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The map label for this gene is ackA

Identifier: 86608853

GI number: 86608853

Start: 1455930

End: 1457141

Strand: Direct

Name: ackA

Synonym: CYB_1384

Alternate gene names: 86608853

Gene position: 1455930-1457141 (Clockwise)

Preceding gene: 86608849

Following gene: 86608854

Centisome position: 47.79

GC content: 61.47

Gene sequence:

>1212_bases
GTGAATATTCTGGTCGTCAATGCCGGTTCCAGCAGCCTCAAATCCTCCCTATTTCTGACGGTTGAGGGAAGGGTGGAGGC
CACGCCCATCTGGCAAGCCCAGGTGGATTTCACCTACAAGCCGGGGGAGGCCCTCATCCAGACTCGTCGGCGAGGCGGTG
GGTGGGAACCTTTTCCCTCCGCTTCACCTGAGGGAGGGATCGGCCAACTGGCCCCGCTGTTTCAAAGCCTCTGGCAAGGG
GAGGGATCCCTGCTCCCGCAGGCGGCTGAGATCGGCGGCGTCGGCCATCGGGTGGTGCATGGGGGATCCCTGTACCGGCA
GCCCACCTTAATTACGCCAGAGGTGGAGAGGGCGATTGAGCAATTGATCCCCTTGGCCCCAGCCCACAACCCTGCTGCGC
TGGCTGGCATCCGTCTGCTAAGGCAACTGTTGCCGGGGATCCCTCAGGTGGCCGTTTTCGACACCGCCTTCCACCAGCAA
ATGCCTCTGGCCGCAGCCCTTTACCCCCTTCCCTACGCTTGGGCTGAACAAGGGATCCGCCGCTACGGGTTTCATGGCAT
CAACCACGAGCATTGCGCCCGTCGCGCTGCCGAGATCTTGAACCGACCCCTGGAGGAGTTGCGGCTGATCACTTGTCACC
TGGGCAACGGCTGCTCGTTGGCGGCCATTCGCGGGGGCAGAAGTGTGGACACCACCATGGGCTACACCCCCCTGGAGGGC
TTGATGATGGGATCCCGGTCGGGGTCGGTGGATCCGGGCATTTTGATCCATCAGTTGCGCCAGGGCATGAGCGTGGATGA
ACTGGATCGGATCTTGAACCGAGAATCGGGGTTGAAGGGCGTTTCCGGCCTGAGCAGCGATATGCGGGTTGTGTTGGAGG
CAATGGAGGCAGGCCATGCCCGGGCGGAGCTGGCTTTTGAGCTGTTTGTTCACCGTCTGCGCAGCCAGATTGGGGCGATG
CTCATGAGCTTAGATCGGCTGGATGCGCTGGTGTTCTCTGGGGGGATTGGGGAAAACTCGGCGCCGGTGCGGGCAGCAGC
CTGTGCAGATCTGGGTTTTTTGGGGATCCAGATCGACCCGGTTTTGAATGCCGGATCCCCCCGCAACTGCGATATCAGCA
CTTCGGATGCTCCGGTGCGGGTTCTGGTGATCTCAGCCCAAGAGGACTGGGCCATTGCCACAGCTTGCCAAAACCTTTTG
CAAGGGGAATAG

Upstream 100 bases:

>100_bases
GCTATGGTCATCCTTAGCGGCAGGGTAGTCAACCGCTCTGTTCAAGCAAGCGGGCTATAGGCCTTAAGCCCAGCAGTGCG
AAGGCCAACGAAGACACGCT

Downstream 100 bases:

>100_bases
ACGAAGGATTCCAGGCTGCTTCTCGCCAGGTTCTCTCCTTTCCGCCCGCTGGCTTGGTGGAGACAAACTCTAGACAATAA
GCTCAAAAAAAGAAGACCTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNILVVNAGSSSLKSSLFLTVEGRVEATPIWQAQVDFTYKPGEALIQTRRRGGGWEPFPSASPEGGIGQLAPLFQSLWQG
EGSLLPQAAEIGGVGHRVVHGGSLYRQPTLITPEVERAIEQLIPLAPAHNPAALAGIRLLRQLLPGIPQVAVFDTAFHQQ
MPLAAALYPLPYAWAEQGIRRYGFHGINHEHCARRAAEILNRPLEELRLITCHLGNGCSLAAIRGGRSVDTTMGYTPLEG
LMMGSRSGSVDPGILIHQLRQGMSVDELDRILNRESGLKGVSGLSSDMRVVLEAMEAGHARAELAFELFVHRLRSQIGAM
LMSLDRLDALVFSGGIGENSAPVRAAACADLGFLGIQIDPVLNAGSPRNCDISTSDAPVRVLVISAQEDWAIATACQNLL
QGE

Sequences:

>Translated_403_residues
MNILVVNAGSSSLKSSLFLTVEGRVEATPIWQAQVDFTYKPGEALIQTRRRGGGWEPFPSASPEGGIGQLAPLFQSLWQG
EGSLLPQAAEIGGVGHRVVHGGSLYRQPTLITPEVERAIEQLIPLAPAHNPAALAGIRLLRQLLPGIPQVAVFDTAFHQQ
MPLAAALYPLPYAWAEQGIRRYGFHGINHEHCARRAAEILNRPLEELRLITCHLGNGCSLAAIRGGRSVDTTMGYTPLEG
LMMGSRSGSVDPGILIHQLRQGMSVDELDRILNRESGLKGVSGLSSDMRVVLEAMEAGHARAELAFELFVHRLRSQIGAM
LMSLDRLDALVFSGGIGENSAPVRAAACADLGFLGIQIDPVLNAGSPRNCDISTSDAPVRVLVISAQEDWAIATACQNLL
QGE
>Mature_403_residues
MNILVVNAGSSSLKSSLFLTVEGRVEATPIWQAQVDFTYKPGEALIQTRRRGGGWEPFPSASPEGGIGQLAPLFQSLWQG
EGSLLPQAAEIGGVGHRVVHGGSLYRQPTLITPEVERAIEQLIPLAPAHNPAALAGIRLLRQLLPGIPQVAVFDTAFHQQ
MPLAAALYPLPYAWAEQGIRRYGFHGINHEHCARRAAEILNRPLEELRLITCHLGNGCSLAAIRGGRSVDTTMGYTPLEG
LMMGSRSGSVDPGILIHQLRQGMSVDELDRILNRESGLKGVSGLSSDMRVVLEAMEAGHARAELAFELFVHRLRSQIGAM
LMSLDRLDALVFSGGIGENSAPVRAAACADLGFLGIQIDPVLNAGSPRNCDISTSDAPVRVLVISAQEDWAIATACQNLL
QGE

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=42.4242424242424, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1788633, Length=366, Percent_Identity=42.896174863388, Blast_Score=271, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_SYNJB (Q2JLQ2)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477615.1
- ProteinModelPortal:   Q2JLQ2
- SMR:   Q2JLQ2
- STRING:   Q2JLQ2
- GeneID:   3901251
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1384
- TIGR:   CYB_1384
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   IDMEREV
- PhylomeDB:   Q2JLQ2
- ProtClustDB:   PRK00180
- BioCyc:   SSP321332:CYB_1384-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43216; Mature: 43216

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVVNAGSSSLKSSLFLTVEGRVEATPIWQAQVDFTYKPGEALIQTRRRGGGWEPFPS
CEEEEEECCCHHCCCEEEEEEECCEEECEEEEEEEEEEECCHHHHHHHHHCCCCCCCCCC
ASPEGGIGQLAPLFQSLWQGEGSLLPQAAEIGGVGHRVVHGGSLYRQPTLITPEVERAIE
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHEEECCCCCCCCCEECHHHHHHHH
QLIPLAPAHNPAALAGIRLLRQLLPGIPQVAVFDTAFHQQMPLAAALYPLPYAWAEQGIR
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCHHHHHCCCCHHHHHHHHH
RYGFHGINHEHCARRAAEILNRPLEELRLITCHLGNGCSLAAIRGGRSVDTTMGYTPLEG
HHCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHH
LMMGSRSGSVDPGILIHQLRQGMSVDELDRILNRESGLKGVSGLSSDMRVVLEAMEAGHA
HEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCH
RAELAFELFVHRLRSQIGAMLMSLDRLDALVFSGGIGENSAPVRAAACADLGFLGIQIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEECC
VLNAGSPRNCDISTSDAPVRVLVISAQEDWAIATACQNLLQGE
CCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILVVNAGSSSLKSSLFLTVEGRVEATPIWQAQVDFTYKPGEALIQTRRRGGGWEPFPS
CEEEEEECCCHHCCCEEEEEEECCEEECEEEEEEEEEEECCHHHHHHHHHCCCCCCCCCC
ASPEGGIGQLAPLFQSLWQGEGSLLPQAAEIGGVGHRVVHGGSLYRQPTLITPEVERAIE
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHEEECCCCCCCCCEECHHHHHHHH
QLIPLAPAHNPAALAGIRLLRQLLPGIPQVAVFDTAFHQQMPLAAALYPLPYAWAEQGIR
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCHHHHHCCCCHHHHHHHHH
RYGFHGINHEHCARRAAEILNRPLEELRLITCHLGNGCSLAAIRGGRSVDTTMGYTPLEG
HHCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHH
LMMGSRSGSVDPGILIHQLRQGMSVDELDRILNRESGLKGVSGLSSDMRVVLEAMEAGHA
HEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCH
RAELAFELFVHRLRSQIGAMLMSLDRLDALVFSGGIGENSAPVRAAACADLGFLGIQIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEECC
VLNAGSPRNCDISTSDAPVRVLVISAQEDWAIATACQNLLQGE
CCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA