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The map label for this gene is yhdN [H]

Identifier: 86608947

GI number: 86608947

Start: 1554622

End: 1555617

Strand: Direct

Name: yhdN [H]

Synonym: CYB_1480

Alternate gene names: 86608947

Gene position: 1554622-1555617 (Clockwise)

Preceding gene: 86608944

Following gene: 86608948

Centisome position: 51.03

GC content: 61.04

Gene sequence:

>996_bases
ATGGAGTTCATCGATCTTGCCGAGACGGGTCTAAAACTAAGCCGCGTGGGGCTGGGCACCTGGAGCATGACGGGGGATTG
GTGGGGGCCAGCAGATCCTGAGGAGGCCTACGCCACTCTCCGCAAGGCCATTGACCTAGGCATCACCCTCTTTGACACCG
CTCCGGCCTACGGCCGCGGCCTTTCGGAAGTGCTTTTGGGACGGGCCATCCGGGATGCCGGCTGCCGGGATCGCCTAGTC
ATTGCCACCAAGGCCGGCCTGCAGTGGGTCAACGGCAAGGTGGTGCGCAACTGCAGCCTCAGTTGGCTAGCTCAGGATTT
GGAAAACTCCCTCCGCCGCCTGCAGACGGAGGTCATTGACATCTACCAGGTACACTGGCCAGATCCCCTAGAGCCCCTGG
AGGAAACAGCCGCCTTTTTCCAGCGCCTGCTGCAGGAAGGCAAGATCCGCGCCATTGGGGTCAGCAACTTTTCCCCCGAA
CAGATGGATCGGTTTCGCCAGGTGGCTCCTTTGCACACCGCTCAGCCCCCCTACAACCTGTTCGAGCGGCAGATTGAAGC
AGAGGTCTTGCCCTACTGTCGAGAGCACGGCATTCACACCTTGGTGTACAGCCCCCTCTGCCGAGGTCTGCTGAGCGGAC
GGATGACGCCGCAAACCACCTTCCCCCCAGGGGACATGCGCGCCGGGATCGACCCCAAGTTTGTTGAACCGCGCTACTCC
CAGTACCTAAAGGCGGCAGAGGCATTGAGCCAGTTTGCTCAGGATCGCTATGGCAAGACCTTGGCTCAGTTAGCAGTGCG
CTGGCTGCTGGATCAACCAGGGGTGAGTGTGGCACTGTGGGGGGCGCGCAAACCCCATCATCTGGAGGCAATATCCGGCC
TTTGGGGCTGGTCGTTGGATGCGGAAGCGATGCAGACCATCGAGGATATTTTGCAAAGGTATGTTCCCGAGTCCATTCCC
CCCAGCTTTATGTCCCCGCCTGCCCGCGCTGCCTAG

Upstream 100 bases:

>100_bases
CCCAAGGCAGCTAAAAGAGGGAGGTCGTTGGCGCAAGGGGGACTGCCCACCTGCTGACGGTTGCTAGCATGCGGGAGGAG
ACCGCCTCGCAGAAGTTGCC

Downstream 100 bases:

>100_bases
TTGTTGCTTTCTGTTCCCTTGCCGTTTGCGTTAGCGGTGGGGAGCACTTTGTCGCCGGGATCCCAGTCCTACAATTGAGT
TTGGCAAAAAATGGGATGTA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEFIDLAETGLKLSRVGLGTWSMTGDWWGPADPEEAYATLRKAIDLGITLFDTAPAYGRGLSEVLLGRAIRDAGCRDRLV
IATKAGLQWVNGKVVRNCSLSWLAQDLENSLRRLQTEVIDIYQVHWPDPLEPLEETAAFFQRLLQEGKIRAIGVSNFSPE
QMDRFRQVAPLHTAQPPYNLFERQIEAEVLPYCREHGIHTLVYSPLCRGLLSGRMTPQTTFPPGDMRAGIDPKFVEPRYS
QYLKAAEALSQFAQDRYGKTLAQLAVRWLLDQPGVSVALWGARKPHHLEAISGLWGWSLDAEAMQTIEDILQRYVPESIP
PSFMSPPARAA

Sequences:

