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The map label for this gene is uppP

Identifier: 86604818

GI number: 86604818

Start: 86175

End: 87005

Strand: Reverse

Name: uppP

Synonym: CYA_0087

Alternate gene names: 86604818

Gene position: 87005-86175 (Counterclockwise)

Preceding gene: 86604819

Following gene: 86604815

Centisome position: 2.97

GC content: 62.94

Gene sequence:

>831_bases
GTGCTGGCCGATATCTGGTATCCCAACTGGTGGCAGGCCCTGGTCTTGGGCATGGTGCAAGGGATCACGGAATTTCTGCC
CATCAGCAGCACGGCGCACCTGCGGGTGTTTCCAGCTTTGCTGGGCTGGCCGGATGCGGGGGCTTCCTTTGCGGCGGTGA
TCCAATTGGGCAGCCTGGGAGCGGTGTTGATCTACTTTGCTTCTGACCTGCGCCAGTTGCTCCTCGGCTCCTGGAAGGCT
TGGCAGAAGCGAGATTTCCAGGAGGAGTCTTGGCGGCTGCTCATGGGGATCCTGGTGGGAACGCTGCCGATTGTCATAGC
GGGCTGGGCCGTCAAGGCCATCTGGGGATCCCCGCCCCGGCAGTTGTGGGTGGTTGCCGCCGCCGCCATCGGCTTGGCCC
TGGCTTTGGGCTGGGCAGAACGGGTGGGGAAGCGCCGGCGCGATCTGCACAGCCTGGGCATTGGGGATGGGCTCTGGGTG
GGGCTGGCCCAGGCTTTGGCCCTGATCCCAGGGGTATCCCGCTCTGGTGTGACGCTGACGGCGGCTCTGTTGCTCGATTT
GCAGCGCTCGGCTGCCGCCCGCTACTCCTTTTTGCTGGGGATCCCGGCCCTCTTTTTGGCCGGGGTGGCGGAGTTTATCG
CCGAGTTCAGGGCAGAGGCGCTGCTGTCGCAGGGGCTGGGGACGCTCTCGGCCTTTGTCTTCTCCTACGGGTCCATCGAC
TGGCTAATTCGATTTTTGCAGCGCAGCAGCACCTGGGTGTTCATTGTCTATCGGATTGGTTTTGGCCTGTTCATTTTCCT
GGGGCTGGCCCTGGGGTTTTTGCAACCTTAA

Upstream 100 bases:

>100_bases
GCGGCATCTCTATCTCCCCTCTCCCTAAGGGAGAGGGGTTGGGGGTGAGGGAAACTCCCCTCCAGACAGTAGCCTGGCGT
ACTGGGAGAGGCTTTCTTTG

Downstream 100 bases:

>100_bases
GTGGGCTTTTGTTGCCGCAGAATCCGCAGCGCTTTCGGCAGGTGCTCCGCCAGGTGGGCCGGATCCACGCCCGTTAGACC
CCGTTCCCCCGCCAAATGGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLADIWYPNWWQALVLGMVQGITEFLPISSTAHLRVFPALLGWPDAGASFAAVIQLGSLGAVLIYFASDLRQLLLGSWKA
WQKRDFQEESWRLLMGILVGTLPIVIAGWAVKAIWGSPPRQLWVVAAAAIGLALALGWAERVGKRRRDLHSLGIGDGLWV
GLAQALALIPGVSRSGVTLTAALLLDLQRSAAARYSFLLGIPALFLAGVAEFIAEFRAEALLSQGLGTLSAFVFSYGSID
WLIRFLQRSSTWVFIVYRIGFGLFIFLGLALGFLQP

Sequences:

>Translated_276_residues
MLADIWYPNWWQALVLGMVQGITEFLPISSTAHLRVFPALLGWPDAGASFAAVIQLGSLGAVLIYFASDLRQLLLGSWKA
WQKRDFQEESWRLLMGILVGTLPIVIAGWAVKAIWGSPPRQLWVVAAAAIGLALALGWAERVGKRRRDLHSLGIGDGLWV
GLAQALALIPGVSRSGVTLTAALLLDLQRSAAARYSFLLGIPALFLAGVAEFIAEFRAEALLSQGLGTLSAFVFSYGSID
WLIRFLQRSSTWVFIVYRIGFGLFIFLGLALGFLQP
>Mature_276_residues
MLADIWYPNWWQALVLGMVQGITEFLPISSTAHLRVFPALLGWPDAGASFAAVIQLGSLGAVLIYFASDLRQLLLGSWKA
WQKRDFQEESWRLLMGILVGTLPIVIAGWAVKAIWGSPPRQLWVVAAAAIGLALALGWAERVGKRRRDLHSLGIGDGLWV
GLAQALALIPGVSRSGVTLTAALLLDLQRSAAARYSFLLGIPALFLAGVAEFIAEFRAEALLSQGLGTLSAFVFSYGSID
WLIRFLQRSSTWVFIVYRIGFGLFIFLGLALGFLQP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=255, Percent_Identity=30.9803921568627, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SYNJA (Q2JXZ9)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_473581.1
- STRING:   Q2JXZ9
- GeneID:   3897116
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0087
- TIGR:   CYA_0087
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   DWQREEW
- ProtClustDB:   PRK00281
- BioCyc:   SSP321327:CYA_0087-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30083; Mature: 30083

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x107f18c8)-; HASH(0x120db3e8)-; HASH(0x11e57ea8)-; HASH(0x120d387c)-; HASH(0x120ee9a0)-; HASH(0x11e5aba4)-; HASH(0x127fba38)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLADIWYPNWWQALVLGMVQGITEFLPISSTAHLRVFPALLGWPDAGASFAAVIQLGSLG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHH
AVLIYFASDLRQLLLGSWKAWQKRDFQEESWRLLMGILVGTLPIVIAGWAVKAIWGSPPR
HHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QLWVVAAAAIGLALALGWAERVGKRRRDLHSLGIGDGLWVGLAQALALIPGVSRSGVTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
AALLLDLQRSAAARYSFLLGIPALFLAGVAEFIAEFRAEALLSQGLGTLSAFVFSYGSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHH
WLIRFLQRSSTWVFIVYRIGFGLFIFLGLALGFLQP
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA