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The map label for this gene is menC [H]

Identifier: 86608214

GI number: 86608214

Start: 749863

End: 750927

Strand: Reverse

Name: menC [H]

Synonym: CYB_0729

Alternate gene names: 86608214

Gene position: 750927-749863 (Counterclockwise)

Preceding gene: 86608215

Following gene: 86608213

Centisome position: 24.65

GC content: 60.94

Gene sequence:

>1065_bases
GTGCCGCTTGGGCGGCTGGAAAAGCGGTTTTCCTTTGCGTTTTGCTCCTACTGGCGTCCCTTTCGGCGGCCCCTGCGTAC
CCACCACGGACTGTGGTCCGTGCGCGAAGGGATCCTGATCCGACTTACAGATCGGGAGACAGGCTGTCAGGGATATGGGG
AAATTGCTCCCATCCCTTGGTTTGGCAGCGAAACCCTGGAGCAGGCTCTGGCGTTTTGTCGGCAGCTGCCCCCTCTTTTG
TCGGAGGCGTATATTTTGGGGATCCCAGAAGCACTGCCGGCCTGCCGGTTTGGGTTGGAAGGCGCTTGGCTGGCCTGTCG
GGATCCCGATTGGTTGAACAAGGATCTCTCTCTACTCTCTTTCTGTGAACTTTTGGGGGAGACCCTGCCGCCGGAATCTT
ACAAGGACTCCTACAAGGACTCCGTCCCACTCACGCGGTCGGTGTACAAGCTCAAGGTGGGGAGGGATCCCATGCAGCAG
GAGTTGGAGAAGCTGGAGCAATGGCTGGAGCGCTTGCCGCCGGGATCCCGTCTGCGTTTGGATGCCAATGGGGGATTATC
GCTTGCGGAGGCCCACCGGTGGCTGATGGTTTGTGATCGGCTTAACCAGGACTCGCCGGGCAAGATCGAGTTTTTGGAGC
AGCCTCTGCCGCCGGATCAGCACTCCCATCTGGTGGAGCTCAGCCGCCAGTACCAGACCCCCATTGCTTTGGATGAATCG
GTGGCCTGTTTGGAACAGTTGCAAGCCGTCCATCGCTCAGGATGGACAGGGATCCTGGTGGTGAAGCCATCTTTGGTGGG
CTCCTGCATCGCGCTGCGGGAGTATCTCAGCCGACATCCCGGCCTGGATCTGGTTTTTTCTTCTGCGCTGGAGACTGCCA
TCGGCGCTTGGCATGGACTGGCCTGGGCGGGATCCCTGCAAGCCAAAACCGCCTCTCCCCGGGCCGTGGGATGGGGGGTA
GGGGAGTTTTTCCAGGAAGGGGATCCCCTGACCTTGACCCAGCTCTCAGCCCAGGAGCGGGCTGCCCTCATGCAGGCGGT
GTGGGAGCGCTACAGCCGGCCCTAG

Upstream 100 bases:

>100_bases
TGAGAAAACTGGCGTTTTTCCTTTCTTTATCTTGCTTGAGCTTTTTGTGGCTGGTAGGCACAGCAGATCATCTGCAGGGG
ATACCCAAAAAGAGGGATCC

Downstream 100 bases:

>100_bases
ACTGCGGCGGCCTGTTGTTTGGCGTATTCCTGCCGCAGATAGGCCTGGATAAAATGCATCAGCTCCTCCGGCTCGCCGTT
CATAAAGGCCTCGACATTGT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MPLGRLEKRFSFAFCSYWRPFRRPLRTHHGLWSVREGILIRLTDRETGCQGYGEIAPIPWFGSETLEQALAFCRQLPPLL
SEAYILGIPEALPACRFGLEGAWLACRDPDWLNKDLSLLSFCELLGETLPPESYKDSYKDSVPLTRSVYKLKVGRDPMQQ
ELEKLEQWLERLPPGSRLRLDANGGLSLAEAHRWLMVCDRLNQDSPGKIEFLEQPLPPDQHSHLVELSRQYQTPIALDES
VACLEQLQAVHRSGWTGILVVKPSLVGSCIALREYLSRHPGLDLVFSSALETAIGAWHGLAWAGSLQAKTASPRAVGWGV
GEFFQEGDPLTLTQLSAQERAALMQAVWERYSRP

Sequences:

>Translated_354_residues
MPLGRLEKRFSFAFCSYWRPFRRPLRTHHGLWSVREGILIRLTDRETGCQGYGEIAPIPWFGSETLEQALAFCRQLPPLL
SEAYILGIPEALPACRFGLEGAWLACRDPDWLNKDLSLLSFCELLGETLPPESYKDSYKDSVPLTRSVYKLKVGRDPMQQ
ELEKLEQWLERLPPGSRLRLDANGGLSLAEAHRWLMVCDRLNQDSPGKIEFLEQPLPPDQHSHLVELSRQYQTPIALDES
VACLEQLQAVHRSGWTGILVVKPSLVGSCIALREYLSRHPGLDLVFSSALETAIGAWHGLAWAGSLQAKTASPRAVGWGV
GEFFQEGDPLTLTQLSAQERAALMQAVWERYSRP
>Mature_353_residues
PLGRLEKRFSFAFCSYWRPFRRPLRTHHGLWSVREGILIRLTDRETGCQGYGEIAPIPWFGSETLEQALAFCRQLPPLLS
EAYILGIPEALPACRFGLEGAWLACRDPDWLNKDLSLLSFCELLGETLPPESYKDSYKDSVPLTRSVYKLKVGRDPMQQE
LEKLEQWLERLPPGSRLRLDANGGLSLAEAHRWLMVCDRLNQDSPGKIEFLEQPLPPDQHSHLVELSRQYQTPIALDESV
ACLEQLQAVHRSGWTGILVVKPSLVGSCIALREYLSRHPGLDLVFSSALETAIGAWHGLAWAGSLQAKTASPRAVGWGVG
EFFQEGDPLTLTQLSAQERAALMQAVWERYSRP

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 39874; Mature: 39743

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLGRLEKRFSFAFCSYWRPFRRPLRTHHGLWSVREGILIRLTDRETGCQGYGEIAPIPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
FGSETLEQALAFCRQLPPLLSEAYILGIPEALPACRFGLEGAWLACRDPDWLNKDLSLLS
CCHHHHHHHHHHHHHCCHHHHCHHEEECCHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH
FCELLGETLPPESYKDSYKDSVPLTRSVYKLKVGRDPMQQELEKLEQWLERLPPGSRLRL
HHHHHHCCCCCCHHHHHHCCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCEEEE
DANGGLSLAEAHRWLMVCDRLNQDSPGKIEFLEQPLPPDQHSHLVELSRQYQTPIALDES
ECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHH
VACLEQLQAVHRSGWTGILVVKPSLVGSCIALREYLSRHPGLDLVFSSALETAIGAWHGL
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AWAGSLQAKTASPRAVGWGVGEFFQEGDPLTLTQLSAQERAALMQAVWERYSRP
HHCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLGRLEKRFSFAFCSYWRPFRRPLRTHHGLWSVREGILIRLTDRETGCQGYGEIAPIPW
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
FGSETLEQALAFCRQLPPLLSEAYILGIPEALPACRFGLEGAWLACRDPDWLNKDLSLLS
CCHHHHHHHHHHHHHCCHHHHCHHEEECCHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH
FCELLGETLPPESYKDSYKDSVPLTRSVYKLKVGRDPMQQELEKLEQWLERLPPGSRLRL
HHHHHHCCCCCCHHHHHHCCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCEEEE
DANGGLSLAEAHRWLMVCDRLNQDSPGKIEFLEQPLPPDQHSHLVELSRQYQTPIALDES
ECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHH
VACLEQLQAVHRSGWTGILVVKPSLVGSCIALREYLSRHPGLDLVFSSALETAIGAWHGL
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AWAGSLQAKTASPRAVGWGVGEFFQEGDPLTLTQLSAQERAALMQAVWERYSRP
HHCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]