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The map label for this gene is argE [H]

Identifier: 85860793

GI number: 85860793

Start: 2960611

End: 2961744

Strand: Direct

Name: argE [H]

Synonym: SYN_00326

Alternate gene names: 85860793

Gene position: 2960611-2961744 (Clockwise)

Preceding gene: 85860792

Following gene: 85860797

Centisome position: 93.12

GC content: 58.82

Gene sequence:

>1134_bases
ATGACCAGCGACCTGAAACGCGTCGAGAGGGCGATCTATCCAGCCAGACTGCGGAAAACGCTTCTGGATCTCCTCGATAT
CTATTCCCCGTCCGGAAAGGAAGAGGATATGCAGCTCTACCTGACCGAGATCCTCGAAAGAGGGGGGGCGGTCGTGAAAC
GTCAGGAGGTGGAGGAGGAACGCTACAACCTCCTTGTCACCATGGGAAAGGGCGAGCCCCTGCTCTATCTCGTCGGCCAC
GTGGATACCATCCCCGCCTGGGATCTGGAGTCCTCCGGACCAAACGAAGAAAACGGCATCTTTTACGGTCTGGGAAGCGC
GGACATGAAAGGAGGCTGCGCGGCGATGGTGGAAACCTGGCTGGCCCTTTCCGAGGCCCTTCCTTCCGCTGAACGGCCGC
CGGTCGGTCTGCTGCTGGTCGTCGGCGAGGAAGAAAATGGAGACGGCAGCGCCGCTTTTCTTGAATCCCGCCGCCCTCCC
TGGGTCATCATCGGTGAACCGACCGGCCTGGCGCCCTGTTTTGCCCATTACGGTTATCTGGAAGCCAGCTTTATCACGAG
CGGCCTCAGGAGCCACTCGTCCCTTCCCGAACTGGGACACAACGCCGTGGAATCCATGCTGCGGCTCCTGCTGCATCTGG
GGAAAAACGCCCTGTTCAACCGGGAGGAGTCGGATATCGTCTATTCGATCCGTGAAATGAGCTCTTCTCCCGCAGGGTTT
GTCGTTCCTGACCGCTGCGAAACCTGGATCGATCTCCACCTTCCGCCCGGCAGGGAACCGGAAATCGTCCAGGAGGCGAT
CCGCCGGATCGTCGCGGAGGCGCACCGGTACATTCCTGATCTGGTCGTGGAGGTGAACTTTGATTTCACTTTCGGCGGTT
ATGATCTCGGCTCCGAAAACCGGATGGCAAGCTGCTTAAAAGAGATCTACGCCGAATTGAATTTGCCCTTTCGCCTTGAT
TCCTTCCGCTCCCATTCCGACGGCAACCTTTTCTTCGCGGCGGGAACGAACCCCTTGATTCTCGGTCCCGGCTCCCTGGA
AACAGCCCATACGCCGGACGAGCAGGTTCTTTTCGAGGACGTATTGACGGCGGCCCGAATTTATGCCGCCCTCTGCCTGA
AGTTTTCTGCGTGA

Upstream 100 bases:

>100_bases
TCTCCTTCTTTCAGAAGATGGGATTCAAGGACAGGCAGGAACACGTATTCCTGTCCCTCAACCTCACCCGCAGAACCAAA
AAGCCCAGGAAAAAGAAGCC

Downstream 100 bases:

>100_bases
ACCACCCGCCTCCGGGGAAATGATCCTTTACCAAATTATTGCCCGGAAAGAAGGGCGTTTTGTAATTATCGGGCAGGGAA
GAGAAAAACGATACGATTTC

Product: acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like protein

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTSDLKRVERAIYPARLRKTLLDLLDIYSPSGKEEDMQLYLTEILERGGAVVKRQEVEEERYNLLVTMGKGEPLLYLVGH
VDTIPAWDLESSGPNEENGIFYGLGSADMKGGCAAMVETWLALSEALPSAERPPVGLLLVVGEEENGDGSAAFLESRRPP
WVIIGEPTGLAPCFAHYGYLEASFITSGLRSHSSLPELGHNAVESMLRLLLHLGKNALFNREESDIVYSIREMSSSPAGF
VVPDRCETWIDLHLPPGREPEIVQEAIRRIVAEAHRYIPDLVVEVNFDFTFGGYDLGSENRMASCLKEIYAELNLPFRLD
SFRSHSDGNLFFAAGTNPLILGPGSLETAHTPDEQVLFEDVLTAARIYAALCLKFSA

Sequences:

>Translated_377_residues
MTSDLKRVERAIYPARLRKTLLDLLDIYSPSGKEEDMQLYLTEILERGGAVVKRQEVEEERYNLLVTMGKGEPLLYLVGH
VDTIPAWDLESSGPNEENGIFYGLGSADMKGGCAAMVETWLALSEALPSAERPPVGLLLVVGEEENGDGSAAFLESRRPP
WVIIGEPTGLAPCFAHYGYLEASFITSGLRSHSSLPELGHNAVESMLRLLLHLGKNALFNREESDIVYSIREMSSSPAGF
VVPDRCETWIDLHLPPGREPEIVQEAIRRIVAEAHRYIPDLVVEVNFDFTFGGYDLGSENRMASCLKEIYAELNLPFRLD
SFRSHSDGNLFFAAGTNPLILGPGSLETAHTPDEQVLFEDVLTAARIYAALCLKFSA
>Mature_376_residues
TSDLKRVERAIYPARLRKTLLDLLDIYSPSGKEEDMQLYLTEILERGGAVVKRQEVEEERYNLLVTMGKGEPLLYLVGHV
DTIPAWDLESSGPNEENGIFYGLGSADMKGGCAAMVETWLALSEALPSAERPPVGLLLVVGEEENGDGSAAFLESRRPPW
VIIGEPTGLAPCFAHYGYLEASFITSGLRSHSSLPELGHNAVESMLRLLLHLGKNALFNREESDIVYSIREMSSSPAGFV
VPDRCETWIDLHLPPGREPEIVQEAIRRIVAEAHRYIPDLVVEVNFDFTFGGYDLGSENRMASCLKEIYAELNLPFRLDS
FRSHSDGNLFFAAGTNPLILGPGSLETAHTPDEQVLFEDVLTAARIYAALCLKFSA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=335, Percent_Identity=26.2686567164179, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789236, Length=395, Percent_Identity=25.8227848101266, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551016, Length=206, Percent_Identity=29.6116504854369, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41661; Mature: 41530

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDLKRVERAIYPARLRKTLLDLLDIYSPSGKEEDMQLYLTEILERGGAVVKRQEVEEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
RYNLLVTMGKGEPLLYLVGHVDTIPAWDLESSGPNEENGIFYGLGSADMKGGCAAMVETW
HCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHH
LALSEALPSAERPPVGLLLVVGEEENGDGSAAFLESRRPPWVIIGEPTGLAPCFAHYGYL
HHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHCCH
EASFITSGLRSHSSLPELGHNAVESMLRLLLHLGKNALFNREESDIVYSIREMSSSPAGF
HHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCCCC
VVPDRCETWIDLHLPPGREPEIVQEAIRRIVAEAHRYIPDLVVEVNFDFTFGGYDLGSEN
EECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCH
RMASCLKEIYAELNLPFRLDSFRSHSDGNLFFAAGTNPLILGPGSLETAHTPDEQVLFED
HHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHHHHHH
VLTAARIYAALCLKFSA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSDLKRVERAIYPARLRKTLLDLLDIYSPSGKEEDMQLYLTEILERGGAVVKRQEVEEE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
RYNLLVTMGKGEPLLYLVGHVDTIPAWDLESSGPNEENGIFYGLGSADMKGGCAAMVETW
HCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHH
LALSEALPSAERPPVGLLLVVGEEENGDGSAAFLESRRPPWVIIGEPTGLAPCFAHYGYL
HHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHCCH
EASFITSGLRSHSSLPELGHNAVESMLRLLLHLGKNALFNREESDIVYSIREMSSSPAGF
HHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCCCC
VVPDRCETWIDLHLPPGREPEIVQEAIRRIVAEAHRYIPDLVVEVNFDFTFGGYDLGSEN
EECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCH
RMASCLKEIYAELNLPFRLDSFRSHSDGNLFFAAGTNPLILGPGSLETAHTPDEQVLFED
HHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHHHHHH
VLTAARIYAALCLKFSA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA