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The map label for this gene is pyrR

Identifier: 86605125

GI number: 86605125

Start: 421806

End: 422360

Strand: Reverse

Name: pyrR

Synonym: CYA_0406

Alternate gene names: 86605125

Gene position: 422360-421806 (Counterclockwise)

Preceding gene: 86605127

Following gene: 86605124

Centisome position: 14.4

GC content: 62.88

Gene sequence:

>555_bases
ATGTCCACAGTCGAGGTCTTCAATGCGCAGCAGATAGCGGAGCTGATCGACGCTCTGGCTACAGCAATTGCCAGGGATCA
CCCCCACCTGGACAGGCTGGTGTTGATCGGCATTCGCACTCGCGGCGTCCCCTTGGCCTACCGCCTGCGGGATCGCATCG
CCACCGGCTTCGGGAGCCCACCGCAGGTAGGAGAGCTGGACATCACCTTCTTCCGAGACGACCTGGGCTCCGGCGGCCTG
CGCACTCCCAATCGCAGCGAGCTGCCGCGGGATCTGACCGGCCAAGAAGTGGTGTTGGTGGACGATGTGCTCTTCCGGGG
TCGCACCGTCCGTGCGGCTCTGGAGGCTCTCAACCACTTTGGGCGACCGGAGCAAGTGCGCCTGGCCGTGTTGATCGACC
GCGGCCACCGCCAGTTTCCCATTCAACCAGACTACTGCGGTCACAAGCTAACCACGGCCCCTGAGCAGATCGTCAAAGTG
CACCTGCGGGAAACCGACGGCGAGGAGCGGGTGTTGTTGATCGACGCCAAACTTGAGGAAAACAGCAGAGAGTGA

Upstream 100 bases:

>100_bases
TCTTACTTTTATCCTACTGGATGGGGATCCCGCCGGTAGATTGGGCTAATTTGGGCTTTTATAAGCTGAGTCCCAACTGG
CGAGGGGGGGACAGGGATCC

Downstream 100 bases:

>100_bases
GCCTGAGACGCCCCTGGGGTGCGGTATGGTGGGGATAATCTGCCGACTTTTGCCGCTATGGCTGTCTTGCCGGAAACCCG
TCGCTACGCTGTCTTGGGCA

Product: pyrR bifunctional protein

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSTVEVFNAQQIAELIDALATAIARDHPHLDRLVLIGIRTRGVPLAYRLRDRIATGFGSPPQVGELDITFFRDDLGSGGL
RTPNRSELPRDLTGQEVVLVDDVLFRGRTVRAALEALNHFGRPEQVRLAVLIDRGHRQFPIQPDYCGHKLTTAPEQIVKV
HLRETDGEERVLLIDAKLEENSRE

Sequences:

>Translated_184_residues
MSTVEVFNAQQIAELIDALATAIARDHPHLDRLVLIGIRTRGVPLAYRLRDRIATGFGSPPQVGELDITFFRDDLGSGGL
RTPNRSELPRDLTGQEVVLVDDVLFRGRTVRAALEALNHFGRPEQVRLAVLIDRGHRQFPIQPDYCGHKLTTAPEQIVKV
HLRETDGEERVLLIDAKLEENSRE
>Mature_183_residues
STVEVFNAQQIAELIDALATAIARDHPHLDRLVLIGIRTRGVPLAYRLRDRIATGFGSPPQVGELDITFFRDDLGSGGLR
TPNRSELPRDLTGQEVVLVDDVLFRGRTVRAALEALNHFGRPEQVRLAVLIDRGHRQFPIQPDYCGHKLTTAPEQIVKVH
LRETDGEERVLLIDAKLEENSRE

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_SYNJA (Q2JX67)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_473888.1
- ProteinModelPortal:   Q2JX67
- SMR:   Q2JX67
- STRING:   Q2JX67
- GeneID:   3897920
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0406
- TIGR:   CYA_0406
- eggNOG:   COG2065
- HOGENOM:   HBG641958
- OMA:   ELDITFF
- ProtClustDB:   CLSK750136
- BioCyc:   SSP321327:CYA_0406-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20644; Mature: 20513

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVEVFNAQQIAELIDALATAIARDHPHLDRLVLIGIRTRGVPLAYRLRDRIATGFGSP
CCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCC
PQVGELDITFFRDDLGSGGLRTPNRSELPRDLTGQEVVLVDDVLFRGRTVRAALEALNHF
CCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHC
GRPEQVRLAVLIDRGHRQFPIQPDYCGHKLTTAPEQIVKVHLRETDGEERVLLIDAKLEE
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEEHHCCCCCCCEEEEEEEECCC
NSRE
CCCC
>Mature Secondary Structure 
STVEVFNAQQIAELIDALATAIARDHPHLDRLVLIGIRTRGVPLAYRLRDRIATGFGSP
CCHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCC
PQVGELDITFFRDDLGSGGLRTPNRSELPRDLTGQEVVLVDDVLFRGRTVRAALEALNHF
CCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHC
GRPEQVRLAVLIDRGHRQFPIQPDYCGHKLTTAPEQIVKVHLRETDGEERVLLIDAKLEE
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEEHHCCCCCCCEEEEEEEECCC
NSRE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA