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The map label for this gene is murB [H]

Identifier: 86609025

GI number: 86609025

Start: 1634810

End: 1635796

Strand: Direct

Name: murB [H]

Synonym: CYB_1560

Alternate gene names: 86609025

Gene position: 1634810-1635796 (Clockwise)

Preceding gene: 86609024

Following gene: 86609026

Centisome position: 53.66

GC content: 61.2

Gene sequence:

>987_bases
ATGACGACGGCTCCGGTGGTGCCTCAGCGGGACGGTTCCTGTGAGTCTGAGGCGGCAAGTCTTACCGCTGAAGACAGGCT
TCTCCCCCGCGGGCCGGCGGCTCTGCTATCTGGACGAATTCAATCGGGGATCCCGTTGGCTCCTCTGACCACCTTTCGTG
TGGGCGGCAAGGCCGAGTGGTATTGTGAGCCCCGTAGCCACCTGGAGCTGCAGCAGTGTTTGGCTTGGGCGCGAGCAGAA
GGGATCCCCACGACGCTGTTAGGGGCAGGCAGCAATCTGCTCATCAGCGATGCGGGGTTGAAGGGGCTGGTGATCGGCAC
TCGCCGTTTGCGGGGGATCCAACTGCTGGAAGGGGGGAGAATTTGGGCCGCTGCCGGAGAGCCTTTGGTCAATCTGTCGC
GGGCCGCCGCCAGGCAAGGCTGGAGTGGGTTGGAGTGGGCGATTGGGATCCCGGGCACCCTGGGGGGAGCCGTGGTGATG
AATGCGGGTGCCCACGGACGCGCCATGGCGGATGTGCTGGTGGAAGTGCAGATTTTGGACGAGGAACAAGAGCCCTGCCG
CCTAGAACCTGCCGATCTGCAATTTGGCTATCGCCGCTCTCGCCTGCAAGACTCACCCTGGACGGTGACAGGAGCGACGC
TGCAGTTGATCCCAAGCAGGGATCCGTCCCAGGTGCAGTGGGAAACCCAGCGCTACCTCAACCAACGCCTAAGCTCTCAG
CCCTATCATTTGCCCAGTTGTGGCAGCGTCTTTCGCAACCCAGAGTCTCACCCTGCCGGCTGGCTAATCGAGCAGGTCGG
CTTGAAGGGGTACCGCATCGGTGGGGCCCAAATTTCAGAGCGCCATGCCAACTTCATCCTCAATTGCCATCAGGCGAGTG
CCAAGGACATTTACCGCTTGATTCGCTTGGCCCAGGAAAAGGTCTATCAACAATGGTCGGTGCTTTTGGAGCCGGAAGTG
CGCATTCTGGGATCCTTTGAGGATTAG

Upstream 100 bases:

>100_bases
GAACAGCCTGGGCAAGCCAAAAATCCAAACTTCAGCTGAAAAGGAAAGCCAAAAATCCAAACTTCAGCTGAAAAGATAGC
TGCTTCTGAGGTATTGAATC

Downstream 100 bases:

>100_bases
AAGAGCATCGGCTGGGCAATTTGGCCTGCTTTCTTTTGATGACTTTGATAATTTCGATGATTCTGCTCTTAAACTGTTCT
TACCAGCTTAGATGCTCGTC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTTAPVVPQRDGSCESEAASLTAEDRLLPRGPAALLSGRIQSGIPLAPLTTFRVGGKAEWYCEPRSHLELQQCLAWARAE
GIPTTLLGAGSNLLISDAGLKGLVIGTRRLRGIQLLEGGRIWAAAGEPLVNLSRAAARQGWSGLEWAIGIPGTLGGAVVM
NAGAHGRAMADVLVEVQILDEEQEPCRLEPADLQFGYRRSRLQDSPWTVTGATLQLIPSRDPSQVQWETQRYLNQRLSSQ
PYHLPSCGSVFRNPESHPAGWLIEQVGLKGYRIGGAQISERHANFILNCHQASAKDIYRLIRLAQEKVYQQWSVLLEPEV
RILGSFED

