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The map label for this gene is htpX [H]

Identifier: 86604762

GI number: 86604762

Start: 27153

End: 29534

Strand: Reverse

Name: htpX [H]

Synonym: CYA_0029

Alternate gene names: 86604762

Gene position: 29534-27153 (Counterclockwise)

Preceding gene: 86604763

Following gene: 86604760

Centisome position: 1.01

GC content: 61.38

Gene sequence:

>2382_bases
ATGAACGAGCAGGAATTGGCGCAGTGGCTAGAGCAAGCTCTGGCAGACCTGCGTCTGAGAGTTCAGGTGAAGGCCCAGCC
CCTCCAAAGCAGTCCTGGGGATTACGCTTTGGTGATCATGATCAACCACCCTGCTCACGTTGCTCTCGACCATGAGAGGC
TGACGGCCTGGTTCCAGAAGGCAATTCCCAGCCGCTATCCCCAAGTCAAGCGCTTGGCTCTCTACAGCCGCCCCATCGGC
CAACAGCAGGCCAACTGGAAAACTCAGGTGAGGCTGGCTCCGGAAGCGGCGACGGGCAGGGGGGATCCCGCCGACAGTCC
AGATCTCAGCCGCTATTGCTTTGTCCAAGACCGCCAGTTGCTCACCGCTGACCTGCCTCAACCCTCCAGCGTGGTGCGCC
AGGCGGTCTTGGGTTTTCATAACCTCACCGCTGGGCAAAAGGAAGAAGTGCTGCCCCTGTTGCCCACCTTGTTCCGCAAC
CCCGGTGCTGTCTCGACGGCAATGCTGTCGGTGGATGCGGCCCTGTGGCTAGAGCCCTTGAAAAGCCTCAATCCCCACGA
GCTGCGCCTGTTGAGCGTTTGGCTGAGCCGCTATTGCTTCAACCCCAGCCGCGCCTTGGCCGACTTGGATCCCGCCACCT
CCAATCTCAGAACCGGTCAGACCCGACGCCGGTACCGCGCTCCTCAGACAGGGGTCTCGCTGGTTTTGGCCAGCTTTGCT
GGCAACCTCACTCTGGCCGCCGGCGTGACCCTGAGCCTGTTGTTCGGCATGGTGTTTGTGTTGGCCCTGGCCGTTTTCGG
CACCTTGGAAGGGGGGTTCTCTTTTGGCTCTTTTCTTTCCGCCGTTCTGCTCACCCTGGCCTTCAACGCCCTCATTTTCT
TTTTGTCTCCCTGGTTGATGGACTGGATCCAGCACAGCCTCTACAGCACCCAGTGGGTGAGCTTGGCGGAAATTGGGCGT
CGCAGCCCAGAGAGCGCGGAGGTGATCGCCCGCGTCTGTCGCCAGTACAAGCTGAAGCAGCCGAAGCTGGGCTTGATCCG
CGACCAAAACCCTACTGCTTTTACCTATGGCAGCCTGCCGGATACGGCCCGCATCGTCGTCAGCGAAGGGTTGTTCACCT
ACTTGGAAGATGAGGAGGTGGCCACGGTCTATGCCCACGAGCTGGGGCATGTGATCCACTGGGATTTTGCTGTCATGACC
CTGGCTTCCACGTTGGTGCAGATTCTCTACCTCCTCTACGTCTACCTGCGCGACACGCGCCGAGACCGCAGAGGGGGCAA
AAACATAGGTTCCTTGGCTCTGGTCGCCTACTTTTTCTACGTGGCCGGCTCCTACTTGGTGCTGTACCTGTCGCGGGTGC
GGGAGTACTTTGCCGATCACTTTGCCGCCGAAATCACCGGCAACCCCAATGCCCTCTCGCGGGCTCTGGTGAAAATAGCC
TTTGGCATTGTGCAAGAAGGGGAGCGGCAACAGGATGAGGAAACCCGACAGCGCAGCGCTCGCCTGCTGGAAGGCACACG
GGCCTTGGGGATCTACGATGCCAAGGCGGCGGTGATGGCGGGGACAGCCTACCGGGTGGCCGCGGATCCCAGCCAGGTGG
GCAGGGTGTTTTTGTGGGATCTGTTTAACCCTTGGGCCGGGTGGATGGAGCTGAACTCCACCCATCCCCTCACCGGCAAG
CGGGTGCGGGCGCTGGGCACCTATGCCGAACAACTGGATCTGCCGGTGGAGTTCGACATGGCCAGCGTGGTGGCCCAGGG
CAAGCAGCTCAACCGCCAGCAGCTCTACGGCAATTTTCTTCTGGACGTGGTTTTGTTAAACGCCGAGTGGCTGGGGGCGA
TCTTGGGGATGGTGCTTGGGATCCCCGCTCTGCAGGCGGGGTCTTACGGCATGTTTGCCGGCCTGGTTCTGGCGGGAGCC
AGCTTGGGCCTGCTGCTGAAGATGACGGTGATGTACCCCAGCTTGGAAAACCCGCCGGCATTGACGGTGTTGAAGGCCAT
GAGCAACCCCTACGCCAGCCCCTTGCGCGGCTTGCCGATGCAGCTAGAGGGGCGGGTGATCGGGCGGGGGGATGCGGGCT
ATCGCTTCGGCTCCGATCTCAAGTTCCAGGATGAGACGGGGATGATTTTCTTGCGCTATGTTTCTCGGTTTGGGCCGCTG
GGCAACTTCCTGTTTGGGGCCAGCCGGGCAGGCAGGCTGGTGGGTCAAGAAGGGACGGTGGTGGGATGGTTCCGGCGGGG
GATAGCTCCCTACCTGGATCTGTCCCGCTTCCAGAGCCGCTATGGCGAAGTGGTGACCAGCCATCCGGCCTTTGGACAGG
CGGTGCAGGTGGCGCTGGGCTTGATGGCCGCCTTGCTGCTGATGACCGTTTTCCCCTTCTAG

Upstream 100 bases:

>100_bases
CCCTTGGTAGAGAAAATGCCAGAATAGCCGCTGTAAAGTCGAAAGCCATTGGCAATTGAAGCAATAGCTCAGCTTACCCT
ACCCCCTCCGGGAGACGGCC

Downstream 100 bases:

>100_bases
GACGGGCTCAGGATGAGGTCGACTGCCCGCTGTCGGCGCGGGCGTAGTCGTCGCTGAAGCGGATAATGTCGTCTTCGCCC
AGGTACTGGCCGTTTTGCAC

Product: M48B family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MNEQELAQWLEQALADLRLRVQVKAQPLQSSPGDYALVIMINHPAHVALDHERLTAWFQKAIPSRYPQVKRLALYSRPIG
QQQANWKTQVRLAPEAATGRGDPADSPDLSRYCFVQDRQLLTADLPQPSSVVRQAVLGFHNLTAGQKEEVLPLLPTLFRN
PGAVSTAMLSVDAALWLEPLKSLNPHELRLLSVWLSRYCFNPSRALADLDPATSNLRTGQTRRRYRAPQTGVSLVLASFA
GNLTLAAGVTLSLLFGMVFVLALAVFGTLEGGFSFGSFLSAVLLTLAFNALIFFLSPWLMDWIQHSLYSTQWVSLAEIGR
RSPESAEVIARVCRQYKLKQPKLGLIRDQNPTAFTYGSLPDTARIVVSEGLFTYLEDEEVATVYAHELGHVIHWDFAVMT
LASTLVQILYLLYVYLRDTRRDRRGGKNIGSLALVAYFFYVAGSYLVLYLSRVREYFADHFAAEITGNPNALSRALVKIA
FGIVQEGERQQDEETRQRSARLLEGTRALGIYDAKAAVMAGTAYRVAADPSQVGRVFLWDLFNPWAGWMELNSTHPLTGK
RVRALGTYAEQLDLPVEFDMASVVAQGKQLNRQQLYGNFLLDVVLLNAEWLGAILGMVLGIPALQAGSYGMFAGLVLAGA
SLGLLLKMTVMYPSLENPPALTVLKAMSNPYASPLRGLPMQLEGRVIGRGDAGYRFGSDLKFQDETGMIFLRYVSRFGPL
GNFLFGASRAGRLVGQEGTVVGWFRRGIAPYLDLSRFQSRYGEVVTSHPAFGQAVQVALGLMAALLLMTVFPF

Sequences:

>Translated_793_residues
MNEQELAQWLEQALADLRLRVQVKAQPLQSSPGDYALVIMINHPAHVALDHERLTAWFQKAIPSRYPQVKRLALYSRPIG
QQQANWKTQVRLAPEAATGRGDPADSPDLSRYCFVQDRQLLTADLPQPSSVVRQAVLGFHNLTAGQKEEVLPLLPTLFRN
PGAVSTAMLSVDAALWLEPLKSLNPHELRLLSVWLSRYCFNPSRALADLDPATSNLRTGQTRRRYRAPQTGVSLVLASFA
GNLTLAAGVTLSLLFGMVFVLALAVFGTLEGGFSFGSFLSAVLLTLAFNALIFFLSPWLMDWIQHSLYSTQWVSLAEIGR
RSPESAEVIARVCRQYKLKQPKLGLIRDQNPTAFTYGSLPDTARIVVSEGLFTYLEDEEVATVYAHELGHVIHWDFAVMT
LASTLVQILYLLYVYLRDTRRDRRGGKNIGSLALVAYFFYVAGSYLVLYLSRVREYFADHFAAEITGNPNALSRALVKIA
FGIVQEGERQQDEETRQRSARLLEGTRALGIYDAKAAVMAGTAYRVAADPSQVGRVFLWDLFNPWAGWMELNSTHPLTGK
RVRALGTYAEQLDLPVEFDMASVVAQGKQLNRQQLYGNFLLDVVLLNAEWLGAILGMVLGIPALQAGSYGMFAGLVLAGA
SLGLLLKMTVMYPSLENPPALTVLKAMSNPYASPLRGLPMQLEGRVIGRGDAGYRFGSDLKFQDETGMIFLRYVSRFGPL
GNFLFGASRAGRLVGQEGTVVGWFRRGIAPYLDLSRFQSRYGEVVTSHPAFGQAVQVALGLMAALLLMTVFPF
>Mature_793_residues
MNEQELAQWLEQALADLRLRVQVKAQPLQSSPGDYALVIMINHPAHVALDHERLTAWFQKAIPSRYPQVKRLALYSRPIG
QQQANWKTQVRLAPEAATGRGDPADSPDLSRYCFVQDRQLLTADLPQPSSVVRQAVLGFHNLTAGQKEEVLPLLPTLFRN
PGAVSTAMLSVDAALWLEPLKSLNPHELRLLSVWLSRYCFNPSRALADLDPATSNLRTGQTRRRYRAPQTGVSLVLASFA
GNLTLAAGVTLSLLFGMVFVLALAVFGTLEGGFSFGSFLSAVLLTLAFNALIFFLSPWLMDWIQHSLYSTQWVSLAEIGR
RSPESAEVIARVCRQYKLKQPKLGLIRDQNPTAFTYGSLPDTARIVVSEGLFTYLEDEEVATVYAHELGHVIHWDFAVMT
LASTLVQILYLLYVYLRDTRRDRRGGKNIGSLALVAYFFYVAGSYLVLYLSRVREYFADHFAAEITGNPNALSRALVKIA
FGIVQEGERQQDEETRQRSARLLEGTRALGIYDAKAAVMAGTAYRVAADPSQVGRVFLWDLFNPWAGWMELNSTHPLTGK
RVRALGTYAEQLDLPVEFDMASVVAQGKQLNRQQLYGNFLLDVVLLNAEWLGAILGMVLGIPALQAGSYGMFAGLVLAGA
SLGLLLKMTVMYPSLENPPALTVLKAMSNPYASPLRGLPMQLEGRVIGRGDAGYRFGSDLKFQDETGMIFLRYVSRFGPL
GNFLFGASRAGRLVGQEGTVVGWFRRGIAPYLDLSRFQSRYGEVVTSHPAFGQAVQVALGLMAALLLMTVFPF

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 87713; Mature: 87713

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQELAQWLEQALADLRLRVQVKAQPLQSSPGDYALVIMINHPAHVALDHERLTAWFQK
CCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECHHHHHHHHHH
AIPSRYPQVKRLALYSRPIGQQQANWKTQVRLAPEAATGRGDPADSPDLSRYCFVQDRQL
HCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHH
LTADLPQPSSVVRQAVLGFHNLTAGQKEEVLPLLPTLFRNPGAVSTAMLSVDAALWLEPL
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KSLNPHELRLLSVWLSRYCFNPSRALADLDPATSNLRTGQTRRRYRAPQTGVSLVLASFA
HCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHC
GNLTLAAGVTLSLLFGMVFVLALAVFGTLEGGFSFGSFLSAVLLTLAFNALIFFLSPWLM
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DWIQHSLYSTQWVSLAEIGRRSPESAEVIARVCRQYKLKQPKLGLIRDQNPTAFTYGSLP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCCC
DTARIVVSEGLFTYLEDEEVATVYAHELGHVIHWDFAVMTLASTLVQILYLLYVYLRDTR
CHHHHEECCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDRRGGKNIGSLALVAYFFYVAGSYLVLYLSRVREYFADHFAAEITGNPNALSRALVKIA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
FGIVQEGERQQDEETRQRSARLLEGTRALGIYDAKAAVMAGTAYRVAADPSQVGRVFLWD
HHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEECCHHHHHCCCEEEEECCHHHHCHHHHHH
LFNPWAGWMELNSTHPLTGKRVRALGTYAEQLDLPVEFDMASVVAQGKQLNRQQLYGNFL
HHCCHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDVVLLNAEWLGAILGMVLGIPALQAGSYGMFAGLVLAGASLGLLLKMTVMYPSLENPPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LTVLKAMSNPYASPLRGLPMQLEGRVIGRGDAGYRFGSDLKFQDETGMIFLRYVSRFGPL
HHHHHHHCCCCCCHHCCCCCEECCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCH
GNFLFGASRAGRLVGQEGTVVGWFRRGIAPYLDLSRFQSRYGEVVTSHPAFGQAVQVALG
HHHHHCCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHH
LMAALLLMTVFPF
HHHHHHHHHHCCC
>Mature Secondary Structure
MNEQELAQWLEQALADLRLRVQVKAQPLQSSPGDYALVIMINHPAHVALDHERLTAWFQK
CCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECHHHHHHHHHH
AIPSRYPQVKRLALYSRPIGQQQANWKTQVRLAPEAATGRGDPADSPDLSRYCFVQDRQL
HCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHH
LTADLPQPSSVVRQAVLGFHNLTAGQKEEVLPLLPTLFRNPGAVSTAMLSVDAALWLEPL
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KSLNPHELRLLSVWLSRYCFNPSRALADLDPATSNLRTGQTRRRYRAPQTGVSLVLASFA
HCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHC
GNLTLAAGVTLSLLFGMVFVLALAVFGTLEGGFSFGSFLSAVLLTLAFNALIFFLSPWLM
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DWIQHSLYSTQWVSLAEIGRRSPESAEVIARVCRQYKLKQPKLGLIRDQNPTAFTYGSLP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCCC
DTARIVVSEGLFTYLEDEEVATVYAHELGHVIHWDFAVMTLASTLVQILYLLYVYLRDTR
CHHHHEECCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDRRGGKNIGSLALVAYFFYVAGSYLVLYLSRVREYFADHFAAEITGNPNALSRALVKIA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
FGIVQEGERQQDEETRQRSARLLEGTRALGIYDAKAAVMAGTAYRVAADPSQVGRVFLWD
HHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEECCHHHHHCCCEEEEECCHHHHCHHHHHH
LFNPWAGWMELNSTHPLTGKRVRALGTYAEQLDLPVEFDMASVVAQGKQLNRQQLYGNFL
HHCCHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDVVLLNAEWLGAILGMVLGIPALQAGSYGMFAGLVLAGASLGLLLKMTVMYPSLENPPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LTVLKAMSNPYASPLRGLPMQLEGRVIGRGDAGYRFGSDLKFQDETGMIFLRYVSRFGPL
HHHHHHHCCCCCCHHCCCCCEECCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCH
GNFLFGASRAGRLVGQEGTVVGWFRRGIAPYLDLSRFQSRYGEVVTSHPAFGQAVQVALG
HHHHHCCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHH
LMAALLLMTVFPF
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]