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The map label for this gene is ffh [H]

Identifier: 86607761

GI number: 86607761

Start: 276639

End: 278102

Strand: Reverse

Name: ffh [H]

Synonym: CYB_0262

Alternate gene names: 86607761

Gene position: 278102-276639 (Counterclockwise)

Preceding gene: 86607763

Following gene: 86607760

Centisome position: 9.13

GC content: 60.52

Gene sequence:

>1464_bases
ATGTTTGATGCCCTCTCCGAGAAGTTGGAATTGGCCTGGAGAAAGCTGCGCGGCCAGGACAAGATCACCGAAACCAACAT
TCAAGAAGCTCTGCGGGAGGTGCGGCGAGCCCTGCTGGATGCGGATGTCAACTTGCAGGTGGTGAAGCAGTTCATCGAGG
ATGTGCGGGAAGCTGCCCTGGGATCCGAGGTCATCCTGGGGGTGACGCCGGATCAGCAGTTCATCAAGATTGTCCACGAC
GAGCTGGTGAAGGTGATGGGAGAAGCCAACGTGCCCATTGCCCAAGCGGAGCAGCCTCCCACCATTGTCCTCATGGCCGG
TTTGCAGGGATCCGGGAAAACCACCACCTGCGCCAAGTTGGCTTTGTACTTGCGCAAGCAGGGCAAGAAGTCCCTGATGG
TGGCCGGAGACATCTACCGTCCGGCGGCCATCGACCAGCTCAAGACGCTGGGCCAGCAAATTCAGATCCCCGTTTTCGAC
CTGGGCAAAGCAGATCCCGTCGAGATTGCCCGGCAGGGGGTGGAGACGGCCCGGCAGCAGGGCTACGACTACGTGATTTT
GGACACTGCCGGTCGTTTGCAGATTGACCTGGAGATGATGGCGGAGCTGGAGCGGATCAAGGCGGCGGTGCAGCCCCACG
AGATCCTGCTGGTGGTGGATGCCATGATCGGCCAAGAGGCAGCCAGCCTTACCCGAGCCTTCCACGAGCGCTTGGGCATC
ACTGGGGCCATTCTCACCAAGCTGGATGGGGACACCCGCGGTGGGGCCGCCCTTTCCATTCGCCAAGTGTCCGGTCAGCC
CATCAAGTTCATCGGTGTTGGCGAAAAGGTGGAAGCGCTGGATCCCTTCTACCCGGATCGCATGGCCTCCCGCATTCTGG
GGATGGGGGATATCCTCAGCTTGGTGGAAAAAGCTCAAGAGGAAATCGACCTGGGAGATGCCGCCAGCATGGCGGAGAAG
ATGATGACTGCCCAGTTTGATTTCACCGATTTCCTCAAGCAGATGCGCCTAATTAAACGCATGGGATCCTTGGCAGGGCT
GCTGAGACTGATGCCGGGGATGGGCAAAATCAGCGAGGAACAACTGCAAAAGGGACAAGACCAACTGGCCCGCGCCGAAG
CCATGATCAACTCCATGACCCCCGAAGAGCGGCGCAACCCGGATCTGTTGGCCCGCAGCGTCAGCCGCAAACGACGGGTG
GCCCGCGGATCTGGCCACAAGCTGGAGGATGTCAGCCGACTGGTCAGTGATTTTCAACGCATGCGCGACATGATGCGCAA
CATGGGCATGGGTGGCGGTTTTCCCGGTATGGGTTGGGGGGGTGGGCGTACCTCTCTTCCCGGCGGGGATCCCAGTTGGC
GCGGACGTTCAACGGCCTCTCCCTCTCGGCAACAGCCCAGCCGCAAGCCGGGCAAAGGTGGGGGTAAAAAAGGGGGCGGC
AACCGCGGATTTGGGGGCAAGTAG

Upstream 100 bases:

>100_bases
CCGGGATGGTCTCCTGGGTGGGGATCCCCAAGATGGAGTCGCCCCGATTCGACTATGGTAGGAAATGCCCCCAAAGCGCC
TGACAGGATCCACAGTACCC

Downstream 100 bases:

>100_bases
GATAGGACTATGCCCTTCCACGTTGTTTTGGTTGCCCCAGAGATCCCGGCCAATACGGGGAATATCGCCCGCACCTGTGC
AGCCACCGATACGCCTCTCC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MFDALSEKLELAWRKLRGQDKITETNIQEALREVRRALLDADVNLQVVKQFIEDVREAALGSEVILGVTPDQQFIKIVHD
ELVKVMGEANVPIAQAEQPPTIVLMAGLQGSGKTTTCAKLALYLRKQGKKSLMVAGDIYRPAAIDQLKTLGQQIQIPVFD
LGKADPVEIARQGVETARQQGYDYVILDTAGRLQIDLEMMAELERIKAAVQPHEILLVVDAMIGQEAASLTRAFHERLGI
TGAILTKLDGDTRGGAALSIRQVSGQPIKFIGVGEKVEALDPFYPDRMASRILGMGDILSLVEKAQEEIDLGDAASMAEK
MMTAQFDFTDFLKQMRLIKRMGSLAGLLRLMPGMGKISEEQLQKGQDQLARAEAMINSMTPEERRNPDLLARSVSRKRRV
ARGSGHKLEDVSRLVSDFQRMRDMMRNMGMGGGFPGMGWGGGRTSLPGGDPSWRGRSTASPSRQQPSRKPGKGGGKKGGG
NRGFGGK

Sequences:

>Translated_487_residues
MFDALSEKLELAWRKLRGQDKITETNIQEALREVRRALLDADVNLQVVKQFIEDVREAALGSEVILGVTPDQQFIKIVHD
ELVKVMGEANVPIAQAEQPPTIVLMAGLQGSGKTTTCAKLALYLRKQGKKSLMVAGDIYRPAAIDQLKTLGQQIQIPVFD
LGKADPVEIARQGVETARQQGYDYVILDTAGRLQIDLEMMAELERIKAAVQPHEILLVVDAMIGQEAASLTRAFHERLGI
TGAILTKLDGDTRGGAALSIRQVSGQPIKFIGVGEKVEALDPFYPDRMASRILGMGDILSLVEKAQEEIDLGDAASMAEK
MMTAQFDFTDFLKQMRLIKRMGSLAGLLRLMPGMGKISEEQLQKGQDQLARAEAMINSMTPEERRNPDLLARSVSRKRRV
ARGSGHKLEDVSRLVSDFQRMRDMMRNMGMGGGFPGMGWGGGRTSLPGGDPSWRGRSTASPSRQQPSRKPGKGGGKKGGG
NRGFGGK
>Mature_487_residues
MFDALSEKLELAWRKLRGQDKITETNIQEALREVRRALLDADVNLQVVKQFIEDVREAALGSEVILGVTPDQQFIKIVHD
ELVKVMGEANVPIAQAEQPPTIVLMAGLQGSGKTTTCAKLALYLRKQGKKSLMVAGDIYRPAAIDQLKTLGQQIQIPVFD
LGKADPVEIARQGVETARQQGYDYVILDTAGRLQIDLEMMAELERIKAAVQPHEILLVVDAMIGQEAASLTRAFHERLGI
TGAILTKLDGDTRGGAALSIRQVSGQPIKFIGVGEKVEALDPFYPDRMASRILGMGDILSLVEKAQEEIDLGDAASMAEK
MMTAQFDFTDFLKQMRLIKRMGSLAGLLRLMPGMGKISEEQLQKGQDQLARAEAMINSMTPEERRNPDLLARSVSRKRRV
ARGSGHKLEDVSRLVSDFQRMRDMMRNMGMGGGFPGMGWGGGRTSLPGGDPSWRGRSTASPSRQQPSRKPGKGGGKKGGG
NRGFGGK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=447, Percent_Identity=34.675615212528, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI226371618, Length=370, Percent_Identity=34.3243243243243, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI89061728, Length=164, Percent_Identity=36.5853658536585, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295424842, Length=292, Percent_Identity=27.3972602739726, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI23308697, Length=292, Percent_Identity=27.3972602739726, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1788963, Length=427, Percent_Identity=50.3512880562061, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789874, Length=269, Percent_Identity=34.9442379182156, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17539958, Length=442, Percent_Identity=32.8054298642534, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI193206261, Length=204, Percent_Identity=32.3529411764706, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=480, Percent_Identity=32.2916666666667, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6320498, Length=213, Percent_Identity=27.6995305164319, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17647949, Length=434, Percent_Identity=33.8709677419355, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24641198, Length=295, Percent_Identity=24.406779661017, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53219; Mature: 53219

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDALSEKLELAWRKLRGQDKITETNIQEALREVRRALLDADVNLQVVKQFIEDVREAAL
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
GSEVILGVTPDQQFIKIVHDELVKVMGEANVPIAQAEQPPTIVLMAGLQGSGKTTTCAKL
CCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHH
ALYLRKQGKKSLMVAGDIYRPAAIDQLKTLGQQIQIPVFDLGKADPVEIARQGVETARQQ
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHC
GYDYVILDTAGRLQIDLEMMAELERIKAAVQPHEILLVVDAMIGQEAASLTRAFHERLGI
CCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
TGAILTKLDGDTRGGAALSIRQVSGQPIKFIGVGEKVEALDPFYPDRMASRILGMGDILS
CHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHCCCCCHHHHHHHHHCHHHHHH
LVEKAQEEIDLGDAASMAEKMMTAQFDFTDFLKQMRLIKRMGSLAGLLRLMPGMGKISEE
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
QLQKGQDQLARAEAMINSMTPEERRNPDLLARSVSRKRRVARGSGHKLEDVSRLVSDFQR
HHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MRDMMRNMGMGGGFPGMGWGGGRTSLPGGDPSWRGRSTASPSRQQPSRKPGKGGGKKGGG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NRGFGGK
CCCCCCC
>Mature Secondary Structure
MFDALSEKLELAWRKLRGQDKITETNIQEALREVRRALLDADVNLQVVKQFIEDVREAAL
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
GSEVILGVTPDQQFIKIVHDELVKVMGEANVPIAQAEQPPTIVLMAGLQGSGKTTTCAKL
CCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHH
ALYLRKQGKKSLMVAGDIYRPAAIDQLKTLGQQIQIPVFDLGKADPVEIARQGVETARQQ
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHC
GYDYVILDTAGRLQIDLEMMAELERIKAAVQPHEILLVVDAMIGQEAASLTRAFHERLGI
CCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
TGAILTKLDGDTRGGAALSIRQVSGQPIKFIGVGEKVEALDPFYPDRMASRILGMGDILS
CHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHCCCCCHHHHHHHHHCHHHHHH
LVEKAQEEIDLGDAASMAEKMMTAQFDFTDFLKQMRLIKRMGSLAGLLRLMPGMGKISEE
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
QLQKGQDQLARAEAMINSMTPEERRNPDLLARSVSRKRRVARGSGHKLEDVSRLVSDFQR
HHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MRDMMRNMGMGGGFPGMGWGGGRTSLPGGDPSWRGRSTASPSRQQPSRKPGKGGGKKGGG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NRGFGGK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]