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The map label for this gene is ureC

Identifier: 86607525

GI number: 86607525

Start: 28679

End: 30397

Strand: Direct

Name: ureC

Synonym: CYB_0023

Alternate gene names: 86607525

Gene position: 28679-30397 (Clockwise)

Preceding gene: 86607518

Following gene: 86607526

Centisome position: 0.94

GC content: 60.5

Gene sequence:

>1719_bases
ATGACCCTAGAGATTCCCCGTCGCCAATACGTCAGCAACTACGGCCCCACCGTAGGGGATCGGGTGCGCCTGGCGGATAC
CGAACTGATCATCGAGGTGGAGGAGGATTTCACCACCTACGGCGAGGAGATTAAGTTTGGGGGCGGCAAAACCATCCGCG
ATGGCATGGGGCAATCGCCGACGGCCACCCGCGCCAACGGGGCCTTGGATCTGGTGATCACCAACGCCCTGATCCTGGAC
TGGTGGGGCATTGTCAAGGCGGATGTGGGCATTCGCGATGGCTACATTGTCGGCATTGGCAAAGCCGGCAACCCCAACAT
CCAAGCGGGGGTGACGCCGGGCATGGTGGTTGGCCCCAGCACTGAGGTGATTGCCGGGGAAAACCTGATCCTGACAGCGG
GCGGGATCGATGCCCATGTGCATTTCATCTGTCCGCAGCTGTGCGAGTTTGCCATCGCCTCGGGAGTGACCACCCTTTTG
GGGGGCGGAACTGGGCCGGCCACAGGCAGCAACGCCACCACCTGCACCCCTGGAGCTTGGAACTTGGGCAAGATGTTGCA
GGCGGCGGAGGGGTTCCCCGTCAATTTGGGCTTTTTTGGCAAGGGAAACGCGGCTTTTCCCGCAGCTTTGCGGGAACAGG
TGGAAGCGGGGGCCTGCGGCCTCAAGATCCACGAAGATTGGGGATCCACGCCGGCGGTGATCGACAGCTGTTTGCAGGTC
GCGGATGAGTACGACATCCAAACCCTCATCCACACCGATACCTTAAATGAGTCCGCTTTCGTGGAGGACACTATCGCTGC
CATCAATGGCCGCACCATTCACACCTTCCACACCGAAGGGGCCGGGGGTGGGCATGCCCCCGATATCATTCGCATTGCCT
CTGAGCCCAACGTGCTGCCCAGCTCCACCAATCCCACCCGCCCCTTTACCCGCAACACCATCGAAGAGCATCTGGACATG
CTGATGGTGTGTCACCACCTGAGCAAGAATGTGCCGGAGGATATTGCTTTTGCCGAAAGCCGCATTCGTCCCCAAACCAT
CGCCGCCGAAGACATCTTGCATGACATGGGGGTGTTCAGCATCATCTCTTCCGACTCGCAGGCCATGGGCCGGGTGGGGG
AGGTGATCATCCGCACTTGGCAGACGGCTCACAAGATGAAGGTGCAGCGGGGGCCTTTGCCACAAGACAGCAGCCGCAAC
GACAACTTCCGGGCCAAGCGTTACGTAGCCAAGTACACCATCTGCCCTGCCATCGCCCAAGGACTCAGCCACGTCATCGG
GTCGGTGGAGGTGGGAAAGCTGGCGGATCTGTGTCTATGGAAGCCGGCCTTTTTTGGGGTTAAGCCGGAAATCGTCCTGA
AGGGGGGCCTGATTGCCTACGCCCAGATGGGGGATCCCAATGCTTCCATTCCGACCCCGCAGCCGGTGTACCCTCGCCCC
ATGTTCGGCAGCTTTGGCCGCGCCTTGACCGAGACCAGCCTCCTCTTTGTCTCCCAGGCTGCCCTAGACCTGGGGATCCC
GGAAAAACTGGGGATCCAGCGCCGGGCCGTAGCGGTGAAAAATTGCCGCGAGATCGGCAAAGCGGATTTGAAACTCAATA
CCGCCACTCCCCACATTGAGGTGAACCCGGAGACCTATGAAGTGCGGGCCGATGGAGAATTGCTCACCTGCGAGCCGGCA
GAGGTGCTGCCCATGGCGCAGCGGTATTTTCTGTTCTAA

Upstream 100 bases:

>100_bases
GGTTCTAATGAAGGGTTGAAACCAGACAACAAGCAGCAAGGGATCCCCTGGGTGGGGATGTGTGGTAAAACCCTGGCAGC
CCTTTTGCAGATACCACCCT

Downstream 100 bases:

>100_bases
TTTGGGTGTTCTAATTTGGGAGAGTTTGAGAGCTCTATTGAGCGTTTGATCGGTAACCCAAGCATGGGCCACCTTGTTCT
CCGCCACCTCAGCAAGCGCT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTLEIPRRQYVSNYGPTVGDRVRLADTELIIEVEEDFTTYGEEIKFGGGKTIRDGMGQSPTATRANGALDLVITNALILD
WWGIVKADVGIRDGYIVGIGKAGNPNIQAGVTPGMVVGPSTEVIAGENLILTAGGIDAHVHFICPQLCEFAIASGVTTLL
GGGTGPATGSNATTCTPGAWNLGKMLQAAEGFPVNLGFFGKGNAAFPAALREQVEAGACGLKIHEDWGSTPAVIDSCLQV
ADEYDIQTLIHTDTLNESAFVEDTIAAINGRTIHTFHTEGAGGGHAPDIIRIASEPNVLPSSTNPTRPFTRNTIEEHLDM
LMVCHHLSKNVPEDIAFAESRIRPQTIAAEDILHDMGVFSIISSDSQAMGRVGEVIIRTWQTAHKMKVQRGPLPQDSSRN
DNFRAKRYVAKYTICPAIAQGLSHVIGSVEVGKLADLCLWKPAFFGVKPEIVLKGGLIAYAQMGDPNASIPTPQPVYPRP
MFGSFGRALTETSLLFVSQAALDLGIPEKLGIQRRAVAVKNCREIGKADLKLNTATPHIEVNPETYEVRADGELLTCEPA
EVLPMAQRYFLF

Sequences:

>Translated_572_residues
MTLEIPRRQYVSNYGPTVGDRVRLADTELIIEVEEDFTTYGEEIKFGGGKTIRDGMGQSPTATRANGALDLVITNALILD
WWGIVKADVGIRDGYIVGIGKAGNPNIQAGVTPGMVVGPSTEVIAGENLILTAGGIDAHVHFICPQLCEFAIASGVTTLL
GGGTGPATGSNATTCTPGAWNLGKMLQAAEGFPVNLGFFGKGNAAFPAALREQVEAGACGLKIHEDWGSTPAVIDSCLQV
ADEYDIQTLIHTDTLNESAFVEDTIAAINGRTIHTFHTEGAGGGHAPDIIRIASEPNVLPSSTNPTRPFTRNTIEEHLDM
LMVCHHLSKNVPEDIAFAESRIRPQTIAAEDILHDMGVFSIISSDSQAMGRVGEVIIRTWQTAHKMKVQRGPLPQDSSRN
DNFRAKRYVAKYTICPAIAQGLSHVIGSVEVGKLADLCLWKPAFFGVKPEIVLKGGLIAYAQMGDPNASIPTPQPVYPRP
MFGSFGRALTETSLLFVSQAALDLGIPEKLGIQRRAVAVKNCREIGKADLKLNTATPHIEVNPETYEVRADGELLTCEPA
EVLPMAQRYFLF
>Mature_571_residues
TLEIPRRQYVSNYGPTVGDRVRLADTELIIEVEEDFTTYGEEIKFGGGKTIRDGMGQSPTATRANGALDLVITNALILDW
WGIVKADVGIRDGYIVGIGKAGNPNIQAGVTPGMVVGPSTEVIAGENLILTAGGIDAHVHFICPQLCEFAIASGVTTLLG
GGTGPATGSNATTCTPGAWNLGKMLQAAEGFPVNLGFFGKGNAAFPAALREQVEAGACGLKIHEDWGSTPAVIDSCLQVA
DEYDIQTLIHTDTLNESAFVEDTIAAINGRTIHTFHTEGAGGGHAPDIIRIASEPNVLPSSTNPTRPFTRNTIEEHLDML
MVCHHLSKNVPEDIAFAESRIRPQTIAAEDILHDMGVFSIISSDSQAMGRVGEVIIRTWQTAHKMKVQRGPLPQDSSRND
NFRAKRYVAKYTICPAIAQGLSHVIGSVEVGKLADLCLWKPAFFGVKPEIVLKGGLIAYAQMGDPNASIPTPQPVYPRPM
FGSFGRALTETSLLFVSQAALDLGIPEKLGIQRRAVAVKNCREIGKADLKLNTATPHIEVNPETYEVRADGELLTCEPAE
VLPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_SYNJB (Q2JQ88)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_476287.1
- ProteinModelPortal:   Q2JQ88
- SMR:   Q2JQ88
- STRING:   Q2JQ88
- GeneID:   3902138
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_0023
- TIGR:   CYB_0023
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   SSP321332:CYB_0023-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61377; Mature: 61246

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 325-325 BINDING 224-224

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEIPRRQYVSNYGPTVGDRVRLADTELIIEVEEDFTTYGEEIKFGGGKTIRDGMGQSP
CCCCCCHHHHHHHCCCCCCCEEEEECCEEEEEECHHHHCCCCEEEECCCCCHHCCCCCCC
TATRANGALDLVITNALILDWWGIVKADVGIRDGYIVGIGKAGNPNIQAGVTPGMVVGPS
CCCCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCEEECCCCCEEECCC
TEVIAGENLILTAGGIDAHVHFICPQLCEFAIASGVTTLLGGGTGPATGSNATTCTPGAW
CCEEECCCEEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCC
NLGKMLQAAEGFPVNLGFFGKGNAAFPAALREQVEAGACGLKIHEDWGSTPAVIDSCLQV
CHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHH
ADEYDIQTLIHTDTLNESAFVEDTIAAINGRTIHTFHTEGAGGGHAPDIIRIASEPNVLP
HHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCCCC
SSTNPTRPFTRNTIEEHLDMLMVCHHLSKNVPEDIAFAESRIRPQTIAAEDILHDMGVFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IISSDSQAMGRVGEVIIRTWQTAHKMKVQRGPLPQDSSRNDNFRAKRYVAKYTICPAIAQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GLSHVIGSVEVGKLADLCLWKPAFFGVKPEIVLKGGLIAYAQMGDPNASIPTPQPVYPRP
HHHHHHCCCCHHHHHHHHHCCHHHCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCC
MFGSFGRALTETSLLFVSQAALDLGIPEKLGIQRRAVAVKNCREIGKADLKLNTATPHIE
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCEEEECCCCEEE
VNPETYEVRADGELLTCEPAEVLPMAQRYFLF
ECCCEEEEEECCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
TLEIPRRQYVSNYGPTVGDRVRLADTELIIEVEEDFTTYGEEIKFGGGKTIRDGMGQSP
CCCCCHHHHHHHCCCCCCCEEEEECCEEEEEECHHHHCCCCEEEECCCCCHHCCCCCCC
TATRANGALDLVITNALILDWWGIVKADVGIRDGYIVGIGKAGNPNIQAGVTPGMVVGPS
CCCCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCEEECCCCCEEECCC
TEVIAGENLILTAGGIDAHVHFICPQLCEFAIASGVTTLLGGGTGPATGSNATTCTPGAW
CCEEECCCEEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCC
NLGKMLQAAEGFPVNLGFFGKGNAAFPAALREQVEAGACGLKIHEDWGSTPAVIDSCLQV
CHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHH
ADEYDIQTLIHTDTLNESAFVEDTIAAINGRTIHTFHTEGAGGGHAPDIIRIASEPNVLP
HHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCCCC
SSTNPTRPFTRNTIEEHLDMLMVCHHLSKNVPEDIAFAESRIRPQTIAAEDILHDMGVFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IISSDSQAMGRVGEVIIRTWQTAHKMKVQRGPLPQDSSRNDNFRAKRYVAKYTICPAIAQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GLSHVIGSVEVGKLADLCLWKPAFFGVKPEIVLKGGLIAYAQMGDPNASIPTPQPVYPRP
HHHHHHCCCCHHHHHHHHHCCHHHCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCC
MFGSFGRALTETSLLFVSQAALDLGIPEKLGIQRRAVAVKNCREIGKADLKLNTATPHIE
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCEEEECCCCEEE
VNPETYEVRADGELLTCEPAEVLPMAQRYFLF
ECCCEEEEEECCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA