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The map label for this gene is aspS [H]

Identifier: 86608637

GI number: 86608637

Start: 1199191

End: 1200996

Strand: Reverse

Name: aspS [H]

Synonym: CYB_1161

Alternate gene names: 86608637

Gene position: 1200996-1199191 (Counterclockwise)

Preceding gene: 86608638

Following gene: 86608636

Centisome position: 39.42

GC content: 61.41

Gene sequence:

>1806_bases
ATGCCTGCTGCCATCCATCGCCCGGCCCGCACCCTCTACTGTGGCGAAGTCCGCCCGGCCCACATTGGCCAGACCGTCAC
CCTCTACGGCTGGATCGACCGCCGCCGCGACCACGGGGGGGTGATCTTTCTGGATTTGCGGGATCGCTCTGGCATTGTGC
AACTGGTGGCGGATCCGCAGAAAACTCCGCAGTCATATCCACTGGCGGGGGAAGTGCGCAACGAATATGTGGTGCGGGTA
ACGGGAACTGTCCAGCAACGGCCCCCCGACTCCTTCAACCCTCGCCTGGCCACCGGCGAGGTCGAGATCTACGCCGAACA
GTTGGAAGTGCTCAGTCCAGTCGGCAAGCAGCTCCCCTTCAGCGTCTCGGGAGAAGAAGCAGAGGAAGTGCGAGAAGAGA
TCCGCCTGCGCTATCGCTACCTGGATTTGCGGCGGGAGCGCATGTCCCGTAACCTGCAACTGCGCCACCGGGTCATCCAG
GCCATCCGCCGTTTCCTAGAAGACGAGGAGGGCTTTGTCGAGGTGGAGACTCCCATTCTCACCCGCTCCACCCCAGAAGG
GGCCAGAGACTACCTGGTGCCCAGCCGCGTCAACCCCGGCGAGTGGTTTGCCCTGCCGCAGTCGCCCCAGCTCTTTAAGC
AGCTGCTGATGGTGGCTGGCGTGGATCGCTACTACCAGATCGCCCGCTGCTTTCGGGATGAGGATCTGCGGGCGGATCGG
CAGCCGGAGTTCACCCAGTTGGACATGGAGATGAGCTTCATGGATCAAGAAGGGATCCTGGAGCTCAACGAGCGACTGAT
CTGCCATATCTTCAAAACTGTCAAAGGGATCCACCTGCCCCGTCCCTTCCCGCGCCTGACCTATGCCGAGGCCATGGCCC
GCTACGGCTCCGACAAGCCTGACACCCGCTTTGGGATGGAGTTGGTGGATGTTTCGGAGGTGTTTCAGGGATCCCGATTC
AAAGTCTTCGCCAAAGTGCTGGCTGAGGGCGGTTTGATCAAAATCCTGCCAGTGCCCGGCGGCGATGAAAAGATCTCCAA
CACCCGCATCAAACCAGGCGGGGATCTGTTCAAGCTGGTCACCCAGTATGGGGCGGGCGGCTTGGCCTTTATCCGGGTGC
GGCCCGACAGCCTCGATACCATCGGCGCCCTGAAAGAGAGCTTGAGCCCCGAGCAGGAGAAGCGGTTGCTGGATCTCACC
CAGGCCAAGCCAGGGGATCTGTTGCTGTTTGGGGCAGGGCCGGCGGCAGTGGTGAACGAGTCTTTGGGCCGGCTGCGGCT
GCACCTGGGCCAGGAGCTGGGTTTGATCCCAGAGAACGCCTTGAATCTCCTCTGGATCACCGACTTTCCCATGTTTGAGT
TCAACGCCGAAGAAAATCGCCTGGAAGCCCTGCACCACCCCTTTACCGCCCCCCACCCCGACGACTTGGCCGACCTGAAA
ACGGCGCGGGCCCAGGCTTATGACCTGGTGTGGAACGGCGTGGAAGTAGGAGGGGGATCCCTGCGGATTTACCAGCGGGA
AATTCAGGAGCAGGTTTTTCAAGCGATTGGCCTCACCCCCGAACAGGCGCGGGACAAGTTTGGCTTTTTGTTGGAAGCCT
TTGAGTATGGCACCCCGCCCCACGGCGGCATTGCCTACGGCCTGGATCGGCTGGTGATGTTGCTGGCCGGGGAAGATTCC
ATCCGGGATGTCATCGCCTTTCCCAAAACCCAGCAGGCGCGATGTTTGCTCACCGGCGCTCCTTCCAGCGTTGAGGCGAA
GCAGCTCAAGGAACTGCACGTTGCTTCCACCTATCAGCCCGGTTGA

Upstream 100 bases:

>100_bases
CCTGGGCGGATCCCCTGACTGCTCTTGAGAAGCTGAGTCGAGGCAGGAGGTCTGAGTTTTGTATGATAGGGGCTCAGACC
CTTGTTCTCTCACCTCTTCC

Downstream 100 bases:

>100_bases
GGGAGGTATCTTCCAACGACCACGGGTGCTCGATGATTTCGGCACGGGTAACAGGGCTGCGGAGATCCAGCAGACAATAT
TCCTTTTCAACCAAAAGGAC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MPAAIHRPARTLYCGEVRPAHIGQTVTLYGWIDRRRDHGGVIFLDLRDRSGIVQLVADPQKTPQSYPLAGEVRNEYVVRV
TGTVQQRPPDSFNPRLATGEVEIYAEQLEVLSPVGKQLPFSVSGEEAEEVREEIRLRYRYLDLRRERMSRNLQLRHRVIQ
AIRRFLEDEEGFVEVETPILTRSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVAGVDRYYQIARCFRDEDLRADR
QPEFTQLDMEMSFMDQEGILELNERLICHIFKTVKGIHLPRPFPRLTYAEAMARYGSDKPDTRFGMELVDVSEVFQGSRF
KVFAKVLAEGGLIKILPVPGGDEKISNTRIKPGGDLFKLVTQYGAGGLAFIRVRPDSLDTIGALKESLSPEQEKRLLDLT
QAKPGDLLLFGAGPAAVVNESLGRLRLHLGQELGLIPENALNLLWITDFPMFEFNAEENRLEALHHPFTAPHPDDLADLK
TARAQAYDLVWNGVEVGGGSLRIYQREIQEQVFQAIGLTPEQARDKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEDS
IRDVIAFPKTQQARCLLTGAPSSVEAKQLKELHVASTYQPG

Sequences:

>Translated_601_residues
MPAAIHRPARTLYCGEVRPAHIGQTVTLYGWIDRRRDHGGVIFLDLRDRSGIVQLVADPQKTPQSYPLAGEVRNEYVVRV
TGTVQQRPPDSFNPRLATGEVEIYAEQLEVLSPVGKQLPFSVSGEEAEEVREEIRLRYRYLDLRRERMSRNLQLRHRVIQ
AIRRFLEDEEGFVEVETPILTRSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVAGVDRYYQIARCFRDEDLRADR
QPEFTQLDMEMSFMDQEGILELNERLICHIFKTVKGIHLPRPFPRLTYAEAMARYGSDKPDTRFGMELVDVSEVFQGSRF
KVFAKVLAEGGLIKILPVPGGDEKISNTRIKPGGDLFKLVTQYGAGGLAFIRVRPDSLDTIGALKESLSPEQEKRLLDLT
QAKPGDLLLFGAGPAAVVNESLGRLRLHLGQELGLIPENALNLLWITDFPMFEFNAEENRLEALHHPFTAPHPDDLADLK
TARAQAYDLVWNGVEVGGGSLRIYQREIQEQVFQAIGLTPEQARDKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEDS
IRDVIAFPKTQQARCLLTGAPSSVEAKQLKELHVASTYQPG
>Mature_600_residues
PAAIHRPARTLYCGEVRPAHIGQTVTLYGWIDRRRDHGGVIFLDLRDRSGIVQLVADPQKTPQSYPLAGEVRNEYVVRVT
GTVQQRPPDSFNPRLATGEVEIYAEQLEVLSPVGKQLPFSVSGEEAEEVREEIRLRYRYLDLRRERMSRNLQLRHRVIQA
IRRFLEDEEGFVEVETPILTRSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVAGVDRYYQIARCFRDEDLRADRQ
PEFTQLDMEMSFMDQEGILELNERLICHIFKTVKGIHLPRPFPRLTYAEAMARYGSDKPDTRFGMELVDVSEVFQGSRFK
VFAKVLAEGGLIKILPVPGGDEKISNTRIKPGGDLFKLVTQYGAGGLAFIRVRPDSLDTIGALKESLSPEQEKRLLDLTQ
AKPGDLLLFGAGPAAVVNESLGRLRLHLGQELGLIPENALNLLWITDFPMFEFNAEENRLEALHHPFTAPHPDDLADLKT
ARAQAYDLVWNGVEVGGGSLRIYQREIQEQVFQAIGLTPEQARDKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEDSI
RDVIAFPKTQQARCLLTGAPSSVEAKQLKELHVASTYQPG

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=605, Percent_Identity=41.8181818181818, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI5031815, Length=259, Percent_Identity=30.1158301158301, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI194272210, Length=259, Percent_Identity=30.1158301158301, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI45439306, Length=307, Percent_Identity=27.0358306188925, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788173, Length=593, Percent_Identity=50.0843170320405, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1789256, Length=290, Percent_Identity=28.2758620689655, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790571, Length=290, Percent_Identity=28.9655172413793, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32566633, Length=603, Percent_Identity=37.3134328358209, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI71994340, Length=262, Percent_Identity=27.0992366412214, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17535927, Length=262, Percent_Identity=27.0992366412214, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17535925, Length=262, Percent_Identity=27.0992366412214, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17551876, Length=283, Percent_Identity=26.1484098939929, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71984122, Length=294, Percent_Identity=27.891156462585, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325153, Length=632, Percent_Identity=33.3860759493671, Blast_Score=266, Evalue=7e-72,
Organism=Saccharomyces cerevisiae, GI6320242, Length=275, Percent_Identity=27.6363636363636, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321807, Length=340, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323011, Length=277, Percent_Identity=28.5198555956679, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324256, Length=184, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24584738, Length=605, Percent_Identity=41.1570247933884, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24640849, Length=257, Percent_Identity=27.2373540856031, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24640851, Length=257, Percent_Identity=27.2373540856031, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136276, Length=245, Percent_Identity=29.3877551020408, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921528, Length=283, Percent_Identity=28.2685512367491, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922416, Length=345, Percent_Identity=23.768115942029, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67707; Mature: 67576

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAIHRPARTLYCGEVRPAHIGQTVTLYGWIDRRRDHGGVIFLDLRDRSGIVQLVADPQ
CCCCCCCCCCEEEECCCCHHHCCCEEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCC
KTPQSYPLAGEVRNEYVVRVTGTVQQRPPDSFNPRLATGEVEIYAEQLEVLSPVGKQLPF
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCC
SVSGEEAEEVREEIRLRYRYLDLRRERMSRNLQLRHRVIQAIRRFLEDEEGFVEVETPIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCEE
TRSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVAGVDRYYQIARCFRDEDLRADR
ECCCCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
QPEFTQLDMEMSFMDQEGILELNERLICHIFKTVKGIHLPRPFPRLTYAEAMARYGSDKP
CCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
DTRFGMELVDVSEVFQGSRFKVFAKVLAEGGLIKILPVPGGDEKISNTRIKPGGDLFKLV
CCHHCHHHEEHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
TQYGAGGLAFIRVRPDSLDTIGALKESLSPEQEKRLLDLTQAKPGDLLLFGAGPAAVVNE
HHHCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHH
SLGRLRLHLGQELGLIPENALNLLWITDFPMFEFNAEENRLEALHHPFTAPHPDDLADLK
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCHHHHHHHHCCCCCCCCCCHHHHH
TARAQAYDLVWNGVEVGGGSLRIYQREIQEQVFQAIGLTPEQARDKFGFLLEAFEYGTPP
HHHHHHHHHEECCEEECCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
HGGIAYGLDRLVMLLAGEDSIRDVIAFPKTQQARCLLTGAPSSVEAKQLKELHVASTYQP
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCC
G
C
>Mature Secondary Structure 
PAAIHRPARTLYCGEVRPAHIGQTVTLYGWIDRRRDHGGVIFLDLRDRSGIVQLVADPQ
CCCCCCCCCEEEECCCCHHHCCCEEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCC
KTPQSYPLAGEVRNEYVVRVTGTVQQRPPDSFNPRLATGEVEIYAEQLEVLSPVGKQLPF
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCC
SVSGEEAEEVREEIRLRYRYLDLRRERMSRNLQLRHRVIQAIRRFLEDEEGFVEVETPIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCEE
TRSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVAGVDRYYQIARCFRDEDLRADR
ECCCCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
QPEFTQLDMEMSFMDQEGILELNERLICHIFKTVKGIHLPRPFPRLTYAEAMARYGSDKP
CCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
DTRFGMELVDVSEVFQGSRFKVFAKVLAEGGLIKILPVPGGDEKISNTRIKPGGDLFKLV
CCHHCHHHEEHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
TQYGAGGLAFIRVRPDSLDTIGALKESLSPEQEKRLLDLTQAKPGDLLLFGAGPAAVVNE
HHHCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHH
SLGRLRLHLGQELGLIPENALNLLWITDFPMFEFNAEENRLEALHHPFTAPHPDDLADLK
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCHHHHHHHHCCCCCCCCCCHHHHH
TARAQAYDLVWNGVEVGGGSLRIYQREIQEQVFQAIGLTPEQARDKFGFLLEAFEYGTPP
HHHHHHHHHEECCEEECCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
HGGIAYGLDRLVMLLAGEDSIRDVIAFPKTQQARCLLTGAPSSVEAKQLKELHVASTYQP
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA