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The map label for this gene is mcpA [H]

Identifier: 86360909

GI number: 86360909

Start: 188245

End: 189684

Strand: Direct

Name: mcpA [H]

Synonym: RHE_PF00178

Alternate gene names: 86360909

Gene position: 188245-189684 (Clockwise)

Preceding gene: 86360908

Following gene: 86360920

Centisome position: 29.3

GC content: 62.92

Gene sequence:

>1440_bases
ATGAACCGCGAAATCATCCCCGCCTTGAACGCGAAGGACGAAAGTAAGGCGCATGGTGCGATCGAGCAGTTGCGCGTCGC
CTTCCATGCGCATCAGGATGCTGTGGAGAAACTCGTTGCAAATTCCGACGCTTTCCTGAAAGGCGAAGAGAGCAATGCCG
CTTCGGAAATCATAACCTGGACGATCTATGCGGGCGCCGCGGGCTTCGGTTCCTTCGCCCTGCTGCTGGTCGGGCTCTAT
TTTTTGCGCCGTCGAGCCATCGTGCCGCTGGATGGCATGAAGGCCTATATGGGCAACCTCGCCGAAGGCGATTTTTCAAC
CGAAGTCCCCTACGCCAACCGCTCCGACGAGATCGGCGCCATGTCCAAGGCTGTGGCGGTGTTCCGCCGCAATGCGCTGG
AACGGCAAGACGCACAGAAACGCGAAACCGCGCTTCGCGATCAGGAATTCCAGCGTGAGCGTAGCCAGATGGCTGAAAAG
GCTGCCGAGGAGCAGCGACGCGAAGCGGTGATCGAGGCGCTGACCTACGGCCTGGATCAGCTCTCGCTTGGCAATCTCGA
TTGCCGGATCACCACAGCCTTCGCCCCCGCTTACGAGACGTTGCGGGCGAAATTCAACAACAGCATGAATGCGCTTGGCG
CCTCGATGGCGGAGATCTCCCGGACATCCAGGCAGGTGGGCAGCTCTTCCGCCGGCATCACGGAGGCCGCCGACAGCCTT
GCATCACGCACCGAACAGCAGGCCGCGATGCTCGAAGAGGCGACCGCCGCGCTCGGCGAAATGAACGCCAAGACGAAGGA
CGCTTCCGATCATGCCGGCAAGGCGACCGGAATGATGGCCGAGACTCGCAGCAGCGCCGAACATTCGGCCGCCGTCGTTC
GCGAAGCGATCGACGCCATGCAAAGGATCGAAGGCTCGTCCGCCCAGATCGGCGAGATCGTCAACGTCATCGACGAGATC
GCCTTCCAGACCAATCTCCTGGCGCTCAATGCCGGCGTCGAGGCCGCCCGGGCCGGCGAGGCGGGCAAGGGTTTCGCCGT
CGTGGCGCAGGAAGTGCGCGAGCTCGCCCTCCGCTCGGCCAACGCCGCCAAGGAGATCAGATCTCTGATTTCCACATCAT
CGTCTGAGGTTTCCACAGGCGTGGAGCTCGTCAACCGTACCGGCAAGGCGCTTATGGAGATCGAAGGCCAGGTCGAGCAG
GTTGCCGGCCTGATCGCCCGCATCGTTTCGGTATCTTCCGAGCAGGCCGTGGCGATCGGGGAAATCAACGCCTCCGTCAA
TGCGCTCGACGAGGTCACGCAGCGCAACGCCGCCATGGCTGCGGAAACCGTCTCGGCCTGCCGCGCGCTCGGCGGCCAGA
CGCAGACGCTGGAAGGCGTTGTCAGCCGCTTCCAGATCGATGCGGCAGCTGCCGGATCGAGATCGCCGAAAGCGGCTTGA

Upstream 100 bases:

>100_bases
CGACCGTCGCGCCTATTGGAAAACCACCCGGCTGCCGCAGTCTTTGAAGGATGAGCTCGAAAACGATGTGCTCGCCAAGG
GCGATGTATTCTGGCAGGTG

Downstream 100 bases:

>100_bases
GATGGCCGGCCGGCGAAACGCATCTCGCCGCGCCTGCCCGTCATCTCAGCGCGTCACCGTCGCGATCACCGCAACGCAGT
CGCCTGGTTTGACGAGCCCC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MNREIIPALNAKDESKAHGAIEQLRVAFHAHQDAVEKLVANSDAFLKGEESNAASEIITWTIYAGAAGFGSFALLLVGLY
FLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQDAQKRETALRDQEFQRERSQMAEK
AAEEQRREAVIEALTYGLDQLSLGNLDCRITTAFAPAYETLRAKFNNSMNALGASMAEISRTSRQVGSSSAGITEAADSL
ASRTEQQAAMLEEATAALGEMNAKTKDASDHAGKATGMMAETRSSAEHSAAVVREAIDAMQRIEGSSAQIGEIVNVIDEI
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELALRSANAAKEIRSLISTSSSEVSTGVELVNRTGKALMEIEGQVEQ
VAGLIARIVSVSSEQAVAIGEINASVNALDEVTQRNAAMAAETVSACRALGGQTQTLEGVVSRFQIDAAAAGSRSPKAA

Sequences:

>Translated_479_residues
MNREIIPALNAKDESKAHGAIEQLRVAFHAHQDAVEKLVANSDAFLKGEESNAASEIITWTIYAGAAGFGSFALLLVGLY
FLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQDAQKRETALRDQEFQRERSQMAEK
AAEEQRREAVIEALTYGLDQLSLGNLDCRITTAFAPAYETLRAKFNNSMNALGASMAEISRTSRQVGSSSAGITEAADSL
ASRTEQQAAMLEEATAALGEMNAKTKDASDHAGKATGMMAETRSSAEHSAAVVREAIDAMQRIEGSSAQIGEIVNVIDEI
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELALRSANAAKEIRSLISTSSSEVSTGVELVNRTGKALMEIEGQVEQ
VAGLIARIVSVSSEQAVAIGEINASVNALDEVTQRNAAMAAETVSACRALGGQTQTLEGVVSRFQIDAAAAGSRSPKAA
>Mature_479_residues
MNREIIPALNAKDESKAHGAIEQLRVAFHAHQDAVEKLVANSDAFLKGEESNAASEIITWTIYAGAAGFGSFALLLVGLY
FLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQDAQKRETALRDQEFQRERSQMAEK
AAEEQRREAVIEALTYGLDQLSLGNLDCRITTAFAPAYETLRAKFNNSMNALGASMAEISRTSRQVGSSSAGITEAADSL
ASRTEQQAAMLEEATAALGEMNAKTKDASDHAGKATGMMAETRSSAEHSAAVVREAIDAMQRIEGSSAQIGEIVNVIDEI
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELALRSANAAKEIRSLISTSSSEVSTGVELVNRTGKALMEIEGQVEQ
VAGLIARIVSVSSEQAVAIGEINASVNALDEVTQRNAAMAAETVSACRALGGQTQTLEGVVSRFQIDAAAAGSRSPKAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=238, Percent_Identity=44.9579831932773, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1788194, Length=304, Percent_Identity=36.5131578947368, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI2367378, Length=211, Percent_Identity=44.5497630331754, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787690, Length=257, Percent_Identity=38.1322957198444, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=39.9122807017544, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 50763; Mature: 50763

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNREIIPALNAKDESKAHGAIEQLRVAFHAHQDAVEKLVANSDAFLKGEESNAASEIITW
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEE
TIYAGAAGFGSFALLLVGLYFLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGA
EEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
MSKAVAVFRRNALERQDAQKRETALRDQEFQRERSQMAEKAAEEQRREAVIEALTYGLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LSLGNLDCRITTAFAPAYETLRAKFNNSMNALGASMAEISRTSRQVGSSSAGITEAADSL
CCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ASRTEQQAAMLEEATAALGEMNAKTKDASDHAGKATGMMAETRSSAEHSAAVVREAIDAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIEGSSAQIGEIVNVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELALRSA
HHCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCC
NAAKEIRSLISTSSSEVSTGVELVNRTGKALMEIEGQVEQVAGLIARIVSVSSEQAVAIG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
EINASVNALDEVTQRNAAMAAETVSACRALGGQTQTLEGVVSRFQIDAAAAGSRSPKAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNREIIPALNAKDESKAHGAIEQLRVAFHAHQDAVEKLVANSDAFLKGEESNAASEIITW
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEE
TIYAGAAGFGSFALLLVGLYFLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGA
EEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
MSKAVAVFRRNALERQDAQKRETALRDQEFQRERSQMAEKAAEEQRREAVIEALTYGLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LSLGNLDCRITTAFAPAYETLRAKFNNSMNALGASMAEISRTSRQVGSSSAGITEAADSL
CCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ASRTEQQAAMLEEATAALGEMNAKTKDASDHAGKATGMMAETRSSAEHSAAVVREAIDAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIEGSSAQIGEIVNVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELALRSA
HHCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCC
NAAKEIRSLISTSSSEVSTGVELVNRTGKALMEIEGQVEQVAGLIARIVSVSSEQAVAIG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
EINASVNALDEVTQRNAAMAAETVSACRALGGQTQTLEGVVSRFQIDAAAAGSRSPKAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]