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The map label for this gene is argJ

Identifier: 86606004

GI number: 86606004

Start: 1341633

End: 1342853

Strand: Reverse

Name: argJ

Synonym: CYA_1327

Alternate gene names: 86606004

Gene position: 1342853-1341633 (Counterclockwise)

Preceding gene: 86606007

Following gene: 86606002

Centisome position: 45.79

GC content: 63.47

Gene sequence:

>1221_bases
ATGGGATCCCAATTTAAACGGGTTGCAGGCGCCGTTACCGCCCCGCGAGGGTTCCGCGCTGCTGGCGTGGCTGCTGGCCT
CAAGCCCTCCGGCGCTGCCGATCTCGCCCTAATTGTTTCCGACTGCGAGGCGGTGGGGGCTGGCGTTTTCACCAGCAACC
AGGTCAAGGCCGCCTGTGTTACCTACAACCAAGGGATCCTCGCCCAAGGGCAGCCGGTGCGGGCCATTCTCTGCAATGCC
GGCCAAGCCAACGCCTGTACAGGAGAAGAGGGGGAGCGCAACAACGCCCAACTGGCCCTCTGGGTAGGAGAACGGCTGGG
GATCCCGGCCCAACAGGTGCTCACTGCCTCGACAGGGGTGATCGGGCGGCAATTGGAAATGGCCAAAATCGAGGCGGCCC
TGCCCCGCCTGATCGACAGCCTCTCGCCGACAGGAGGAGAGAGCGCCGCCCGCGCCATCCTCACCACCGACCTGGTGACC
AAGAGTACAGCCCTGGAGGCCGAGATCGACGGCTACACCGTCAGGCTGGGAGGCATCGCCAAGGGATCCGGTATGATCCA
CCCCAACTTGGCGACGATGTTAGCTTTCCTAACCTGCGATGCAGCCGTGGATCCTCCCCTCTGGCAGCAGATCCTCAAAG
AGGCGGTTGACCTCAGCTTTAACCAAATCACCGTGGACGGGGATACCAGCACCAACGACATGGTGCTGGCTCTGGCCAAC
GGCCAAAGTGGGATTCCCACCCTGCAAGCTGGCACGAGAGCTGCCCAAGCCCTCGCCGAGATGGTTGTCCAGGTTTGCAT
TCACCTGGCTAAGGCCATCGCCCGCGACGGCGAGGGAGCCACCAAGTTGTTGCAGATCCGGGTGCAGGGCGCCCCCGACG
ACAGGTCAGCTCGGCAGATAGCCCGTGTCATTGCCAGCTCTCCCCTGGTGAAGGCGGCAGTTTTTGGCAACGATCCCAAC
TGGGGCCGGGTGGCCGCCGCCGCCGGACGGGCTGGGATCCCCTTTGACAGCCGTCGCTTGGAGGTTCGCCTGGGGGATTT
TCTGCTGCTGCAGGGGGGAATGCCTCTGGCTTTTGATCGCCAGGCGGCCTCTGAGTACCTAAAGAGAGGGGATCCCGTAA
CCTTTACGGTAGACCTCCACCAGGGATCTGGCCAGGGCGTTGCCTGGGGCTGTGACCTCAGCTACGACTACGTGCGCATC
AACGCCGAGTACACCACCTAG

Upstream 100 bases:

>100_bases
TTCTCGGGCAAAACTTGCCAGTTGCCAACCCTGGCCCTCAACCCCGATCTGAGCGCCAAGCCGGTATGATAGTGCCGATC
ACCCCCTGGCCCCAGAATCT

Downstream 100 bases:

>100_bases
ACAGCCCGCGGCAGCCAGGAGCCCTAGAAGCTGAGGCTCTCCCAGGAGACGTTGATGTCTTCCAGGAGCAGCGACTTGTT
GTAGATCTGCAGGATGATCA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MGSQFKRVAGAVTAPRGFRAAGVAAGLKPSGAADLALIVSDCEAVGAGVFTSNQVKAACVTYNQGILAQGQPVRAILCNA
GQANACTGEEGERNNAQLALWVGERLGIPAQQVLTASTGVIGRQLEMAKIEAALPRLIDSLSPTGGESAARAILTTDLVT
KSTALEAEIDGYTVRLGGIAKGSGMIHPNLATMLAFLTCDAAVDPPLWQQILKEAVDLSFNQITVDGDTSTNDMVLALAN
GQSGIPTLQAGTRAAQALAEMVVQVCIHLAKAIARDGEGATKLLQIRVQGAPDDRSARQIARVIASSPLVKAAVFGNDPN
WGRVAAAAGRAGIPFDSRRLEVRLGDFLLLQGGMPLAFDRQAASEYLKRGDPVTFTVDLHQGSGQGVAWGCDLSYDYVRI
NAEYTT

Sequences:

>Translated_406_residues
MGSQFKRVAGAVTAPRGFRAAGVAAGLKPSGAADLALIVSDCEAVGAGVFTSNQVKAACVTYNQGILAQGQPVRAILCNA
GQANACTGEEGERNNAQLALWVGERLGIPAQQVLTASTGVIGRQLEMAKIEAALPRLIDSLSPTGGESAARAILTTDLVT
KSTALEAEIDGYTVRLGGIAKGSGMIHPNLATMLAFLTCDAAVDPPLWQQILKEAVDLSFNQITVDGDTSTNDMVLALAN
GQSGIPTLQAGTRAAQALAEMVVQVCIHLAKAIARDGEGATKLLQIRVQGAPDDRSARQIARVIASSPLVKAAVFGNDPN
WGRVAAAAGRAGIPFDSRRLEVRLGDFLLLQGGMPLAFDRQAASEYLKRGDPVTFTVDLHQGSGQGVAWGCDLSYDYVRI
NAEYTT
>Mature_405_residues
GSQFKRVAGAVTAPRGFRAAGVAAGLKPSGAADLALIVSDCEAVGAGVFTSNQVKAACVTYNQGILAQGQPVRAILCNAG
QANACTGEEGERNNAQLALWVGERLGIPAQQVLTASTGVIGRQLEMAKIEAALPRLIDSLSPTGGESAARAILTTDLVTK
STALEAEIDGYTVRLGGIAKGSGMIHPNLATMLAFLTCDAAVDPPLWQQILKEAVDLSFNQITVDGDTSTNDMVLALANG
QSGIPTLQAGTRAAQALAEMVVQVCIHLAKAIARDGEGATKLLQIRVQGAPDDRSARQIARVIASSPLVKAAVFGNDPNW
GRVAAAAGRAGIPFDSRRLEVRLGDFLLLQGGMPLAFDRQAASEYLKRGDPVTFTVDLHQGSGQGVAWGCDLSYDYVRIN
AEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=417, Percent_Identity=34.7721822541966, Blast_Score=221, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42281; Mature: 42149

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSQFKRVAGAVTAPRGFRAAGVAAGLKPSGAADLALIVSDCEAVGAGVFTSNQVKAACV
CCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEEEECHHHHCCCCEECCCEEEEEE
TYNQGILAQGQPVRAILCNAGQANACTGEEGERNNAQLALWVGERLGIPAQQVLTASTGV
EECCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCC
IGRQLEMAKIEAALPRLIDSLSPTGGESAARAILTTDLVTKSTALEAEIDGYTVRLGGIA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCEE
KGSGMIHPNLATMLAFLTCDAAVDPPLWQQILKEAVDLSFNQITVDGDTSTNDMVLALAN
CCCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEC
GQSGIPTLQAGTRAAQALAEMVVQVCIHLAKAIARDGEGATKLLQIRVQGAPDDRSARQI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHH
ARVIASSPLVKAAVFGNDPNWGRVAAAAGRAGIPFDSRRLEVRLGDFLLLQGGMPLAFDR
HHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEECCEEEEECCCCCEECH
QAASEYLKRGDPVTFTVDLHQGSGQGVAWGCDLSYDYVRINAEYTT
HHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCEEEEEEEEEECC
>Mature Secondary Structure 
GSQFKRVAGAVTAPRGFRAAGVAAGLKPSGAADLALIVSDCEAVGAGVFTSNQVKAACV
CCHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEEEECHHHHCCCCEECCCEEEEEE
TYNQGILAQGQPVRAILCNAGQANACTGEEGERNNAQLALWVGERLGIPAQQVLTASTGV
EECCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCC
IGRQLEMAKIEAALPRLIDSLSPTGGESAARAILTTDLVTKSTALEAEIDGYTVRLGGIA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCEE
KGSGMIHPNLATMLAFLTCDAAVDPPLWQQILKEAVDLSFNQITVDGDTSTNDMVLALAN
CCCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEC
GQSGIPTLQAGTRAAQALAEMVVQVCIHLAKAIARDGEGATKLLQIRVQGAPDDRSARQI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHH
ARVIASSPLVKAAVFGNDPNWGRVAAAAGRAGIPFDSRRLEVRLGDFLLLQGGMPLAFDR
HHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEECCEEEEECCCCCEECH
QAASEYLKRGDPVTFTVDLHQGSGQGVAWGCDLSYDYVRINAEYTT
HHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]