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The map label for this gene is vbsD

Identifier: 86361190

GI number: 86361190

Start: 519260

End: 520678

Strand: Direct

Name: vbsD

Synonym: RHE_PF00460

Alternate gene names: 86361190

Gene position: 519260-520678 (Clockwise)

Preceding gene: 86361189

Following gene: 86361191

Centisome position: 80.82

GC content: 65.12

Gene sequence:

>1419_bases
ATGAACGACATGAGCGAGATGAGCGGCAGCCTGCGGAAAGGGCGGCTTGCGCCGGAAGATCTTGCCAGCCCGCACCTTTT
CAGGCTGCTGCTGCGGCTCGGGCTGCCCGCCATGTTCGGCCTGTCGATCAACGCCGCCCACCACACGATCAACATGATCT
TCGTCGGCATGATCGGCGAAGACCAGATCGCCGCGATCATGATCGTGCTGCCGGTCCTGATGCTCGTCGCCGCTTTCGGC
GAAGGCATCGGCGTCGGTGTGGCGACCGAGGTCGGGCGCGCACTCGGCGCCGGCAACCGGTCGAGAGCCAGCACCCTTGC
CTCGGTCAGCCTTGCCGCCGGCGTCGCCTTCGGCGCCGCAAGCGCGGTTGCGATCGCAGCCTTTCCCTCGGTTCTGCTGT
TCGGCGCCACATCAGCGATCGAGCCGCTGGCACAGCATTATCTCCTCGTCATCGTGGTCTCGATTCCACTGACGATGGCG
CAGATCATTCTCGACTTTCTGGCAATAGCCGAGGGCAATGCCCGCTTCAGCATGTGGACGCTCGTCGCCTGCTTCGCGCT
GAACATCATCCTCGACCCGATCATGATCTTTGGCTTCGGTCTCGGCCTGCAGGGCGCGGCGATGGCAACCATCCTCTCCC
AGCTCGTGGCGCTCTCGATCTACGGCGCCTATCATGCGAGGCGGCTTGGGACGATCCGACTGACGTTCGGCTGGCCATTC
GGCGACCTCAGGCATCTCAAGGCGGTCCTTGCTGTGGGCGCACCGACGACGCTGACGAGCCTCGCGACGGCGGGCGCAAT
CGCTGCGATGCTGTCGGTCGCCGGCACCTATCACGGTGAAGACGGCATCGCCGGCGTCGGCATCGCCTTGCGGCTGCTTG
CGGTCGGCGCTTTGCCGGTCATCGGCATTTCGCTCGGGGCGCAGTCCATCCTGAGCTTTGCCTGGGGGCGCGGGGATATC
TCCCGGGTGCTGGCGGCAGCCCGCATGCTCTCAGTTGTCACGAGCGCGGTCGGCGGCGTCTACGGGCTGGCAGCGATCAT
CTTTTCCGAGCGTCTTGCCGCGTTTTTCACCGACGAAGCTTCCGTGCTTTCGATCGCCGGCCAGGCGATCGTCGCAACCC
ATCTTCCCTTCCTGCTGTTCGGCCTCCGGCAGACCGTGCTGATCCTCTTCCAGGCGCAGGGCAGGCCGAACGCCGCCCTT
GCCGTCGGCCTGGCGCAGAACGGATATCTTCTCTTTCCGCTGCTTGCGCTGCTGCCGCCCTTCTTCGGATTCTCCGGCCT
GCTCTGGGCCATGTTCCTGGCTTCGGCGCTCACTGGCCTGTTGTCATGCTTCTGCCTCGCCCGATCCCTCGGCGCGCTCC
GGCAGCGCTCGGACGAACCTCTGACATCAATCCGTCCCTATCCCCGCTTTTGTCCATGA

Upstream 100 bases:

>100_bases
TCGCCAAGGTCAAGCATTTCGATTTTCCGCATAAGCGGGCGCTGCTCGTGATGCTGAGCCGCGAGCGTTTCTTCGGCGAT
CATCTCTGGGTGCCGGCATC

Downstream 100 bases:

>100_bases
GAGGATTATCATGAACCAGTCCTTCAGCCCCCGCGACCTTGGCGCCCATGCGGCCGCCGACGATCTCTTCACCCCCGTCC
ATCCGGCCGCCTTCAACGCC

Product: efflux transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MNDMSEMSGSLRKGRLAPEDLASPHLFRLLLRLGLPAMFGLSINAAHHTINMIFVGMIGEDQIAAIMIVLPVLMLVAAFG
EGIGVGVATEVGRALGAGNRSRASTLASVSLAAGVAFGAASAVAIAAFPSVLLFGATSAIEPLAQHYLLVIVVSIPLTMA
QIILDFLAIAEGNARFSMWTLVACFALNIILDPIMIFGFGLGLQGAAMATILSQLVALSIYGAYHARRLGTIRLTFGWPF
GDLRHLKAVLAVGAPTTLTSLATAGAIAAMLSVAGTYHGEDGIAGVGIALRLLAVGALPVIGISLGAQSILSFAWGRGDI
SRVLAAARMLSVVTSAVGGVYGLAAIIFSERLAAFFTDEASVLSIAGQAIVATHLPFLLFGLRQTVLILFQAQGRPNAAL
AVGLAQNGYLLFPLLALLPPFFGFSGLLWAMFLASALTGLLSCFCLARSLGALRQRSDEPLTSIRPYPRFCP

Sequences:

>Translated_472_residues
MNDMSEMSGSLRKGRLAPEDLASPHLFRLLLRLGLPAMFGLSINAAHHTINMIFVGMIGEDQIAAIMIVLPVLMLVAAFG
EGIGVGVATEVGRALGAGNRSRASTLASVSLAAGVAFGAASAVAIAAFPSVLLFGATSAIEPLAQHYLLVIVVSIPLTMA
QIILDFLAIAEGNARFSMWTLVACFALNIILDPIMIFGFGLGLQGAAMATILSQLVALSIYGAYHARRLGTIRLTFGWPF
GDLRHLKAVLAVGAPTTLTSLATAGAIAAMLSVAGTYHGEDGIAGVGIALRLLAVGALPVIGISLGAQSILSFAWGRGDI
SRVLAAARMLSVVTSAVGGVYGLAAIIFSERLAAFFTDEASVLSIAGQAIVATHLPFLLFGLRQTVLILFQAQGRPNAAL
AVGLAQNGYLLFPLLALLPPFFGFSGLLWAMFLASALTGLLSCFCLARSLGALRQRSDEPLTSIRPYPRFCP
>Mature_472_residues
MNDMSEMSGSLRKGRLAPEDLASPHLFRLLLRLGLPAMFGLSINAAHHTINMIFVGMIGEDQIAAIMIVLPVLMLVAAFG
EGIGVGVATEVGRALGAGNRSRASTLASVSLAAGVAFGAASAVAIAAFPSVLLFGATSAIEPLAQHYLLVIVVSIPLTMA
QIILDFLAIAEGNARFSMWTLVACFALNIILDPIMIFGFGLGLQGAAMATILSQLVALSIYGAYHARRLGTIRLTFGWPF
GDLRHLKAVLAVGAPTTLTSLATAGAIAAMLSVAGTYHGEDGIAGVGIALRLLAVGALPVIGISLGAQSILSFAWGRGDI
SRVLAAARMLSVVTSAVGGVYGLAAIIFSERLAAFFTDEASVLSIAGQAIVATHLPFLLFGLRQTVLILFQAQGRPNAAL
AVGLAQNGYLLFPLLALLPPFFGFSGLLWAMFLASALTGLLSCFCLARSLGALRQRSDEPLTSIRPYPRFCP

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49087; Mature: 49087

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMSEMSGSLRKGRLAPEDLASPHLFRLLLRLGLPAMFGLSINAAHHTINMIFVGMIGE
CCCHHHHHCHHHCCCCCCHHHCCHHHHHHHHHHCCCHHHCCEEHHHHHEEEEEEEEECCC
DQIAAIMIVLPVLMLVAAFGEGIGVGVATEVGRALGAGNRSRASTLASVSLAAGVAFGAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SAVAIAAFPSVLLFGATSAIEPLAQHYLLVIVVSIPLTMAQIILDFLAIAEGNARFSMWT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LVACFALNIILDPIMIFGFGLGLQGAAMATILSQLVALSIYGAYHARRLGTIRLTFGWPF
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GDLRHLKAVLAVGAPTTLTSLATAGAIAAMLSVAGTYHGEDGIAGVGIALRLLAVGALPV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IGISLGAQSILSFAWGRGDISRVLAAARMLSVVTSAVGGVYGLAAIIFSERLAAFFTDEA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLSIAGQAIVATHLPFLLFGLRQTVLILFQAQGRPNAALAVGLAQNGYLLFPLLALLPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCCHHHHHHHHHHH
FFGFSGLLWAMFLASALTGLLSCFCLARSLGALRQRSDEPLTSIRPYPRFCP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MNDMSEMSGSLRKGRLAPEDLASPHLFRLLLRLGLPAMFGLSINAAHHTINMIFVGMIGE
CCCHHHHHCHHHCCCCCCHHHCCHHHHHHHHHHCCCHHHCCEEHHHHHEEEEEEEEECCC
DQIAAIMIVLPVLMLVAAFGEGIGVGVATEVGRALGAGNRSRASTLASVSLAAGVAFGAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SAVAIAAFPSVLLFGATSAIEPLAQHYLLVIVVSIPLTMAQIILDFLAIAEGNARFSMWT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LVACFALNIILDPIMIFGFGLGLQGAAMATILSQLVALSIYGAYHARRLGTIRLTFGWPF
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GDLRHLKAVLAVGAPTTLTSLATAGAIAAMLSVAGTYHGEDGIAGVGIALRLLAVGALPV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IGISLGAQSILSFAWGRGDISRVLAAARMLSVVTSAVGGVYGLAAIIFSERLAAFFTDEA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLSIAGQAIVATHLPFLLFGLRQTVLILFQAQGRPNAALAVGLAQNGYLLFPLLALLPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCCHHHHHHHHHHH
FFGFSGLLWAMFLASALTGLLSCFCLARSLGALRQRSDEPLTSIRPYPRFCP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA