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The map label for this gene is dapL [H]

Identifier: 86607573

GI number: 86607573

Start: 82505

End: 83689

Strand: Direct

Name: dapL [H]

Synonym: CYB_0071

Alternate gene names: 86607573

Gene position: 82505-83689 (Clockwise)

Preceding gene: 86607572

Following gene: 86607574

Centisome position: 2.71

GC content: 60.84

Gene sequence:

>1185_bases
ATGTCGATTCCCCTCGCCCAGCGACTTCAGCCCCTCGGCGGCAATGTGTTTGACCAAATGGATCAAGCCAAGCGAGAGGC
TCGTCGCTCTGGCCTGGATGTGATCGATCTGTCTCTGGGATCCTCCGATCTGCCCCCACCTTCAGACTCCTTGGCGGCCA
TCCAATCGGCTCTGTCGGATCCCTCTACCTATGGCTACACGCTGTTTCACGACACGGCGGACTTTCGCTCTGCCTGCGCC
AAGTGGTACAGGGGCAAGTTCGGCCTGGAGATCGATCCGGAAACAGAGGTGCTGCCGTTGATCGGATCCCAGCAGGGAAC
GGCCCTCTTGCCCCTGGCCCTGCTCAACCCCGGCGATGTTGCTTTGGTTGCGGATCCGGCCTATCCCTCTCACGTGGGCG
GGATCCATCTGGCGGGCGGGATCCCCTACTACCTGCCCCTGCGGGCGGAAAACCGCTTCTTGCCCCAGTGGGATCGGATC
CCGGAGGCAATCTGCCGGCAGGCGCGGCTGCTGGTGTTGAACTACCCCCACAACCCCACCACTGCCACCGTCACCCCGGA
GTTTTGGCAAGAAACCCTGCAGTTTTGTCAGCAGTACGACATCGTTCTGGCCCACGATTTTCCCTATGTGGACTGGCGTT
TCGACGGCCAGGTAGCCCCTTCCGCGCTGCAGGCGGATCCCGATAAAACCCGCACCATCGAGTTTTTTTCTCTTTCCAAG
TCCTATCACATGGGAGGGTTCCGGGTGGCCTACGCCATTGGCAGCCGAGAGCTGATCCGAGCCCTGCGATGGGTGAAATC
CACCATCGACTTCCACCAATACCAGGGCATTCTGCGGGGGGCAGCAGCAGCTTTGACAGTTCCCGATAGCTTTTTGCAGC
GCTGGCGGCAGGTGTACCGCGAGCGACGGGATATAGCCGTGGCGGCTCTGCACCGCATGGGTTGGCCTGTGCCTTTGCCG
GAGGCCACCATGTATCTGTGGGCGCCTTTGCCGGAGTTTTATCGCGGCTCTTCTGCCCAGTTTTGTTTGGACTTGGTGAG
AGCCACAGGGGTTGCCCTGTCTCCGGGTTCTGGCTTTGGCCCCAGTGGGGAAGGCTATGTCCGCTTTGCTTTGGTGGTCG
AGGGATCCCGTCTGGAGGAGGCGGTGGGACGGATCGAGGCGTTTTTGTCCCGGTGCATTTCCTAA

Upstream 100 bases:

>100_bases
AGCACGCGCCCAACCTCACTCTCTTCCCCCACTTCTGGCGACAATCCCTGAGGGGATCCTCAAGCTAGGATAGACCCCCC
TGCTTTGCAAGAGTTGTTGC

Downstream 100 bases:

>100_bases
ATCCCAAACATCAATCCCAAACATCGAGCATCCAGCTCTCGGTTGGTTGTGCTCGCCCACCGTCGGGCAATCTAAGTCAG
GATAAGAGTAAGAGTGTTAT

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSIPLAQRLQPLGGNVFDQMDQAKREARRSGLDVIDLSLGSSDLPPPSDSLAAIQSALSDPSTYGYTLFHDTADFRSACA
KWYRGKFGLEIDPETEVLPLIGSQQGTALLPLALLNPGDVALVADPAYPSHVGGIHLAGGIPYYLPLRAENRFLPQWDRI
PEAICRQARLLVLNYPHNPTTATVTPEFWQETLQFCQQYDIVLAHDFPYVDWRFDGQVAPSALQADPDKTRTIEFFSLSK
SYHMGGFRVAYAIGSRELIRALRWVKSTIDFHQYQGILRGAAAALTVPDSFLQRWRQVYRERRDIAVAALHRMGWPVPLP
EATMYLWAPLPEFYRGSSAQFCLDLVRATGVALSPGSGFGPSGEGYVRFALVVEGSRLEEAVGRIEAFLSRCIS

Sequences:

>Translated_394_residues
MSIPLAQRLQPLGGNVFDQMDQAKREARRSGLDVIDLSLGSSDLPPPSDSLAAIQSALSDPSTYGYTLFHDTADFRSACA
KWYRGKFGLEIDPETEVLPLIGSQQGTALLPLALLNPGDVALVADPAYPSHVGGIHLAGGIPYYLPLRAENRFLPQWDRI
PEAICRQARLLVLNYPHNPTTATVTPEFWQETLQFCQQYDIVLAHDFPYVDWRFDGQVAPSALQADPDKTRTIEFFSLSK
SYHMGGFRVAYAIGSRELIRALRWVKSTIDFHQYQGILRGAAAALTVPDSFLQRWRQVYRERRDIAVAALHRMGWPVPLP
EATMYLWAPLPEFYRGSSAQFCLDLVRATGVALSPGSGFGPSGEGYVRFALVVEGSRLEEAVGRIEAFLSRCIS
>Mature_393_residues
SIPLAQRLQPLGGNVFDQMDQAKREARRSGLDVIDLSLGSSDLPPPSDSLAAIQSALSDPSTYGYTLFHDTADFRSACAK
WYRGKFGLEIDPETEVLPLIGSQQGTALLPLALLNPGDVALVADPAYPSHVGGIHLAGGIPYYLPLRAENRFLPQWDRIP
EAICRQARLLVLNYPHNPTTATVTPEFWQETLQFCQQYDIVLAHDFPYVDWRFDGQVAPSALQADPDKTRTIEFFSLSKS
YHMGGFRVAYAIGSRELIRALRWVKSTIDFHQYQGILRGAAAALTVPDSFLQRWRQVYRERRDIAVAALHRMGWPVPLPE
ATMYLWAPLPEFYRGSSAQFCLDLVRATGVALSPGSGFGPSGEGYVRFALVVEGSRLEEAVGRIEAFLSRCIS

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=381, Percent_Identity=23.8845144356955, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI169881279, Length=381, Percent_Identity=23.8845144356955, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56713254, Length=413, Percent_Identity=20.5811138014528, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI56713256, Length=413, Percent_Identity=20.5811138014528, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=35.2480417754569, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1786816, Length=394, Percent_Identity=25.8883248730964, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=22.7390180878553, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=248, Percent_Identity=22.1774193548387, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=248, Percent_Identity=22.1774193548387, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=391, Percent_Identity=20.460358056266, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=22.4806201550388, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28573069, Length=366, Percent_Identity=22.4043715846995, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646114, Length=366, Percent_Identity=22.4043715846995, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573067, Length=366, Percent_Identity=22.4043715846995, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573065, Length=366, Percent_Identity=22.4043715846995, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43747; Mature: 43616

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPLAQRLQPLGGNVFDQMDQAKREARRSGLDVIDLSLGSSDLPPPSDSLAAIQSALSD
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCC
PSTYGYTLFHDTADFRSACAKWYRGKFGLEIDPETEVLPLIGSQQGTALLPLALLNPGDV
CCCCCEEEEECCHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCEEEEEEEECCCCE
ALVADPAYPSHVGGIHLAGGIPYYLPLRAENRFLPQWDRIPEAICRQARLLVLNYPHNPT
EEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCC
TATVTPEFWQETLQFCQQYDIVLAHDFPYVDWRFDGQVAPSALQADPDKTRTIEFFSLSK
EEEECHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCHHHCCCCCCCEEEEEEEECC
SYHMGGFRVAYAIGSRELIRALRWVKSTIDFHQYQGILRGAAAALTVPDSFLQRWRQVYR
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHH
ERRDIAVAALHRMGWPVPLPEATMYLWAPLPEFYRGSSAQFCLDLVRATGVALSPGSGFG
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHCCCCHHHHHHHHHHCCCEECCCCCCC
PSGEGYVRFALVVEGSRLEEAVGRIEAFLSRCIS
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIPLAQRLQPLGGNVFDQMDQAKREARRSGLDVIDLSLGSSDLPPPSDSLAAIQSALSD
CCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCC
PSTYGYTLFHDTADFRSACAKWYRGKFGLEIDPETEVLPLIGSQQGTALLPLALLNPGDV
CCCCCEEEEECCHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCEEEEEEEECCCCE
ALVADPAYPSHVGGIHLAGGIPYYLPLRAENRFLPQWDRIPEAICRQARLLVLNYPHNPT
EEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCC
TATVTPEFWQETLQFCQQYDIVLAHDFPYVDWRFDGQVAPSALQADPDKTRTIEFFSLSK
EEEECHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCHHHCCCCCCCEEEEEEEECC
SYHMGGFRVAYAIGSRELIRALRWVKSTIDFHQYQGILRGAAAALTVPDSFLQRWRQVYR
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHH
ERRDIAVAALHRMGWPVPLPEATMYLWAPLPEFYRGSSAQFCLDLVRATGVALSPGSGFG
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHCCCCHHHHHHHHHHCCCEECCCCCCC
PSGEGYVRFALVVEGSRLEEAVGRIEAFLSRCIS
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA