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The map label for this gene is ubiA

Identifier: 86605727

GI number: 86605727

Start: 1049194

End: 1050096

Strand: Reverse

Name: ubiA

Synonym: CYA_1031

Alternate gene names: 86605727

Gene position: 1050096-1049194 (Counterclockwise)

Preceding gene: 86605729

Following gene: 86605723

Centisome position: 35.81

GC content: 64.01

Gene sequence:

>903_bases
ATGTCTGCCTCTCCTTCTGCACTCTGGGCCACTGGCGGAGCGATTTTACGGCTGTTGCGCTGGCATAAGCCGGCAGGGCG
GCTGATCCTGATGATCCCGGCTTTGTGGGGGGCTTTTCTGGCCGGACGGGGAACGCCGCCTTGGCCGCTGGTGGGGATCC
TGATTTTGGGCAGCTTGGCCACCAGCGGGGCGGGCTGTGTGATCAACGACCTCTGGGATCGGGATTTGGATCCCTTGGTG
GAGCGCACCCGCAACCGCCCCTTGGCCAGCCGCGAACTGACCGTTGCCGTCGGCATCGTGATGGCGCTGCTGACCTTGGC
CTGTGCGGCGGGGCTGGCGCTTTTTCTCAACCCGGTCAGCTTTGCCCTCTGCGTGGCGGCAGTGCCGGTGATCCTGCTCT
ATCCGGGGGCTAAGCGGGTGTTTCCCGTGCCCCAACTGGTGCTAGCCCTGGCCTGGGGATTTGCCGTGCTCATCAGTTGG
ACAGCGGTGAGCGGCCAAGATCCCCACACACCCCTGTGGGAGGAGGGGCTGGGCTGGCTGTGGCTGGCCACGGTGTTGTG
GACGTTGGGGTTCGATACGGTCTATGCTCTATCGGATCGAGAGGACGACGAACGGGCCGGGATCCACTCCAGCGCCCGCT
TTTTTGGGAGACAAACCCCAACGGCGGTGGGGCTGTTTTTCTTGGGCGCCGCCCTTGCCCTCTTGGGGGTGGGGATCAGC
CTGCAGTTGCACGCGGTCTATTTCCTTAGCCTGGCAGTTGCCGCCGCTCTCTGGGGCCGGCAAACCTGGCAGCTTCACCA
GGTCAATCCCCCTCCCACTCTCTACATGGCCATCTTCGGCCAAAACGTCCTCCAGGGCTTCATTCTCTTGGCAGGGATGA
TCGCCGGATCCCTGCTGGCCTGA

Upstream 100 bases:

>100_bases
AGGGGGACGACAAGGGTTCCAGGGCGGGCCAGTTTAGGATGATTTAAGATCGGTGCGGAGCTCCATTCCTCTCGGCAACT
GGCCCTCTTTCGACCTGGCT

Downstream 100 bases:

>100_bases
GGAACCCTGGCTGGAGCTAGTTGGGATAGATGCGCAGGCGGCGGTTGGGCTCTTCGCCGAAGCTCTGGGCCCGCAGGTGA
TAGTGCTCCACTAGCTGGTG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSASPSALWATGGAILRLLRWHKPAGRLILMIPALWGAFLAGRGTPPWPLVGILILGSLATSGAGCVINDLWDRDLDPLV
ERTRNRPLASRELTVAVGIVMALLTLACAAGLALFLNPVSFALCVAAVPVILLYPGAKRVFPVPQLVLALAWGFAVLISW
TAVSGQDPHTPLWEEGLGWLWLATVLWTLGFDTVYALSDREDDERAGIHSSARFFGRQTPTAVGLFFLGAALALLGVGIS
LQLHAVYFLSLAVAAALWGRQTWQLHQVNPPPTLYMAIFGQNVLQGFILLAGMIAGSLLA

Sequences:

>Translated_300_residues
MSASPSALWATGGAILRLLRWHKPAGRLILMIPALWGAFLAGRGTPPWPLVGILILGSLATSGAGCVINDLWDRDLDPLV
ERTRNRPLASRELTVAVGIVMALLTLACAAGLALFLNPVSFALCVAAVPVILLYPGAKRVFPVPQLVLALAWGFAVLISW
TAVSGQDPHTPLWEEGLGWLWLATVLWTLGFDTVYALSDREDDERAGIHSSARFFGRQTPTAVGLFFLGAALALLGVGIS
LQLHAVYFLSLAVAAALWGRQTWQLHQVNPPPTLYMAIFGQNVLQGFILLAGMIAGSLLA
>Mature_299_residues
SASPSALWATGGAILRLLRWHKPAGRLILMIPALWGAFLAGRGTPPWPLVGILILGSLATSGAGCVINDLWDRDLDPLVE
RTRNRPLASRELTVAVGIVMALLTLACAAGLALFLNPVSFALCVAAVPVILLYPGAKRVFPVPQLVLALAWGFAVLISWT
AVSGQDPHTPLWEEGLGWLWLATVLWTLGFDTVYALSDREDDERAGIHSSARFFGRQTPTAVGLFFLGAALALLGVGISL
QLHAVYFLSLAVAAALWGRQTWQLHQVNPPPTLYMAIFGQNVLQGFILLAGMIAGSLLA

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=286, Percent_Identity=33.2167832167832, Blast_Score=138, Evalue=5e-33,
Organism=Escherichia coli, GI1790473, Length=282, Percent_Identity=34.0425531914894, Blast_Score=124, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17553718, Length=290, Percent_Identity=34.1379310344828, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32565247, Length=290, Percent_Identity=33.1034482758621, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17553720, Length=342, Percent_Identity=29.8245614035088, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32565245, Length=138, Percent_Identity=39.1304347826087, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=39.1304347826087, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=210, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=32.6315789473684, Blast_Score=131, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32072; Mature: 31941

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASPSALWATGGAILRLLRWHKPAGRLILMIPALWGAFLAGRGTPPWPLVGILILGSLA
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TSGAGCVINDLWDRDLDPLVERTRNRPLASRELTVAVGIVMALLTLACAAGLALFLNPVS
CCCCCCEEHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALCVAAVPVILLYPGAKRVFPVPQLVLALAWGFAVLISWTAVSGQDPHTPLWEEGLGWL
HHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHH
WLATVLWTLGFDTVYALSDREDDERAGIHSSARFFGRQTPTAVGLFFLGAALALLGVGIS
HHHHHHHHHCHHHEEEECCCCCHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
LQLHAVYFLSLAVAAALWGRQTWQLHQVNPPPTLYMAIFGQNVLQGFILLAGMIAGSLLA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASPSALWATGGAILRLLRWHKPAGRLILMIPALWGAFLAGRGTPPWPLVGILILGSLA
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TSGAGCVINDLWDRDLDPLVERTRNRPLASRELTVAVGIVMALLTLACAAGLALFLNPVS
CCCCCCEEHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALCVAAVPVILLYPGAKRVFPVPQLVLALAWGFAVLISWTAVSGQDPHTPLWEEGLGWL
HHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHH
WLATVLWTLGFDTVYALSDREDDERAGIHSSARFFGRQTPTAVGLFFLGAALALLGVGIS
HHHHHHHHHCHHHEEEECCCCCHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
LQLHAVYFLSLAVAAALWGRQTWQLHQVNPPPTLYMAIFGQNVLQGFILLAGMIAGSLLA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA