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The map label for this gene is pheA [H]

Identifier: 86606128

GI number: 86606128

Start: 1465840

End: 1466739

Strand: Reverse

Name: pheA [H]

Synonym: CYA_1460

Alternate gene names: 86606128

Gene position: 1466739-1465840 (Counterclockwise)

Preceding gene: 86606129

Following gene: 86606122

Centisome position: 50.01

GC content: 62.33

Gene sequence:

>900_bases
ATGGCTTTAATCGTCTCCTCTGCGCCGGTAGCCTTCCTCGGCCCTGTTGGAACCTACACGGAGTTGGCCGCTCTGCTCGC
CTGTCCCGAGCAGCCCCATCTCCATAGCCAGGGGTCCCATCCTCTGGTGCCCTACCCCACCATTAGCGCCTGCTTGGCAG
CCGTGGCTGCGGGCGAGCAAGAATGGGCGGTGGTGCCGGTGGAGAACTCCGTTGAGGGCGGGGTCTCGATGACCTTGGAT
GCCCTCTGGCAACTGGAGGGGCTGAGCATTCGCCAGGCGCTGATCCTGCCCATCCGCCATGCCCTCATCGGCTGCGCCTC
CCGGCTGGAGCAGATCGAGCAGGTCTATTCCCATCCGCAAGCCTTGGCCCAATGTCAGGCTTGGCTGGGATCCCATCTGC
CCCGGGCGACCTTGATTCCAACCCGCTCCACCACCGAAGAATTGGAGCGGCTGCGAGCACAGCCCAACGCTGCCGTCATT
GCTTCAGAGCGGGCCGCTGAGCTCTACCAACTGCCGGTTTTGGCCTGTCCCATCAACGACCACCCGGATAACTGCACCCG
CTTTTGGGTGGTGGGCCGTCGCCGTTCCTCGCCAGGGGGATCCCATACTTCCTTGGCCTTCAGCCTGCCCCACAATGTGC
CAGGGGCGCTGCTAAAGCCGCTGCAAGTCTTTGCAGAGCGGGGCCTCAATATGTCGCGCATTGAGTCGCGCCCCACCAAG
AAATCGGCGGGGACCTATGTCTTTTTTGTCGATCTGGAGAATCCGGTCGGCCAACCCTATCTGGATGCAGAGGTAATCGC
TGCCCTGGAAGCGATCGCAGAAACCCTGAAGCTTTTCGGCAGCTACCCCGTCCACGACCTCAGCAAGCCGAGCGAGCGTC
GTCCTTGCAACTCAGAATAG

Upstream 100 bases:

>100_bases
AAATCCCCGTTGCCCAGAGCCTGATTGCCCGCTGCAGCGCAACGTCGAGGCAGTAGAGTTAGAGCTGGCTCCTAGCGACA
CTCGCAAACAAAACTAAAGA

Downstream 100 bases:

>100_bases
GACAGGCCGGCCAGGCCCGACTTGCTATCTGCGGGGATCCCGAAGCCTTTCCCTCCCCTCCTAGACCCAGATACGCTAAA
AGAATAGGGGAGGGTGAGGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MALIVSSAPVAFLGPVGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLAAVAAGEQEWAVVPVENSVEGGVSMTLD
ALWQLEGLSIRQALILPIRHALIGCASRLEQIEQVYSHPQALAQCQAWLGSHLPRATLIPTRSTTEELERLRAQPNAAVI
ASERAAELYQLPVLACPINDHPDNCTRFWVVGRRRSSPGGSHTSLAFSLPHNVPGALLKPLQVFAERGLNMSRIESRPTK
KSAGTYVFFVDLENPVGQPYLDAEVIAALEAIAETLKLFGSYPVHDLSKPSERRPCNSE

Sequences:

>Translated_299_residues
MALIVSSAPVAFLGPVGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLAAVAAGEQEWAVVPVENSVEGGVSMTLD
ALWQLEGLSIRQALILPIRHALIGCASRLEQIEQVYSHPQALAQCQAWLGSHLPRATLIPTRSTTEELERLRAQPNAAVI
ASERAAELYQLPVLACPINDHPDNCTRFWVVGRRRSSPGGSHTSLAFSLPHNVPGALLKPLQVFAERGLNMSRIESRPTK
KSAGTYVFFVDLENPVGQPYLDAEVIAALEAIAETLKLFGSYPVHDLSKPSERRPCNSE
>Mature_298_residues
ALIVSSAPVAFLGPVGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLAAVAAGEQEWAVVPVENSVEGGVSMTLDA
LWQLEGLSIRQALILPIRHALIGCASRLEQIEQVYSHPQALAQCQAWLGSHLPRATLIPTRSTTEELERLRAQPNAAVIA
SERAAELYQLPVLACPINDHPDNCTRFWVVGRRRSSPGGSHTSLAFSLPHNVPGALLKPLQVFAERGLNMSRIESRPTKK
SAGTYVFFVDLENPVGQPYLDAEVIAALEAIAETLKLFGSYPVHDLSKPSERRPCNSE

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=286, Percent_Identity=31.4685314685315, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324013, Length=330, Percent_Identity=27.8787878787879, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 32340; Mature: 32209

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIVSSAPVAFLGPVGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLAAVAAGEQ
CEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
EWAVVPVENSVEGGVSMTLDALWQLEGLSIRQALILPIRHALIGCASRLEQIEQVYSHPQ
CEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ALAQCQAWLGSHLPRATLIPTRSTTEELERLRAQPNAAVIASERAAELYQLPVLACPIND
HHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHCCEEEECCCC
HPDNCTRFWVVGRRRSSPGGSHTSLAFSLPHNVPGALLKPLQVFAERGLNMSRIESRPTK
CCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCC
KSAGTYVFFVDLENPVGQPYLDAEVIAALEAIAETLKLFGSYPVHDLSKPSERRPCNSE
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALIVSSAPVAFLGPVGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLAAVAAGEQ
EEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
EWAVVPVENSVEGGVSMTLDALWQLEGLSIRQALILPIRHALIGCASRLEQIEQVYSHPQ
CEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ALAQCQAWLGSHLPRATLIPTRSTTEELERLRAQPNAAVIASERAAELYQLPVLACPIND
HHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHCCEEEECCCC
HPDNCTRFWVVGRRRSSPGGSHTSLAFSLPHNVPGALLKPLQVFAERGLNMSRIESRPTK
CCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCC
KSAGTYVFFVDLENPVGQPYLDAEVIAALEAIAETLKLFGSYPVHDLSKPSERRPCNSE
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]