>Translated_331_residues
MEFIDLAETGLKLSRVGLGTWSMTGDWWGPADPEEAYATLRKAIDLGITLFDTAPAYGRGLSEVLLGRAIRDAGCRDRLV
IATKAGLQWVNGKVVRNCSLSWLAQDLENSLRRLQTEVIDIYQVHWPDPLEPLEETAAFFQRLLQEGKIRAIGVSNFSPE
QMDRFRQVAPLHTAQPPYNLFERQIEAEVLPYCREHGIHTLVYSPLCRGLLSGRMTPQTTFPPGDMRAGIDPKFVEPRYS
QYLKAAEALSQFAQDRYGKTLAQLAVRWLLDQPGVSVALWGARKPHHLEAISGLWGWSLDAEAMQTIEDILQRYVPESIP
PSFMSPPARAA
>Mature_331_residues
MEFIDLAETGLKLSRVGLGTWSMTGDWWGPADPEEAYATLRKAIDLGITLFDTAPAYGRGLSEVLLGRAIRDAGCRDRLV
IATKAGLQWVNGKVVRNCSLSWLAQDLENSLRRLQTEVIDIYQVHWPDPLEPLEETAAFFQRLLQEGKIRAIGVSNFSPE
QMDRFRQVAPLHTAQPPYNLFERQIEAEVLPYCREHGIHTLVYSPLCRGLLSGRMTPQTTFPPGDMRAGIDPKFVEPRYS
QYLKAAEALSQFAQDRYGKTLAQLAVRWLLDQPGVSVALWGARKPHHLEAISGLWGWSLDAEAMQTIEDILQRYVPESIP
PSFMSPPARAA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=305, Percent_Identity=33.4426229508197, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI27436964, Length=301, Percent_Identity=31.8936877076412, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI4504825, Length=302, Percent_Identity=32.7814569536424, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436962, Length=301, Percent_Identity=31.8936877076412, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=297, Percent_Identity=31.986531986532, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI27436971, Length=302, Percent_Identity=27.8145695364238, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718702, Length=190, Percent_Identity=33.1578947368421, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41327764, Length=178, Percent_Identity=36.5168539325843, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=190, Percent_Identity=33.1578947368421, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI24497577, Length=301, Percent_Identity=23.9202657807309, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI5174391, Length=301, Percent_Identity=23.9202657807309, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI223718708, Length=128, Percent_Identity=36.71875, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788070, Length=333, Percent_Identity=34.5345345345345, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789375, Length=304, Percent_Identity=33.8815789473684, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=29.6296296296296, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=29.512893982808, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788081, Length=210, Percent_Identity=34.7619047619048, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994888, Length=190, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082198, Length=311, Percent_Identity=26.6881028938907, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786400, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787674, Length=315, Percent_Identity=23.4920634920635, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564128, Length=332, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=276, Percent_Identity=27.536231884058, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71998625, Length=315, Percent_Identity=24.7619047619048, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17550248, Length=214, Percent_Identity=27.1028037383178, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538386, Length=220, Percent_Identity=28.6363636363636, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=25, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=24.3243243243243, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=303, Percent_Identity=24.4224422442244, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=24.4, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=24.7386759581882, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646155, Length=330, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24646159, Length=161, Percent_Identity=34.1614906832298, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640980, Length=316, Percent_Identity=26.2658227848101, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45549126, Length=316, Percent_Identity=26.2658227848101, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644950, Length=340, Percent_Identity=25.5882352941176, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37157; Mature: 37157

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFIDLAETGLKLSRVGLGTWSMTGDWWGPADPEEAYATLRKAIDLGITLFDTAPAYGRG
CCCHHHHHHCCCHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCHHHCC
LSEVLLGRAIRDAGCRDRLVIATKAGLQWVNGKVVRNCSLSWLAQDLENSLRRLQTEVID
HHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHH
IYQVHWPDPLEPLEETAAFFQRLLQEGKIRAIGVSNFSPEQMDRFRQVAPLHTAQPPYNL
HHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHH
FERQIEAEVLPYCREHGIHTLVYSPLCRGLLSGRMTPQTTFPPGDMRAGIDPKFVEPRYS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QYLKAAEALSQFAQDRYGKTLAQLAVRWLLDQPGVSVALWGARKPHHLEAISGLWGWSLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCC
AEAMQTIEDILQRYVPESIPPSFMSPPARAA
HHHHHHHHHHHHHHCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MEFIDLAETGLKLSRVGLGTWSMTGDWWGPADPEEAYATLRKAIDLGITLFDTAPAYGRG
CCCHHHHHHCCCHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCHHHCC
LSEVLLGRAIRDAGCRDRLVIATKAGLQWVNGKVVRNCSLSWLAQDLENSLRRLQTEVID
HHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHH
IYQVHWPDPLEPLEETAAFFQRLLQEGKIRAIGVSNFSPEQMDRFRQVAPLHTAQPPYNL
HHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHH
FERQIEAEVLPYCREHGIHTLVYSPLCRGLLSGRMTPQTTFPPGDMRAGIDPKFVEPRYS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QYLKAAEALSQFAQDRYGKTLAQLAVRWLLDQPGVSVALWGARKPHHLEAISGLWGWSLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCC
AEAMQTIEDILQRYVPESIPPSFMSPPARAA
HHHHHHHHHHHHHHCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]