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The map label for this gene is msrB

Identifier: 86605723

GI number: 86605723

Start: 1044863

End: 1045273

Strand: Reverse

Name: msrB

Synonym: CYA_1027

Alternate gene names: 86605723

Gene position: 1045273-1044863 (Counterclockwise)

Preceding gene: 86605727

Following gene: 86605722

Centisome position: 35.64

GC content: 57.42

Gene sequence:

>411_bases
ATGGCTCAAGAAATCTATCCCGTTACCAAAACCGACGCTGAGTGGCGACAACTGCTCACCGAAGAGCAGTACTATGTGCT
GCGCCAAGAGGGAACCGAGCCCCCCTTCCGCAACGCCTACTACGACAACAAGGCTCCAGGGATCTATGTCTGCGCTGGCT
GTGGGCAGGAGCTCTTTTCCTCGGCAGCCAAATACGACAGTGGCACTGGTTGGCCCAGTTTTTGGGAGCCGATTGCTCCT
CATGTGATCGGCACCAAGACGGATTGGAAGTTGCTTGTGCCTCGCACCGAGGTTCACTGCTCCAACTGTGGTGGTCACTT
AGGGCACGTGTTTCGGGACGGTCCCCCACCAACGGGTCTGCGCTACTGCATCAACTCTGCTGCTCTGAAGTTCATCCCCG
CCACCACCTGA

Upstream 100 bases:

>100_bases
TCAGGACGGACAAACCGCTTATGCGACGAGGCAAGCTTTTGACTTGACAGTGGCCGGGTTCGTTACGGCACCCCTCAGCT
TGACAGGAGAGCAACAGGCG

Downstream 100 bases:

>100_bases
GCCTCTCCTCAGGCAACGCTAGAATTGAGCCACCTGCCTGGGTGAACCTATGTCGGACTACACCTTTTTGGATGCTGCCT
CGATTTTGCTGCGGGAGGGT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MAQEIYPVTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIYVCAGCGQELFSSAAKYDSGTGWPSFWEPIAP
HVIGTKTDWKLLVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAALKFIPATT

Sequences:

>Translated_136_residues
MAQEIYPVTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIYVCAGCGQELFSSAAKYDSGTGWPSFWEPIAP
HVIGTKTDWKLLVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAALKFIPATT
>Mature_135_residues
AQEIYPVTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIYVCAGCGQELFSSAAKYDSGTGWPSFWEPIAPH
VIGTKTDWKLLVPRTEVHCSNCGGHLGHVFRDGPPPTGLRYCINSAALKFIPATT

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=129, Percent_Identity=50.3875968992248, Blast_Score=135, Evalue=8e-33,
Organism=Homo sapiens, GI301336162, Length=129, Percent_Identity=50.3875968992248, Blast_Score=135, Evalue=8e-33,
Organism=Homo sapiens, GI73089054, Length=129, Percent_Identity=50.3875968992248, Blast_Score=135, Evalue=8e-33,
Organism=Homo sapiens, GI37620216, Length=129, Percent_Identity=50.3875968992248, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=53.125, Blast_Score=129, Evalue=8e-31,
Organism=Homo sapiens, GI7706511, Length=98, Percent_Identity=41.8367346938776, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788077, Length=118, Percent_Identity=50.8474576271186, Blast_Score=129, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=133, Percent_Identity=43.609022556391, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=43.609022556391, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=40.9448818897638, Blast_Score=105, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221378664, Length=137, Percent_Identity=43.7956204379562, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221378662, Length=144, Percent_Identity=42.3611111111111, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24645799, Length=140, Percent_Identity=44.2857142857143, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI45553335, Length=135, Percent_Identity=44.4444444444444, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21356369, Length=135, Percent_Identity=44.4444444444444, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24645801, Length=151, Percent_Identity=42.3841059602649, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24645804, Length=146, Percent_Identity=42.4657534246575, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15198; Mature: 15067

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQEIYPVTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIYVCAGCGQELFS
CCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHHHH
SAAKYDSGTGWPSFWEPIAPHVIGTKTDWKLLVPRTEVHCSNCGGHLGHVFRDGPPPTGL
HHHCCCCCCCCCCHHHHCCCCEECCCCCCEEECCCCEECCCCCCCHHHHHHCCCCCCHHH
RYCINSAALKFIPATT
HHHHHHHHHEEECCCC
>Mature Secondary Structure 
AQEIYPVTKTDAEWRQLLTEEQYYVLRQEGTEPPFRNAYYDNKAPGIYVCAGCGQELFS
CCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHHHH
SAAKYDSGTGWPSFWEPIAPHVIGTKTDWKLLVPRTEVHCSNCGGHLGHVFRDGPPPTGL
HHHCCCCCCCCCCHHHHCCCCEECCCCCCEEECCCCEECCCCCCCHHHHHHCCCCCCHHH
RYCINSAALKFIPATT
HHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]