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The map label for this gene is cfa [H]

Identifier: 86607644

GI number: 86607644

Start: 159250

End: 160389

Strand: Direct

Name: cfa [H]

Synonym: CYB_0142

Alternate gene names: 86607644

Gene position: 159250-160389 (Clockwise)

Preceding gene: 86607643

Following gene: 86607645

Centisome position: 5.23

GC content: 57.02

Gene sequence:

>1140_bases
ATGGGGAAAGGACTCAACAGCTTGCGCTGGCTGGCGCGTCAGTATGCGCTTCGAGTTCTGGATGCTGCCGGTATAACCCT
CAATGGCTCGCAACCTTGGGATATTCAAGTTCACGACGAGCGGCTATATCTGCGCTGCCTGCTCTATGGATCCCTGGGCT
TTGGCGAGGCCTACATGGAGGGCTGGTGGGATTGCGAGGCCATTGATGAGTTAGTTTGTCGTCTCCTAACTGCCCAGGCA
CCGCAGCAGGTGGGTTGGCTAACTCAGCCCTTGCTTGGGTTGGACAGTTGCCTTATCAACCGCCAGCGGGGCAAGGGGGC
ATTCGTCATTGGCCAGCGCCACTACGACATTGGCAACGATCTCTATGAGGACATGCTGGATCGCCGCATGATCTACAGCT
GTGCCTATTGGGATGGGGGCGCGCAAACTCTGGATGAAGCCCAAGAAGCTAAGCTTGACCTCATTGCCCGCAAGCTGGAA
CTCCAACCCGGCATGCGGGTGCTCGACATCGGCTGTGGCTGGGGCGGCACAGCCCAGTACCTGGCCGAACGCTACGGGGT
GCAGGTTGTGGGGATTACTGTTTCCAAAGAGCAAGCCAAACTGGCCAGCGAACGCTGCCGCGGCCTGCCGGTCGAGATTC
GGTTAGAAGACTATCGCCAGACCCAGGGAAAGTTTGATCGCATCCTTTCTGTCGGCATGTTTGAACATGTTGGCTACCGA
AACTACCGAACGTTTATGCAGGTAGCCCGCCGCTTGTTGAACGACAATGGCTTGTTTCTTCTGCACACCATCGGCAGCAA
CGTGGCCTACCAGGGGCGGGATCCCTGGATTGAGCGCTACATTTTCCCCAACTCGATGCTGCCCTCGCCTCATCTGATTA
CTGCAGCCTTTGAGGGCTTATTTGTGCTGGAAGACTGGCACAATTTTGGGATCAATTACGTGGCCACCTTAAAAGCCTGG
CACGCCAATTTCGAGCAGGCATGGCCAAAATTAGCCGACCGCTACGATGAGCGCTTTCGCCGCATGTGGCGGCTCTATCT
CCTGATGAGTGCCGGTAGCTTCAAGGCCCGGGCCAGCCAACTTTGGCAACTGGTCCTCTCACCACGGGGAGTAAGTGGCG
GCTATCGCTCGCTTCGGTAA

Upstream 100 bases:

>100_bases
TCGGGGGGATCCCTAGAAATTGGAAACAACTTGTTGGATCCCTTGCCACCTTGGGGTGTATTTGTTGAGTCAGTTTCCCT
GCAGTGAGGGATCCCTAGGG

Downstream 100 bases:

>100_bases
CGACAGTCCCAAAAGTTTGCAGGTGCCCCTGCGCCCTCGCTGAGTGGGGGTGTTATGATGAGTTTGATTATCATTCTCAC
TCTAGACAGGCTGAGGGATG

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MGKGLNSLRWLARQYALRVLDAAGITLNGSQPWDIQVHDERLYLRCLLYGSLGFGEAYMEGWWDCEAIDELVCRLLTAQA
PQQVGWLTQPLLGLDSCLINRQRGKGAFVIGQRHYDIGNDLYEDMLDRRMIYSCAYWDGGAQTLDEAQEAKLDLIARKLE
LQPGMRVLDIGCGWGGTAQYLAERYGVQVVGITVSKEQAKLASERCRGLPVEIRLEDYRQTQGKFDRILSVGMFEHVGYR
NYRTFMQVARRLLNDNGLFLLHTIGSNVAYQGRDPWIERYIFPNSMLPSPHLITAAFEGLFVLEDWHNFGINYVATLKAW
HANFEQAWPKLADRYDERFRRMWRLYLLMSAGSFKARASQLWQLVLSPRGVSGGYRSLR

Sequences:

>Translated_379_residues
MGKGLNSLRWLARQYALRVLDAAGITLNGSQPWDIQVHDERLYLRCLLYGSLGFGEAYMEGWWDCEAIDELVCRLLTAQA
PQQVGWLTQPLLGLDSCLINRQRGKGAFVIGQRHYDIGNDLYEDMLDRRMIYSCAYWDGGAQTLDEAQEAKLDLIARKLE
LQPGMRVLDIGCGWGGTAQYLAERYGVQVVGITVSKEQAKLASERCRGLPVEIRLEDYRQTQGKFDRILSVGMFEHVGYR
NYRTFMQVARRLLNDNGLFLLHTIGSNVAYQGRDPWIERYIFPNSMLPSPHLITAAFEGLFVLEDWHNFGINYVATLKAW
HANFEQAWPKLADRYDERFRRMWRLYLLMSAGSFKARASQLWQLVLSPRGVSGGYRSLR
>Mature_378_residues
GKGLNSLRWLARQYALRVLDAAGITLNGSQPWDIQVHDERLYLRCLLYGSLGFGEAYMEGWWDCEAIDELVCRLLTAQAP
QQVGWLTQPLLGLDSCLINRQRGKGAFVIGQRHYDIGNDLYEDMLDRRMIYSCAYWDGGAQTLDEAQEAKLDLIARKLEL
QPGMRVLDIGCGWGGTAQYLAERYGVQVVGITVSKEQAKLASERCRGLPVEIRLEDYRQTQGKFDRILSVGMFEHVGYRN
YRTFMQVARRLLNDNGLFLLHTIGSNVAYQGRDPWIERYIFPNSMLPSPHLITAAFEGLFVLEDWHNFGINYVATLKAWH
ANFEQAWPKLADRYDERFRRMWRLYLLMSAGSFKARASQLWQLVLSPRGVSGGYRSLR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=365, Percent_Identity=52.3287671232877, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI133904226, Length=386, Percent_Identity=28.4974093264249, Blast_Score=138, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 43539; Mature: 43407

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGLNSLRWLARQYALRVLDAAGITLNGSQPWDIQVHDERLYLRCLLYGSLGFGEAYME
CCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEECCCEEEEHHHHCCCCCCHHHHH
GWWDCEAIDELVCRLLTAQAPQQVGWLTQPLLGLDSCLINRQRGKGAFVIGQRHYDIGND
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
LYEDMLDRRMIYSCAYWDGGAQTLDEAQEAKLDLIARKLELQPGMRVLDIGCGWGGTAQY
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
LAERYGVQVVGITVSKEQAKLASERCRGLPVEIRLEDYRQTQGKFDRILSVGMFEHVGYR
HHHHHCEEEEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCH
NYRTFMQVARRLLNDNGLFLLHTIGSNVAYQGRDPWIERYIFPNSMLPSPHLITAAFEGL
HHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCHHHHEECCCCCCCCCCHHHHHHCCE
FVLEDWHNFGINYVATLKAWHANFEQAWPKLADRYDERFRRMWRLYLLMSAGSFKARASQ
EEEECHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LWQLVLSPRGVSGGYRSLR
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GKGLNSLRWLARQYALRVLDAAGITLNGSQPWDIQVHDERLYLRCLLYGSLGFGEAYME
CCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEECCCEEEEHHHHCCCCCCHHHHH
GWWDCEAIDELVCRLLTAQAPQQVGWLTQPLLGLDSCLINRQRGKGAFVIGQRHYDIGND
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
LYEDMLDRRMIYSCAYWDGGAQTLDEAQEAKLDLIARKLELQPGMRVLDIGCGWGGTAQY
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
LAERYGVQVVGITVSKEQAKLASERCRGLPVEIRLEDYRQTQGKFDRILSVGMFEHVGYR
HHHHHCEEEEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCH
NYRTFMQVARRLLNDNGLFLLHTIGSNVAYQGRDPWIERYIFPNSMLPSPHLITAAFEGL
HHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCHHHHEECCCCCCCCCCHHHHHHCCE
FVLEDWHNFGINYVATLKAWHANFEQAWPKLADRYDERFRRMWRLYLLMSAGSFKARASQ
EEEECHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LWQLVLSPRGVSGGYRSLR
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]