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The map label for this gene is yycF [H]

Identifier: 86606063

GI number: 86606063

Start: 1398863

End: 1399594

Strand: Reverse

Name: yycF [H]

Synonym: CYA_1392

Alternate gene names: 86606063

Gene position: 1399594-1398863 (Counterclockwise)

Preceding gene: 86606064

Following gene: 86606060

Centisome position: 47.72

GC content: 60.79

Gene sequence:

>732_bases
GTGGAAGCCCAGCGCAAAGAACGGATTCTCGTGGTCGATGATGAGGCCAGCATCCGCCGCATTTTGGAGACCCGCCTCTC
GATGATCGGGTACGACGTGGTTACTGCTGCCGACGGAGAGGAGGCGCTGGAGGTTTTTCGCAAGCAGGATCCTGACCTGG
TGGTGCTGGATGTGATGATGCCGAAGCTGGATGGCTACGGGGTCTGCCAGGAGTTGCGCAAAGAATCCGACATCCCGATC
ATCATGCTCACGGCGTTGGGGGACGTGGCCGACCGCATTACTGGCTTGGAACTGGGGGCAGACGACTACGTGGTTAAGCC
GTTTTCGCCCAAAGAACTGGAGGCCCGCATTCGTTCGGTGCTGAGGCGGGTGGCGCGGTCGTCCCATGAAGGGATCCCCA
GCTCAGGGGTAATTCAGGTGGGGGATCTTCGCATCGATACCAACAAGCGGCAGGTTTACAAGCGGGACGAGCGCATCCGC
CTGACGGGGATGGAGTTTAGTTTGCTGGAGCTGCTGGTCAGCCGGTCGGGGGAGCCGTTTTCCCGCGCCGAGATTTTGCA
AGAGGTGTGGGGCTACACGCCGGAGCGCCACGTGGATACGCGGGTGGTGGATGTCCACATCTCGCGGCTGCGGGCCAAGT
TGGAGGATGACCCGAGCAACCCTGAGCTTATCCTGACAGCCCGCGGTACCGGCTATCTGTTTCAGCGCATCGTTCCAAAA
GGCGAGGAGTAG

Upstream 100 bases:

>100_bases
GGAGGAGCCCCTGAGGAGGCTGCATCTGACCACCTCGAGTTCGCGCTCACCTCAATTTTTTCCAATCCTTTTCATTTAGA
AGTTTAGGAGTTGCAGCACC

Downstream 100 bases:

>100_bases
GACGGGATCCCCCTTAGTAGCTCTTCCAGGGCTGCCCGCACCTGTTGCAGCACACCAACCCAGTTGCCGCGGGCTTCTTG
GCGGAATAGGCGCATCACCC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTAADGEEALEVFRKQDPDLVVLDVMMPKLDGYGVCQELRKESDIPI
IMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVARSSHEGIPSSGVIQVGDLRIDTNKRQVYKRDERIR
LTGMEFSLLELLVSRSGEPFSRAEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVPK
GEE

Sequences:

>Translated_243_residues
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTAADGEEALEVFRKQDPDLVVLDVMMPKLDGYGVCQELRKESDIPI
IMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVARSSHEGIPSSGVIQVGDLRIDTNKRQVYKRDERIR
LTGMEFSLLELLVSRSGEPFSRAEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVPK
GEE
>Mature_243_residues
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTAADGEEALEVFRKQDPDLVVLDVMMPKLDGYGVCQELRKESDIPI
IMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVARSSHEGIPSSGVIQVGDLRIDTNKRQVYKRDERIR
LTGMEFSLLELLVSRSGEPFSRAEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVPK
GEE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=243, Percent_Identity=42.798353909465, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=41.304347826087, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786784, Length=236, Percent_Identity=38.9830508474576, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=41.4096916299559, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=37.8260869565217, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=34.5132743362832, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=41.3793103448276, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=39.4849785407725, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=35.2173913043478, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.3144104803493, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.3612334801762, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=35.4978354978355, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.0434782608696, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.5126050420168, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788550, Length=135, Percent_Identity=35.5555555555556, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=38.5964912280702, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=35.2941176470588, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=34.6534653465347, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=120, Percent_Identity=36.6666666666667, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788191, Length=127, Percent_Identity=31.496062992126, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788905, Length=236, Percent_Identity=25.8474576271186, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=121, Percent_Identity=37.1900826446281, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788192, Length=107, Percent_Identity=37.3831775700935, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27557; Mature: 27557

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTAADGEEALEVFRKQDPDLVVLDVMM
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCEEEEEEEC
PKLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSV
CCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHH
LRRVARSSHEGIPSSGVIQVGDLRIDTNKRQVYKRDERIRLTGMEFSLLELLVSRSGEPF
HHHHHHHHCCCCCCCCCEEECCEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCH
SRAEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVPK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCC
GEE
CCC
>Mature Secondary Structure
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTAADGEEALEVFRKQDPDLVVLDVMM
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCEEEEEEEC
PKLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSV
CCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHH
LRRVARSSHEGIPSSGVIQVGDLRIDTNKRQVYKRDERIRLTGMEFSLLELLVSRSGEPF
HHHHHHHHCCCCCCCCCEEECCEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCH
SRAEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVPK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCC
GEE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]