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The map label for this gene is gltA [H]

Identifier: 86606394

GI number: 86606394

Start: 1743572

End: 1744708

Strand: Reverse

Name: gltA [H]

Synonym: CYA_1739

Alternate gene names: 86606394

Gene position: 1744708-1743572 (Counterclockwise)

Preceding gene: 86606395

Following gene: 86606393

Centisome position: 59.49

GC content: 60.07

Gene sequence:

>1137_bases
ATGGCGGATGGCGAATACAGGCCGGGGCTAGAAGGCGTTCCGGCCACGCGCTCTAACATTAGTTTTGTCGATGGCCAGGC
AGGGATCCTGGAGTATCGGGGCATTCCCATCGAGGAACTGACGGCCCAGAGCACCTTTCTGGAGACGGCCTATCTGCTGA
TCTTCGGCAAGCTGCCGACGCAAGCCGAGCTGGACAACTTCGATCAGGCCGTCCGCAGCCATCGGCGGGTGAAATACCGC
ATCCGCGACATGATCAAGTCGTTTCCCGAGTCGGGCCACCCCATGGATGCCCTGCAAACCTGTGTTGCCAGTCTGGGGAT
GTTCTATCCGGTGCGAGAGGCGGATCCCGACTATGTGTTCGGCACCGTCACCCGGTTGCTCTCCAAGCTGCCGACGATGG
TGGCGATGTTTCACCAGATGCGCCAGGGCAACGATCCCATCCCCCCCGACGACAGCCTGGATCATGCCGCCAATTTCCTC
TACATGCTCTCCGGCAAGAAGCCGGATCCCTGGCTGGCCCGCATCTTCGATACCTGCCTGATCTTGCACGCCGAACACAC
AGTCAATGCCTCTACTTTTGCCCTGCTGGTGAGCGCCTCTACCCTGGCCAGCCCCTATAGCAGCCTGGCCACGGCGGTGG
GTACCCTTTCGGGGCTGTTGCACGGCGGGGCCAACCAACAGGTGATGAGGCTGTTGCGACAAATCGGCTCGGTGGAAAAT
GTGCGCTCGTTTATCGAAGAGAAGCTGGCCAAAAAAGAGCGCATCATGGGCATGGGCCATCGCGTTTACAAGGTGAAGGA
TCCGCGGGCCACCATCCTGCAGCGGCTGGCAGAGGAGCTGTTCGAGCGCTACGGCCACGACAAGTACTACGACATTGCCC
TGGAGGTGGAGCGGGTGTGTGAGGAGTTGCTGGGGCCGAAGGGGATCTACCCGAATGTGGACTTCTACTCAGGGTTGGTC
TACGCCAAGCTGGGGATCCCAGAAGATTTGTTTACACCGGTGTTTGCCATTGCCCGAGCGGCGGGTTGGCTGGCCCATTG
GCGGGAGCAGTTGTCCGATAATCGGCTTTTCCGACCCACCCAGGTGTACACAGGCGAACGCCAGCAACGCTACATCCCTA
TAGAAGAGCGGGGTTGA

Upstream 100 bases:

>100_bases
AAGGCGGGATCTGGCTTCAGAGATCCAGATCTGCTTTAATGTAGCGAATGTAGTGACGCCCCTGTTCTCTCCTTGGGGGG
CTCATTTCAGGGATCCGACT

Downstream 100 bases:

>100_bases
GAGCCGTTTGACAGGGCGCTGGGCCGGGATCCCAACTCAATAGAGCCCAAATTGGTGTGAGGTGGTGCGTTGAGCCTTTT
GGATTCTCCTCTCTGGCGCG

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MADGEYRPGLEGVPATRSNISFVDGQAGILEYRGIPIEELTAQSTFLETAYLLIFGKLPTQAELDNFDQAVRSHRRVKYR
IRDMIKSFPESGHPMDALQTCVASLGMFYPVREADPDYVFGTVTRLLSKLPTMVAMFHQMRQGNDPIPPDDSLDHAANFL
YMLSGKKPDPWLARIFDTCLILHAEHTVNASTFALLVSASTLASPYSSLATAVGTLSGLLHGGANQQVMRLLRQIGSVEN
VRSFIEEKLAKKERIMGMGHRVYKVKDPRATILQRLAEELFERYGHDKYYDIALEVERVCEELLGPKGIYPNVDFYSGLV
YAKLGIPEDLFTPVFAIARAAGWLAHWREQLSDNRLFRPTQVYTGERQQRYIPIEERG

Sequences:

>Translated_378_residues
MADGEYRPGLEGVPATRSNISFVDGQAGILEYRGIPIEELTAQSTFLETAYLLIFGKLPTQAELDNFDQAVRSHRRVKYR
IRDMIKSFPESGHPMDALQTCVASLGMFYPVREADPDYVFGTVTRLLSKLPTMVAMFHQMRQGNDPIPPDDSLDHAANFL
YMLSGKKPDPWLARIFDTCLILHAEHTVNASTFALLVSASTLASPYSSLATAVGTLSGLLHGGANQQVMRLLRQIGSVEN
VRSFIEEKLAKKERIMGMGHRVYKVKDPRATILQRLAEELFERYGHDKYYDIALEVERVCEELLGPKGIYPNVDFYSGLV
YAKLGIPEDLFTPVFAIARAAGWLAHWREQLSDNRLFRPTQVYTGERQQRYIPIEERG
>Mature_377_residues
ADGEYRPGLEGVPATRSNISFVDGQAGILEYRGIPIEELTAQSTFLETAYLLIFGKLPTQAELDNFDQAVRSHRRVKYRI
RDMIKSFPESGHPMDALQTCVASLGMFYPVREADPDYVFGTVTRLLSKLPTMVAMFHQMRQGNDPIPPDDSLDHAANFLY
MLSGKKPDPWLARIFDTCLILHAEHTVNASTFALLVSASTLASPYSSLATAVGTLSGLLHGGANQQVMRLLRQIGSVENV
RSFIEEKLAKKERIMGMGHRVYKVKDPRATILQRLAEELFERYGHDKYYDIALEVERVCEELLGPKGIYPNVDFYSGLVY
AKLGIPEDLFTPVFAIARAAGWLAHWREQLSDNRLFRPTQVYTGERQQRYIPIEERG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=384, Percent_Identity=26.5625, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1786939, Length=379, Percent_Identity=36.6754617414248, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1786527, Length=373, Percent_Identity=33.2439678284182, Blast_Score=227, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17555174, Length=322, Percent_Identity=27.0186335403727, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319850, Length=369, Percent_Identity=27.9132791327913, Blast_Score=112, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324328, Length=367, Percent_Identity=26.4305177111717, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6325257, Length=377, Percent_Identity=24.6684350132626, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24640126, Length=371, Percent_Identity=27.7628032345013, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24640124, Length=371, Percent_Identity=27.7628032345013, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356863, Length=384, Percent_Identity=27.8645833333333, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 42636; Mature: 42505

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGEYRPGLEGVPATRSNISFVDGQAGILEYRGIPIEELTAQSTFLETAYLLIFGKLPT
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
QAELDNFDQAVRSHRRVKYRIRDMIKSFPESGHPMDALQTCVASLGMFYPVREADPDYVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
GTVTRLLSKLPTMVAMFHQMRQGNDPIPPDDSLDHAANFLYMLSGKKPDPWLARIFDTCL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHH
ILHAEHTVNASTFALLVSASTLASPYSSLATAVGTLSGLLHGGANQQVMRLLRQIGSVEN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHH
VRSFIEEKLAKKERIMGMGHRVYKVKDPRATILQRLAEELFERYGHDKYYDIALEVERVC
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
EELLGPKGIYPNVDFYSGLVYAKLGIPEDLFTPVFAIARAAGWLAHWREQLSDNRLFRPT
HHHCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QVYTGERQQRYIPIEERG
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADGEYRPGLEGVPATRSNISFVDGQAGILEYRGIPIEELTAQSTFLETAYLLIFGKLPT
CCCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
QAELDNFDQAVRSHRRVKYRIRDMIKSFPESGHPMDALQTCVASLGMFYPVREADPDYVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
GTVTRLLSKLPTMVAMFHQMRQGNDPIPPDDSLDHAANFLYMLSGKKPDPWLARIFDTCL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHH
ILHAEHTVNASTFALLVSASTLASPYSSLATAVGTLSGLLHGGANQQVMRLLRQIGSVEN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHH
VRSFIEEKLAKKERIMGMGHRVYKVKDPRATILQRLAEELFERYGHDKYYDIALEVERVC
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
EELLGPKGIYPNVDFYSGLVYAKLGIPEDLFTPVFAIARAAGWLAHWREQLSDNRLFRPT
HHHCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QVYTGERQQRYIPIEERG
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]