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The map label for this gene is fbp [H]

Identifier: 86607892

GI number: 86607892

Start: 409537

End: 410001

Strand: Reverse

Name: fbp [H]

Synonym: CYB_0395

Alternate gene names: 86607892

Gene position: 410001-409537 (Counterclockwise)

Preceding gene: 86607893

Following gene: 86607891

Centisome position: 13.46

GC content: 61.08

Gene sequence:

>465_bases
ATGAAACGGGTGCTGCTGTTGGTGCTGGGCTTGCTGTGGCTTGGGGTGTGGGGCGGCCAGCCGGCCATAGCTCTATCGCG
GGCCAAAGACAATCCGGTGGTGAGCGTGCAATCCCCAGCCAAGGACTTCATCACCACCGAGTCGGGATTGCAATACTACG
ATATTGCTCAAGGCAGTGGGCCTTCGCCTCAGCCGGGGCAAACGGTGGTGGTCAACTACGTGGGCAAGCTACAGGATGGC
ACCATCTTCGATAGCTCCTACAAGCGCAATCAGCCTTTTGTCTTCACCTACGGAGTAGGGCAGGTGATCCGTGGCTGGGA
GGAAGGGCTGGCCACCATGCGGGTGGGGGGCAAGCGCTACTTGCGCATTCCGCCGGAGTTGGCCTATGGCAGCCGCGGGG
CAGGCGGGGTGATCCCCCCCAATGCCACCTTGGATTTTGAAGTGGAGCTCCTGGCCATCCAGTAG

Upstream 100 bases:

>100_bases
ACCAGGGTCAGATTATCGAATTTGCCGAACTGAAAGGCTGACGGGATCCCCTAAGATTGTTAAAGGAAAGCCAAAAGTCG
GCGGTGGGGAGACGCCAACG

Downstream 100 bases:

>100_bases
ATTCAGATCTTGCAGAGACCGAATATCCAAGCGGCATTGGGCTTGTGCAGGAACTCCCTTCCCCGGAACTGTCTTCTTCT
TGGCGGCCCAGTTCTCTGGC

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKRVLLLVLGLLWLGVWGGQPAIALSRAKDNPVVSVQSPAKDFITTESGLQYYDIAQGSGPSPQPGQTVVVNYVGKLQDG
TIFDSSYKRNQPFVFTYGVGQVIRGWEEGLATMRVGGKRYLRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ

Sequences:

>Translated_154_residues
MKRVLLLVLGLLWLGVWGGQPAIALSRAKDNPVVSVQSPAKDFITTESGLQYYDIAQGSGPSPQPGQTVVVNYVGKLQDG
TIFDSSYKRNQPFVFTYGVGQVIRGWEEGLATMRVGGKRYLRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ
>Mature_154_residues
MKRVLLLVLGLLWLGVWGGQPAIALSRAKDNPVVSVQSPAKDFITTESGLQYYDIAQGSGPSPQPGQTVVVNYVGKLQDG
TIFDSSYKRNQPFVFTYGVGQVIRGWEEGLATMRVGGKRYLRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=107, Percent_Identity=53.2710280373832, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4503725, Length=107, Percent_Identity=53.2710280373832, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4758380, Length=107, Percent_Identity=50.4672897196262, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI206725530, Length=91, Percent_Identity=58.2417582417582, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI17149844, Length=91, Percent_Identity=58.2417582417582, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI17149842, Length=91, Percent_Identity=58.2417582417582, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI224809329, Length=133, Percent_Identity=45.1127819548872, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI224809327, Length=133, Percent_Identity=45.1127819548872, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI4758384, Length=133, Percent_Identity=45.1127819548872, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI224809331, Length=129, Percent_Identity=43.4108527131783, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI4503727, Length=99, Percent_Identity=50.5050505050505, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI4503729, Length=99, Percent_Identity=48.4848484848485, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI33469985, Length=90, Percent_Identity=46.6666666666667, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI192448443, Length=104, Percent_Identity=43.2692307692308, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI8923659, Length=92, Percent_Identity=46.7391304347826, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI7706131, Length=116, Percent_Identity=39.6551724137931, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI206725547, Length=155, Percent_Identity=31.6129032258064, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI31317231, Length=125, Percent_Identity=36.8, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=35.8490566037736, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI87082390, Length=109, Percent_Identity=56.8807339449541, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI1789745, Length=110, Percent_Identity=50.9090909090909, Blast_Score=93, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17540882, Length=98, Percent_Identity=48.9795918367347, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71993519, Length=93, Percent_Identity=50.5376344086022, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561778, Length=114, Percent_Identity=39.4736842105263, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17561782, Length=89, Percent_Identity=48.314606741573, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17506169, Length=109, Percent_Identity=34.8623853211009, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17506167, Length=109, Percent_Identity=34.8623853211009, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17561780, Length=108, Percent_Identity=37.962962962963, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320727, Length=92, Percent_Identity=55.4347826086957, Blast_Score=103, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324194, Length=109, Percent_Identity=45.8715596330275, Blast_Score=94, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6323482, Length=108, Percent_Identity=43.5185185185185, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323566, Length=108, Percent_Identity=40.7407407407407, Blast_Score=81, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=56.0747663551402, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281363946, Length=89, Percent_Identity=58.4269662921348, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17352457, Length=89, Percent_Identity=58.4269662921348, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583150, Length=98, Percent_Identity=46.9387755102041, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647110, Length=120, Percent_Identity=47.5, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356629, Length=90, Percent_Identity=57.7777777777778, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16652; Mature: 16652

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLLLVLGLLWLGVWGGQPAIALSRAKDNPVVSVQSPAKDFITTESGLQYYDIAQGSG
CHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCHHEECCCCCEEEEECCCCC
PSPQPGQTVVVNYVGKLQDGTIFDSSYKRNQPFVFTYGVGQVIRGWEEGLATMRVGGKRY
CCCCCCCEEEEEEECCCCCCEEECCCCCCCCCEEEEECHHHHHHHHHHCHHEEEECCEEE
LRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ
EECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure
MKRVLLLVLGLLWLGVWGGQPAIALSRAKDNPVVSVQSPAKDFITTESGLQYYDIAQGSG
CHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCHHEECCCCCEEEEECCCCC
PSPQPGQTVVVNYVGKLQDGTIFDSSYKRNQPFVFTYGVGQVIRGWEEGLATMRVGGKRY
CCCCCCCEEEEEEECCCCCCEEECCCCCCCCCEEEEECHHHHHHHHHHCHHEEEECCEEE
LRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ
EECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]