Click here to switch to the map view.

The map label for this gene is atoC [H]

Identifier: 86604823

GI number: 86604823

Start: 90367

End: 91023

Strand: Reverse

Name: atoC [H]

Synonym: CYA_0093

Alternate gene names: 86604823

Gene position: 91023-90367 (Counterclockwise)

Preceding gene: 86604832

Following gene: 86604822

Centisome position: 3.1

GC content: 55.56

Gene sequence:

>657_bases
ATGACAGCCAAGACGGTGTTGGTCATTGACGATAGCATCATGATCCGCAAGATGGTGGCCAGCATCTTGGCTGACCAGTT
TCAGGTGCTGGAGGCCAAAGACGGCCTAGCGGGCCTGGAGGCTGCCAAAAAACATCACCCCGACCTGATCTTGCTGGATT
TTGTCATGCCCAAGATGGACGGCTATGACACATTGCAGGCCATCCGGCAGGAAGAGAGCCTGAAGAATACCCCTGTCATC
ATCATGTCGGGGATGAAAGAGCAGGTAACAGCCCGCGTCCCTGAGCCTTTTGTCGATTTCGATTTTATTGAAAAGCCGTT
TGAGGCGGAGGCTCTTCTGGCTCGCATTCAAAAGGCCCTGCAAGTAGCTCCTGCGGCGGCAGCAGAGCCGGGATCGGAAA
CCAACACTCAGTTGCTCTTGAACAAGCTCACCGCCATCGAGACGCTGCTCATCCAAGGTACGGAAAACCTTATCCAGCGG
GAAGTGGTGACGCGGCTTTCTGATCTCAACCAGCGCCTGGAGCGTCAGGAATCCCACAGCGCTAACCTGGAAGAGCAGAT
CCGTAAACTCACCAGCGAGGTGGAACGGCACAGCCAGGGCTTGGCCTTGATCGTCAAGGAGCTAAAGCACATCCGCAAGC
TGTTGGGGGGATCCTGA

Upstream 100 bases:

>100_bases
GTACTCTATTGGTGTCCCAGGAAGGACGCCTCTGATGCTTCATGCGCTGGAGGAAGAGGCTGAGCAGGTCGAGTAGATTG
GGAAAAGGGGGCGCCCGAGC

Downstream 100 bases:

>100_bases
TGTCTGAGAGGGTTTTTGAGCGCGCCTATCGGCACCTGGATGCGGTGACGGCCCTGTTTGTGGCTGTGCTGCTGATCTCC
AACATCGCCTCCACCAAGAT

Product: response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTAKTVLVIDDSIMIRKMVASILADQFQVLEAKDGLAGLEAAKKHHPDLILLDFVMPKMDGYDTLQAIRQEESLKNTPVI
IMSGMKEQVTARVPEPFVDFDFIEKPFEAEALLARIQKALQVAPAAAAEPGSETNTQLLLNKLTAIETLLIQGTENLIQR
EVVTRLSDLNQRLERQESHSANLEEQIRKLTSEVERHSQGLALIVKELKHIRKLLGGS

Sequences:

>Translated_218_residues
MTAKTVLVIDDSIMIRKMVASILADQFQVLEAKDGLAGLEAAKKHHPDLILLDFVMPKMDGYDTLQAIRQEESLKNTPVI
IMSGMKEQVTARVPEPFVDFDFIEKPFEAEALLARIQKALQVAPAAAAEPGSETNTQLLLNKLTAIETLLIQGTENLIQR
EVVTRLSDLNQRLERQESHSANLEEQIRKLTSEVERHSQGLALIVKELKHIRKLLGGS
>Mature_217_residues
TAKTVLVIDDSIMIRKMVASILADQFQVLEAKDGLAGLEAAKKHHPDLILLDFVMPKMDGYDTLQAIRQEESLKNTPVII
MSGMKEQVTARVPEPFVDFDFIEKPFEAEALLARIQKALQVAPAAAAEPGSETNTQLLLNKLTAIETLLIQGTENLIQRE
VVTRLSDLNQRLERQESHSANLEEQIRKLTSEVERHSQGLALIVKELKHIRKLLGGS

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=36.2903225806452, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1786599, Length=130, Percent_Identity=32.3076923076923, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24313; Mature: 24181

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTVLVIDDSIMIRKMVASILADQFQVLEAKDGLAGLEAAKKHHPDLILLDFVMPKMD
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEHHHHHCCCC
GYDTLQAIRQEESLKNTPVIIMSGMKEQVTARVPEPFVDFDFIEKPFEAEALLARIQKAL
CHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHH
QVAPAAAAEPGSETNTQLLLNKLTAIETLLIQGTENLIQREVVTRLSDLNQRLERQESHS
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANLEEQIRKLTSEVERHSQGLALIVKELKHIRKLLGGS
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAKTVLVIDDSIMIRKMVASILADQFQVLEAKDGLAGLEAAKKHHPDLILLDFVMPKMD
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEHHHHHCCCC
GYDTLQAIRQEESLKNTPVIIMSGMKEQVTARVPEPFVDFDFIEKPFEAEALLARIQKAL
CHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHH
QVAPAAAAEPGSETNTQLLLNKLTAIETLLIQGTENLIQREVVTRLSDLNQRLERQESHS
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANLEEQIRKLTSEVERHSQGLALIVKELKHIRKLLGGS
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]