREPPEEVYALTRPISQTPDEPAYVEIEFEQGIPVGLDGQRLGPK
ALFEQLNSLAGLHGVGRIDMIENRLVGIKSREIYECPALMVLIQAHRELESLTLTRDVIHYKYGIETTYSQLIYNGLWYS
PLREALDAFIRATQKSVTGVVRMRLHKGQAVCVGRRSPYSLYNPELATYGEGDQFDHRAAEGFIYIWGLPTRVWAQVHRG
>Mature_399_residues
GRAKKVVLAYSGGVDTSVCIPYLKHEWGVESVVALAVDLGQGAELEAIQAKALRAGAEQSLVREAVQALITDYAFPAIQA
NALYEQRYPLSTALARPLIAKLLVEVAEEVGADAVAHGCTGKGNDQVRFDLAIAALNPQLKVLAPAREWGMTREETIAYG
ERYGIPMPVQKSSPYSIDLNILGRSAEAGILEDADREPPEEVYALTRPISQTPDEPAYVEIEFEQGIPVGLDGQRLGPKA
LFEQLNSLAGLHGVGRIDMIENRLVGIKSREIYECPALMVLIQAHRELESLTLTRDVIHYKYGIETTYSQLIYNGLWYSP
LREALDAFIRATQKSVTGVVRMRLHKGQAVCVGRRSPYSLYNPELATYGEGDQFDHRAAEGFIYIWGLPTRVWAQVHRG

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=402, Percent_Identity=41.7910447761194, Blast_Score=298, Evalue=6e-81,
Organism=Homo sapiens, GI16950633, Length=402, Percent_Identity=41.7910447761194, Blast_Score=298, Evalue=6e-81,
Organism=Escherichia coli, GI1789563, Length=395, Percent_Identity=29.620253164557, Blast_Score=125, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324514, Length=410, Percent_Identity=39.7560975609756, Blast_Score=276, Evalue=4e-75,
Organism=Drosophila melanogaster, GI21358151, Length=400, Percent_Identity=38.5, Blast_Score=274, Evalue=7e-74,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44091; Mature: 43960

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVESVVALAVDLGQGAELEAIQAKALRAGAEQ
CCCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHH
SLVREAVQALITDYAFPAIQANALYEQRYPLSTALARPLIAKLLVEVAEEVGADAVAHGC
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TGKGNDQVRFDLAIAALNPQLKVLAPAREWGMTREETIAYGERYGIPMPVQKSSPYSIDL
CCCCCCEEEEEEEEEEECCCEEEEECHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
NILGRSAEAGILEDADREPPEEVYALTRPISQTPDEPAYVEIEFEQGIPVGLDGQRLGPK
EEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHH
ALFEQLNSLAGLHGVGRIDMIENRLVGIKSREIYECPALMVLIQAHRELESLTLTRDVIH
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKYGIETTYSQLIYNGLWYSPLREALDAFIRATQKSVTGVVRMRLHKGQAVCVGRRSPYS
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
LYNPELATYGEGDQFDHRAAEGFIYIWGLPTRVWAQVHRG
CCCCCCCCCCCCCCCCHHHHCCEEEEEECCHHHHHHHCCC
>Mature Secondary Structure 
GRAKKVVLAYSGGVDTSVCIPYLKHEWGVESVVALAVDLGQGAELEAIQAKALRAGAEQ
CCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHH
SLVREAVQALITDYAFPAIQANALYEQRYPLSTALARPLIAKLLVEVAEEVGADAVAHGC
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TGKGNDQVRFDLAIAALNPQLKVLAPAREWGMTREETIAYGERYGIPMPVQKSSPYSIDL
CCCCCCEEEEEEEEEEECCCEEEEECHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
NILGRSAEAGILEDADREPPEEVYALTRPISQTPDEPAYVEIEFEQGIPVGLDGQRLGPK
EEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHH
ALFEQLNSLAGLHGVGRIDMIENRLVGIKSREIYECPALMVLIQAHRELESLTLTRDVIH
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKYGIETTYSQLIYNGLWYSPLREALDAFIRATQKSVTGVVRMRLHKGQAVCVGRRSPYS
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
LYNPELATYGEGDQFDHRAAEGFIYIWGLPTRVWAQVHRG
CCCCCCCCCCCCCCCCHHHHCCEEEEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA