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The map label for this gene is hcr [H]

Identifier: 86361119

GI number: 86361119

Start: 441338

End: 442429

Strand: Direct

Name: hcr [H]

Synonym: RHE_PF00389

Alternate gene names: 86361119

Gene position: 441338-442429 (Clockwise)

Preceding gene: 86361118

Following gene: 86361138

Centisome position: 68.69

GC content: 64.19

Gene sequence:

>1092_bases
ATGGATACTAGGAACCCGCAAGCGCCGCTCGCAAAGGCAACCCGTCACGACGTCTGGAATCCCGAGGAAGACGATACACT
CGTCTGCCTCGACGTGCAGCAGGAGACCCATGACGTCAAGACCTTCACCTTCGCCTCTCGTGACGGCAAGCGTTTCGCCT
TCAAGGCCGGCCAGTATTTCCTGTTCGACCTCGAGCACAACGGCGAGCCCGAGAGCCGGTGCTACAGCATCTCCTCTTCG
CCGCACCGCACGAACGCCTTCTCGGTGACGGTGAAGCGCGTTCCCGGCGGCAAGATCTCCAACTGGCTTCACGAGACGCT
GGTGCCGGGGGCATCGGTCAAGGCGAACGGCCCGCTCGGCCATTTCGTCCGGTCCGAGGCGGTAAAGCCGAAGCTTCTGC
TGCTCTCCGGCGGCTCCGGCATCACGCCCGTCATGTCCATTCTGCGTGAACTCGCCGACAGCTGCGCGCCGGCCGACGTC
GTCTTCATGCATGCGGCGCGTACCCCGCTCGATCTGATCTTCCGCGACGAACTCGCCTGCATCGCCCGCAGGCTGAAAGG
GCTGCGGCTGCATTTCCTGCCGGAAACGGTTGCGGGCGAGCCCTCCTGGTCCGGCCTTACCGGCCGCATTTCGGCGGATT
ATTTCAGGCTGGCGGTTCCCGATATCGCAGACCGCACGGTGATGTGCTGCGGCCCCGCCCCCTTCATGGCGGCAGCGCGC
GGCATTGCCGCCAAACTCGGCGTTCCCGCCGCGCATTATCTCGAGGAAAGCTTCGACGCCGCCGTCATCGACGAACCGGA
GATCCCCGCGATCCAGGAAGCCGCCGCCAAGGTCTTTCGGGTCACCTTCTCCAAACAGGCCCGCAGCATCGAGGTAACAG
GCGATCAGAGCGTGCTCTCCTGCGCGAAGAAGTCGGGCGTCAGGATTCCGTCCTCCTGCGCCAACGGCGTCTGCGGCACC
TGCAAGTCGAAGCTCACATCAGGCACGGTCGACATGAACCACAATGGCGGCATCCGCCAGCGGGAAATCGACGCCGGCTT
CTTCCTGCCTTGCTGCTCGAAGCCGCTCAGCGATCTCGTCATCGAACGCTGA

Upstream 100 bases:

>100_bases
GGCGCTCTCGATCCGGCTTATCAGCCAGGCCCCTATTCCCGCTTCTCCGAGACGAACCTCGACAAGTTCGCCACCTGGTA
CATCGACCGGATGCGCGCTC

Downstream 100 bases:

>100_bases
GCGACACCGCATCAATCACCGGGGGATCACCCGGATGCTACGAGACGAAAATGAGTCCGTCGAGCTGAGCGGCTCTTTCT
GGGAGAGGTCTGAGACGTCG

Product: putative ferredoxin oxidoreductase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDTRNPQAPLAKATRHDVWNPEEDDTLVCLDVQQETHDVKTFTFASRDGKRFAFKAGQYFLFDLEHNGEPESRCYSISSS
PHRTNAFSVTVKRVPGGKISNWLHETLVPGASVKANGPLGHFVRSEAVKPKLLLLSGGSGITPVMSILRELADSCAPADV
VFMHAARTPLDLIFRDELACIARRLKGLRLHFLPETVAGEPSWSGLTGRISADYFRLAVPDIADRTVMCCGPAPFMAAAR
GIAAKLGVPAAHYLEESFDAAVIDEPEIPAIQEAAAKVFRVTFSKQARSIEVTGDQSVLSCAKKSGVRIPSSCANGVCGT
CKSKLTSGTVDMNHNGGIRQREIDAGFFLPCCSKPLSDLVIER

Sequences:

>Translated_363_residues
MDTRNPQAPLAKATRHDVWNPEEDDTLVCLDVQQETHDVKTFTFASRDGKRFAFKAGQYFLFDLEHNGEPESRCYSISSS
PHRTNAFSVTVKRVPGGKISNWLHETLVPGASVKANGPLGHFVRSEAVKPKLLLLSGGSGITPVMSILRELADSCAPADV
VFMHAARTPLDLIFRDELACIARRLKGLRLHFLPETVAGEPSWSGLTGRISADYFRLAVPDIADRTVMCCGPAPFMAAAR
GIAAKLGVPAAHYLEESFDAAVIDEPEIPAIQEAAAKVFRVTFSKQARSIEVTGDQSVLSCAKKSGVRIPSSCANGVCGT
CKSKLTSGTVDMNHNGGIRQREIDAGFFLPCCSKPLSDLVIER
>Mature_363_residues
MDTRNPQAPLAKATRHDVWNPEEDDTLVCLDVQQETHDVKTFTFASRDGKRFAFKAGQYFLFDLEHNGEPESRCYSISSS
PHRTNAFSVTVKRVPGGKISNWLHETLVPGASVKANGPLGHFVRSEAVKPKLLLLSGGSGITPVMSILRELADSCAPADV
VFMHAARTPLDLIFRDELACIARRLKGLRLHFLPETVAGEPSWSGLTGRISADYFRLAVPDIADRTVMCCGPAPFMAAAR
GIAAKLGVPAAHYLEESFDAAVIDEPEIPAIQEAAAKVFRVTFSKQARSIEVTGDQSVLSCAKKSGVRIPSSCANGVCGT
CKSKLTSGTVDMNHNGGIRQREIDAGFFLPCCSKPLSDLVIER

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=332, Percent_Identity=31.3253012048193, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787658, Length=353, Percent_Identity=30.028328611898, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788104, Length=323, Percent_Identity=26.625386996904, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788903, Length=232, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323510, Length=198, Percent_Identity=29.7979797979798, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323552, Length=202, Percent_Identity=25.2475247524752, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322699, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39312; Mature: 39312

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRNPQAPLAKATRHDVWNPEEDDTLVCLDVQQETHDVKTFTFASRDGKRFAFKAGQYF
CCCCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCEE
LFDLEHNGEPESRCYSISSSPHRTNAFSVTVKRVPGGKISNWLHETLVPGASVKANGPLG
EEEECCCCCCHHHEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEECCCCHH
HFVRSEAVKPKLLLLSGGSGITPVMSILRELADSCAPADVVFMHAARTPLDLIFRDELAC
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
IARRLKGLRLHFLPETVAGEPSWSGLTGRISADYFRLAVPDIADRTVMCCGPAPFMAAAR
HHHHHCCCEEEECCHHHCCCCCCCCCEECCCCCEEEEECCCCCCCEEEEECCCHHHHHHH
GIAAKLGVPAAHYLEESFDAAVIDEPEIPAIQEAAAKVFRVTFSKQARSIEVTGDQSVLS
HHHHHCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHH
CAKKSGVRIPSSCANGVCGTCKSKLTSGTVDMNHNGGIRQREIDAGFFLPCCSKPLSDLV
HHHHCCCCCCHHHCCCCCHHHHHHHCCCCEEECCCCCCEEEECCCCEECHHHCCCHHHHH
IER
CCC
>Mature Secondary Structure
MDTRNPQAPLAKATRHDVWNPEEDDTLVCLDVQQETHDVKTFTFASRDGKRFAFKAGQYF
CCCCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCEE
LFDLEHNGEPESRCYSISSSPHRTNAFSVTVKRVPGGKISNWLHETLVPGASVKANGPLG
EEEECCCCCCHHHEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEECCCCHH
HFVRSEAVKPKLLLLSGGSGITPVMSILRELADSCAPADVVFMHAARTPLDLIFRDELAC
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
IARRLKGLRLHFLPETVAGEPSWSGLTGRISADYFRLAVPDIADRTVMCCGPAPFMAAAR
HHHHHCCCEEEECCHHHCCCCCCCCCEECCCCCEEEEECCCCCCCEEEEECCCHHHHHHH
GIAAKLGVPAAHYLEESFDAAVIDEPEIPAIQEAAAKVFRVTFSKQARSIEVTGDQSVLS
HHHHHCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHH
CAKKSGVRIPSSCANGVCGTCKSKLTSGTVDMNHNGGIRQREIDAGFFLPCCSKPLSDLV
HHHHCCCCCCHHHCCCCCHHHHHHHCCCCEEECCCCCCEEEECCCCEECHHHCCCHHHHH
IER
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]