Click here to switch to the map view.

The map label for this gene is crtH

Identifier: 86606507

GI number: 86606507

Start: 1861251

End: 1862810

Strand: Reverse

Name: crtH

Synonym: CYA_1857

Alternate gene names: 86606507

Gene position: 1862810-1861251 (Counterclockwise)

Preceding gene: 86606508

Following gene: 86606506

Centisome position: 63.52

GC content: 64.04

Gene sequence:

>1560_bases
TTGACCCAAACGCTGTTTTCTCGACCTCAAGCTACGGCACCTCCTGCTTCCCCCCCTTCTGTTTGGGATGTCATTGTCAT
TGGCGCTGGGATTGGCGGCCTGGTGGCGGCCACCCAGTTGGCGGCCAAGGGCTACCGGGTGTTGGTGCTGGAAAAATACC
TCATCCCTGGTGGCAGCGCCGGCTACTTTGAGCGCCCGGATCCCAACGGCAACGGGATCTACCGCTTCGACGTCGGGGCT
TCCATGATCTTTGGCCTGGGCAGGCAGGGCACCACCAACCTGCTTACCCGCGCCTTGGCTGCCGTGGGCCAGTCTTTGGA
CTCCATCCCCGACCCGGTGCAGATTGCCTACCACCTGCCCCAGGGGCTCAGCCCGCGCGTACACCGGAACTACGAGGAGT
TTTTGCAGGAGCTAGCTAGCTATTTCCCTCAGGAAGCGGGCGGCATCCGCCGTTTCTACGACAGCTTCTGGCCTATCTTC
AACAGCCTCAACGCCATGGAGCTGCTCTCTTTGGAGGAGTGGGGCTATCTCTGGCGCTCTTTTGTCGGCAACCCCCGCGC
CTGCCTGACTTTGGCCCGCTATTTGCCGGCCAATGTGGGCCAGGTGGCGCGGCGCCACCTCCGCCATCCGGCGCTGCTGC
GCTTTGTGGATATGGAGTGCTACTGCTGGTCGGTGGTGCCGGCGGAGCGCACGCCCATGATCAACGCCGGCATGGTGTTC
TGCGACCGCCACTACGGTGGCGTCAACTACCCCAAGGGAGGGGTGGGGCAGATTGCTCAAAAGCTGGCCCAGGGGCTAGA
GACCTGCGGGGGGCAAATCCGCTACCGAGCGTCGGTGCGGCGGATTTTGGCAGAACGGGGCCGGGCCGTGGGCGTCGAGC
TCTCCACGGGGGAAAAGCTCTTTGCGCGCAAGATCATCTCCAATGCCACCCGCTGGGATACCTTTGGCCGCCTCTGGCCA
GGACCCTTTCCGGCAGCGGAGCGGCGCTGGCAAAGCCGTTATCAACAGTCCCCCAGTTTCTTAAGCCTGCACTTGGGGGT
GCGGGCCGAGCCTCTGGCCGGCGAGCGCTACTGCCACCACATTCTTCTAGAAGATTGGCAAGACCTGGAGGCGGAGCAGG
GCACGATCTTCGTCTCCATCCCCACCCTTTTGGATCCGGAGCTGGCCCCACCAGGCCGCCACATTGTCCACGCCTTTACC
CCCAGTTGGATGCAGACTTGGCAGGGCTTGAGCCCAGAGCAGTACCGGCAGCAAAAACAAGCGGCAGCCGAGCGTCTCAT
CCGCCGCCTGGAGGCCCTCTGGCCTGGTCTGGGATCCCACATTGAACTGCAGGAAGTGGGCACCCCCCGCACCCACCGCC
GCTTCTTGGGCCGCGTCGACGGCACCTACGGCCCCATCCCTCGCGGCACTCCCTGGGGACTCTTGGGCATGCCCTTCAAC
CGCACCGCCATCCCCAACCTCTACTGCGTGGGGGATAGCACCTTCCCCGGCCAGGGACTCAACGCTGTCGCTTTCTCTGG
GTTTGCCTGCGCCCACCGGGTAGCGGCGGACTTCTCCTAA

Upstream 100 bases:

>100_bases
AGATCTGATCTAAGTCGCTGCAAACGGCTGGGATTGGATGGCGGATGCTGCCTGAAGCTTTGGTAGGTTGAGGATACTGG
CGTTGCGCTAGAGGGATCCC

Downstream 100 bases:

>100_bases
AGCTGTCTCCAATTTCTAGGAACCCCCCGCAGTCGTCTTGCATTGAACCCCTTCCCACTGCGAGAGCTCTTGCATGAGCG
TCGGGGTGAGGCATCGAAGC

Product: carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MTQTLFSRPQATAPPASPPSVWDVIVIGAGIGGLVAATQLAAKGYRVLVLEKYLIPGGSAGYFERPDPNGNGIYRFDVGA
SMIFGLGRQGTTNLLTRALAAVGQSLDSIPDPVQIAYHLPQGLSPRVHRNYEEFLQELASYFPQEAGGIRRFYDSFWPIF
NSLNAMELLSLEEWGYLWRSFVGNPRACLTLARYLPANVGQVARRHLRHPALLRFVDMECYCWSVVPAERTPMINAGMVF
CDRHYGGVNYPKGGVGQIAQKLAQGLETCGGQIRYRASVRRILAERGRAVGVELSTGEKLFARKIISNATRWDTFGRLWP
GPFPAAERRWQSRYQQSPSFLSLHLGVRAEPLAGERYCHHILLEDWQDLEAEQGTIFVSIPTLLDPELAPPGRHIVHAFT
PSWMQTWQGLSPEQYRQQKQAAAERLIRRLEALWPGLGSHIELQEVGTPRTHRRFLGRVDGTYGPIPRGTPWGLLGMPFN
RTAIPNLYCVGDSTFPGQGLNAVAFSGFACAHRVAADFS

Sequences:

>Translated_519_residues
MTQTLFSRPQATAPPASPPSVWDVIVIGAGIGGLVAATQLAAKGYRVLVLEKYLIPGGSAGYFERPDPNGNGIYRFDVGA
SMIFGLGRQGTTNLLTRALAAVGQSLDSIPDPVQIAYHLPQGLSPRVHRNYEEFLQELASYFPQEAGGIRRFYDSFWPIF
NSLNAMELLSLEEWGYLWRSFVGNPRACLTLARYLPANVGQVARRHLRHPALLRFVDMECYCWSVVPAERTPMINAGMVF
CDRHYGGVNYPKGGVGQIAQKLAQGLETCGGQIRYRASVRRILAERGRAVGVELSTGEKLFARKIISNATRWDTFGRLWP
GPFPAAERRWQSRYQQSPSFLSLHLGVRAEPLAGERYCHHILLEDWQDLEAEQGTIFVSIPTLLDPELAPPGRHIVHAFT
PSWMQTWQGLSPEQYRQQKQAAAERLIRRLEALWPGLGSHIELQEVGTPRTHRRFLGRVDGTYGPIPRGTPWGLLGMPFN
RTAIPNLYCVGDSTFPGQGLNAVAFSGFACAHRVAADFS
>Mature_518_residues
TQTLFSRPQATAPPASPPSVWDVIVIGAGIGGLVAATQLAAKGYRVLVLEKYLIPGGSAGYFERPDPNGNGIYRFDVGAS
MIFGLGRQGTTNLLTRALAAVGQSLDSIPDPVQIAYHLPQGLSPRVHRNYEEFLQELASYFPQEAGGIRRFYDSFWPIFN
SLNAMELLSLEEWGYLWRSFVGNPRACLTLARYLPANVGQVARRHLRHPALLRFVDMECYCWSVVPAERTPMINAGMVFC
DRHYGGVNYPKGGVGQIAQKLAQGLETCGGQIRYRASVRRILAERGRAVGVELSTGEKLFARKIISNATRWDTFGRLWPG
PFPAAERRWQSRYQQSPSFLSLHLGVRAEPLAGERYCHHILLEDWQDLEAEQGTIFVSIPTLLDPELAPPGRHIVHAFTP
SWMQTWQGLSPEQYRQQKQAAAERLIRRLEALWPGLGSHIELQEVGTPRTHRRFLGRVDGTYGPIPRGTPWGLLGMPFNR
TAIPNLYCVGDSTFPGQGLNAVAFSGFACAHRVAADFS

Specific function: This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=556, Percent_Identity=23.5611510791367, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 57670; Mature: 57538

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTLFSRPQATAPPASPPSVWDVIVIGAGIGGLVAATQLAAKGYRVLVLEKYLIPGGSA
CCCCHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEEEEEECCCCCC
GYFERPDPNGNGIYRFDVGASMIFGLGRQGTTNLLTRALAAVGQSLDSIPDPVQIAYHLP
CCCCCCCCCCCCEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
QGLSPRVHRNYEEFLQELASYFPQEAGGIRRFYDSFWPIFNSLNAMELLSLEEWGYLWRS
CCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FVGNPRACLTLARYLPANVGQVARRHLRHPALLRFVDMECYCWSVVPAERTPMINAGMVF
HCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCEEE
CDRHYGGVNYPKGGVGQIAQKLAQGLETCGGQIRYRASVRRILAERGRAVGVELSTGEKL
EECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCEEEEEECCCHHH
FARKIISNATRWDTFGRLWPGPFPAAERRWQSRYQQSPSFLSLHLGVRAEPLAGERYCHH
HHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHH
ILLEDWQDLEAEQGTIFVSIPTLLDPELAPPGRHIVHAFTPSWMQTWQGLSPEQYRQQKQ
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHCCCCHHHHHHHHH
AAAERLIRRLEALWPGLGSHIELQEVGTPRTHRRFLGRVDGTYGPIPRGTPWGLLGMPFN
HHHHHHHHHHHHHCCCCCCCEEHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCC
RTAIPNLYCVGDSTFPGQGLNAVAFSGFACAHRVAADFS
CCCCCEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
TQTLFSRPQATAPPASPPSVWDVIVIGAGIGGLVAATQLAAKGYRVLVLEKYLIPGGSA
CCCHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEEEEEECCCCCC
GYFERPDPNGNGIYRFDVGASMIFGLGRQGTTNLLTRALAAVGQSLDSIPDPVQIAYHLP
CCCCCCCCCCCCEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
QGLSPRVHRNYEEFLQELASYFPQEAGGIRRFYDSFWPIFNSLNAMELLSLEEWGYLWRS
CCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FVGNPRACLTLARYLPANVGQVARRHLRHPALLRFVDMECYCWSVVPAERTPMINAGMVF
HCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCEEE
CDRHYGGVNYPKGGVGQIAQKLAQGLETCGGQIRYRASVRRILAERGRAVGVELSTGEKL
EECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCEEEEEECCCHHH
FARKIISNATRWDTFGRLWPGPFPAAERRWQSRYQQSPSFLSLHLGVRAEPLAGERYCHH
HHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHH
ILLEDWQDLEAEQGTIFVSIPTLLDPELAPPGRHIVHAFTPSWMQTWQGLSPEQYRQQKQ
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHCCCCHHHHHHHHH
AAAERLIRRLEALWPGLGSHIELQEVGTPRTHRRFLGRVDGTYGPIPRGTPWGLLGMPFN
HHHHHHHHHHHHHCCCCCCCEEHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCC
RTAIPNLYCVGDSTFPGQGLNAVAFSGFACAHRVAADFS
CCCCCEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021167; 7721699; 10648776 [H]