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The map label for this gene is dapAf2

Identifier: 86360968

GI number: 86360968

Start: 253248

End: 254198

Strand: Direct

Name: dapAf2

Synonym: RHE_PF00238

Alternate gene names: 86360968

Gene position: 253248-254198 (Clockwise)

Preceding gene: 86360967

Following gene: 86360969

Centisome position: 39.41

GC content: 66.14

Gene sequence:

>951_bases
ATGAGCATCGCGATCATGCGCAAGGCGCTTACGGGCGTATCGGGCGTGCCTGTCACGGCTTATGACGGCGGGGGCGAAGT
CGAACCCCGGATTACCGCGAAGGTTTATGCGCGGGTGGCGGCGGCGGGCATTCACAACATCGTCGCAGCCGGCAATACCG
GGGAATTCTACGCGCTGACGCCGCAAGAGATCCGCATCGTCCACGAAGCGGCGGTCGCGGGCGTCGACGGGCAAGCACCG
GTGACGGCGGCGGTCGGCCGGTCGCTACGCGAGGCGATCGGCATGGCTAAGGATGCGGCTGCGATCGGGGCATCAGCCGT
CATGTCGCACCAACCCGTCGACCCCTTCGCAGCACCTTCGGCCCAGATCGATTATTTCTGCAATCTCGCCGATGCGTCCG
CCCTGCCGCTCGTCGCCTATGTCAGGGCCGAGGGTTTTAGCGTCGCCGAGATCGTCCGCCTCGCCAATCACGGAAATATT
GCCGGCATCAAATTCGCGACGACCGACCTGATGCTGCTGTCGCGCGCGATCCCCGCCGCCGATCCGAATGGCGCGCTGTT
CGTCTGCGGCCTGGCAGAAAGCTGGGCGCCGACATTCACCGCAGCCGGCGCGCGCGGCTTCACGTCAGGCCTCGTCAACG
TCGCGCCAAAGCTTTCGCTCGCCGTCCAGGACTCGCTTGAAAAGGGCGATTTCGCCGCGGCGAGAGCAATCGTCGGCAAG
CTCGAACCCTTCGAGCGGATGCGGACCAAATTCCGCAACGGCGCGAACGTCACGGTCGTGAAGGAGGCCGTCACCTATTC
CGGCCTCGATGTCGGGCCGGTGCGCGTGCCGGGATTGCCGCAGCTCGATCAGCAGGACCGCGAGGAGCTGCACCGCCTGC
TTCGAGGCTGGGAGGCCGAGGGCGACATTCAAACGCAGCAGGACCGGCAGGCCGTGAAGGCTGCCGGCTGA

Upstream 100 bases:

>100_bases
AGGCGGGCACGGTCATCGCCTTCGACGTGGATGCGGAGGGGCTGCCGCCTTTCCGCTTCGGCAAGCAATCATCTTGATGG
AAAGCGAACGGGGGAGAAAA

Downstream 100 bases:

>100_bases
GTTCGAACATTCTTCTGCAAGCAACCGGCGCGGGATGGCGCCACGAGATTGGGAGGTCTTGAGATGCTGAAACAGCTATT
GACGACAATCGCAGTTACCG

Product: dihydrodipicolinate synthase protein

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase 1; KDGDH 1 [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSIAIMRKALTGVSGVPVTAYDGGGEVEPRITAKVYARVAAAGIHNIVAAGNTGEFYALTPQEIRIVHEAAVAGVDGQAP
VTAAVGRSLREAIGMAKDAAAIGASAVMSHQPVDPFAAPSAQIDYFCNLADASALPLVAYVRAEGFSVAEIVRLANHGNI
AGIKFATTDLMLLSRAIPAADPNGALFVCGLAESWAPTFTAAGARGFTSGLVNVAPKLSLAVQDSLEKGDFAAARAIVGK
LEPFERMRTKFRNGANVTVVKEAVTYSGLDVGPVRVPGLPQLDQQDREELHRLLRGWEAEGDIQTQQDRQAVKAAG

Sequences:

>Translated_316_residues
MSIAIMRKALTGVSGVPVTAYDGGGEVEPRITAKVYARVAAAGIHNIVAAGNTGEFYALTPQEIRIVHEAAVAGVDGQAP
VTAAVGRSLREAIGMAKDAAAIGASAVMSHQPVDPFAAPSAQIDYFCNLADASALPLVAYVRAEGFSVAEIVRLANHGNI
AGIKFATTDLMLLSRAIPAADPNGALFVCGLAESWAPTFTAAGARGFTSGLVNVAPKLSLAVQDSLEKGDFAAARAIVGK
LEPFERMRTKFRNGANVTVVKEAVTYSGLDVGPVRVPGLPQLDQQDREELHRLLRGWEAEGDIQTQQDRQAVKAAG
>Mature_315_residues
SIAIMRKALTGVSGVPVTAYDGGGEVEPRITAKVYARVAAAGIHNIVAAGNTGEFYALTPQEIRIVHEAAVAGVDGQAPV
TAAVGRSLREAIGMAKDAAAIGASAVMSHQPVDPFAAPSAQIDYFCNLADASALPLVAYVRAEGFSVAEIVRLANHGNIA
GIKFATTDLMLLSRAIPAADPNGALFVCGLAESWAPTFTAAGARGFTSGLVNVAPKLSLAVQDSLEKGDFAAARAIVGKL
EPFERMRTKFRNGANVTVVKEAVTYSGLDVGPVRVPGLPQLDQQDREELHRLLRGWEAEGDIQTQQDRQAVKAAG

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI87082415, Length=300, Percent_Identity=25.3333333333333, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786463, Length=288, Percent_Identity=25.6944444444444, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 32942; Mature: 32811

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAIMRKALTGVSGVPVTAYDGGGEVEPRITAKVYARVAAAGIHNIVAAGNTGEFYALT
CCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEC
PQEIRIVHEAAVAGVDGQAPVTAAVGRSLREAIGMAKDAAAIGASAVMSHQPVDPFAAPS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
AQIDYFCNLADASALPLVAYVRAEGFSVAEIVRLANHGNIAGIKFATTDLMLLSRAIPAA
CCHHEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCC
DPNGALFVCGLAESWAPTFTAAGARGFTSGLVNVAPKLSLAVQDSLEKGDFAAARAIVGK
CCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHC
LEPFERMRTKFRNGANVTVVKEAVTYSGLDVGPVRVPGLPQLDQQDREELHRLLRGWEAE
CCHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
GDIQTQQDRQAVKAAG
CCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SIAIMRKALTGVSGVPVTAYDGGGEVEPRITAKVYARVAAAGIHNIVAAGNTGEFYALT
CHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEC
PQEIRIVHEAAVAGVDGQAPVTAAVGRSLREAIGMAKDAAAIGASAVMSHQPVDPFAAPS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
AQIDYFCNLADASALPLVAYVRAEGFSVAEIVRLANHGNIAGIKFATTDLMLLSRAIPAA
CCHHEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCC
DPNGALFVCGLAESWAPTFTAAGARGFTSGLVNVAPKLSLAVQDSLEKGDFAAARAIVGK
CCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHC
LEPFERMRTKFRNGANVTVVKEAVTYSGLDVGPVRVPGLPQLDQQDREELHRLLRGWEAE
CCHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
GDIQTQQDRQAVKAAG
CCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]