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The map label for this gene is ygjG [C]

Identifier: 86360933

GI number: 86360933

Start: 212845

End: 214224

Strand: Direct

Name: ygjG [C]

Synonym: RHE_PF00202

Alternate gene names: 86360933

Gene position: 212845-214224 (Clockwise)

Preceding gene: 86360932

Following gene: 86360934

Centisome position: 33.13

GC content: 61.23

Gene sequence:

>1380_bases
ATGCTCGACAAAAGCAATGAACTTACCGCCTGGGACCGCGATCATTTCTTCCATCCCTCCACCCACATGGGCATGCATGC
GCGCGGCGAGACGCCGACGCGCGTCGTCGCCGAAGGGGAAGGCGTCTACATCACCGACACGAGCGGCCGCAAAAGCCTCG
ATGCCTTTGCCGGACTTTATTGTGTCAATGTCGGCTACGGCCGCCAGGAGATCGCCGACGCTATCGCCGAACAGGCGAAG
AACCTAGCCTATTACCACGCCTATGTCGGCCACGGCACGGAAGCATCGATTACGCTTGCGAAAATGATTATCGACCGCGC
ACCTGCGGGCATGAGCCGCGTCTACTTCGGCCTTTCCGGCTCGGATGCCAACGAGACCAACATCAAGCTGATCTGGTACT
ACAACAACATTCTCGGCCGGCCGGAAAAGAAGAAGATCATCTCGCGCTGGCGCGGCTATCACGGCTCCGGTGTCATGACC
GGCAGCCTCACCGGTCTTGCGCTTTTTCACAATGCCTTCGATCTGCCGCGCGCCCCGATCCTCCACACCGAAGCGCCCTA
TTATTTCCGCCGGCCTGACCGCTCGATGAGCGAGGAGCAATTCTCGCAATATTGCGCCGACAGACTGGAGGAGATGATTA
TCGCCGAGGGGCCTGACACCATCGCCGCCTTCATCGGCGAACCAATCCTCGGCACCGGCGGCATCGTCCCGCCCCCCCAG
GGCTACTGGCCGAAGATCCAGGCCGTGCTCGACAGATACGATATCCTGCTGGTCGCCGACGAGGTCGTCACCGGCTTCGG
CCGTCTCGGCACGATGTTCGGCTCGGATCACTACGGCATGAAGCCGGACCTGATCACCATCGCCAAAGGCCTGACCTCGG
CCTATGCTCCGCTTTCCGGCTCGATCGTTTCAACCAAAATATGGCAGGTGCTGGTGCAGGGCTCCGATCAGCTCGGCGCA
ATCGGCCATGGCTGGACCTATTCCGCCCATCCGATCTGCGCTGCCGCAGGTATCGCCAATCTGGAATTAATCGACGAACT
CGGCATCGTCGACAATGCCGGCACGACCGGCAGCTATTTCCGGTCGCAGTTGCAAGAGGCGGTTGGCGGCCATCGGAATG
TCGGTGAAGTCCGCGGCGACGGTCTGATGGCCGCTGTCGAATTCGTCGAGGACAGGGACGACCGCCGGTTCTTCGATCCC
GGCCGCAAGATCGGTCCGCAGGTCGCATCCGCCCTACTCGAACGTGGCGTCATCGGCCGCGCCATGCCGCAGGGCGATAT
TCTCGGCTTCGCTCCACCACTCTGCCTCACCCGCGAAGAAGCAGACGTCGTCGTCAAGGCGGCTGCGGACGCGATCGAAA
GTGTTTTCAAAACCATCTGA

Upstream 100 bases:

>100_bases
GCTTAAAGCTCTTTGTTTTTATGCATGTCGTTATCCCGGAACCGCGGCACACTTCCGGGCGACATGCACTAACCGCACCA
TTTCAAGAAGAGGACAGGAC

Downstream 100 bases:

>100_bases
GGAGAAGAGCCGCATGACGATCCCGGAAAAGATGGCGGCGGTGTTGCTCACCGGCCATGGCGGCCTGGAAAAGCTCGTCT
ACGACAGGGACTTTCCTGTT

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLDKSNELTAWDRDHFFHPSTHMGMHARGETPTRVVAEGEGVYITDTSGRKSLDAFAGLYCVNVGYGRQEIADAIAEQAK
NLAYYHAYVGHGTEASITLAKMIIDRAPAGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMT
GSLTGLALFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCADRLEEMIIAEGPDTIAAFIGEPILGTGGIVPPPQ
GYWPKIQAVLDRYDILLVADEVVTGFGRLGTMFGSDHYGMKPDLITIAKGLTSAYAPLSGSIVSTKIWQVLVQGSDQLGA
IGHGWTYSAHPICAAAGIANLELIDELGIVDNAGTTGSYFRSQLQEAVGGHRNVGEVRGDGLMAAVEFVEDRDDRRFFDP
GRKIGPQVASALLERGVIGRAMPQGDILGFAPPLCLTREEADVVVKAAADAIESVFKTI

Sequences:

>Translated_459_residues
MLDKSNELTAWDRDHFFHPSTHMGMHARGETPTRVVAEGEGVYITDTSGRKSLDAFAGLYCVNVGYGRQEIADAIAEQAK
NLAYYHAYVGHGTEASITLAKMIIDRAPAGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMT
GSLTGLALFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCADRLEEMIIAEGPDTIAAFIGEPILGTGGIVPPPQ
GYWPKIQAVLDRYDILLVADEVVTGFGRLGTMFGSDHYGMKPDLITIAKGLTSAYAPLSGSIVSTKIWQVLVQGSDQLGA
IGHGWTYSAHPICAAAGIANLELIDELGIVDNAGTTGSYFRSQLQEAVGGHRNVGEVRGDGLMAAVEFVEDRDDRRFFDP
GRKIGPQVASALLERGVIGRAMPQGDILGFAPPLCLTREEADVVVKAAADAIESVFKTI
>Mature_459_residues
MLDKSNELTAWDRDHFFHPSTHMGMHARGETPTRVVAEGEGVYITDTSGRKSLDAFAGLYCVNVGYGRQEIADAIAEQAK
NLAYYHAYVGHGTEASITLAKMIIDRAPAGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMT
GSLTGLALFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCADRLEEMIIAEGPDTIAAFIGEPILGTGGIVPPPQ
GYWPKIQAVLDRYDILLVADEVVTGFGRLGTMFGSDHYGMKPDLITIAKGLTSAYAPLSGSIVSTKIWQVLVQGSDQLGA
IGHGWTYSAHPICAAAGIANLELIDELGIVDNAGTTGSYFRSQLQEAVGGHRNVGEVRGDGLMAAVEFVEDRDDRRFFDP
GRKIGPQVASALLERGVIGRAMPQGDILGFAPPLCLTREEADVVVKAAADAIESVFKTI

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=444, Percent_Identity=26.1261261261261, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4557809, Length=460, Percent_Identity=25.6521739130435, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=25.531914893617, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=25.9433962264151, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI226442709, Length=358, Percent_Identity=26.8156424581006, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=24.8837209302326, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI284507298, Length=240, Percent_Identity=29.5833333333333, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=26.3285024154589, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1787560, Length=416, Percent_Identity=29.3269230769231, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=28.125, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=25.7142857142857, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=26.044226044226, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786991, Length=459, Percent_Identity=25.7080610021786, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786349, Length=324, Percent_Identity=25.6172839506173, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564660, Length=453, Percent_Identity=29.3598233995585, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25144271, Length=445, Percent_Identity=25.8426966292135, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25144274, Length=235, Percent_Identity=29.7872340425532, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71992977, Length=424, Percent_Identity=25, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=434, Percent_Identity=29.2626728110599, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324432, Length=421, Percent_Identity=23.9904988123515, Blast_Score=106, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=364, Percent_Identity=25.2747252747253, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321456, Length=310, Percent_Identity=26.7741935483871, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161085790, Length=444, Percent_Identity=29.2792792792793, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28574759, Length=443, Percent_Identity=28.8939051918736, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21356575, Length=438, Percent_Identity=24.2009132420091, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357415, Length=423, Percent_Identity=26.0047281323877, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI281366494, Length=282, Percent_Identity=25.177304964539, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667139, Length=282, Percent_Identity=25.177304964539, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667143, Length=282, Percent_Identity=25.177304964539, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49922; Mature: 49922

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSNELTAWDRDHFFHPSTHMGMHARGETPTRVVAEGEGVYITDTSGRKSLDAFAGLY
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHCEE
CVNVGYGRQEIADAIAEQAKNLAYYHAYVGHGTEASITLAKMIIDRAPAGMSRVYFGLSG
EEECCCCHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
SDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMTGSLTGLALFHNAFDLPRAPI
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHCCCCCCE
LHTEAPYYFRRPDRSMSEEQFSQYCADRLEEMIIAEGPDTIAAFIGEPILGTGGIVPPPQ
EECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
GYWPKIQAVLDRYDILLVADEVVTGFGRLGTMFGSDHYGMKPDLITIAKGLTSAYAPLSG
CCCHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
SIVSTKIWQVLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGIVDNAGTTGSYF
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCCCCCCCHHHH
RSQLQEAVGGHRNVGEVRGDGLMAAVEFVEDRDDRRFFDPGRKIGPQVASALLERGVIGR
HHHHHHHHCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHCCCCCC
AMPQGDILGFAPPLCLTREEADVVVKAAADAIESVFKTI
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDKSNELTAWDRDHFFHPSTHMGMHARGETPTRVVAEGEGVYITDTSGRKSLDAFAGLY
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHCEE
CVNVGYGRQEIADAIAEQAKNLAYYHAYVGHGTEASITLAKMIIDRAPAGMSRVYFGLSG
EEECCCCHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
SDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMTGSLTGLALFHNAFDLPRAPI
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHCCCCCCE
LHTEAPYYFRRPDRSMSEEQFSQYCADRLEEMIIAEGPDTIAAFIGEPILGTGGIVPPPQ
EECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
GYWPKIQAVLDRYDILLVADEVVTGFGRLGTMFGSDHYGMKPDLITIAKGLTSAYAPLSG
CCCHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
SIVSTKIWQVLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGIVDNAGTTGSYF
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCCCCCCCHHHH
RSQLQEAVGGHRNVGEVRGDGLMAAVEFVEDRDDRRFFDPGRKIGPQVASALLERGVIGR
HHHHHHHHCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHCCCCCC
AMPQGDILGFAPPLCLTREEADVVVKAAADAIESVFKTI
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]