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The map label for this gene is gap-3

Identifier: 86606819

GI number: 86606819

Start: 2195310

End: 2196320

Strand: Reverse

Name: gap-3

Synonym: CYA_2179

Alternate gene names: 86606819

Gene position: 2196320-2195310 (Counterclockwise)

Preceding gene: 86606820

Following gene: 86606818

Centisome position: 74.89

GC content: 61.03

Gene sequence:

>1011_bases
ATGGCGGCACGGGTGGGTATCAACGGTTTTGGCCGCATTGGGCGTTTGGTGCTGCGGGCGGCTTGGGGTTGGCCGGAGCT
GGAGTTTGCCCACATCAACGAGATCAAAGGTGGGCCTGCTACTGCGGCTCACCTGCTCAAGTTCGACTCAGTGCAGGGCC
GCTGGAACACCGACATCGAGGCATCTGAGCAACGGCTGCGCATCCAAGACAAAACCCTTACCTTCAGCGAGTTCAAATCT
CCCGGCGAAGTCCCTTGGGCGGATCTGGGGATCGACCTGGTGCTGGAGTGCTCGGGCAAATTCGTCAAGGCGGCAGAGCT
GGATGCCTACTTCAAAGCAGGGGTGCGCAAAGTCATTGTGGCTGCCCCCGTCCAGGATGAAGAGGCCCTCAACATCGTCA
TGGGCGTCAACGACCACCTCTACGACCCCGCTCGCCACCATTTGCTCACAGCCGCCTCCTGCACCACCAACTGCCTGGCC
CCCTTGGTAAAGGTCATCCACGAGGGGATCGGCATCCTGCACGGGGTGATCACCACCGTCCACGACGTCACCAATACCCA
AAGTATGGTGGATGCCCCCCACAAAGACCTGCGGCGGGCCCGCTCGGCTCTGCTGTCTTTGGTGCCCACCACCACCGGCT
CGGCCAAGGCCATCGGCCTCATCTACCCTGAGCTGAAGGGAAAGCTCAACGGCCTTGCCGTGCGCGTGCCCCTGCTCAAT
GCCTCTTTGACCGACGCGGTGTTCGAGGTAAAGCGGCCCACCACGGTGGAAGAGGTGAATCATCTCTTAAAAACGGCAGC
CGAGGGGGAACTCAAGGGCATCCTTGGCTATGAGGAGCTGCCGCTGGTCTCGGTGGATTTCAAGGGGGATCCCCGCTCCA
GCATTGTGGATGCCCCTTCCACCATGGTGGTAGATGGCACGCAGGTGAAGATCCTGGCCTGGTACGACAACGAATGGGGC
TACGCCAACCGCATGGCGGAATTGGCCCGCAAGGTGGCCCTCAGTTTATAG

Upstream 100 bases:

>100_bases
GTGCAAGGTTGCCCAGGGCCTGGCCGATTCTCCTTAACTTGATAACCCCGAGTTAGCTCTGGTAGGCTTTAGGTGAGATT
CGGCTGGGGGGAGGGGATCT

Downstream 100 bases:

>100_bases
AAGCGTTTTTTGAAGCATCCCCCTTGGAGGCCTGCCCATGACTGCTGTCTCGAGCGCCCAAGCTGCCGCCGTGCGCAACT
ATGCCCTGGTAACGGCTGCC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAARVGINGFGRIGRLVLRAAWGWPELEFAHINEIKGGPATAAHLLKFDSVQGRWNTDIEASEQRLRIQDKTLTFSEFKS
PGEVPWADLGIDLVLECSGKFVKAAELDAYFKAGVRKVIVAAPVQDEEALNIVMGVNDHLYDPARHHLLTAASCTTNCLA
PLVKVIHEGIGILHGVITTVHDVTNTQSMVDAPHKDLRRARSALLSLVPTTTGSAKAIGLIYPELKGKLNGLAVRVPLLN
ASLTDAVFEVKRPTTVEEVNHLLKTAAEGELKGILGYEELPLVSVDFKGDPRSSIVDAPSTMVVDGTQVKILAWYDNEWG
YANRMAELARKVALSL

Sequences:

>Translated_336_residues
MAARVGINGFGRIGRLVLRAAWGWPELEFAHINEIKGGPATAAHLLKFDSVQGRWNTDIEASEQRLRIQDKTLTFSEFKS
PGEVPWADLGIDLVLECSGKFVKAAELDAYFKAGVRKVIVAAPVQDEEALNIVMGVNDHLYDPARHHLLTAASCTTNCLA
PLVKVIHEGIGILHGVITTVHDVTNTQSMVDAPHKDLRRARSALLSLVPTTTGSAKAIGLIYPELKGKLNGLAVRVPLLN
ASLTDAVFEVKRPTTVEEVNHLLKTAAEGELKGILGYEELPLVSVDFKGDPRSSIVDAPSTMVVDGTQVKILAWYDNEWG
YANRMAELARKVALSL
>Mature_335_residues
AARVGINGFGRIGRLVLRAAWGWPELEFAHINEIKGGPATAAHLLKFDSVQGRWNTDIEASEQRLRIQDKTLTFSEFKSP
GEVPWADLGIDLVLECSGKFVKAAELDAYFKAGVRKVIVAAPVQDEEALNIVMGVNDHLYDPARHHLLTAASCTTNCLAP
LVKVIHEGIGILHGVITTVHDVTNTQSMVDAPHKDLRRARSALLSLVPTTTGSAKAIGLIYPELKGKLNGLAVRVPLLNA
SLTDAVFEVKRPTTVEEVNHLLKTAAEGELKGILGYEELPLVSVDFKGDPRSSIVDAPSTMVVDGTQVKILAWYDNEWGY
ANRMAELARKVALSL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=41.0876132930514, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=40.6727828746177, Blast_Score=262, Evalue=4e-70,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=41.0334346504559, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=41.0334346504559, Blast_Score=259, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=41.1242603550296, Blast_Score=263, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=41.3690476190476, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=41.3690476190476, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=40.8284023668639, Blast_Score=262, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=41.3897280966767, Blast_Score=275, Evalue=9e-75,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=42.4698795180723, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=40.4833836858006, Blast_Score=265, Evalue=8e-72,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=38.7692307692308, Blast_Score=260, Evalue=7e-70,
Organism=Drosophila melanogaster, GI85725000, Length=329, Percent_Identity=40.1215805471125, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI22023983, Length=329, Percent_Identity=40.1215805471125, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=39.8176291793313, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=39.8176291793313, Blast_Score=242, Evalue=3e-64,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36524; Mature: 36393

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARVGINGFGRIGRLVLRAAWGWPELEFAHINEIKGGPATAAHLLKFDSVQGRWNTDIE
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
ASEQRLRIQDKTLTFSEFKSPGEVPWADLGIDLVLECSGKFVKAAELDAYFKAGVRKVIV
CCHHHEEEECCEEEHHHCCCCCCCCHHHCCEEEEEECCCCEEEHHHHHHHHHHCHHEEEE
AAPVQDEEALNIVMGVNDHLYDPARHHLLTAASCTTNCLAPLVKVIHEGIGILHGVITTV
ECCCCCCCCEEEEECCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDVTNTQSMVDAPHKDLRRARSALLSLVPTTTGSAKAIGLIYPELKGKLNGLAVRVPLLN
HHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCCCEEEEEEEEC
ASLTDAVFEVKRPTTVEEVNHLLKTAAEGELKGILGYEELPLVSVDFKGDPRSSIVDAPS
CHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEECCCCCCCEEEEECCCCCCCCCCCCCC
TMVVDGTQVKILAWYDNEWGYANRMAELARKVALSL
EEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AARVGINGFGRIGRLVLRAAWGWPELEFAHINEIKGGPATAAHLLKFDSVQGRWNTDIE
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
ASEQRLRIQDKTLTFSEFKSPGEVPWADLGIDLVLECSGKFVKAAELDAYFKAGVRKVIV
CCHHHEEEECCEEEHHHCCCCCCCCHHHCCEEEEEECCCCEEEHHHHHHHHHHCHHEEEE
AAPVQDEEALNIVMGVNDHLYDPARHHLLTAASCTTNCLAPLVKVIHEGIGILHGVITTV
ECCCCCCCCEEEEECCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDVTNTQSMVDAPHKDLRRARSALLSLVPTTTGSAKAIGLIYPELKGKLNGLAVRVPLLN
HHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCCCEEEEEEEEC
ASLTDAVFEVKRPTTVEEVNHLLKTAAEGELKGILGYEELPLVSVDFKGDPRSSIVDAPS
CHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEECCCCCCCEEEEECCCCCCCCCCCCCC
TMVVDGTQVKILAWYDNEWGYANRMAELARKVALSL
EEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]