Sequences:

>Translated_328_residues
MTTAPVVPQRDGSCESEAASLTAEDRLLPRGPAALLSGRIQSGIPLAPLTTFRVGGKAEWYCEPRSHLELQQCLAWARAE
GIPTTLLGAGSNLLISDAGLKGLVIGTRRLRGIQLLEGGRIWAAAGEPLVNLSRAAARQGWSGLEWAIGIPGTLGGAVVM
NAGAHGRAMADVLVEVQILDEEQEPCRLEPADLQFGYRRSRLQDSPWTVTGATLQLIPSRDPSQVQWETQRYLNQRLSSQ
PYHLPSCGSVFRNPESHPAGWLIEQVGLKGYRIGGAQISERHANFILNCHQASAKDIYRLIRLAQEKVYQQWSVLLEPEV
RILGSFED
>Mature_327_residues
TTAPVVPQRDGSCESEAASLTAEDRLLPRGPAALLSGRIQSGIPLAPLTTFRVGGKAEWYCEPRSHLELQQCLAWARAEG
IPTTLLGAGSNLLISDAGLKGLVIGTRRLRGIQLLEGGRIWAAAGEPLVNLSRAAARQGWSGLEWAIGIPGTLGGAVVMN
AGAHGRAMADVLVEVQILDEEQEPCRLEPADLQFGYRRSRLQDSPWTVTGATLQLIPSRDPSQVQWETQRYLNQRLSSQP
YHLPSCGSVFRNPESHPAGWLIEQVGLKGYRIGGAQISERHANFILNCHQASAKDIYRLIRLAQEKVYQQWSVLLEPEVR
ILGSFED

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=331, Percent_Identity=27.7945619335347, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35853; Mature: 35722

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPVVPQRDGSCESEAASLTAEDRLLPRGPAALLSGRIQSGIPLAPLTTFRVGGKAEW
CCCCCCCCCCCCCCCHHHHHCCHHCCCCCCCCHHHHHCHHHCCCCCCCCEEEEECCCEEE
YCEPRSHLELQQCLAWARAEGIPTTLLGAGSNLLISDAGLKGLVIGTRRLRGIQLLEGGR
EECCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCEEEEECHHCCCEEEECCCE
IWAAAGEPLVNLSRAAARQGWSGLEWAIGIPGTLGGAVVMNAGAHGRAMADVLVEVQILD
EEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHEEEEEEC
EEQEPCRLEPADLQFGYRRSRLQDSPWTVTGATLQLIPSRDPSQVQWETQRYLNQRLSSQ
CCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCC
PYHLPSCGSVFRNPESHPAGWLIEQVGLKGYRIGGAQISERHANFILNCHQASAKDIYRL
CCCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCCHHHCCCCCEEEEECCCCHHHHHHH
IRLAQEKVYQQWSVLLEPEVRILGSFED
HHHHHHHHHHHHHEEECCCEEEEECCCC
>Mature Secondary Structure 
TTAPVVPQRDGSCESEAASLTAEDRLLPRGPAALLSGRIQSGIPLAPLTTFRVGGKAEW
CCCCCCCCCCCCCCHHHHHCCHHCCCCCCCCHHHHHCHHHCCCCCCCCEEEEECCCEEE
YCEPRSHLELQQCLAWARAEGIPTTLLGAGSNLLISDAGLKGLVIGTRRLRGIQLLEGGR
EECCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCEEEEECHHCCCEEEECCCE
IWAAAGEPLVNLSRAAARQGWSGLEWAIGIPGTLGGAVVMNAGAHGRAMADVLVEVQILD
EEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHEEEEEEC
EEQEPCRLEPADLQFGYRRSRLQDSPWTVTGATLQLIPSRDPSQVQWETQRYLNQRLSSQ
CCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCC
PYHLPSCGSVFRNPESHPAGWLIEQVGLKGYRIGGAQISERHANFILNCHQASAKDIYRL
CCCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCCHHHCCCCCEEEEECCCCHHHHHHH
IRLAQEKVYQQWSVLLEPEVRILGSFED
HHHHHHHHHHHHHEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA