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The map label for this gene is appC [H]

Identifier: 86604783

GI number: 86604783

Start: 49892

End: 51004

Strand: Reverse

Name: appC [H]

Synonym: CYA_0051

Alternate gene names: 86604783

Gene position: 51004-49892 (Counterclockwise)

Preceding gene: 86604785

Following gene: 86604781

Centisome position: 1.74

GC content: 62.71

Gene sequence:

>1113_bases
ATGCAGTGGTGGAAACGGCTTCGCCAAAATCGCTGGGCTCAAGCAGGAGCCTACATCCTCCTCGTTTTCTATACTTGCGC
CATTTTTGCCGAGTTTGTCGCCCCCTACAGCCCGCTGGAATCGCAGCCGGGGGGATCCCTTCTGCCCCCCACCGCCATTC
ACTTTTGGGACGAGTCGGGGGCTTGGCTGGGACCCCACGTTTATCCAACTCGCCAGGGGCCGGTGGATCTGGAAACGGGC
GAACGTCCGCTTTTGGTGGATACCAGCCGTCCCGCCGGGATCCGCCTGTTTGTGGCCGGCACCCCTTACCGTTGGTTGGG
TTTGATCCCCTGGGATCGACACCTATTCGGCACTGTCCCTCTGCGGACGGAGGAAGGGCTGCCCGTAGCGCGGCTACACC
TGCTGGGCACGGACGATCAAGGTCGCGACTACTTCAGCCGTCTGGTCTACGGTGGGCGCGTCAGCCTGTTCGTTGGCCTG
GTGGGCATCGGCATCTCTTTTCCCATCGGTCTGCTGGTGGGGGCCATATCCGGCTACTTCGGCGGCTGGGTGGATACGCT
GCTGATGCGGCTGACTGAGGTGTTGATGTCGATCCCGACGCTGTATTTGCTGGTGTCGTTGGCGGCGGTGTTGCAGGTGA
ACCCGCTGACCGGTGTGCCCTTCAGCAATGCCGAGCGCTTTTTGGTGATTGTGGCCATCCTCTCTTTGGTGGGTTGGGCG
GGCTTGGCCAGGGTGATTCGGGGGCAGGTGCTGTCCTTGCGGGAGCGAGACTTTGTGCAGGCGGCGCGGGTGGCCGGGGC
CGGATCCCTGTATCTGCTGGTGCGCCATATCCTGCCCCAGACCACCACCTACGTGGTGATCTCGGCAACCTTGGCGGTGC
CCGGCTATATCGTGGCAGAGTCGGTGCTGAGCTTGATCGGCCTGGGGATCCAACAGCCGGATGCCTCGTGGGGGAACATG
CTGTCGCTGGCCACCAACGCTTCGGTAATCATTCTGCAGCCCTGGCTGGTGCTGGCCCCCACCCTGATGGTGGTGCTCAC
CTCCCTGTCTTTTAACTTGCTGGGAGATGGCCTGCGAGATGCCCTCGACCCGCGGGATCCTGATCCTCGCTGA

Upstream 100 bases:

>100_bases
CTAGACTACAGAAATCAGGCCTTCTGGCTCTCTGGATTTGATTGGAAAATAAGCGCGGTATCGCTACCCTGAAAGCTCGC
CCAACCGGGATCCTGGCCTC

Downstream 100 bases:

>100_bases
GGAGAAGTTGCTTCCTGGTTTGCCGGCTGTAGAGGCAATGGGGCGGCCTGCCGTTCACCGTTTCCCGTCGGGATAGAGCC
GGTTGAGCCCCTTGCGAGCC

Product: oligopeptide ABC transporter, permease protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MQWWKRLRQNRWAQAGAYILLVFYTCAIFAEFVAPYSPLESQPGGSLLPPTAIHFWDESGAWLGPHVYPTRQGPVDLETG
ERPLLVDTSRPAGIRLFVAGTPYRWLGLIPWDRHLFGTVPLRTEEGLPVARLHLLGTDDQGRDYFSRLVYGGRVSLFVGL
VGIGISFPIGLLVGAISGYFGGWVDTLLMRLTEVLMSIPTLYLLVSLAAVLQVNPLTGVPFSNAERFLVIVAILSLVGWA
GLARVIRGQVLSLRERDFVQAARVAGAGSLYLLVRHILPQTTTYVVISATLAVPGYIVAESVLSLIGLGIQQPDASWGNM
LSLATNASVIILQPWLVLAPTLMVVLTSLSFNLLGDGLRDALDPRDPDPR

Sequences:

>Translated_370_residues
MQWWKRLRQNRWAQAGAYILLVFYTCAIFAEFVAPYSPLESQPGGSLLPPTAIHFWDESGAWLGPHVYPTRQGPVDLETG
ERPLLVDTSRPAGIRLFVAGTPYRWLGLIPWDRHLFGTVPLRTEEGLPVARLHLLGTDDQGRDYFSRLVYGGRVSLFVGL
VGIGISFPIGLLVGAISGYFGGWVDTLLMRLTEVLMSIPTLYLLVSLAAVLQVNPLTGVPFSNAERFLVIVAILSLVGWA
GLARVIRGQVLSLRERDFVQAARVAGAGSLYLLVRHILPQTTTYVVISATLAVPGYIVAESVLSLIGLGIQQPDASWGNM
LSLATNASVIILQPWLVLAPTLMVVLTSLSFNLLGDGLRDALDPRDPDPR
>Mature_370_residues
MQWWKRLRQNRWAQAGAYILLVFYTCAIFAEFVAPYSPLESQPGGSLLPPTAIHFWDESGAWLGPHVYPTRQGPVDLETG
ERPLLVDTSRPAGIRLFVAGTPYRWLGLIPWDRHLFGTVPLRTEEGLPVARLHLLGTDDQGRDYFSRLVYGGRVSLFVGL
VGIGISFPIGLLVGAISGYFGGWVDTLLMRLTEVLMSIPTLYLLVSLAAVLQVNPLTGVPFSNAERFLVIVAILSLVGWA
GLARVIRGQVLSLRERDFVQAARVAGAGSLYLLVRHILPQTTTYVVISATLAVPGYIVAESVLSLIGLGIQQPDASWGNM
LSLATNASVIILQPWLVLAPTLMVVLTSLSFNLLGDGLRDALDPRDPDPR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=234, Percent_Identity=42.7350427350427, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787054, Length=233, Percent_Identity=39.9141630901288, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787760, Length=243, Percent_Identity=38.6831275720165, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789964, Length=246, Percent_Identity=40.2439024390244, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789889, Length=233, Percent_Identity=37.3390557939914, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788505, Length=368, Percent_Identity=27.1739130434783, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787549, Length=229, Percent_Identity=32.3144104803493, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40418; Mature: 40418

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWWKRLRQNRWAQAGAYILLVFYTCAIFAEFVAPYSPLESQPGGSLLPPTAIHFWDESG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCC
AWLGPHVYPTRQGPVDLETGERPLLVDTSRPAGIRLFVAGTPYRWLGLIPWDRHLFGTVP
CEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCEEECCCCCCHHEECCC
LRTEEGLPVARLHLLGTDDQGRDYFSRLVYGGRVSLFVGLVGIGISFPIGLLVGAISGYF
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGWVDTLLMRLTEVLMSIPTLYLLVSLAAVLQVNPLTGVPFSNAERFLVIVAILSLVGWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GLARVIRGQVLSLRERDFVQAARVAGAGSLYLLVRHILPQTTTYVVISATLAVPGYIVAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEHHHCCHHHHHH
SVLSLIGLGIQQPDASWGNMLSLATNASVIILQPWLVLAPTLMVVLTSLSFNLLGDGLRD
HHHHHHCCCCCCCCCCHHCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHH
ALDPRDPDPR
HCCCCCCCCC
>Mature Secondary Structure
MQWWKRLRQNRWAQAGAYILLVFYTCAIFAEFVAPYSPLESQPGGSLLPPTAIHFWDESG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCC
AWLGPHVYPTRQGPVDLETGERPLLVDTSRPAGIRLFVAGTPYRWLGLIPWDRHLFGTVP
CEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCEEECCCCCCHHEECCC
LRTEEGLPVARLHLLGTDDQGRDYFSRLVYGGRVSLFVGLVGIGISFPIGLLVGAISGYF
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGWVDTLLMRLTEVLMSIPTLYLLVSLAAVLQVNPLTGVPFSNAERFLVIVAILSLVGWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GLARVIRGQVLSLRERDFVQAARVAGAGSLYLLVRHILPQTTTYVVISATLAVPGYIVAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEHHHCCHHHHHH
SVLSLIGLGIQQPDASWGNMLSLATNASVIILQPWLVLAPTLMVVLTSLSFNLLGDGLRD
HHHHHHCCCCCCCCCCHHCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHH
ALDPRDPDPR
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]