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The map label for this gene is trpB

Identifier: 86605059

GI number: 86605059

Start: 357668

End: 358867

Strand: Reverse

Name: trpB

Synonym: CYA_0339

Alternate gene names: 86605059

Gene position: 358867-357668 (Counterclockwise)

Preceding gene: 86605065

Following gene: 86605058

Centisome position: 12.24

GC content: 64.75

Gene sequence:

>1200_bases
GTGCGTCCGGATCCTCGGGGCCGGTTTGGGCCCTTTGGGGGCCGTTTTGTGCCGGAAACCCTGATGAGCGCCCTGACGGA
GCTGGAGGAAGCCTTTGAGCAGCATTGGCGGGATCCCGAGTTTCGCGCCGAGTTCCACAGCTTGTTGCGGGATTTTGTCG
GTCGGCCCAGCCCCCTCTACTTTGCCCAGCGGCTGACCGAGCACTACGACGGCCCCCAGATCTACCTCAAGCGCGAAGAC
CTCAACCACACCGGCGCCCACAAGATCAACAACGCCCTCGGCCAAGTGCTGCTGGCGGTGCGCATGGGCAAGCGGCGGAT
CATCGCCGAGACTGGCGCTGGCCAGCATGGGGTGGCCACGGCAACGGTGTGTGCTCGTTTTGGGTTGGAATGCGTCATCT
ACATGGGGGCAGTGGACATGGAGCGGCAGGCCCCCAATGTGCAGCGGATGCGCCTGCTGGGCGCTGAGGTAAGGGGGGTC
GAATCAGGCACAGCCACCCTCAAAGACGCCCTCTCCGAGGCCATCCGCGACTGGGTAACCAACGTGGAGACCACCCACTA
CGTCATTGGCACGGTGGCCGGACCCCACCCCTACCCGAAGCTGGTGCGGACCTTTCACGATGTCATCGGCCAGGAGACGC
GGCAGCAGTGTCAGGAGAAATGGGGAGGGCTGCCAGACGTGTTGCTGGCCTGTGTGGGCGGCGGCTCCAATGCCCTGGGT
CTGTTCAACGAGTTTGTCCGCGATCCCCAGGTGCGGCTCATCGGCATCGAGGCTGCCGGGGAGGGCTTACACACCTCCCG
CCACGCCGCCACCCTCAGCCGCGGTCGCGTTGGGGTCTTGCACGGGGCCATGAGCTACCTGCTGCAAGATGAAGAAGGCC
AGGTGCAGGAGGCCCATTCCATCAGCGCCGGCTTGGATTACCCCGGCGTGGGGCCGGAGCACAGCTACTTAAAAGCAATT
GGGCGAGCCGAGTACTACGCCGTTACCGACGACGAGGCGGTAGAGGCGCTGCTGCTGCTGTCGCGCCTGGAGGGGATCAT
CCCGGCTTTGGAGACGGCCCATGCCCTGGCCTACCTGAAGACTTTGGCCCCCCAGCTTGGCCCCCAGCAGCGGGTGGTGG
TCAACTGCTCCGGGCGGGGCGACAAGGATCTGAACACCGTTTTCAAGTACTTGCAGAAGCGGGGGCATAGCCTAGCCTAG

Upstream 100 bases:

>100_bases
CTTGTCTCCTATTGCCGGCTGTCAAGCCCGCGCCAATCCATTTGCCATGACCTCAACTCCTCTTGCTGCCCCTGCCACCT
GGGATCCCCTTGACCCGCAG

Downstream 100 bases:

>100_bases
AGTTGGGTTGGCAAGATCCTCAGCTCGTGTCCACCTTTGCCATTCGATCGCTCAGCCTGCTGGCCTTGTTTCTGGGGGCA
GGGCTAGGGCTGCTGGCCGG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MRPDPRGRFGPFGGRFVPETLMSALTELEEAFEQHWRDPEFRAEFHSLLRDFVGRPSPLYFAQRLTEHYDGPQIYLKRED
LNHTGAHKINNALGQVLLAVRMGKRRIIAETGAGQHGVATATVCARFGLECVIYMGAVDMERQAPNVQRMRLLGAEVRGV
ESGTATLKDALSEAIRDWVTNVETTHYVIGTVAGPHPYPKLVRTFHDVIGQETRQQCQEKWGGLPDVLLACVGGGSNALG
LFNEFVRDPQVRLIGIEAAGEGLHTSRHAATLSRGRVGVLHGAMSYLLQDEEGQVQEAHSISAGLDYPGVGPEHSYLKAI
GRAEYYAVTDDEAVEALLLLSRLEGIIPALETAHALAYLKTLAPQLGPQQRVVVNCSGRGDKDLNTVFKYLQKRGHSLA

Sequences:

>Translated_399_residues
MRPDPRGRFGPFGGRFVPETLMSALTELEEAFEQHWRDPEFRAEFHSLLRDFVGRPSPLYFAQRLTEHYDGPQIYLKRED
LNHTGAHKINNALGQVLLAVRMGKRRIIAETGAGQHGVATATVCARFGLECVIYMGAVDMERQAPNVQRMRLLGAEVRGV
ESGTATLKDALSEAIRDWVTNVETTHYVIGTVAGPHPYPKLVRTFHDVIGQETRQQCQEKWGGLPDVLLACVGGGSNALG
LFNEFVRDPQVRLIGIEAAGEGLHTSRHAATLSRGRVGVLHGAMSYLLQDEEGQVQEAHSISAGLDYPGVGPEHSYLKAI
GRAEYYAVTDDEAVEALLLLSRLEGIIPALETAHALAYLKTLAPQLGPQQRVVVNCSGRGDKDLNTVFKYLQKRGHSLA
>Mature_399_residues
MRPDPRGRFGPFGGRFVPETLMSALTELEEAFEQHWRDPEFRAEFHSLLRDFVGRPSPLYFAQRLTEHYDGPQIYLKRED
LNHTGAHKINNALGQVLLAVRMGKRRIIAETGAGQHGVATATVCARFGLECVIYMGAVDMERQAPNVQRMRLLGAEVRGV
ESGTATLKDALSEAIRDWVTNVETTHYVIGTVAGPHPYPKLVRTFHDVIGQETRQQCQEKWGGLPDVLLACVGGGSNALG
LFNEFVRDPQVRLIGIEAAGEGLHTSRHAATLSRGRVGVLHGAMSYLLQDEEGQVQEAHSISAGLDYPGVGPEHSYLKAI
GRAEYYAVTDDEAVEALLLLSRLEGIIPALETAHALAYLKTLAPQLGPQQRVVVNCSGRGDKDLNTVFKYLQKRGHSLA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=388, Percent_Identity=56.701030927835, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321412, Length=389, Percent_Identity=58.8688946015424, Blast_Score=473, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43862; Mature: 43862

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDPRGRFGPFGGRFVPETLMSALTELEEAFEQHWRDPEFRAEFHSLLRDFVGRPSPLY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHH
FAQRLTEHYDGPQIYLKREDLNHTGAHKINNALGQVLLAVRMGKRRIIAETGAGQHGVAT
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHH
ATVCARFGLECVIYMGAVDMERQAPNVQRMRLLGAEVRGVESGTATLKDALSEAIRDWVT
HHHHHHHCCHHEEEECCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
NVETTHYVIGTVAGPHPYPKLVRTFHDVIGQETRQQCQEKWGGLPDVLLACVGGGSNALG
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHH
LFNEFVRDPQVRLIGIEAAGEGLHTSRHAATLSRGRVGVLHGAMSYLLQDEEGQVQEAHS
HHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH
ISAGLDYPGVGPEHSYLKAIGRAEYYAVTDDEAVEALLLLSRLEGIIPALETAHALAYLK
HHCCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAPQLGPQQRVVVNCSGRGDKDLNTVFKYLQKRGHSLA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRPDPRGRFGPFGGRFVPETLMSALTELEEAFEQHWRDPEFRAEFHSLLRDFVGRPSPLY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHH
FAQRLTEHYDGPQIYLKREDLNHTGAHKINNALGQVLLAVRMGKRRIIAETGAGQHGVAT
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHH
ATVCARFGLECVIYMGAVDMERQAPNVQRMRLLGAEVRGVESGTATLKDALSEAIRDWVT
HHHHHHHCCHHEEEECCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
NVETTHYVIGTVAGPHPYPKLVRTFHDVIGQETRQQCQEKWGGLPDVLLACVGGGSNALG
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHH
LFNEFVRDPQVRLIGIEAAGEGLHTSRHAATLSRGRVGVLHGAMSYLLQDEEGQVQEAHS
HHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH
ISAGLDYPGVGPEHSYLKAIGRAEYYAVTDDEAVEALLLLSRLEGIIPALETAHALAYLK
HHCCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAPQLGPQQRVVVNCSGRGDKDLNTVFKYLQKRGHSLA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA