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The map label for this gene is thiL

Identifier: 86606546

GI number: 86606546

Start: 1909497

End: 1910519

Strand: Reverse

Name: thiL

Synonym: CYA_1899

Alternate gene names: 86606546

Gene position: 1910519-1909497 (Counterclockwise)

Preceding gene: 86606547

Following gene: 86606545

Centisome position: 65.14

GC content: 66.57

Gene sequence:

>1023_bases
TTGTTCAGCGATCTTCCCGACTTTTTCCCTCAACCCAAGAGCAGCTCTTCTCCCACGCCCATCTCGGCCATCGGCGAGGC
GGGGCTGTTGCAGATCGTGCAGCGCTACTGTCCTGCCCAGGTGGTGGGAGACGACGGGGCGGTGTTGCCCGCTCCTGAGG
GGCAGTTGGTGGTGAGCACCGATGTCTTGGTGGAGGGGGTTCACTTTAGCGACGTGACAACCCCGGCCCACGCGGTGGGC
TGGCGGGCGGTGGCGGCCAATCTCTCGGATCTGGCAGCGATGGGATCCCGTCCGCGGGCGTTGGTGGTGGGCTTGGGCCT
GCCGGGATCCACGCCGGTGGCTTGGGTAGAGGAGCTCTACGAAGGGATGCGGGCCTGCTGTGCCCGTTGGGGAGCAGAAT
TGGTGGGGGGGGATCTGTGTCGGTCGCCGCAGCGGTTTGTGGCGATCACGGCCCTGGGATCGGTGCAGCCGGGGCGGGCG
ATTGAGCGCAGACGGGCTCAGCCGGGCGATTGGCTGGTGGTCACAGGGCCCCACGGCGACGCGCGGGCCGGCCTGGAGCT
GCTGCTCCATCCCGAACAGGGATCCTCAGCCACGGCAGCACAGCGGCAGCAGTTGATCAGAGCCCACCAATACCCGCGCC
CGCGCTTGGATGTTCTGTCCCTTTTGGAAGCGCTCCCCGGTCCTCTGCGCCTGGCCGGCATGGACACCAGCGATGGCTTG
GCGGACGCCCTGGTGCAGGTGTGCCAGAGCAGTGGGGTAGCGGCGCGGATCGCGGCGGAGCGGATCCCGATTTCGGTGGC
TTTGCGCCAGGCGTTCCCGGCCCAAGCTTTGGAGTGGGCGCTTTATGGGGGCGAAGACTTTGAGCTGCTTCTCAGTGCCG
AGGTGTCGGTGGCCAAGCATCTGTTGGAAAAGTTGCCAGGAGCCGCCTGGATTGGGGAAGTAACCGGCTGGGATCCGCAG
GGGACGGTGCGGTTGCAGGACGGGCAAATCCTCAGCCGCCAGCAGGCCTTCCAGCACTTTTGA

Upstream 100 bases:

>100_bases
AATCTTTGGACGAGTAGGGGCTTGGGCTTGACCGGCGCCAACTGCCCCTAACATTTTGCAACCATAGGTTTTTGGCTGCG
TGCATCCGCCAGGGGCTCCT

Downstream 100 bases:

>100_bases
GCCTGTCTGAAAAACTCACTGGCCACCTAGGCCGCTCAAAACTGCCCAAAGTTGAAAACCAAGCTACTCGAGTCGGAAAG
GAAACCGGAACTGGGATTGG

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MFSDLPDFFPQPKSSSSPTPISAIGEAGLLQIVQRYCPAQVVGDDGAVLPAPEGQLVVSTDVLVEGVHFSDVTTPAHAVG
WRAVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQRFVAITALGSVQPGRA
IERRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRLDVLSLLEALPGPLRLAGMDTSDGL
ADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEWALYGGEDFELLLSAEVSVAKHLLEKLPGAAWIGEVTGWDPQ
GTVRLQDGQILSRQQAFQHF

Sequences:

>Translated_340_residues
MFSDLPDFFPQPKSSSSPTPISAIGEAGLLQIVQRYCPAQVVGDDGAVLPAPEGQLVVSTDVLVEGVHFSDVTTPAHAVG
WRAVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQRFVAITALGSVQPGRA
IERRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRLDVLSLLEALPGPLRLAGMDTSDGL
ADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEWALYGGEDFELLLSAEVSVAKHLLEKLPGAAWIGEVTGWDPQ
GTVRLQDGQILSRQQAFQHF
>Mature_340_residues
MFSDLPDFFPQPKSSSSPTPISAIGEAGLLQIVQRYCPAQVVGDDGAVLPAPEGQLVVSTDVLVEGVHFSDVTTPAHAVG
WRAVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQRFVAITALGSVQPGRA
IERRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRLDVLSLLEALPGPLRLAGMDTSDGL
ADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEWALYGGEDFELLLSAEVSVAKHLLEKLPGAAWIGEVTGWDPQ
GTVRLQDGQILSRQQAFQHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=307, Percent_Identity=37.1335504885993, Blast_Score=150, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36101; Mature: 36101

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDLPDFFPQPKSSSSPTPISAIGEAGLLQIVQRYCPAQVVGDDGAVLPAPEGQLVVST
CCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCEEECCCCCEEECCCCCEEEEH
DVLVEGVHFSDVTTPAHAVGWRAVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELY
HHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
EGMRACCARWGAELVGGDLCRSPQRFVAITALGSVQPGRAIERRRAQPGDWLVVTGPHGD
HHHHHHHHHHCHHHHCCHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCEEEEECCCCC
ARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRLDVLSLLEALPGPLRLAGMDTSDGL
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCH
ADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEWALYGGEDFELLLSAEVSVAKH
HHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHCCHHHHHEEEECCCCEEEEEEHHHHHHHH
LLEKLPGAAWIGEVTGWDPQGTVRLQDGQILSRQQAFQHF
HHHHCCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MFSDLPDFFPQPKSSSSPTPISAIGEAGLLQIVQRYCPAQVVGDDGAVLPAPEGQLVVST
CCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCEEECCCCCEEECCCCCEEEEH
DVLVEGVHFSDVTTPAHAVGWRAVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELY
HHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
EGMRACCARWGAELVGGDLCRSPQRFVAITALGSVQPGRAIERRRAQPGDWLVVTGPHGD
HHHHHHHHHHCHHHHCCHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCEEEEECCCCC
ARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRLDVLSLLEALPGPLRLAGMDTSDGL
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCH
ADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEWALYGGEDFELLLSAEVSVAKH
HHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHCCHHHHHEEEECCCCEEEEEEHHHHHHHH
LLEKLPGAAWIGEVTGWDPQGTVRLQDGQILSRQQAFQHF
HHHHCCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA