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The map label for this gene is rnc

Identifier: 86605510

GI number: 86605510

Start: 816711

End: 817436

Strand: Reverse

Name: rnc

Synonym: CYA_0804

Alternate gene names: 86605510

Gene position: 817436-816711 (Counterclockwise)

Preceding gene: 86605512

Following gene: 86605509

Centisome position: 27.87

GC content: 61.71

Gene sequence:

>726_bases
ATGGTTGAGCCGATCCCACCTCGTCGCCGCGCCTTAGAGCACCTGCTGAACCGGTTGGGGTTCAAGGATCCCGCCTGGCT
GGAGCAACTGCGCTGGGATCTGTTGGATCAAGCTTTGATTCACCCTTCTCTGGATGGCCAGCGCAACAACGACCGGCTGG
AGTTCTTAGGGGATTCTGTCCTGCGCATTTTGGCCACTGAGTTCTTGTTCCAGTCCTATCCCCACTTGTCGGTGGGAGAG
CTGACCGCAGTTCGCTCGGATCTGATCAGCGATGCCCACCTGGCGGAACTGGCGGATCTGCATGGCCTAGAGCGCTACCT
TGAGGTGGGATCCAGCTCCCAAAACGACCTGGCCGGACGGGAGCGGCGCTTAGCCGATGCTTTTGAGGCGGTGTTGGGAT
CCCTATACCTGAGCTGGGGCATGCACACCCTGGCCCGGCTGCATCCTTGGCTGGATCCCTACTTTCGCCAACGGGTGGAG
CAGTGGTTCCAGGATCCCACTCGGCGCAACCCGAAAGCCGCGCTGCAGGAACTGACCCAACGCCTATGGGGCACCTTGCC
GGAATATCGTCTGGTGGCTGCCCGGGAACACCCGCCGCACTTCACCATGGAAGTTTGGGGCCACGGCCAATGTTGGGGCC
GCGGCGAGGGGCGCTCCAAAAAGGCGGCAGAAATGGCCGCTGCGGCCCAAGCCTACGGGCACTTGCAGTCGCAGGAAATA
AGGTAG

Upstream 100 bases:

>100_bases
GGCATGCATGCAGGGATCCTCTCCAAAGGCTTATACTACTCCTGTAGCACAAGGTGAGCACTGAGAGCATTCTAGGTGTA
GAGATTTTGCCGCAGGTTTT

Downstream 100 bases:

>100_bases
GCGCCACTACGAGGCGCTCCATGGGTGGCAACCGCTGTGGTAGCCGGCCTCTGCTTCCGGCACCGCCAGCCCGCTTCTAC
GGGGAGTTCTCGCCTCATCT

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III 2; RNase III 2 [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MVEPIPPRRRALEHLLNRLGFKDPAWLEQLRWDLLDQALIHPSLDGQRNNDRLEFLGDSVLRILATEFLFQSYPHLSVGE
LTAVRSDLISDAHLAELADLHGLERYLEVGSSSQNDLAGRERRLADAFEAVLGSLYLSWGMHTLARLHPWLDPYFRQRVE
QWFQDPTRRNPKAALQELTQRLWGTLPEYRLVAAREHPPHFTMEVWGHGQCWGRGEGRSKKAAEMAAAAQAYGHLQSQEI
R

Sequences:

>Translated_241_residues
MVEPIPPRRRALEHLLNRLGFKDPAWLEQLRWDLLDQALIHPSLDGQRNNDRLEFLGDSVLRILATEFLFQSYPHLSVGE
LTAVRSDLISDAHLAELADLHGLERYLEVGSSSQNDLAGRERRLADAFEAVLGSLYLSWGMHTLARLHPWLDPYFRQRVE
QWFQDPTRRNPKAALQELTQRLWGTLPEYRLVAAREHPPHFTMEVWGHGQCWGRGEGRSKKAAEMAAAAQAYGHLQSQEI
R
>Mature_241_residues
MVEPIPPRRRALEHLLNRLGFKDPAWLEQLRWDLLDQALIHPSLDGQRNNDRLEFLGDSVLRILATEFLFQSYPHLSVGE
LTAVRSDLISDAHLAELADLHGLERYLEVGSSSQNDLAGRERRLADAFEAVLGSLYLSWGMHTLARLHPWLDPYFRQRVE
QWFQDPTRRNPKAALQELTQRLWGTLPEYRLVAAREHPPHFTMEVWGHGQCWGRGEGRSKKAAEMAAAAQAYGHLQSQEI
R

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030234, Length=190, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI155030236, Length=190, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1788920, Length=194, Percent_Identity=31.4432989690722, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323895, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17137682, Length=192, Percent_Identity=31.25, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 27742; Mature: 27742

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]