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The map label for this gene is ygbM [C]

Identifier: 86361076

GI number: 86361076

Start: 387802

End: 388578

Strand: Direct

Name: ygbM [C]

Synonym: RHE_PF00346

Alternate gene names: 86361076

Gene position: 387802-388578 (Clockwise)

Preceding gene: 86361075

Following gene: 86361077

Centisome position: 60.36

GC content: 62.93

Gene sequence:

>777_bases
ATGCCAGTTTTCGCCGCCAACCTGACGATGATGTTCAGCGAATGGGACTTCCTCGACCGCTTCGACGCCGCAGCCGACGC
GGGGTTTTCCGCCGTCGAATACCTCTTCCCCTACGAGGCCGCACCGGATGCAATCGCCGAACGGCTTGCCCGCAACAATC
TGCGGCAGGCCCTGTTCAACCTGCCGCCGGGCGACTGGGGTGCGGGCGAGCGCGGCATCGCGGCTCTTCCCGGACGGTTC
GACGACCTCAAAGCGGATGTCGAGCGGGCATTGGACTATGCGGCGGCGACAGGCGTCGGGCGACTGCACCTGATGGCGGG
TATCGCCGACCCTCATGATCAAGAGGCCGCCGCCTCCTACCGACGCTCCGTCACCTACACTGCCGGCCGGCTTGCGGAAA
AAGGCGTTGATCTCCTGCTGGAGCCGATCAACGGGCGCAATATGCCGGGATATTTCCTCAACGACTTCGCGATCGCCGAG
CGGCTGATCGCCGAATGCGGCCTGCCCAACCTGAAGCTGCAATTCGACATCTATCACCGTCAGATCCTCCATGGCGACGT
TACGATGGCATTGCGGCGCCTGCTGCCGATCACCGGCCATATCCAGATCGCCGGCGTGCCGTCACGCAACGAGCCTGACG
GAGAGGAGCTGAACTATCCCTATCTGTTCGGTGAAATCGACCGGCTGGGTTACGACCGTTTCATCGGCTGCGAATATGTC
CCGCGCGGCCAGACACTGGACGGCCTTGGCTGGTTCAAACCTTTTGCACGGAGCTAG

Upstream 100 bases:

>100_bases
GCGACGATGATTCCTCGCTCGCACGCCTCTACGCCCAGCTTTCCGGCGCGCAATTGCCCGGTTTCGCCAAAGAGCCGCAA
GGCCGGTAAGGAGGGTCGAC

Downstream 100 bases:

>100_bases
ACCATGGCAATTTCACTTGGGTCGATCGCCGACGACTATACCGGCGCGTCCGACCTCGCAAACACGCTGACGAAAAACGG
CCTGCGCACGGTGCAGACGG

Product: putative hydroxypyruvate isomerase protein

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPVFAANLTMMFSEWDFLDRFDAAADAGFSAVEYLFPYEAAPDAIAERLARNNLRQALFNLPPGDWGAGERGIAALPGRF
DDLKADVERALDYAAATGVGRLHLMAGIADPHDQEAAASYRRSVTYTAGRLAEKGVDLLLEPINGRNMPGYFLNDFAIAE
RLIAECGLPNLKLQFDIYHRQILHGDVTMALRRLLPITGHIQIAGVPSRNEPDGEELNYPYLFGEIDRLGYDRFIGCEYV
PRGQTLDGLGWFKPFARS

Sequences:

>Translated_258_residues
MPVFAANLTMMFSEWDFLDRFDAAADAGFSAVEYLFPYEAAPDAIAERLARNNLRQALFNLPPGDWGAGERGIAALPGRF
DDLKADVERALDYAAATGVGRLHLMAGIADPHDQEAAASYRRSVTYTAGRLAEKGVDLLLEPINGRNMPGYFLNDFAIAE
RLIAECGLPNLKLQFDIYHRQILHGDVTMALRRLLPITGHIQIAGVPSRNEPDGEELNYPYLFGEIDRLGYDRFIGCEYV
PRGQTLDGLGWFKPFARS
>Mature_257_residues
PVFAANLTMMFSEWDFLDRFDAAADAGFSAVEYLFPYEAAPDAIAERLARNNLRQALFNLPPGDWGAGERGIAALPGRFD
DLKADVERALDYAAATGVGRLHLMAGIADPHDQEAAASYRRSVTYTAGRLAEKGVDLLLEPINGRNMPGYFLNDFAIAER
LIAECGLPNLKLQFDIYHRQILHGDVTMALRRLLPITGHIQIAGVPSRNEPDGEELNYPYLFGEIDRLGYDRFIGCEYVP
RGQTLDGLGWFKPFARS

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=261, Percent_Identity=43.2950191570881, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI300068964, Length=242, Percent_Identity=42.5619834710744, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1789095, Length=255, Percent_Identity=43.921568627451, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1786718, Length=257, Percent_Identity=41.2451361867704, Blast_Score=206, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17552022, Length=239, Percent_Identity=36.4016736401674, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17530883, Length=253, Percent_Identity=32.8063241106719, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 28657; Mature: 28526

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFAANLTMMFSEWDFLDRFDAAADAGFSAVEYLFPYEAAPDAIAERLARNNLRQALFN
CCEEECHHEEHHHHCHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
LPPGDWGAGERGIAALPGRFDDLKADVERALDYAAATGVGRLHLMAGIADPHDQEAAASY
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCHHHHHHH
RRSVTYTAGRLAEKGVDLLLEPINGRNMPGYFLNDFAIAERLIAECGLPNLKLQFDIYHR
HHHHHHHHHHHHHHCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
QILHGDVTMALRRLLPITGHIQIAGVPSRNEPDGEELNYPYLFGEIDRLGYDRFIGCEYV
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEECCHHHHCCCCEECCEEC
PRGQTLDGLGWFKPFARS
CCCCCCCCCHHCCHHHCC
>Mature Secondary Structure 
PVFAANLTMMFSEWDFLDRFDAAADAGFSAVEYLFPYEAAPDAIAERLARNNLRQALFN
CEEECHHEEHHHHCHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
LPPGDWGAGERGIAALPGRFDDLKADVERALDYAAATGVGRLHLMAGIADPHDQEAAASY
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCHHHHHHH
RRSVTYTAGRLAEKGVDLLLEPINGRNMPGYFLNDFAIAERLIAECGLPNLKLQFDIYHR
HHHHHHHHHHHHHHCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
QILHGDVTMALRRLLPITGHIQIAGVPSRNEPDGEELNYPYLFGEIDRLGYDRFIGCEYV
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEECCHHHHCCCCEECCEEC
PRGQTLDGLGWFKPFARS
CCCCCCCCCHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]