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The map label for this gene is ygjG [C]

Identifier: 86361164

GI number: 86361164

Start: 486351

End: 487685

Strand: Direct

Name: ygjG [C]

Synonym: RHE_PF00434

Alternate gene names: 86361164

Gene position: 486351-487685 (Clockwise)

Preceding gene: 86361162

Following gene: 86361168

Centisome position: 75.69

GC content: 63.75

Gene sequence:

>1335_bases
ATGGACCAGATCAGCAAGACGAATGCGCCCGTACTCGAAAATTTCTGGATGCCGTTCACCGCCAACCGGCAATTCAAGGC
CGCGCCGCGCCTGCTGGCCGCTGCCGAAGGGATGTATTACACCGACGTCGATGGAAACCGGGTGCTGGACGGCACGGCCG
GGCTCTGGTGCTGCAACGCCGGCCACGGCCGCAGGAAGATCGCCCAGGCGGTCGAGCGGCAGCTTGCCACGCTCGACTAT
GCGCCGACCTTCCAGATGGGGCATCCGATCGCCTTCGACTTCGCCGCCAAGCTCGCTGCGAACGCACCGGGCGGCGCTAA
CGCCAAGCTCGACAGGGTCTTCTTCACCGGCTCGGGCTCGGAATCGGTCGACACGGCTCTGAAGATCGCCATCGCCTACC
AGCGCGCCATCGGCCAGGGCACCCGCACTCGGATCATCGGCCGTGAAAAAGGCTATCACGGCGTCGGCTTCGGCGGCATT
TCCGTCGGTGGCCTCGTCAACAATCGGCGGGTCTTCCCGCAGATCCCGGCCGATCACATGCGCCATACGCTGGATATCGG
GCGCAATGCCTTTTCAAAGGGGCTTCCCACGCATGGCGTCGAACTGGCCGACGATCTCGAACGCCTGGTGCAGTTGCACG
GCGCCGAAACCATCGCCGCTGTCATCGTCGAGCCGATGTCGGGATCGGCGGGTGTTGTCCTGCCGCCGAAGGGATATCTG
GAAAGGCTGCGCGCGACCGCCGACAAGTACGGCATCCTGCTGATTTTTGACGAAGTCATCACCGGCTTCGGTCGTCTCGG
CACACCTTTCGCGGTCGACTATTTCGGCGTCGTTCCCGATCTGGTCACCACGGCGAAGGGCCTGACGAACGGCGCCGTAC
CCATGGGCGCGGTCTTTGCCAGCCGTAAGGTCCATGACGGACTTATGGTCGGACCCGATACTGCGATCGAACTCTTCCAC
GGCTACACCTATTCCGGCCATCCGGTCGCTTGCGCCGCAGGGCTCGCCACCCTCGAAATCTACGAGGAAGAAGGGCTGCT
GACGCGTGCATCCGACCTGGCCGAATATTGGCAGGACGCCCTGCACTCATTGAAGGGCCTCGCGCACGTCGTTGACATCC
GCAATCTCGGCCTGGTCGGCGCGATCGAACTGGCGCCGCGTGACGGTGCTGCCGGAAAGCGCGCCTACGATGTCTTCGTC
GACTGCTTCAACAAGGGGCTGCTGATCCGCGTGACCGGCGACATCATCGCTCTGTCTCCACCGCTGATCATCGAGAAGGA
GCAGATCGACACGCTCGTCTCGACGCTTGGGGAGGCCCTGAAACGCGCGGCCTAG

Upstream 100 bases:

>100_bases
TTCTTCATTGTTCAATTTCAATAACTTGCATCACCGAAGAAAAGGACTTGTTTGAAAGATTGAAATTGCCATTCTCCAGG
CGATTTCAAAGGAGGCCAGG

Downstream 100 bases:

>100_bases
AGCATTTGCCGTCGGCGATCGGACGCTCGGTCCGTCGCCGATGGAACCGTCTGGGACGCCGAGGCGGAGTTCAGCGCTTC
AGCGTCTGCGACGGCAGCTC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MDQISKTNAPVLENFWMPFTANRQFKAAPRLLAAAEGMYYTDVDGNRVLDGTAGLWCCNAGHGRRKIAQAVERQLATLDY
APTFQMGHPIAFDFAAKLAANAPGGANAKLDRVFFTGSGSESVDTALKIAIAYQRAIGQGTRTRIIGREKGYHGVGFGGI
SVGGLVNNRRVFPQIPADHMRHTLDIGRNAFSKGLPTHGVELADDLERLVQLHGAETIAAVIVEPMSGSAGVVLPPKGYL
ERLRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAVPMGAVFASRKVHDGLMVGPDTAIELFH
GYTYSGHPVACAAGLATLEIYEEEGLLTRASDLAEYWQDALHSLKGLAHVVDIRNLGLVGAIELAPRDGAAGKRAYDVFV
DCFNKGLLIRVTGDIIALSPPLIIEKEQIDTLVSTLGEALKRAA

Sequences:

>Translated_444_residues
MDQISKTNAPVLENFWMPFTANRQFKAAPRLLAAAEGMYYTDVDGNRVLDGTAGLWCCNAGHGRRKIAQAVERQLATLDY
APTFQMGHPIAFDFAAKLAANAPGGANAKLDRVFFTGSGSESVDTALKIAIAYQRAIGQGTRTRIIGREKGYHGVGFGGI
SVGGLVNNRRVFPQIPADHMRHTLDIGRNAFSKGLPTHGVELADDLERLVQLHGAETIAAVIVEPMSGSAGVVLPPKGYL
ERLRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAVPMGAVFASRKVHDGLMVGPDTAIELFH
GYTYSGHPVACAAGLATLEIYEEEGLLTRASDLAEYWQDALHSLKGLAHVVDIRNLGLVGAIELAPRDGAAGKRAYDVFV
DCFNKGLLIRVTGDIIALSPPLIIEKEQIDTLVSTLGEALKRAA
>Mature_444_residues
MDQISKTNAPVLENFWMPFTANRQFKAAPRLLAAAEGMYYTDVDGNRVLDGTAGLWCCNAGHGRRKIAQAVERQLATLDY
APTFQMGHPIAFDFAAKLAANAPGGANAKLDRVFFTGSGSESVDTALKIAIAYQRAIGQGTRTRIIGREKGYHGVGFGGI
SVGGLVNNRRVFPQIPADHMRHTLDIGRNAFSKGLPTHGVELADDLERLVQLHGAETIAAVIVEPMSGSAGVVLPPKGYL
ERLRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAVPMGAVFASRKVHDGLMVGPDTAIELFH
GYTYSGHPVACAAGLATLEIYEEEGLLTRASDLAEYWQDALHSLKGLAHVVDIRNLGLVGAIELAPRDGAAGKRAYDVFV
DCFNKGLLIRVTGDIIALSPPLIIEKEQIDTLVSTLGEALKRAA

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=28.9592760180996, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=26.6666666666667, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI226442705, Length=435, Percent_Identity=26.8965517241379, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4557809, Length=425, Percent_Identity=26.5882352941176, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442709, Length=399, Percent_Identity=27.0676691729323, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI284507298, Length=256, Percent_Identity=32.03125, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI24119277, Length=453, Percent_Identity=26.0485651214128, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI145693181, Length=409, Percent_Identity=32.518337408313, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786991, Length=439, Percent_Identity=30.751708428246, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=30, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787560, Length=441, Percent_Identity=29.7052154195011, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788044, Length=428, Percent_Identity=28.7383177570093, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789759, Length=444, Percent_Identity=26.8018018018018, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786349, Length=346, Percent_Identity=30.0578034682081, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32564660, Length=442, Percent_Identity=30.7692307692308, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25144271, Length=432, Percent_Identity=28.4722222222222, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=441, Percent_Identity=27.2108843537415, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=235, Percent_Identity=35.3191489361702, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323470, Length=437, Percent_Identity=28.1464530892449, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=481, Percent_Identity=26.1954261954262, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=26.9607843137255, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI161085790, Length=442, Percent_Identity=28.9592760180996, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357415, Length=420, Percent_Identity=29.0476190476191, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=28.5393258426966, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21356575, Length=454, Percent_Identity=27.5330396475771, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 47439; Mature: 47439

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQISKTNAPVLENFWMPFTANRQFKAAPRLLAAAEGMYYTDVDGNRVLDGTAGLWCCNA
CCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEECC
GHGRRKIAQAVERQLATLDYAPTFQMGHPIAFDFAAKLAANAPGGANAKLDRVFFTGSGS
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCC
ESVDTALKIAIAYQRAIGQGTRTRIIGREKGYHGVGFGGISVGGLVNNRRVFPQIPADHM
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCEECCCEECCCCCHHHH
RHTLDIGRNAFSKGLPTHGVELADDLERLVQLHGAETIAAVIVEPMSGSAGVVLPPKGYL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEECCHHHH
ERLRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAVPMGAVFA
HHHHHHHHHCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SRKVHDGLMVGPDTAIELFHGYTYSGHPVACAAGLATLEIYEEEGLLTRASDLAEYWQDA
HHHHCCCEEECCCHHHHHHHCCCCCCCCHHHHHCHHEEEEECCCCCHHHHHHHHHHHHHH
LHSLKGLAHVVDIRNLGLVGAIELAPRDGAAGKRAYDVFVDCFNKGLLIRVTGDIIALSP
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEECC
PLIIEKEQIDTLVSTLGEALKRAA
CCEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQISKTNAPVLENFWMPFTANRQFKAAPRLLAAAEGMYYTDVDGNRVLDGTAGLWCCNA
CCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEECC
GHGRRKIAQAVERQLATLDYAPTFQMGHPIAFDFAAKLAANAPGGANAKLDRVFFTGSGS
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCC
ESVDTALKIAIAYQRAIGQGTRTRIIGREKGYHGVGFGGISVGGLVNNRRVFPQIPADHM
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCEECCCEECCCCCHHHH
RHTLDIGRNAFSKGLPTHGVELADDLERLVQLHGAETIAAVIVEPMSGSAGVVLPPKGYL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEECCHHHH
ERLRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAVPMGAVFA
HHHHHHHHHCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SRKVHDGLMVGPDTAIELFHGYTYSGHPVACAAGLATLEIYEEEGLLTRASDLAEYWQDA
HHHHCCCEEECCCHHHHHHHCCCCCCCCHHHHHCHHEEEEECCCCCHHHHHHHHHHHHHH
LHSLKGLAHVVDIRNLGLVGAIELAPRDGAAGKRAYDVFVDCFNKGLLIRVTGDIIALSP
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEECC
PLIIEKEQIDTLVSTLGEALKRAA
CCEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]