Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 86604763

GI number: 86604763

Start: 29715

End: 30161

Strand: Reverse

Name: fur [H]

Synonym: CYA_0030

Alternate gene names: 86604763

Gene position: 30161-29715 (Counterclockwise)

Preceding gene: 86604771

Following gene: 86604762

Centisome position: 1.03

GC content: 54.81

Gene sequence:

>447_bases
ATGGTCTACACGGAAGAAGCCTTCAAAGCGGAGCTAAATGCCAAAGGCTGGCGAGCCACTCGGCAGCGGGAAATCATCCT
CCAGACCTTTCAAAACTTGCCTGAGGGGACTCACCTGAGCGCCGAGGAGCTGCACAAAAAGCTGCGGGAAGAAGGCCACA
ACATCAGCCTTTCCACCATCTATCGCACCGTCAAGCTGATGGCGCGCATGGGCATTTTGCGCGAGCTGGAACTGACCGAA
GGCCACAAGCATTACGAGATCAACCAGCCGGCCCCCCACCACCACCACCATTTGGTGTGCATCAAGACCAACAAGGTCAT
TGAGTTCAAAAACAACGCCATCCTGAATATCAGCCAGAAGGTGGCTGAAAAGTACGGCTTTAAAGTGCTGGATTGCCAGC
TCACCATCATCGGCATCAGCCCGGAGGGACAGCGCTCGATCTTGTAG

Upstream 100 bases:

>100_bases
GCAGCCGAAAGTCAGTGGCGCTATCTTAAATGAGGCTATTATCAATTACAGAACTTATTGACTGTTACGGCGACGTTGCC
CAACAGCGGAGGGGGGCATC

Downstream 100 bases:

>100_bases
CCAAACAATTTCTGCAGCTCAGCTCCTGGATAAATGCTTGCCCTGGGCGTTCTGTACTGGGTTTGGGGGGAGATGGGGAT
CCCTTGGTAGAGAAAATGCC

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MVYTEEAFKAELNAKGWRATRQREIILQTFQNLPEGTHLSAEELHKKLREEGHNISLSTIYRTVKLMARMGILRELELTE
GHKHYEINQPAPHHHHHLVCIKTNKVIEFKNNAILNISQKVAEKYGFKVLDCQLTIIGISPEGQRSIL

Sequences:

>Translated_148_residues
MVYTEEAFKAELNAKGWRATRQREIILQTFQNLPEGTHLSAEELHKKLREEGHNISLSTIYRTVKLMARMGILRELELTE
GHKHYEINQPAPHHHHHLVCIKTNKVIEFKNNAILNISQKVAEKYGFKVLDCQLTIIGISPEGQRSIL
>Mature_148_residues
MVYTEEAFKAELNAKGWRATRQREIILQTFQNLPEGTHLSAEELHKKLREEGHNISLSTIYRTVKLMARMGILRELELTE
GHKHYEINQPAPHHHHHLVCIKTNKVIEFKNNAILNISQKVAEKYGFKVLDCQLTIIGISPEGQRSIL

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=33.8345864661654, Blast_Score=79, Evalue=9e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17102; Mature: 17102

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYTEEAFKAELNAKGWRATRQREIILQTFQNLPEGTHLSAEELHKKLREEGHNISLSTI
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEHHHH
YRTVKLMARMGILRELELTEGHKHYEINQPAPHHHHHLVCIKTNKVIEFKNNAILNISQK
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEECCCEEEECCCEEEEHHHH
VAEKYGFKVLDCQLTIIGISPEGQRSIL
HHHHHCCEEEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MVYTEEAFKAELNAKGWRATRQREIILQTFQNLPEGTHLSAEELHKKLREEGHNISLSTI
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEHHHH
YRTVKLMARMGILRELELTEGHKHYEINQPAPHHHHHLVCIKTNKVIEFKNNAILNISQK
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEECCCEEEECCCEEEEHHHH
VAEKYGFKVLDCQLTIIGISPEGQRSIL
HHHHHCCEEEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]