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The map label for this gene is 86360977

Identifier: 86360977

GI number: 86360977

Start: 263224

End: 264735

Strand: Direct

Name: 86360977

Synonym: RHE_PF00247

Alternate gene names: NA

Gene position: 263224-264735 (Clockwise)

Preceding gene: 86360975

Following gene: 86360979

Centisome position: 40.97

GC content: 60.58

Gene sequence:

>1512_bases
ATGACCGCGTTAGAAACCATGCTCAATCAACCCTACCTGCTTAGAACAAAAGCGCAACAGCCAGGCGACGGTGAAAACCT
GGAACTGGAAGGCTACGCCGAAAAAGCGGCCTTCCTGATCAATGGCAACCGATATTTCGCCGAGGTGGCGCGCACGCTGC
GGCAGGCACGGCGAAGTGTCTGGATCGTCGGGTGGGATTTCAATCCGGACATCCGGATGGAGCCGGAAAAATCCGACGAA
ACATTGGCAGATCTGCTGCATGCCTTGGCAGCGGCAAATCCGACACTCGAAATACGCATCCTCATCTGGGCCCTCGGGCC
GATCTATTCGGAAAAATCCCTGCAGGTGCTCCGCAAGAAAAACTTCCCGAGGAACGCCAGGATCGATCTGCGCTTCGATC
TTCAAAGCACGGTGCGCGGCTGCCACCATGAGAAACTCGTTTGCATCGACGACGCCGTCGCCTTCATCGGCGGCATGGAC
CTGACGTCGCGGCGATGGGATACGAGACGCCACCGCGCCTGGGACGCATTGCGACGCGACCCCGAAGGCGCGTCCTACGA
TCCGCTGCATGACGTTCAGGCAATGGTCACCGGCGACGCGGCCAGACTGATCGGGGATATCGCGCGGCGGCGCTGGCAAA
GCGCCACCGGCGAAAAGCATAACGCGCTTGCCGAAACCTCTTCCTTCACATGGCCGCGCGATCTTGCCGTTTCGCTGATG
CATATCCCCGTGAGCTTTGTGCTGACGGAGCCGGCAACCACATTGCGCGCCGGCATCAGCGATGGCATCGCCTCGACACT
CGGCATCATCGCCCGAGCACGGCGGCAGCTTTTCATCGAAGCGCAATATCTTGCCTCCTTCCGCGTCGCCGACGCTCTCG
CCGCGCGACTGCAAGAGGAAGATGGCCCCGAGATCATCGTCATCTGCACTCGTCGTTCTCATGGGCTGATCGAAAAGCTC
TTTATGGGCGGCAATCGAGACCGCGTCATCCGCCGTCTCAAGCGCACCGATCGTGCCGACCGGTTCAGGGTCTATTATCC
CGTCGTGCCCGGGCCGCCAGTGCCCGGGCCGGCAGCGCCCGGAAAGAACGACGAGGTGGAGGTGCTCATCCATTCCAAGC
TGATCATCGCAGATGACGAACTGATCCGCATCGGCTCCTCCAATCTCAACAATCGTTCGGAGGGATTGGATTCCGAATGC
GACATGCTTCTTGAGGCCGTCAATGACGAGCAGCGCGACGGAATAGCGGATCTGCGTCACCATTTGCTGGCCGAATATCT
CGGCACGACCACCGAGACCTTTGCCGCAGCCTTTGCGCAGAGCGGCTCGATCATCCAGGCAATCGACATGCTCAATGATG
GGCCTCGGGGCTTGCGGGAATTTGCCGTTGATTTGTCGGGCAGTATTTCGCCGATAAGGGGCACCGGGTTCTTCGACCCG
ACGCGGCCCGTCAAGCTGCTAAACCGACTGGGCCTCGGCGCGCTCTTCCGCCTCCTCGTCCGCCCCGCGTGA

Upstream 100 bases:

>100_bases
GCTGTGACATTTCTTTTCCTTACATTTTCCATCGCCGGCGGCGATCGGGAACCCGCGAAAGTTCCGGGCGTTTGCTTTCA
GTCAAAAGGCTGAGGCAACC

Downstream 100 bases:

>100_bases
CTGGCGGCGGAAGATTACTTCGCTGACGATGAAAAGCGCGGCGCCGAGCGCGAGCGGGAGGAAGAAATAGGTGCAGCGGA
AAGCAATCAGCGCGCCGATC

Product: phospholipase D protein

Products: NA

Alternate protein names: Phospholipase D; SNARE Associated Golgi Protein; Phospholipase D Family Protein; SNARE Associated Golgi Protein-Like Protein; SNARE Associated Golgi Protein-Related Protein; Phospholipase D Domain Protein; Transmembrane Phospholipase Protein; SNARE Associated Golgi Protein-Associated Protein; Phospholipase/Transphosphatidylase; Phospholipase D Alpha; Phospholipase Protein; Phospholipase D Active Site Motif Domain Protein; Phospholipase; Phospholipase D Protein; Phospholipase/Phosphatidylserine Synthase; Phospholipase D Superfamily Protein

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTALETMLNQPYLLRTKAQQPGDGENLELEGYAEKAAFLINGNRYFAEVARTLRQARRSVWIVGWDFNPDIRMEPEKSDE
TLADLLHALAAANPTLEIRILIWALGPIYSEKSLQVLRKKNFPRNARIDLRFDLQSTVRGCHHEKLVCIDDAVAFIGGMD
LTSRRWDTRRHRAWDALRRDPEGASYDPLHDVQAMVTGDAARLIGDIARRRWQSATGEKHNALAETSSFTWPRDLAVSLM
HIPVSFVLTEPATTLRAGISDGIASTLGIIARARRQLFIEAQYLASFRVADALAARLQEEDGPEIIVICTRRSHGLIEKL
FMGGNRDRVIRRLKRTDRADRFRVYYPVVPGPPVPGPAAPGKNDEVEVLIHSKLIIADDELIRIGSSNLNNRSEGLDSEC
DMLLEAVNDEQRDGIADLRHHLLAEYLGTTTETFAAAFAQSGSIIQAIDMLNDGPRGLREFAVDLSGSISPIRGTGFFDP
TRPVKLLNRLGLGALFRLLVRPA

Sequences:

>Translated_503_residues
MTALETMLNQPYLLRTKAQQPGDGENLELEGYAEKAAFLINGNRYFAEVARTLRQARRSVWIVGWDFNPDIRMEPEKSDE
TLADLLHALAAANPTLEIRILIWALGPIYSEKSLQVLRKKNFPRNARIDLRFDLQSTVRGCHHEKLVCIDDAVAFIGGMD
LTSRRWDTRRHRAWDALRRDPEGASYDPLHDVQAMVTGDAARLIGDIARRRWQSATGEKHNALAETSSFTWPRDLAVSLM
HIPVSFVLTEPATTLRAGISDGIASTLGIIARARRQLFIEAQYLASFRVADALAARLQEEDGPEIIVICTRRSHGLIEKL
FMGGNRDRVIRRLKRTDRADRFRVYYPVVPGPPVPGPAAPGKNDEVEVLIHSKLIIADDELIRIGSSNLNNRSEGLDSEC
DMLLEAVNDEQRDGIADLRHHLLAEYLGTTTETFAAAFAQSGSIIQAIDMLNDGPRGLREFAVDLSGSISPIRGTGFFDP
TRPVKLLNRLGLGALFRLLVRPA
>Mature_502_residues
TALETMLNQPYLLRTKAQQPGDGENLELEGYAEKAAFLINGNRYFAEVARTLRQARRSVWIVGWDFNPDIRMEPEKSDET
LADLLHALAAANPTLEIRILIWALGPIYSEKSLQVLRKKNFPRNARIDLRFDLQSTVRGCHHEKLVCIDDAVAFIGGMDL
TSRRWDTRRHRAWDALRRDPEGASYDPLHDVQAMVTGDAARLIGDIARRRWQSATGEKHNALAETSSFTWPRDLAVSLMH
IPVSFVLTEPATTLRAGISDGIASTLGIIARARRQLFIEAQYLASFRVADALAARLQEEDGPEIIVICTRRSHGLIEKLF
MGGNRDRVIRRLKRTDRADRFRVYYPVVPGPPVPGPAAPGKNDEVEVLIHSKLIIADDELIRIGSSNLNNRSEGLDSECD
MLLEAVNDEQRDGIADLRHHLLAEYLGTTTETFAAAFAQSGSIIQAIDMLNDGPRGLREFAVDLSGSISPIRGTGFFDPT
RPVKLLNRLGLGALFRLLVRPA

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI156564407, Length=161, Percent_Identity=31.6770186335404, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 56153; Mature: 56022

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALETMLNQPYLLRTKAQQPGDGENLELEGYAEKAAFLINGNRYFAEVARTLRQARRSV
CCHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHHCCE
WIVGWDFNPDIRMEPEKSDETLADLLHALAAANPTLEIRILIWALGPIYSEKSLQVLRKK
EEEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHC
NFPRNARIDLRFDLQSTVRGCHHEKLVCIDDAVAFIGGMDLTSRRWDTRRHRAWDALRRD
CCCCCCEEEEEECHHHHHCCCCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
PEGASYDPLHDVQAMVTGDAARLIGDIARRRWQSATGEKHNALAETSSFTWPRDLAVSLM
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHH
HIPVSFVLTEPATTLRAGISDGIASTLGIIARARRQLFIEAQYLASFRVADALAARLQEE
HCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGPEIIVICTRRSHGLIEKLFMGGNRDRVIRRLKRTDRADRFRVYYPVVPGPPVPGPAAP
CCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
GKNDEVEVLIHSKLIIADDELIRIGSSNLNNRSEGLDSECDMLLEAVNDEQRDGIADLRH
CCCCCEEEEEEEEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHCCCHHHHHH
HLLAEYLGTTTETFAAAFAQSGSIIQAIDMLNDGPRGLREFAVDLSGSISPIRGTGFFDP
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
TRPVKLLNRLGLGALFRLLVRPA
CHHHHHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure 
TALETMLNQPYLLRTKAQQPGDGENLELEGYAEKAAFLINGNRYFAEVARTLRQARRSV
CHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHHCCE
WIVGWDFNPDIRMEPEKSDETLADLLHALAAANPTLEIRILIWALGPIYSEKSLQVLRKK
EEEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHC
NFPRNARIDLRFDLQSTVRGCHHEKLVCIDDAVAFIGGMDLTSRRWDTRRHRAWDALRRD
CCCCCCEEEEEECHHHHHCCCCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
PEGASYDPLHDVQAMVTGDAARLIGDIARRRWQSATGEKHNALAETSSFTWPRDLAVSLM
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHH
HIPVSFVLTEPATTLRAGISDGIASTLGIIARARRQLFIEAQYLASFRVADALAARLQEE
HCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGPEIIVICTRRSHGLIEKLFMGGNRDRVIRRLKRTDRADRFRVYYPVVPGPPVPGPAAP
CCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
GKNDEVEVLIHSKLIIADDELIRIGSSNLNNRSEGLDSECDMLLEAVNDEQRDGIADLRH
CCCCCEEEEEEEEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHCCCHHHHHH
HLLAEYLGTTTETFAAAFAQSGSIIQAIDMLNDGPRGLREFAVDLSGSISPIRGTGFFDP
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
TRPVKLLNRLGLGALFRLLVRPA
CHHHHHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA