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The map label for this gene is dapL [H]

Identifier: 86608738

GI number: 86608738

Start: 1319040

End: 1320236

Strand: Reverse

Name: dapL [H]

Synonym: CYB_1262

Alternate gene names: 86608738

Gene position: 1320236-1319040 (Counterclockwise)

Preceding gene: 86608742

Following gene: 86608736

Centisome position: 43.33

GC content: 63.58

Gene sequence:

>1197_bases
ATGAACCGCGCTCTCGTTCCCGCCCAGCGGCTGAACAAGCTGCCCGCCTATGTCTTCGCCCGCTTGGATGAGCTGAAGGC
CCGCGCCCGCCAGCAGGGGTTGGATTTGATCGATCTGGGCATGGGCAACCCCGATGGTCCCACCCCACAGCCGGTGGTGG
AGGCGGCGCAGGCGGCCATTGCGGATCCCGCCCACCACGGCTACCCGCCCTTTGAGGGCACGGCCAGCTTCCGCCAGGCG
ATCACGGATTGGTACTGGCGCCGCTACGGGGTGGAGCTGGATCCCAATGGAGAGGCGCTGCCTTTGCTGGGATCCAAAGA
GGGGCTGACCCACCTGGCTCTGGCCTATGTGGATCCCGGAGATCTGGTGTTGGTGCCCAGCCCTGCCTATCCAGCCCATT
TTCGCGGCCCCATGATTGCCGGCGGGCAGATCTACCCGATGATGCTGCGCCCGCAGAAGGGGTGGTTGATCGATCTGCAA
GAAATACCGCCGGAAGTGGCCCAGCAAGCGCGGGTGCTCTACTTTAACTACCCCAACAACCCGACGGCGGCAGTTGCGCC
CCGCTCTTTTTTTGAGGAGGTGGTGGAGTTTGCCCACCGCTACGATCTCATCCTGGTGCACGACCTGTGCTATGCCGAGC
TGGCTTTTGACGGCTACCGGCCCACCAGCCTGCTGCAGATCCCAGGGGCCAAGGACTTGGCAGTGGAGTTCCACACCCTC
TCCAAAACCTACAACATGGCCGGCTGGCGGGTGGGATTTGTGGTGGGCAATCGCCAGATCATCCAGAGCTTGCGCACCCT
GAAAACCAATCTCGACTACGGCATTTTTGCCGCCATCCAAAAGGCCGCCGAAACTGCCCTGCGCCTGCCGGATAGCTACC
TGGAGCAGGTACAAGAGCGCTACCGCCGCCGGCGCGACTATCTGATCGGCCGCCTAGCGGAGTTGGGCTGGCGGATCGAG
CCGCCACGGGCGACGATGTATCTCTGGATCCCTACCCCCCGCGCTGCCGACGGCACCCCTGAGGGATCGACGGAGTTTGC
CCTGCGGGTGCTGGAATCTACAGGCGTGGTCGTAACCCCCGGCAGCGCTTTTGGAGAGGGAGGAGAGGGCTACGTGCGGA
TTAGCCTAATTGCCGATTGCGAGCGCATAGGTCAGGCTATCGATCGCTGGGCGGAAGCCGGGATCCGCTACTGCTGA

Upstream 100 bases:

>100_bases
AGCCGCCAATCTCGATCATTGCTTTGGATGCAGGTCTGGCGGTAAGTTAGGTACCTATCCTCCCATCAGGCACCGGCTGT
GCCCCTTCCCCATTCTTGCC

Downstream 100 bases:

>100_bases
GCCTCAGTCTTGCGGGAGTTGGTACTGCTCCACAATCCGCCGGGCAAAGGGGGGCACGTGCTGCTCCAACTTCTGGGGAT
AGTGGCGGCGCACGTAGAGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNRALVPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAIADPAHHGYPPFEGTASFRQA
ITDWYWRRYGVELDPNGEALPLLGSKEGLTHLALAYVDPGDLVLVPSPAYPAHFRGPMIAGGQIYPMMLRPQKGWLIDLQ
EIPPEVAQQARVLYFNYPNNPTAAVAPRSFFEEVVEFAHRYDLILVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFAAIQKAAETALRLPDSYLEQVQERYRRRRDYLIGRLAELGWRIE
PPRATMYLWIPTPRAADGTPEGSTEFALRVLESTGVVVTPGSAFGEGGEGYVRISLIADCERIGQAIDRWAEAGIRYC

