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The map label for this gene is ald [H]

Identifier: 86608832

GI number: 86608832

Start: 1429582

End: 1430670

Strand: Direct

Name: ald [H]

Synonym: CYB_1358

Alternate gene names: 86608832

Gene position: 1429582-1430670 (Clockwise)

Preceding gene: 86608831

Following gene: 86608837

Centisome position: 46.92

GC content: 63.18

Gene sequence:

>1089_bases
ATGCGAATTGGCGTGCCCAAAGAGATCAAAGAGCAAGAGTTCCGTGTCGGGCTGACACCGGCGGCGGTGCGGGTCTTAAC
CGAACAGGGGCATCAGGTGTGGGTGGAAACCCAAGCAGGCCAGGGGGCGGGCTTCACGGATGAGGACTACCAAAAAGCGG
GGGCCAAGCTGGCTGTCACTCCTGAGGAGATCTACCGGCAGGAGCTGGTGGTGAAGGTCAAGGAGCCCCTGCCGGCTGAG
TATTCTCTGCTCCATCCCGACCTTATTCTGTTCACCTATTTGCACTTGGCCGCCAGCCGCGAGCTGACCCAGGCGCTGCT
GCAGTCGGGAGCCACCTGCCTCGCCTATGAAACGGTGGAATGGGCGGATGGATCCCTGCCCTTGTTGATGCCCATGAGCA
TGATTGCCGGGCGGCTCTCGGTGCAGTTTGGCGCCCATTACCTGACCCGACAGCAGGGGGGGCGGGGCGTGTTGCTGGGC
GGGATCCCGGGGGTGCCGCCGGGGCGGGTGGTGATCCTGGGCGGGGGAACCGTGGGCACTGAGGCGGCCAAAATGGCCGT
AGGCTTGGGGGCACGGGTGCAGATTTTGGACATTAACCTGCAGCGGCTGAACGAGCTGGAGCTGATTTTTGGCTCGCGGG
TAGAGCTGCTCTACAGCACGGCCCAAAGCGTGGAAGAGTGTGTTCGCGAGGCCGACCTGGTGGTAGGGGCAGTGTTGGTG
CCGGGAAGGCGGGCGCCGGTCTTGGTGGGAGAAGAGTTGGTGGCCCAAATGCGTCCTCGCTCCCTCATTGTGGATGTGGC
GGTGGATCAGGGGGGGTGCATCGCTACCACGCGGGTTACCACCCATGCCCAGCCGGTTTACGAAGCCCACGGGGTGTTGC
ACTACGGCGTTCCCAACATGCCCGGAGCCGTTCCCTGGACTTCGACCCAAGCGCTGGTCAACGCCACACTCCCCTACATC
CTCAAGCTGGCCAATCTCGGCTTGCCCGCTGCTTTGGAACAAGACTCGGCCTTGGCCAAAGGGCTCAACATCAGGGCAGG
AAAGATCGTCCACCCGGCGGTGCGGGCCACTTTTCCAGATTTGGGCTAG

Upstream 100 bases:

>100_bases
CGCGCACAAAACTTTACAATTTTCGCTCTCCTGCTCAGGCCAGGGATCCCATCGGGGAGAGAGTCTGTCTAGACTGGAAA
GCAGCCCTACGGGGATCCCT

Downstream 100 bases:

>100_bases
CTTGTTCAGGCATCGGTGGGATCCCCTGGAGCAGATGCTACTGTCGCCAGGACAGGACATAGCGCTCCAAAGCCGCAAAA
AAGGTGTAGAGCAAAATGCC

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MRIGVPKEIKEQEFRVGLTPAAVRVLTEQGHQVWVETQAGQGAGFTDEDYQKAGAKLAVTPEEIYRQELVVKVKEPLPAE
YSLLHPDLILFTYLHLAASRELTQALLQSGATCLAYETVEWADGSLPLLMPMSMIAGRLSVQFGAHYLTRQQGGRGVLLG
GIPGVPPGRVVILGGGTVGTEAAKMAVGLGARVQILDINLQRLNELELIFGSRVELLYSTAQSVEECVREADLVVGAVLV
PGRRAPVLVGEELVAQMRPRSLIVDVAVDQGGCIATTRVTTHAQPVYEAHGVLHYGVPNMPGAVPWTSTQALVNATLPYI
LKLANLGLPAALEQDSALAKGLNIRAGKIVHPAVRATFPDLG

Sequences:

>Translated_362_residues
MRIGVPKEIKEQEFRVGLTPAAVRVLTEQGHQVWVETQAGQGAGFTDEDYQKAGAKLAVTPEEIYRQELVVKVKEPLPAE
YSLLHPDLILFTYLHLAASRELTQALLQSGATCLAYETVEWADGSLPLLMPMSMIAGRLSVQFGAHYLTRQQGGRGVLLG
GIPGVPPGRVVILGGGTVGTEAAKMAVGLGARVQILDINLQRLNELELIFGSRVELLYSTAQSVEECVREADLVVGAVLV
PGRRAPVLVGEELVAQMRPRSLIVDVAVDQGGCIATTRVTTHAQPVYEAHGVLHYGVPNMPGAVPWTSTQALVNATLPYI
LKLANLGLPAALEQDSALAKGLNIRAGKIVHPAVRATFPDLG
>Mature_362_residues
MRIGVPKEIKEQEFRVGLTPAAVRVLTEQGHQVWVETQAGQGAGFTDEDYQKAGAKLAVTPEEIYRQELVVKVKEPLPAE
YSLLHPDLILFTYLHLAASRELTQALLQSGATCLAYETVEWADGSLPLLMPMSMIAGRLSVQFGAHYLTRQQGGRGVLLG
GIPGVPPGRVVILGGGTVGTEAAKMAVGLGARVQILDINLQRLNELELIFGSRVELLYSTAQSVEECVREADLVVGAVLV
PGRRAPVLVGEELVAQMRPRSLIVDVAVDQGGCIATTRVTTHAQPVYEAHGVLHYGVPNMPGAVPWTSTQALVNATLPYI
LKLANLGLPAALEQDSALAKGLNIRAGKIVHPAVRATFPDLG

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=352, Percent_Identity=30.6818181818182, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI122939153, Length=352, Percent_Identity=30.6818181818182, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1787887, Length=387, Percent_Identity=32.0413436692506, Blast_Score=141, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17550456, Length=371, Percent_Identity=28.3018867924528, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38688; Mature: 38688

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVPKEIKEQEFRVGLTPAAVRVLTEQGHQVWVETQAGQGAGFTDEDYQKAGAKLAVT
CCCCCCHHHHHHHHEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCEEEEC
PEEIYRQELVVKVKEPLPAEYSLLHPDLILFTYLHLAASRELTQALLQSGATCLAYETVE
HHHHHHHHHHEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
WADGSLPLLMPMSMIAGRLSVQFGAHYLTRQQGGRGVLLGGIPGVPPGRVVILGGGTVGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCH
EAAKMAVGLGARVQILDINLQRLNELELIFGSRVELLYSTAQSVEECVREADLVVGAVLV
HHHHHHHCCCCEEEEEECCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEE
PGRRAPVLVGEELVAQMRPRSLIVDVAVDQGGCIATTRVTTHAQPVYEAHGVLHYGVPNM
CCCCCCEEECHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCCCHHHHCCEEEECCCCC
PGAVPWTSTQALVNATLPYILKLANLGLPAALEQDSALAKGLNIRAGKIVHPAVRATFPD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEECHHHHCCCCC
LG
CC
>Mature Secondary Structure
MRIGVPKEIKEQEFRVGLTPAAVRVLTEQGHQVWVETQAGQGAGFTDEDYQKAGAKLAVT
CCCCCCHHHHHHHHEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCEEEEC
PEEIYRQELVVKVKEPLPAEYSLLHPDLILFTYLHLAASRELTQALLQSGATCLAYETVE
HHHHHHHHHHEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
WADGSLPLLMPMSMIAGRLSVQFGAHYLTRQQGGRGVLLGGIPGVPPGRVVILGGGTVGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCH
EAAKMAVGLGARVQILDINLQRLNELELIFGSRVELLYSTAQSVEECVREADLVVGAVLV
HHHHHHHCCCCEEEEEECCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEE
PGRRAPVLVGEELVAQMRPRSLIVDVAVDQGGCIATTRVTTHAQPVYEAHGVLHYGVPNM
CCCCCCEEECHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCCCHHHHCCEEEECCCCC
PGAVPWTSTQALVNATLPYILKLANLGLPAALEQDSALAKGLNIRAGKIVHPAVRATFPD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEECHHHHCCCCC
LG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2340274 [H]