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The map label for this gene is codA [H]

Identifier: 86607889

GI number: 86607889

Start: 407105

End: 408379

Strand: Direct

Name: codA [H]

Synonym: CYB_0393

Alternate gene names: 86607889

Gene position: 407105-408379 (Clockwise)

Preceding gene: 86607880

Following gene: 86607894

Centisome position: 13.36

GC content: 63.14

Gene sequence:

>1275_bases
ATGGATCTCATTTTGCGCCGGGCCAATTTGCCGGATGGCCGCAAGGGAATCGATATCGGTATCCAGGGGGATCGCATTGT
GGCTCTGGAAAGCAACTTACAAGCCACTGCCCCCCAAGAAATTGATGTCACCAACCGCTTGGTGTCGCCCCCCTTTGTGG
ATGCCCACTTTCACCTGGATGCCACCCTTACCTACGGGATCCCGCGCGTCAACCAATCGGGCACCTTGCTGGAAGGGATC
GCCCTCTGGGGAGAGTTGAAGCCACTGCTAACTCCGGAGGCGGTCATCGAGCGGGCTCTAACCTACTGCGACTGGGCAGT
GGCGCGCGGGATCTTAGCCATCCGCGCCCATGTGGACGTGTGCGATCCCAACCTGGTGGCGGTGCGGGCCTTGCTGGAGG
TCAAGCAAAAAGTATCCCCCTACCTGGATTTGCAACTGGTGGCCTTTCCCCAAGATGGCTACTACCGCTCGCCGGGGGCG
GTGCAGCTTTTGGAGAAGGCTCTGGATTTGGGGGTGGAGGTGGTGGGTGGGATCCCCCACTTCGAGCGGACGATGGCCGA
AGGAGCCGCTTCAGTGCGGGCTCTGTGCGAGATTGCAGCCGCGCGGGGCCTGCGGGTGGATCTGCACTGCGACGAAACAG
ACGACCCCCTCTCCCGCCACGTGGAGACCCTGGCCTACGAGACGCTGCGGCTGGGCCTGCAGGGGCGGGTGGCCGCCTCC
CACCTCACCTCGATGCACTCAATGGACAACGCCTACGTGAGCAAACTCATTCCCCTGATGGCCGAAGCAGAGCTGGGGGT
GATCGCCAACCCGCTGGTGAACCTGGTGCTGCAGGGCCGCCACGATACCTATCCCAAGCGGCGGGGGCTGACGCGGGTGC
CGGAGCTGATGGCCGCCGGGCTGACGGTGGCTTTTGGCCAGGACTGTGTGATGGATCCCTGGTACCCTCTGGGCAGCGGC
AACATGCTGGAAGTGGCCCACATGGCCGTCCACGCTGCCCAGATGACAGGCTATGAGCAGATGCGGCAGTGCTTCTTGGC
GGTTACGGAAAACCCGGCCCGCATTCTGGGGTTAGAAGGCTACGGACTAGAACCCGGCTGCTATGCCGACTTGGTGGTGC
TCCAGGCTGCTGATGCCGTCGAAGCTATTCGCCTGAAACCAGCTTGCCTGTATGTCTTCCGCCGGGGACGGCTGATCGCC
CAAACCCCGCCGGTGGTTGCCCAGCTCCATTTGCCGGGGCGCTCGGCCCAGGTGGACTTCACCCGCCAGCTTTAA

Upstream 100 bases:

>100_bases
CTTTGAGGTAATTTAAGACATCTTTATCTGATTTGGCCTATCATTCAGTCAACTGTAGTTGCTTCTTTCCATCCTAAGTT
CAAACAAATAGCCACAACAT

Downstream 100 bases:

>100_bases
CGGCGCACGGTGCCGCTGAAGCCGCTGGCTTTGAACTGCTCCATAGTCAGAGGCAGCGGGCTGGTCACGGGCACGGAGAT
GCGAATGGAGAAGGGGCTTT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDLILRRANLPDGRKGIDIGIQGDRIVALESNLQATAPQEIDVTNRLVSPPFVDAHFHLDATLTYGIPRVNQSGTLLEGI
ALWGELKPLLTPEAVIERALTYCDWAVARGILAIRAHVDVCDPNLVAVRALLEVKQKVSPYLDLQLVAFPQDGYYRSPGA
VQLLEKALDLGVEVVGGIPHFERTMAEGAASVRALCEIAAARGLRVDLHCDETDDPLSRHVETLAYETLRLGLQGRVAAS
HLTSMHSMDNAYVSKLIPLMAEAELGVIANPLVNLVLQGRHDTYPKRRGLTRVPELMAAGLTVAFGQDCVMDPWYPLGSG
NMLEVAHMAVHAAQMTGYEQMRQCFLAVTENPARILGLEGYGLEPGCYADLVVLQAADAVEAIRLKPACLYVFRRGRLIA
QTPPVVAQLHLPGRSAQVDFTRQL

Sequences:

>Translated_424_residues
MDLILRRANLPDGRKGIDIGIQGDRIVALESNLQATAPQEIDVTNRLVSPPFVDAHFHLDATLTYGIPRVNQSGTLLEGI
ALWGELKPLLTPEAVIERALTYCDWAVARGILAIRAHVDVCDPNLVAVRALLEVKQKVSPYLDLQLVAFPQDGYYRSPGA
VQLLEKALDLGVEVVGGIPHFERTMAEGAASVRALCEIAAARGLRVDLHCDETDDPLSRHVETLAYETLRLGLQGRVAAS
HLTSMHSMDNAYVSKLIPLMAEAELGVIANPLVNLVLQGRHDTYPKRRGLTRVPELMAAGLTVAFGQDCVMDPWYPLGSG
NMLEVAHMAVHAAQMTGYEQMRQCFLAVTENPARILGLEGYGLEPGCYADLVVLQAADAVEAIRLKPACLYVFRRGRLIA
QTPPVVAQLHLPGRSAQVDFTRQL
>Mature_424_residues
MDLILRRANLPDGRKGIDIGIQGDRIVALESNLQATAPQEIDVTNRLVSPPFVDAHFHLDATLTYGIPRVNQSGTLLEGI
ALWGELKPLLTPEAVIERALTYCDWAVARGILAIRAHVDVCDPNLVAVRALLEVKQKVSPYLDLQLVAFPQDGYYRSPGA
VQLLEKALDLGVEVVGGIPHFERTMAEGAASVRALCEIAAARGLRVDLHCDETDDPLSRHVETLAYETLRLGLQGRVAAS
HLTSMHSMDNAYVSKLIPLMAEAELGVIANPLVNLVLQGRHDTYPKRRGLTRVPELMAAGLTVAFGQDCVMDPWYPLGSG
NMLEVAHMAVHAAQMTGYEQMRQCFLAVTENPARILGLEGYGLEPGCYADLVVLQAADAVEAIRLKPACLYVFRRGRLIA
QTPPVVAQLHLPGRSAQVDFTRQL

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=419, Percent_Identity=45.5847255369928, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1786517, Length=404, Percent_Identity=27.7227722772277, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46264; Mature: 46264

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLILRRANLPDGRKGIDIGIQGDRIVALESNLQATAPQEIDVTNRLVSPPFVDAHFHLD
CCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHCCCCCEEEEEEEEE
ATLTYGIPRVNQSGTLLEGIALWGELKPLLTPEAVIERALTYCDWAVARGILAIRAHVDV
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEEC
CDPNLVAVRALLEVKQKVSPYLDLQLVAFPQDGYYRSPGAVQLLEKALDLGVEVVGGIPH
CCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHEECCCCH
FERTMAEGAASVRALCEIAAARGLRVDLHCDETDDPLSRHVETLAYETLRLGLQGRVAAS
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
HLTSMHSMDNAYVSKLIPLMAEAELGVIANPLVNLVLQGRHDTYPKRRGLTRVPELMAAG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCC
LTVAFGQDCVMDPWYPLGSGNMLEVAHMAVHAAQMTGYEQMRQCFLAVTENPARILGLEG
CEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECC
YGLEPGCYADLVVLQAADAVEAIRLKPACLYVFRRGRLIAQTPPVVAQLHLPGRSAQVDF
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCC
TRQL
CCCC
>Mature Secondary Structure
MDLILRRANLPDGRKGIDIGIQGDRIVALESNLQATAPQEIDVTNRLVSPPFVDAHFHLD
CCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHCCCCCEEEEEEEEE
ATLTYGIPRVNQSGTLLEGIALWGELKPLLTPEAVIERALTYCDWAVARGILAIRAHVDV
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEEC
CDPNLVAVRALLEVKQKVSPYLDLQLVAFPQDGYYRSPGAVQLLEKALDLGVEVVGGIPH
CCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHEECCCCH
FERTMAEGAASVRALCEIAAARGLRVDLHCDETDDPLSRHVETLAYETLRLGLQGRVAAS
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
HLTSMHSMDNAYVSKLIPLMAEAELGVIANPLVNLVLQGRHDTYPKRRGLTRVPELMAAG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCC
LTVAFGQDCVMDPWYPLGSGNMLEVAHMAVHAAQMTGYEQMRQCFLAVTENPARILGLEG
CEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECC
YGLEPGCYADLVVLQAADAVEAIRLKPACLYVFRRGRLIAQTPPVVAQLHLPGRSAQVDF
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCC
TRQL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]