Sequences:

>Translated_398_residues
MNRALVPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAIADPAHHGYPPFEGTASFRQA
ITDWYWRRYGVELDPNGEALPLLGSKEGLTHLALAYVDPGDLVLVPSPAYPAHFRGPMIAGGQIYPMMLRPQKGWLIDLQ
EIPPEVAQQARVLYFNYPNNPTAAVAPRSFFEEVVEFAHRYDLILVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFAAIQKAAETALRLPDSYLEQVQERYRRRRDYLIGRLAELGWRIE
PPRATMYLWIPTPRAADGTPEGSTEFALRVLESTGVVVTPGSAFGEGGEGYVRISLIADCERIGQAIDRWAEAGIRYC
>Mature_398_residues
MNRALVPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAIADPAHHGYPPFEGTASFRQA
ITDWYWRRYGVELDPNGEALPLLGSKEGLTHLALAYVDPGDLVLVPSPAYPAHFRGPMIAGGQIYPMMLRPQKGWLIDLQ
EIPPEVAQQARVLYFNYPNNPTAAVAPRSFFEEVVEFAHRYDLILVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFAAIQKAAETALRLPDSYLEQVQERYRRRRDYLIGRLAELGWRIE
PPRATMYLWIPTPRAADGTPEGSTEFALRVLESTGVVVTPGSAFGEGGEGYVRISLIADCERIGQAIDRWAEAGIRYC

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=26.4248704663212, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=26.4248704663212, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI56713254, Length=334, Percent_Identity=23.3532934131737, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI56713256, Length=334, Percent_Identity=23.3532934131737, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI169881281, Length=374, Percent_Identity=24.331550802139, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4507369, Length=363, Percent_Identity=24.2424242424242, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=46.0526315789474, Blast_Score=347, Evalue=5e-97,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=27.4725274725275, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788627, Length=382, Percent_Identity=26.7015706806283, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=394, Percent_Identity=24.6192893401015, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=394, Percent_Identity=24.6192893401015, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=264, Percent_Identity=25, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=392, Percent_Identity=24.234693877551, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=20.671834625323, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320317, Length=351, Percent_Identity=25.3561253561254, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=358, Percent_Identity=24.3016759776536, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=24.8704663212435, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=24.8704663212435, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=24.8704663212435, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=24.8704663212435, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859735, Length=385, Percent_Identity=24.1558441558442, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44366; Mature: 44366

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRALVPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAI
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHH
ADPAHHGYPPFEGTASFRQAITDWYWRRYGVELDPNGEALPLLGSKEGLTHLALAYVDPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCEEECCCCCCCCCEEEEEEECCC
DLVLVPSPAYPAHFRGPMIAGGQIYPMMLRPQKGWLIDLQEIPPEVAQQARVLYFNYPNN
CEEEECCCCCCCCCCCCEEECCEEEEEEEECCCCCEEEHHHCCHHHHCCCEEEEEECCCC
PTAAVAPRSFFEEVVEFAHRYDLILVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
CCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEHH
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFAAIQKAAETALRLPDSYLEQVQER
HHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YRRRRDYLIGRLAELGWRIEPPRATMYLWIPTPRAADGTPEGSTEFALRVLESTGVVVTP
HHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEC
GSAFGEGGEGYVRISLIADCERIGQAIDRWAEAGIRYC
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRALVPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAI
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHH
ADPAHHGYPPFEGTASFRQAITDWYWRRYGVELDPNGEALPLLGSKEGLTHLALAYVDPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCEEECCCCCCCCCEEEEEEECCC
DLVLVPSPAYPAHFRGPMIAGGQIYPMMLRPQKGWLIDLQEIPPEVAQQARVLYFNYPNN
CEEEECCCCCCCCCCCCEEECCEEEEEEEECCCCCEEEHHHCCHHHHCCCEEEEEECCCC
PTAAVAPRSFFEEVVEFAHRYDLILVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
CCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEHH
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFAAIQKAAETALRLPDSYLEQVQER
HHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YRRRRDYLIGRLAELGWRIEPPRATMYLWIPTPRAADGTPEGSTEFALRVLESTGVVVTP
HHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEC
GSAFGEGGEGYVRISLIADCERIGQAIDRWAEAGIRYC
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA